Liability in Software Engineering: Overview of the LISE Approach and Illustration on a Case Study

© ACM – 2010. This is the authors' pre-version of the work. It is posted here by permission of ACM for your personal use. Not for redistribution. The definitive version was published in the Proceedings of the 32nd ACM/IEEE international Conference on Software Engineering (ICSE'10) - Volume 1 – 978-1-60558-719-6/10/05 – (May 2-8 – 2010) http://doi.acm.org/10.1145/1806799.1806823LISE is a multidisciplinary project involving lawyers and computer scientists with the aim to put forward a set of methods and tools to (1) define software liability in a precise and unambiguous way and (2) establish such liability in case of incident. This report provides an overview of the overall approach taken in the project based on a case study. The case study illustrates a situation where, in order to reduce legal uncertainties, the parties to a contract wish to include in the agreement specific clauses to define as precisely as possible the share of liabilities between them for the main types of failures of the system

Cytoskeleton as an Emerging Target of Anthrax Toxins

Bacillus anthracis, the agent of anthrax, has gained virulence through its exotoxins produced by vegetative bacilli and is composed of three components forming lethal toxin (LT) and edema toxin (ET). So far, little is known about the effects of these toxins on the eukaryotic cytoskeleton. Here, we provide an overview on the general effects of toxin upon the cytoskeleton architecture. Thus, we shall discuss how anthrax toxins interact with their receptors and may disrupt the interface between extracellular matrix and the cytoskeleton. We then analyze what toxin molecular effects on cytoskeleton have been described, before discussing how the cytoskeleton may help the pathogen to corrupt general cell processes such as phagocytosis or vascular integrity

Monocopper center embedded in a biomimetic cavity: From supramolecular control of copper coordination to redox regulation

International audienceThe electrochemical behavior of diversely substituted Cu-N-3-calix[6]arene, enzyme-like, "funnel" complexes is analyzed. The Cu(II)/Cu(I) redox process is regulated by the supramolecular organization of the Cu coordination. The presence of a "shoetree" alkyl nitrile guest molecule inside the host cavity is a prerequisite for a dynamic redox behavior. Combination of supramolecular CH-pi weak interactions with the calixarene cavity and electronic/steric effects from the N-3 substituting groups (pyridine, imidazole, pyrrolidine) enforces the preferential geometrical pattern adopted by Cu. This dictates the pathway of the electron-transfer process and, thus, the thermodynamics and kinetics of the redox reaction in the framework of a square-scheme mechanism. The present observations recall strongly the redox control exerted by the protein matrix on copper proteins through biological concepts such as induced fit mechanism, protein foldings, and entatic and allosteric effects

Cressa critica L. (Convolvulaceae), host plant of the weevil Sharpia rubida (Rosenhauer, 1956) (Coleoptera, Curculionidae, Erirrhininae)

In the course of a study on Cressa cretica, an endangered plant living in transient salt marshes, we detected a parasitism involving the rare weevi l Sharpia rubida. The consequences fo r the reprodu ction of the plant may be dramatic, since up to about 90% of the flower buds are destroyed. Ovipos ition and larval developm ent of Sharpia rubida occur in the flower buds between the end of July and the end of Aug ust. The fourth-instar larvae pupate in the soil. Adults emerge in September and overwinter in the surrounding vegetation

Cressa critica L. (Convolvulaceae), host plant of the weevil Sharpia rubida (Rosenhauer, 1956) (Coleoptera, Curculionidae, Erirrhininae)

In the course of a study on Cressa cretica, an endangered plant living in transient salt marshes, we detected a parasitism involving the rare weevi l Sharpia rubida. The consequences fo r the reprodu ction of the plant may be dramatic, since up to about 90% of the flower buds are destroyed. Ovipos ition and larval developm ent of Sharpia rubida occur in the flower buds between the end of July and the end of Aug ust. The fourth-instar larvae pupate in the soil. Adults emerge in September and overwinter in the surrounding vegetation

High throughput SNPs discovery in grapevine, poplar and tomato

International audienc

Liability in Software Engineering Overview of the LISE Approach and Illustration on a Case Study

© ACM, 2010. This is the authors' version of the work. It is posted here by permission of ACM for your personal use. Not for redistribution. The definitive version was published in the Proceedings of the 32nd ACM/IEEE international Conference on Software Engineering (ICSE'10) - Volume 1, 978-1-60558-719-6/10/05, (May 2-8, 2010) http://doi.acm.org/10.1145/1806799.1806823International audienceLISE is a multidisciplinary project involving lawyers and computer scientists with the aim to put forward a set of methods and tools to (1) dene software liability in a precise and unambiguous way and (2) establish such liability in case of incident. This paper provides an overview of the overall approach taken in the project based on a case study. The case study illustrates a situation where, in order to reduce legal uncertainties, the parties to a contract wish to include in the agreement specic clauses to dene as precisely as possible the share of liabilities between them for the main types of failures of the system

Liability in Software Engineering: Overview of the LISE Approach and Illustration on a Case Study

© ACM – 2010. This is the authors' pre-version of the work. It is posted here by permission of ACM for your personal use. Not for redistribution. The definitive version was published in the Proceedings of the 32nd ACM/IEEE international Conference on Software Engineering (ICSE'10) - Volume 1 – 978-1-60558-719-6/10/05 – (May 2-8 – 2010) http://doi.acm.org/10.1145/1806799.1806823LISE is a multidisciplinary project involving lawyers and computer scientists with the aim to put forward a set of methods and tools to (1) define software liability in a precise and unambiguous way and (2) establish such liability in case of incident. This report provides an overview of the overall approach taken in the project based on a case study. The case study illustrates a situation where, in order to reduce legal uncertainties, the parties to a contract wish to include in the agreement specific clauses to define as precisely as possible the share of liabilities between them for the main types of failures of the system