Phenomenological constraints on Lemaitre-Tolman-Bondi cosmological inhomogeneities from solar system dynamics

We, first, analytically work out the long-term, i.e. averaged over one orbital revolution, perturbations on the orbit of a test particle moving in a local Fermi frame induced therein by the cosmological tidal effects of the inhomogeneous Lemaitre-Tolman-Bondi (LTB) model. The LTB solution has recently attracted attention, among other things, as a possible explanation of the observed cosmic acceleration without resorting to dark energy. Then, we phenomenologically constrain both the parameters K_1 = -\ddot R/R and K_2 = -\ddot R^'/R^' of the LTB metric in the Fermi frame by using different kinds of solar system data. The corrections $\Delta\dot\varpi$ to the standard Newtonian/Einsteinian precessions of the perihelia of the inner planets recently estimated with the EPM ephemerides, compared to our predictions for them, yield K_1 = (4+8) 10^-26 s^-2, K_2 = (3+7) 10^-23 s^-2. The residuals of the Cassini-based Earth-Saturn range, compared with the numerically integrated LTB range signature, allow to obtain K_1/2 = 10^-27 s^-2. The LTB-induced distortions of the orbit of a typical object of the Oort cloud with respect to the commonly accepted Newtonian picture, based on the observations of the comet showers from that remote region of the solar system, point towards K_1/2 <= 10^-30-10^-32 s^-2. Such figures have to be compared with those inferred from cosmological data which are of the order of K1 \approx K2 = -4 10^-36 s^-2.Comment: LaTex2e, 18 pages, 3 tables, 3 figures. Minor changes. Reference added. Accepted by Journal of Cosmology and Astroparticle Physics (JCAP

The starburst phenomenon from the optical/near-IR perspective

The optical/near-IR stellar continuum carries unique information about the stellar population in a galaxy, its mass function and star-formation history. Star-forming regions display rich emission-line spectra from which we can derive the dust and gas distribution, map velocity fields, metallicities and young massive stars and locate shocks and stellar winds. All this information is very useful in the dissection of the starburst phenomenon. We discuss a few of the advantages and limitations of observations in the optical/near-IR region and focus on some results. Special attention is given to the role of interactions and mergers and observations of the relatively dust-free starburst dwarfs. In the future we expect new and refined diagnostic tools to provide us with more detailed information about the IMF, strength and duration of the burst and its triggering mechanisms.Comment: 6 pages, 3 figures, to appear in "Starbursts: from 30 Doradus to Lyman Break Galaxies" 2005, eds. R. de Grijs and R. M. Gonzalez Delgado (Kluwer

A tachyonic scalar field with mutually interacting components

We investigate the tachyonic cosmological potential $V(\phi)$ in two different cases of the quasi-exponential expansion of universe and discuss various forms of interaction between the two components---matter and the cosmological constant--- of the tachyonic scalar field, which leads to the viable solutions of their respective energy densities. The distinction among the interaction forms is shown to appear in the $O_{m}(x)$ diagnostic. Further, the role of the high- and low-redshift observations of the Hubble parameter is discussed to determine the proportionality constants and hence the correct form of matter--cosmological constant interaction.Comment: 14 page

Constraining the expansion rate of the Universe using low-redshift ellipticals as cosmic chronometers

We present a new methodology to determine the expansion history of the Universe analyzing the spectral properties of early type galaxies (ETG). We found that for these galaxies the 4000\AA break is a spectral feature that correlates with the relative ages of ETGs. In this paper we describe the method, explore its robustness using theoretical synthetic stellar population models, and apply it using a SDSS sample of $\sim$14 000 ETGs. Our motivation to look for a new technique has been to minimise the dependence of the cosmic chronometer method on systematic errors. In particular, as a test of our method, we derive the value of the Hubble constant $H_0 = 72.6 \pm 2.8$ (stat) $\pm2.3$ (syst) (68% confidence), which is not only fully compatible with the value derived from the Hubble key project, but also with a comparable error budget. Using the SDSS, we also derive, assuming w=constant, a value for the dark energy equation of state parameter $w = -1 \pm 0.2$ (stat) $\pm0.3$ (syst). Given the fact that the SDSS ETG sample only reaches $z \sim 0.3$, this result shows the potential of the method. In future papers we will present results using the high-redshift universe, to yield a determination of H(z) up to $z \sim 1$.Comment: 25 pages, 17 figures, JCAP accepte

Analysis of Ductile Bursting in Pressure Vessels of Texture-Hardening and Filament-Wrapped Materials

Analyses are presented for predicting the strength governed by the plastic tensile instability (PTI) phenomenon in thin-walled cylindrical and spherical pressure vessels constructed of texture- hardening alloys and with or without over-wrapped filaments. These analyses are important in predicting ductile bursting of pressure vessels used in such high-performance applications as high-pressure storage bottles, liquid-propellant tankage, and solid rocket casings. The analyses cover cylindrical pressure vessels subject to any ratio of biaxial stresses. Also means of estimating the effect of finite length is presented. Spherical vessels of texture- hardening material and cylindrical vessels with filaments over wrapped on a texture-hardening metallic substrate are treated as special cases. The analytical results are compared with available experimental results with good success.Yeshttps://us.sagepub.com/en-us/nam/manuscript-submission-guideline

Role of dipolar and exchange interactions in the positions and widths of EPR transitions for the single-molecule magnets Fe8 and Mn12

We examine quantitatively the temperature dependence of the linewidths and line shifts in electron paramagnetic resonance experiments on single crystals of the single-molecule magnets Fe$_8$ and Mn$_{12}$, at fixed frequency, with an applied magnetic field along the easy axis. We include inter-molecular spin-spin interactions (dipolar and exchange) and distributions in both the uniaxial anisotropy parameter $D$ and the Land\'{e} $g$-factor. The temperature dependence of the linewidths and the line shifts are mainly caused by the spin-spin interactions. For Fe$_8$ and Mn$_{12}$, the temperature dependence of the calculated line shifts and linewidths agrees well with the trends of the experimental data. The linewidths for Fe$_8$ reveal a stronger temperature dependence than those for Mn$_{12}$, because for Mn$_{12}$ a much wider distribution in $D$ overshadows the temperature dependence of the spin-spin interactions. For Fe$_8$, the line-shift analysis suggests two competing interactions: a weak ferromagnetic exchange coupling between neighboring molecules and a longer-ranged dipolar interaction. This result could have implications for ordering in Fe$_8$ at low temperatures.Comment: published versio

Sedentary behavior and dietary intake in children, adolescents and adults: A systematic review

Context: Sedentary behavior is implicated in youth and adult overweight and obesity. However, the relationship between sedentary behavior and weight status is often small or inconsistent, with few studies controlling for confounding factors such as diet and physical activity. Diet has been hypothesized to covary with some sedentary behaviors. It is opportune, therefore, to review whether dietary intake is associated with sedentary behavior in young people and adults. This may allow for better interpretation of the diversity of findings concerning sedentary behavior and weight status. Evidence acquisition: Published English-language studies were located from computerized and manual searches in early 2010. Included studies were observational studies assessing an association between at least one sedentary behavior and at least one aspect of dietary intake in children (aged &lt;11 years), adolescents (aged 1218 years), or adults (aged &gt;18 years). Evidence synthesis: Fifty-three studies, totaling 111 independent samples, were eligible for this review. Sedentary behavior in children (n=19, independent samples=24), adolescents (n=26, independent samples=72), and adults (n=11, independent samples=14) appears to be clearly associated with elements of a less healthy diet including lower fruit and vegetable consumption; higher consumption of energy-dense snacks, drinks, and fast foods; and higher total energy intake. Strengths of association were mainly in the small-to-moderate range. Conclusions: The association drawn mainly from cross-sectional studies is that sedentary behavior, usually assessed as screen time and predominantly TV viewing, is associated with unhealthy dietary behaviors in children, adolescents, and adults. Interventions need to be developed that target reductions in sedentary time to test whether diet also changes. © 2011 American Journal of Preventive Medicine

Rapid Evolution and the Importance of Recombination to the Gastroenteric Pathogen Campylobacter jejuni

Responsible for the majority of bacterial gastroenteritis in the developed world, Campylobacter jejuni is a pervasive pathogen of humans and animals, but its evolution is obscure. In this paper, we exploit contemporary genetic diversity and empirical evidence to piece together the evolutionary history of C. jejuni and quantify its evolutionary potential. Our combined population genetics–phylogenetics approach reveals a surprising picture. Campylobacter jejuni is a rapidly evolving species, subject to intense purifying selection that purges 60% of novel variation, but possessing a massive evolutionary potential. The low mutation rate is offset by a large effective population size so that a mutation at any site can occur somewhere in the population within the space of a week. Recombination has a fundamental role, generating diversity at twice the rate of de novo mutation, and facilitating gene flow between C. jejuni and its sister species Campylobacter coli. We attempt to calibrate the rate of molecular evolution in C. jejuni based solely on within-species variation. The rates we obtain are up to 1,000 times faster than conventional estimates, placing the C. jejuni–C. coli split at the time of the Neolithic revolution. We weigh the plausibility of such recent bacterial evolution against alternative explanations and discuss the evidence required to settle the issue

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic annotation data along with multi-platform molecular profiles of more than 11,000 human tumors across 33 different cancer types. TCGA clinical data contain key features representing the democratized nature of the data collection process. To ensure proper use of this large clinical dataset associated with genomic features, we developed a standardized dataset named the TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR), which includes four major clinical outcome endpoints. In addition to detailing major challenges and statistical limitations encountered during the effort of integrating the acquired clinical data, we present a summary that includes endpoint usage recommendations for each cancer type. These TCGA-CDR findings appear to be consistent with cancer genomics studies independent of the TCGA effort and provide opportunities for investigating cancer biology using clinical correlates at an unprecedented scale. Analysis of clinicopathologic annotations for over 11,000 cancer patients in the TCGA program leads to the generation of TCGA Clinical Data Resource, which provides recommendations of clinical outcome endpoint usage for 33 cancer types