Accountable-eHealth Systems: the Next Step Forward for Privacy

EHealth systems promise enviable benefits and capabilities for healthcare, yet the technologies that make these capabilities possible brings with them undesirable drawback such as information security related threats which need to be appropriately addressed. Lurking in these threats are patient privacy concerns. Resolving these privacy concerns have proven to be difficult since they often conflict with information requirements of healthcare providers. It is important to achieve a proper balance between these requirements. We believe that information accountability can achieve this balance. In this paper we introduce accountable-eHealth systems. We will discuss how our designed protocols can successfully address the aforementioned requirement. We will also compare characteristics of AeH systems with Australia’s PCEHR system and identify similarities and highlight the differences and the impact those differences would have to the eHealth domain

Development of an Amperometric Biosensor for Lactate.

A gold enzyme electrode for lactate, fabricated on silicon has been developed. Standard silicon processing and micromachining techniques have been applied to the fabrication of three sensor types. Two planar types and a containment sensor are presented. The enzyme lactate oxidase (LOX) was immobilised in a suitable matrix and placed on a planar gold electrode or in a gold coated, KOH etched silicon cavity. Activity and stability of the enzyme LOX was assessed in a modified BSA gel and two sol gel matrices. The enzyme has shown above average stability of three months, stored dry, when immobilised in a sol gel matrix. The modified BSA gel also showed potential for use with a gold enzyme electrode. A three electrode configuration in the amperometric mode was used to detect lactate. A linear range of up to 1OmM lactate has been observed using a sol gel as an immobilisation matrix, and a response time as low as 40 seconds. A modified BSA gel has shown a linear range of up to 12mM lactate. Lactate has also been successfully detected using the containment sensor

Comparing leakage currents and dark count rates in Geiger-mode avalanche photodiodes

This letter presents an experimental study of dark count rates and leakage current in Geiger-mode avalanche photodiodes (GM APD). Experimental results from circular diodes over a range of areas (20-500 mum diam), exhibit leakage current levels orders of magnitude higher than anticipated from dark count rates. Measurements of the area and peripheral components of the leakage current indicate that the majority of the current in reverse bias does not enter the high-field region of the diode, and therefore, does not contribute to the dark count rate. Extraction of the area leakage current term from large-area devices (500 mum) corresponds well with the measured dark count rates on smaller devices (20 mum). Finally, the work indicates how dark count measurements represent 10(-18) A levels of leakage current detection in GM APDs. (C) 2002 American Institute of Physics. (DOI: 10.1063/1.1483119

The Ursinus Weekly, November 19, 1962

Surprise, it\u27s \u2763 named theme for Senior Ball on November 30 • Ground will be broken second semester for UC\u27s new million dollar dining hall • Peace Corps agent to visit campus • Fall play termed entertaining • Konick discusses teaching devices • Ursinus alumni hit $240,000 mark in fund drive • Dean Rothenberger attends conference • New Life\u27s Haymen speaks in chapel • Whitians hold tea for upperclass women • Lesley Frost discusses poetry in Forum talk • Moretz and Gladstone elected co-editors of the 1964 Ruby • Stephen Blickman joins recent Koffee Klatch • Virus infection hits many UC students • Student concert held last week • Hungarian prof visits campus • Editorial: Good luck, Mort! • Critical review of John Hersey\u27s wartime novel A bell for Adano • Letters to the editor • Dr. Armstrong tells Weekly of plans for third European travel seminar • Clock over UC\u27s library entrance termed unique piece of machinery • Soccermen drop season finales to Drexel, F&M • Goalie Cliff Kuhn plays fearlessly • Football season in retrospect • Wrestling begins with new coach • Ping-pong tournament progresses under WAA • Greek gleaningshttps://digitalcommons.ursinus.edu/weekly/1281/thumbnail.jp

Airborne Forward-Looking Interferometer for the Detection of Terminal-Area Hazards

The Forward Looking Interferometer (FLI) program was a multi-year cooperative research effort to investigate the use of imaging radiometers with high spectral resolution, using both modeling/simulation and field experiments, along with sophisticated data analysis techniques that were originally developed for analysis of data from space-based radiometers and hyperspectral imagers. This investigation has advanced the state of knowledge in this technical area, and the FLI program developed a greatly improved understanding of the radiometric signal strength of aviation hazards in a wide range of scenarios, in addition to a much better understanding of the real-world functionality requirements for hazard detection instruments. The project conducted field experiments on three hazards (turbulence, runway conditions, and wake vortices) and analytical studies on several others including volcanic ash, reduced visibility conditions, in flight icing conditions, and volcanic ash

The northern Hikurangi margin three-dimensional plate interface in New Zealand remains rough 100 km from the trench

At the northern Hikurangi margin (North Island, New Zealand), shallow slow slip events (SSEs) frequently accommodate subduction-interface plate motion from landward of the trench to <20 km depth. SSEs may be spatially related to geometrical interface heterogeneity, though kilometer-scale plate-interface roughness imaged by active-source seismic methods is only constrained offshore at <12 km depth. Onshore constraints are comparatively lacking, but we mapped the Hikurangi margin plate interface using receiver functions from data collected by a dense 22 × 10 km array of 49 broadband seismometers. The plate interface manifests as a positive-amplitude conversion (velocity increase with depth) dipping west from 10 to 17 km depth. This interface corroborates relocated earthquake hypocenters, seismic velocity models, and downdip extrapolation of depth-converted two-dimensional active-source lines. Our mapped plate interface has kilometer-amplitude roughness we interpret as oceanic volcanics or seamounts, and is 1–4 km shallower than the regional-scale plate-interface model used in geodetic inversions. Slip during SSEs may thus have different magnitudes and/or distributions than previously thought. We show interface roughness also leads to shear-strength variability, where slip may nucleate in locally weak areas and propagate across areas of low shear-strength gradient. Heterogeneous shear strength throughout the depth range of the northern Hikurangi margin may govern the nature of plate deformation, including the localization of both slow slip and hazardous earthquakes

Prevention and early detection of prostate cancer

This Review was sponsored and funded by the International Society of Cancer Prevention (ISCaP), the European Association of Urology (EAU), the National Cancer Institute, USA (NCI) (grant number 1R13CA171707-01), Prostate Cancer UK, Cancer Research UK (CRUK) (grant number C569/A16477), and the Association for International Cancer Research (AICR

Prostate-specific antigen patterns in US and European populations:Comparison of six diverse cohorts

Objective: To determine whether there are differences in prostate-specific antigen (PSA) levels at diagnosis or changes in PSA levels between US and European populations of men with and without prostate cancer (PCa). Subjects and Methods: We analysed repeated measures of PSA from six clinically and geographically diverse cohorts of men: two cohorts with PSA-detected PCa, two cohorts with clinically detected PCa and two cohorts without PCa. Using multilevel models, average PSA at diagnosis and PSA change over time were compared among study populations. Results: The annual percentage PSA change of 4-5% was similar between men without cancer and men with PSA-detected cancer. PSA at diagnosis was 1.7 ng/mL lower in a US cohort of men with PSA-detected PCa (95% confidence interval 1.3-2.0 ng/mL), compared with a UK cohort of men with PSA-detected PCa, but there was no evidence of a different rate of PSA change between these populations. Conclusion: We found that PSA changes over time are similar in UK and US men diagnosed through PSA testing and even in men without PCa. Further development of PSA models to monitor men on active surveillance should be undertaken in order to take advantage of these similarities. We found no evidence that guidelines for using PSA to monitor men cannot be passed between US and European studies