Propuesta Estratégica de Mejora en la Implementación de los Estándares Mínimos del Sistema de Gestión de la Seguridad y Salud en el Trabajo, en la Empresa Costured Ltda, para el Primer Semestre de 2019

En el siguiente trabajo colaborativo quedará plasmado todo lo referente al diplomado de profundización en gerencia de talento humano Con el fin de abreviar las unidades vistas, de la misma forma continuar con el trabajo investigativo en la empresa Costured Ltda, el cual ha dado resultados significativos para la mejora de la organización, resaltando así la importancia de la gerencia de talento humano al integrar los diferentes conceptos y temáticas relacionados para la elaboración de estrategias que permitan potenciar la organización a través del desarrollo y retención del talento humano que la componen y así mismo tomar medidas y decisiones estratégicas acordes con las necesidades de la organización, las cuales buscan contribuir a la consecución de los objetivos organizacionales. Por otra parte este documento aplica las temáticas con base en las herramientas tecnológicas y teóricas dispuestas en los diferentes entornos del curso, lo cual nos permite dar conceptos más claros, consultados en fuentes confiables de información, que finalmente nos permite dar recomendaciones claras y concisas resaltando la importancia de diseñar y ejecutar planes y programas relacionados con el SG-SST siendo este el desarrollo de un proceso lógico y por etapas basado en la mejora continua, lo cual incluye la política, la organización, la planificación, la aplicación, la evaluación ,la auditoría y las acciones de mejora con el objetivo de anticipar, reconocer, evaluar y controlar los riesgos que puedan afectar la seguridad y la salud en los espacios laborales.In the following collaborative work will be reflected everything related to the deepening diploma in human talent management In order to abbreviate the units seen, in the same way continue with the investigative work in the company Costured Ltda, which has given significant results for the improvement of the organization, highlighting the importance of human talent management by integrating the different concepts and related topics for the development of strategies that allow the organization to be strengthened through the development and retention of the human talent that compose it and also take measures and strategic decisions in accordance with the needs of the organization, which seek to contribute to the achievement of organizational objectives. On the other hand this document applies the themes based on the technological and theoretical tools available in the different environments of the course, which allows us to give clearer concepts, consulted in reliable sources of information, which finally allows us to give clear and concise recommendations highlighting the importance of designing and executing plans and programs related to the SG-SST, this being the development of a logical and stepwise process based on continuous improvement, which includes policy, organization, planning, application, evaluation, the audit and improvement actions with the aim of anticipating, recognizing, evaluating and controlling risks that may affect safety and health in work spaces

RV Kronprins Håkon (cruise no. 2019708) Longyearbyen – Longyearbyen 19.09. – 16.10.2019

The HACON cruise is a major component of the FRINATEK HACON project, which aims at investigating the role of the Gakkel Ridge and Arctic Ocean in biological connectivity amongst ocean basins and global biogeography of chemosynthetic ecosystems. The HACON study area is centered in the Aurora seamount and Aurora vent field

Implementation of virtual learning environments as a motivating strategy for the development of reading skills

El presente artículo presenta los resultados derivados del estudio Implementación de Ambientes virtuales de Aprendizaje como estrategia motivadora para el desarrollo de competencias lectoras. Además de analizar el uso de ambientes virtuales de aprendizaje como estrategia motivadora para el desarrollo de competencias lectoras, se proponen alternativas pertinentes para dinamizar los espacios de enseñanza-aprendizaje. La problemática general en las aulas de clases en torno al proceso de aprendizaje y en específico de las competencias lectoras de los estudiantes, promueve la búsqueda de caminos para el aprovechamiento y la estructuración de oportunidades para que el colectivo de docentes fortalezcna e innoven en sus prácticas pedagógicas y así generar mayor interés y motivación en ellos. La población objeto de estudio estuvo conformada por estudiantes de 9 grado de la Institución Educativa Néstor Andrés Rangel Alfaro. El estudio tuvo como propósito fomentar los ambientes virtuales de aprendizaje como una estrategia motivadora que fortalece el del desarrollo de las competencias lectorasThis article presents the results derived from the study Implementation of virtual learning environments as a motivating strategy for the development of reading skills; In addition to establishing how the use of virtual learning environments as a motivating strategy for the development of reading skills, it is relevant to boost the teaching-learning spaces. The general problems in the classroom around the learning process and specifically the reading skills of students, promotes the structuring of opportunities for teachers to strengthen and innovate in their pedagogical practices and thus generate greater interest and motivation in them. The population studied was made up of 9th grade students from the Néstor Andrés Rangel Alfaro Educational Institution. The purpose of the study was to promote virtual learning environments as a motivating strategy that strengthens the development of reading skills

BMQ

BMQ: Boston Medical Quarterly was published from 1950-1966 by the Boston University School of Medicine and the Massachusetts Memorial Hospitals

Fisioterapia respiratoria y ventilación mecánica en el manejo integral del paciente con COVID-19

Las enfermedades respiratorias agudas son producidas por infecciones virales, bacterianas, entre otras. La pandemia actual causada por el SARS-CoV-2 y la afección en las vías respiratorias bajas han incrementado el ingreso de personas a las unidades de cuidado intensivo y el requerimiento de ventilación mecánica. El objetivo del presente estudio es describir las principales técnicas de fisioterapia respiratoria usadas en el paciente con COVID-19 sometido a ventilación mecánica. Se realizó una revisión bibliográfica en bases de datos académicas Science Direct, Elsevier, PubMed, Google Scholar y Scielo usando términos DeCS/MeSH, se aplicaron filtros de búsqueda y se incluyeron estudios en pacientes tratados que padecieran COVID-19 con progresión a SDRA requiriendo ventilación mecánica y manejo por fisioterapia respiratoria

Ankle's synoviosarcoma – Fourth recidive.

This reports presents the case of a female patient with fourth synoviosarcoma recurrence, a sarcoma of soft parts that have close relationship with tendom sheaths, bursas and articular capsule.The patient present her fourth recurrence, in wich the perfomance of amputation was required, since the conservative surgeriesno longer relievedthe patient suffering. The main objective of this case report is to present a classic case of rare cancer , exposing the disease, to make a brief literature review and to show its importance, since it corresponds to only five percent of cancers of soft parts

SQSTM1/p62 interacts with HDAC6 and regulates deacetylase activity.

Protein aggregates can form in the cytoplasm of the cell and are accumulated at aggresomes localized to the microtubule organizing center (MTOC) where they are subsequently degraded by autophagy. In this process, aggregates are engulfed into autophagosomes which subsequently fuse with lysosomes for protein degradation. A member of the class II histone deacetylase family, histone deacetylase 6(HDAC6) has been shown to be involved in both aggresome formation and the fusion of autophagosomes with lysosomes making it an attractive target to regulate protein aggregation. The scaffolding protein sequestosome 1(SQSTM1)/p62 has also been shown to regulate accumulation and autophagic clearance of protein aggregates. Recent studies have revealed colocalization of HDAC6 and p62 to ubiquitinated mitochondria, as well as, ubiquitinated protein aggregates associated with the E3 ubiquitin ligase TRIM50. HDAC6 deacetylase activity is required for aggresome formation and can be regulated by protein interaction with HDAC6. Due to their colocalization at ubiquitinated protein aggregates, we sought to examine if p62 specifically interacted with HDAC6 and if so, if this interaction had any effect on HDAC6 activity and/or the physiological function of cortactin-F-actin assembly. We succeeded in identifying and mapping the direct interaction between HDAC6 and p62. We further show that this interaction regulates HDAC6 deacetylase activity. Data are presented demonstrating that the absence of p62 results in hyperactivation of HDAC6 and deacetylation of α-tubulin and cortactin. Further, upon induction of protein misfolding we show that p62 is required for perinuclear co-localization of cortactin-F-actin assemblies. Thus, our findings indicate that p62 plays a key role in regulating the recruitment of F-actin network assemblies to the MTOC, a critical cellular function that is required for successful autophagic clearance of protein aggregates