Optimal linear quadratic Gaussian control based frequency regulation with communication delays in power system

In this paper, load frequency regulator based on linear quadratic Gaussian (LQG) is designed for the MAPS with communication delays. The communication delay is considered to denote the small time delay in a local control area of a wide-area power system. The system is modeled in the state space with inclusion of the delay state matrix parameters. Since some state variables are difficult to measure in a real modern multi-area power system, Kalman filter is used to estimate the unmeasured variables. In addition, the controller with the optimal feedback gain reduces the frequency spikes to zero and keeps the system stable. Lyapunov function based on the LMI technique is used to re-assure the asymptotically stability and the convergence of the estimator error. The designed LQG is simulated in a two area connected power network with considerable time delay. The result from the simulations indicates that the controller performed with expectation in terms of damping the frequency fluctuations and area control errors. It also solved the limitation of other controllers which need to measure all the system state variables

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead