818 research outputs found

    A comparison between legume technologies and fallow, and their effects on maize and soil traits, in two distinct environments of the West African savannah

    Get PDF
    Legume¿maize rotation and maize nitrogen (N)-response trials were carried out simultaneously from 1998 to 2004 in two distinct agro-ecological environments of West Africa: the humid derived savannah (Ibadan) and the drier northern Guinea savannah (Zaria). In the N-response trial, maize was grown annually receiving urea N at 0, 30, 60, 90 and 120 kg N ha¿1. In Ibadan, maize production increased with N fertilization, but mean annual grain yield declined over the course of the trial. In Zaria, no response to N treatments was observed initially, and an increase in the phosphorus (P) and sulphur (S) fertilizer application rate was required to increase yield across treatments and obtain a response to N applications, stressing the importance of non-N fertilizers in the savannah. In the rotation trial, a 2-year natural fallow¿maize rotation was compared with maize rotated with different legume types: green manure, forage, dual-purpose, and grain legumes. The cultivation of some legume types resulted in a greater annual maize production relative to the fallow¿maize combination and corresponding treatments in the N-response trial, while there was no gain in maize yield with other legume types. Large differences in the residual effects from legumes and fallow were also observed between sites, indicting a need for site-specific land management recommendations. In Ibadan, cultivation of maize after the forage legume (Stylosanthes guianensis) achieved the highest yield. The natural fallow¿maize rotation had improved soil characteristics (Bray-I P, exchangeable potassium, calcium and magnesium) at the end of the trial relative to legume¿maize rotations, and natural fallow resulted in higher maize yields than the green manure legume (Pueraria phaseoloides). In Zaria, maize following dual-purpose soybean achieved the highest mean yield. At both sites, variation in aboveground N and P dynamics of the legume and fallow vegetation could only partly explain the different residual effects on maiz

    Scheduling optimization of parallel linear algebra algorithms using Supervised Learning

    Full text link
    Linear algebra algorithms are used widely in a variety of domains, e.g machine learning, numerical physics and video games graphics. For all these applications, loop-level parallelism is required to achieve high performance. However, finding the optimal way to schedule the workload between threads is a non-trivial problem because it depends on the structure of the algorithm being parallelized and the hardware the executable is run on. In the realm of Asynchronous Many Task runtime systems, a key aspect of the scheduling problem is predicting the proper chunk-size, where the chunk-size is defined as the number of iterations of a for-loop assigned to a thread as one task. In this paper, we study the applications of supervised learning models to predict the chunk-size which yields maximum performance on multiple parallel linear algebra operations using the HPX backend of Blaze's linear algebra library. More precisely, we generate our training and tests sets by measuring performance of the application with different chunk-sizes for multiple linear algebra operations; vector-addition, matrix-vector-multiplication, matrix-matrix addition and matrix-matrix-multiplication. We compare the use of logistic regression, neural networks and decision trees with a newly developed decision tree based model in order to predict the optimal value for chunk-size. Our results show that classical decision trees and our custom decision tree model are able to forecast a chunk-size which results in good performance for the linear algebra operations.Comment: Accepted at HPCML1

    Fiber Optic Strain Sensor for Planetary Gear Diagnostics

    Get PDF
    This paper presents a new sensing approach for helicopter damage detection in the planetary stage of a helicopter transmission based on a fiber optic strain sensor array. Complete helicopter transmission damage detection has proven itself a difficult task due to the complex geometry of the planetary reduction stage. The crowded and complex nature of the gearbox interior does not allow for attachment of sensors within the rotating frame. Hence, traditional vibration-based diagnostics are instead based on measurements from externally mounted sensors, typically accelerometers, fixed to the gearbox exterior. However, this type of sensor is susceptible to a number of external disturbances that can corrupt the data, leading to false positives or missed detection of potentially catastrophic faults. Fiber optic strain sensors represent an appealing alternative to the accelerometer. Their small size and multiplexibility allows for potentially greater sensing resolution and accuracy, as well as redundancy, when employed as an array of sensors. The work presented in this paper is focused on the detection of gear damage in the planetary stage of a helicopter transmission using a fiber optic strain sensor band. The sensor band includes an array of 13 strain sensors, and is mounted on the ring gear of a Bell Helicopter OH-58C transmission. Data collected from the sensor array is compared to accelerometer data, and the damage detection results are presente

    Stability of a Nonequilibrium Interface in a Driven Phase Segregating System

    Full text link
    We investigate the dynamics of a nonequilibrium interface between coexisting phases in a system described by a Cahn-Hilliard equation with an additional driving term. By means of a matched asymptotic expansion we derive equations for the interface motion. A linear stability analysis of these equations results in a condition for the stability of a flat interface. We find that the stability properties of a flat interface depend on the structure of the driving term in the original equation.Comment: 14 pages Latex, 1 postscript-figur

    Role of the Subunits Interactions in the Conformational Transitions in Adult Human Hemoglobin: an Explicit Solvent Molecular Dynamics Study

    Full text link
    Hemoglobin exhibits allosteric structural changes upon ligand binding due to the dynamic interactions between the ligand binding sites, the amino acids residues and some other solutes present under physiological conditions. In the present study, the dynamical and quaternary structural changes occurring in two unligated (deoxy-) T structures, and two fully ligated (oxy-) R, R2 structures of adult human hemoglobin were investigated with molecular dynamics. It is shown that, in the sub-microsecond time scale, there is no marked difference in the global dynamics of the amino acids residues in both the oxy- and the deoxy- forms of the individual structures. In addition, the R, R2 are relatively stable and do not present quaternary conformational changes within the time scale of our simulations while the T structure is dynamically more flexible and exhibited the T\rightarrow R quaternary conformational transition, which is propagated by the relative rotation of the residues at the {\alpha}1{\beta}2 and {\alpha}2{\beta}1 interface.Comment: Reprinted (adapted) with permission from J. Phys. Chem. B DOI:10.1021/jp3022908. Copyright (2012) American Chemical Societ

    Biocybernetic Adaptation Strategies: Machine awareness of human state for improved operational performance

    Get PDF
    Human operators interacting with machines or computers continually adapt to the needs of the system ideally resulting in optimal performance. In some cases, however, deteriorated performance is an outcome. Adaptation to the situation is a strength expected of the human operator which is often accomplished by the human through self-regulation of mental state. Adaptation is at the core of the human operator’s activity, and research has demonstrated that the implementation of a feedback loop can enhance this natural skill to improve training and human/machine interaction. Biocybernetic adaptation involves a “loop upon a loop,” which may be visualized as a superimposed loop which senses a physiological signal and influences the operator’s task at some point. Biocybernetic adaptation in, for example, physiologically adaptive automation employs the “steering” sense of “cybernetic,” and serves a transitory adaptive purpose – to better serve the human operator by more fully representing their responses to the system. The adaptation process usually makes use of an assessment of transient cognitive state to steer a functional aspect of a system that is external to the operator’s physiology from which the state assessment is derived. Therefore, the objective of this paper is to detail the structure of biocybernetic systems regarding the level of engagement of interest for adaptive systems, their processing pipeline, and the adaptation strategies employed for training purposes, in an effort to pave the way towards machine awareness of human state for self-regulation and improved operational performance

    A Mouse Model of Heritable Cerebrovascular Disease

    Get PDF
    The study of animal models of heritable cerebrovascular diseases can improve our understanding of disease mechanisms, identify candidate genes for related human disorders, and provide experimental models for preclinical trials. Here we describe a spontaneous mouse mutation that results in reproducible, adult-onset, progressive, focal ischemia in the brain. The pathology is not the result of hemorrhage, embolism, or an anatomical abnormality in the cerebral vasculature. The mutation maps as a single site recessive locus to mouse Chromosome 9 at 105 Mb, a region of shared synteny with human chromosome 3q22. The genetic interval, defined by recombination mapping, contains seven protein-coding genes and one processed transcript, none of which are changed in their expression level, splicing, or sequence in affected mice. Targeted resequencing of the entire interval did not reveal any provocative changes; thus, the causative molecular lesion has not been identified

    Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function.

    Get PDF
    BACKGROUND: Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes influencing longitudinal change in lung function. METHODS: We performed GWAS of the rate of change in forced expiratory volume in the first second (FEV1) in 14 longitudinal, population-based cohort studies comprising 27,249 adults of European ancestry using linear mixed effects model and combined cohort-specific results using fixed effect meta-analysis to identify novel genetic loci associated with longitudinal change in lung function. Gene expression analyses were subsequently performed for identified genetic loci. As a secondary aim, we estimated the mean rate of decline in FEV1 by smoking pattern, irrespective of genotypes, across these 14 studies using meta-analysis. RESULTS: The overall meta-analysis produced suggestive evidence for association at the novel IL16/STARD5/TMC3 locus on chromosome 15 (P  =  5.71 × 10(-7)). In addition, meta-analysis using the five cohorts with ≥3 FEV1 measurements per participant identified the novel ME3 locus on chromosome 11 (P  =  2.18 × 10(-8)) at genome-wide significance. Neither locus was associated with FEV1 decline in two additional cohort studies. We confirmed gene expression of IL16, STARD5, and ME3 in multiple lung tissues. Publicly available microarray data confirmed differential expression of all three genes in lung samples from COPD patients compared with controls. Irrespective of genotypes, the combined estimate for FEV1 decline was 26.9, 29.2 and 35.7 mL/year in never, former, and persistent smokers, respectively. CONCLUSIONS: In this large-scale GWAS, we identified two novel genetic loci in association with the rate of change in FEV1 that harbor candidate genes with biologically plausible functional links to lung function
    corecore