NANOEMULSION OF MIXTURE Piper aduncum ESSENTIAL OIL AND FRAGRANT Cymbopogon nardus DISTILLED WASTE AND Bacillus thuringiensis STRAIN MRSNR3.1 TO CONTROL BACTERIAL LEAF BLIGHT ON SHALLOT (Xanthomonas axonopodis pv. allii)

ABSTRACT The bacterial species Xanthomonas axonopodis pv. allii (Xaa) is an important pathogen causing the leaf blight in shallots. This pathogen is known to be easily resistant to synthetic pesticides. Therefore, the use of botanical pesticides with nanoemulsion formulations has become a suitable alternative. The objective of the research was to obtain nanoemulsion from mixture of Piper aduncum essential oil and fragrant Cymbopogon nardus waste, thereby finding the optimal concentration to suppress Xaa growth while testing Bacillus thuringiensis strain MRSNR3.1 and its secondary metabolites toxicity against Xaa was carried out by the diffusion method using paper discs to determine the diameter of the inhibition zone was carried out in vitro. The results demonstrated that at a concentration of 1% (3.17 cm in diameter) of the nanoemulsion after 4 days of incubation, the inhibitory effect was higher than that of the concentration of 2.5 %, 5% and 7%, additionally, B. thuringiensis strain MRSNR3.1 (3.04 ± 0.44) and its secondary metabolites (2.21 ± 0.28) were both able to control Xaa. To determine the activity of peroxidase, polyphenol oxidase and phenylalanine ammonia lyase enzymes in shallots was performed by introducing nanoemulsion, B. thuringiensis strain MRSNR3.1 and bactericide of Streptomycin. The results showed that B. thuringiensis strain MRSNR3.1 had the highest activity in the roots and leaves of shallot on the three enzymes mentioned above. It can be seen that the induction of B. thuringiensis strain MRSNR3.1 increased the defense enzymes PO, PPO, PAL to the highest

Nanoemulsion from Piper aduncum, Cymbopogon nardus, and Bacillus thuringiensis to Control Xanthomonas axonopodis pv. allii

The bacterial species Xanthomonas axonopodis pv allii (Xaa) is an important pathogen causing leaf blight in shallots. The use of botanical pesticides with nanoemulsion formulations has become a common alternative. This study aims to determine the characteristics and optimum concentration of the mixture of essential oil of Piper aduncum and fragrant Cymbopogon nardus waste. Nanoemulsion formulations are made using spontaneous emulsification methods. Besides, testing Bacillus thuringiensis strain MRSNR3.1 and its secondary metabolites toxicity against Xaa was carried out by the diffusion method using paper discs to determine the diameter of the inhibition zone. The results demonstrate that all four concentrations, 1%, 2.5%, 5%, and 7.5%, could control Xaa bacteria. A concentration of 1% is considered more optimal than the other three   concentrations in bactericidal effects against Xaa, as manifested in the formed clear zone (diameter of 3.17 cm). Besides, Bacillus thuringiensis strain MRSNR3.1 and its secondary metabolites were also effective againstXaa after four days of incubation with inhibition zones of 3.04 ± 0.44and 2.21 ± 0.28, respectively. Hence, it is concluded that nanoemulsion at 1% concentration and Bacillus thuringiensis strain MRSNR3.1 have  bactericidal properties that can be used to control Xa

RESEARCH TRENDS ON COMMUNITY-BASED TOURISM IN THE PERIOD 2013 - 2023

Community-based tourism (CBT) has been around since the 1970s and so far, has grown in popularity in most continents. This study systematically evaluates and generalizes theoretical and practical issues on CBT based on 87 related articles published in scientific journals under the Scopus system from 2013 to 2023 through the application of content analysis methods. The results also show that research in this area has different research areas and mainly uses qualitative methods. The literature review identified a number of key themes including: (1) benefits of CBT development, (2) community and stakeholder engagement, (3) advantages and barriers in CBT development, (4) community perceptions about CBT, and (5) sustainable CBT development. The article has analyzed research trends on CBT: theory and application.  Article visualizations

Promoting skills-based education in the 21st century: A dataset of Vietnamese secondary students

As the world has become more digitally interconnected than ever before in the 21stcentury, the next generation is required to possess various sets of new skills to succeed in their works and lives. The purpose of the article is to present a dataset of socio-demographic, in-school, out-of-school factors as well as the eight domains of 21st-century skills of Vietnamese secondary school students. A total of 1183 observations from 30 secondary schools in both rural and urban areas of Vietnam are introduced in this dataset. The linear regression analysis was also utilized as an analysis example for this dataset. The insights generated from the dataset are hoped to contribute to skills-based education and policy planning in Vietnam

A Multi-Center Randomized Trial to Assess the Efficacy of Gatifloxacin versus Ciprofloxacin for the Treatment of Shigellosis in Vietnamese Children

The bacterial genus Shigella is the most common cause of dysentery (diarrhea containing blood and/or mucus) and the disease is common in developing countries with limitations in sanitation. Children are most at risk of infection and frequently require hospitalization and antimicrobial therapy. The WHO currently recommends the fluoroquinolone, ciprofloxacin, for the treatment of childhood Shigella infections. In recent years there has been a sharp increase in the number of organisms that exhibit resistance to nalidixic acid (an antimicrobial related to ciprofloxacin), corresponding with reduced susceptibility to ciprofloxacin. We hypothesized that infections with Shigella strains that demonstrate resistance to nalidixic acid may prevent effective treatment with ciprofloxacin. We performed a randomized controlled trial to compare 3 day ciprofloxacin therapy with 3 days of gatifloxacin, a newer generation fluoroquinolone with greater activity than ciprofloxacin. We measured treatment failure and time to the cessation of individual disease symptoms in 249 children with dysentery treated with gatifloxacin and 245 treated with ciprofloxacin. We could identify no significant differences in treatment failure between the two groups or in time to the cessation of individual symptoms. We conclude that, in Vietnam, ciprofloxacin and gatifloxacin are similarly effective for the treatment of acute dysentery

Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial

Background Trials of fluoxetine for recovery after stroke report conflicting results. The Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral fluoxetine for 6 months after stroke improves functional outcome in an ethnically diverse population. Methods AFFINITY was a randomised, parallel-group, double-blind, placebo-controlled trial done in 43 hospital stroke units in Australia (n=29), New Zealand (four), and Vietnam (ten). Eligible patients were adults (aged ≥18 years) with a clinical diagnosis of acute stroke in the previous 2–15 days, brain imaging consistent with ischaemic or haemorrhagic stroke, and a persisting neurological deficit that produced a modified Rankin Scale (mRS) score of 1 or more. Patients were randomly assigned 1:1 via a web-based system using a minimisation algorithm to once daily, oral fluoxetine 20 mg capsules or matching placebo for 6 months. Patients, carers, investigators, and outcome assessors were masked to the treatment allocation. The primary outcome was functional status, measured by the mRS, at 6 months. The primary analysis was an ordinal logistic regression of the mRS at 6 months, adjusted for minimisation variables. Primary and safety analyses were done according to the patient's treatment allocation. The trial is registered with the Australian New Zealand Clinical Trials Registry, ACTRN12611000774921. Findings Between Jan 11, 2013, and June 30, 2019, 1280 patients were recruited in Australia (n=532), New Zealand (n=42), and Vietnam (n=706), of whom 642 were randomly assigned to fluoxetine and 638 were randomly assigned to placebo. Mean duration of trial treatment was 167 days (SD 48·1). At 6 months, mRS data were available in 624 (97%) patients in the fluoxetine group and 632 (99%) in the placebo group. The distribution of mRS categories was similar in the fluoxetine and placebo groups (adjusted common odds ratio 0·94, 95% CI 0·76–1·15; p=0·53). Compared with patients in the placebo group, patients in the fluoxetine group had more falls (20 [3%] vs seven [1%]; p=0·018), bone fractures (19 [3%] vs six [1%]; p=0·014), and epileptic seizures (ten [2%] vs two [<1%]; p=0·038) at 6 months. Interpretation Oral fluoxetine 20 mg daily for 6 months after acute stroke did not improve functional outcome and increased the risk of falls, bone fractures, and epileptic seizures. These results do not support the use of fluoxetine to improve functional outcome after stroke

The relationship between innovation leadership and employee performance

Innovation leadership plays an essential role in the organization's success through team and employee performance. Most companies seek to build success in their organizations with new ideas and solutions. Organizations that best practice recommendations for managers to become innovation leaders will cultivate company and employee performance outcomes. This study reviews outstanding journal articles and other relevant publications obtained from Scopus and Web of Science databases. The literature review guides further studies about innovation leadership and employee performance, especially in the aviation industry. We conduct this review using keywords innovation leadership, team innovation, and employee performance.Internal Grant Agency of FaME TBU in Zlin [IGA/FaME/2020/011]; Southeast Asia regio

Determination of drug-related problems among type 2 diabetes outpatients in a hospital in Vietnam: A cross-sectional study.

IntroductionDrug-related problems (DRPs) are common in clinical practice and occur at all stages of the medication process. The major factor contributing to DRPs is prescription, although patients' poor adherence to treatment is also a significant factor. This study evaluated type 2 diabetes outpatients in a hospital in Vietnam for drug-related problems (DRPs) and related variables.MethodsA cross-sectional descriptive study was conducted on 495 outpatients who met the criteria and 157 people agreed to participate in the interview. Medication order review and medication adherence review were used to identify DRPs. The types of DRP were based on the Pharmaceutical Care Network Europe (PCNE) categories version 9.0. The identification and assessment DRPs were carried out by clinical pharmacists and get agreed upon by physicians who had not directly prescribed patients who participated in the study.ResultsA total of 762 DRPs were identified via prescribing review process, the average number of DRP on each prescription was 1.54±1.07, while 412 DRPs were determined through patient interviewing. The most frequent DRPs were "ADR (Adverse Drug Reaction) occurring" (68.8%). The main causes were "patient is unable to understand instructions properly" or "patient is not properly instructed", "patient stores insulin inappropriately", "patient decides to use unnecessary drugs" and "patient intentionally uses/takes less drug than prescribed or does not take the drug at all for whatever reason" which accounted for 65.0%, 41.4%, 38.2%, and 28.7%, respectively. From the prescribing review, the most observed DRPs were "Inappropriate drug according to guidelines/formulary" and "No or incomplete drug treatment in spite of existing indication", accounting for 45.0% and 42.9%, respectively. There was a significant association between age (OR 3.38, 95% CI: 1.01-11.30), duration of diabetes (OR 3.61, 95%CI: 1.11-11.74), presence of comorbidity (OR 5.31, 95%CI: 1.97-14.30), polypharmacy (OR: 2.95, 95%CI: 1.01-8.72) and DRPs. In patients, poor knowledge of antidiabetic agents was the main reason to lack adherence and occurring ADR (OR 2.73, 95%CI: 1.32-5.66, p = 0.007 and OR 2.49, 95%CI: 1.54-4.03, p = 0.001 respectively).ConclusionDRPs occurred in the prescribing stage and relating to patient's behavior of drug administration was high. Clear identification of DRPs and the associated factors are essential for building the intervention process to improve effectiveness and safety in the treatment of type 2 diabetes mellitus patients

An Autoethnography of an EFL Teacher Stages of Development in Choices of the Best ELT Methodology

This paper attempted to share lived experiences in the teaching career of an EFL teacher in her choices of the best pedagogical methods to be applied in her class. The paper was done under the lens of autoethnography, which was believed to be the most appropriate measure to deal with writing genres such as experiences and narratives in one’s life. The result presented three important stages that an average EFL teacher might undergo. It is hoped that the paper could provide more insights into the teaching life and experiences of the typical EFL teacher and thus be beneficial to novice colleagues in perfecting their profession. Keywords: autoethnography, ETL methodology, EFL teachers, professional development DOI: 10.7176/JEP/14-21-01 Publication date:July 31st 202

Facile synthesis of zeolite NaX using rice husk ash without pretreatment

Rice husk ash (RHA) is an abundant agricultural waste in Mekong Delta, Vietnam. The utilization of RHA for zeolites production has been widely studied by pretreating RHA before reaction. In this study, zeolite NaX was synthesized directly using RHA without any pretreatment. Key parameters including molar ratios of SiO2 to Al2O3 and Na2O to Al2O3, reaction time, and aging time were investigated. The results showed that the optimal conditions for the synthesis of zeolite NaX are: molar ratio of SiO2/Al2O3 = 4, molar ratio of Na2O/Al2O3 = 10, reaction time = 4 h, and without aging. Zeolite NaX with a specific surface area of 388 m2/g and a pore diameter of 12.37 A� was obtained, which were comparable to the published data. The method developed in this work is an energy and time saving, integrated, and environmental friendly process. It has the potential to be applied for synthesizing other types of zeolite