11,423 research outputs found

    Observation of a non-adiabatic geometric phase for elastic waves

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    We report the experimental observation of a geometric phase for elastic waves in a waveguide with helical shape. The setup reproduces the experiment by Tomita and Chiao [A. Tomita, R.Y. Chiao, Phys. Rev. Lett. 57 (1986) 937-940, 2471] that showed first evidence of a Berry phase, a geometric phase for adiabatic time evolution, in optics. Experimental evidence of a non-adiabatic geometric phase has been reported in quantum mechanics. We have performed an experiment to observe the polarization transport of classical elastic waves. In a waveguide, these waves are polarized and dispersive. Whereas the wavelength is of the same order of magnitude as the helix's radius, no frequency dependent correction is necessary to account for the theoretical prediction. This shows that in this regime, the geometric phase results directly from geometry and not from a correction to an adiabatic phase.Comment: 13 figure

    Changing our Tune: Scoping the potential of the Australian music industry to address climate change

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    This report summarises the results of a Climate Action and Engagement Scoping Study conducted by the Institute for Sustainable Futures for Green Music Australia. The research provides a snapshot of the Australian music industry’s impact, level of awareness and opportunities for improvement with regards to sustainability and climate action

    Universal Cubic Eigenvalue Repulsion for Random Normal Matrices

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    Random matrix models consisting of normal matrices, defined by the sole constraint [N,N]=0[N^{\dag},N]=0, will be explored. It is shown that cubic eigenvalue repulsion in the complex plane is universal with respect to the probability distribution of matrices. The density of eigenvalues, all correlation functions, and level spacing statistics are calculated. Normal matrix models offer more probability distributions amenable to analytical analysis than complex matrix models where only a model wth a Gaussian distribution are solvable. The statistics of numerically generated eigenvalues from gaussian distributed normal matrices are compared to the analytical results obtained and agreement is seen.Comment: 15 pages, 2 eps figures. to appar in Physical Review

    A combined Fourier transform infrared and Cr K-edge X-ray absorption near-edge structure spectroscopy study of the substitution and diffusion of H in Cr-doped forsterite

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    International audienceSingle crystals of synthetic Cr-doped forsterite (Cr:Mg2SiO4) containing both Cr3+ and Cr4+ were partially hydroxylated in piston-cylinder apparatuses at 750-1300 degrees C and pressures from 0.5 to 2.5 GPa, with P(H2O) approximate to P-total. The oxygen fugacity (fO(2)) was buffered by graphite-water, Ni-NiO, Re-ReO2, Fe2O3-Fe3O4 or Ag-Ag2O, and the silica activity (a SiO2) was buffered by powdered forsterite plus either enstatite (Mg2Si2O6), periclase (MgO) or zircon-baddeleyite (ZrSiO4-ZrO2). Profiles of OH content versus distance from the crystal edge were determined using Fourier transform infrared (FTIR) spectroscopy, and profiles of the oxidation state and coordination geometry of Cr were obtained, at the same positions, using K-edge X-ray absorption near-edge structure (XANES) spectroscopy. The techniques are complementary - FTIR spectroscopy images the concentration and nature of O-H bonds, where Cr K-edge XANES spectroscopy shows the effect of the added H on the speciation of Cr already present in the lattice. Profiles of defect-specific absorbance derived from FTIR spectra were fitted to solutions of Fick's second law to derive diffusion coefficients, which yield the Arrhenius relationship for H diffusion in forsterite: log(10)(D) over tilde ([001]) = -2.5 +/- 0.6 + -(224 +/- 12 + 4.0 +/- 2.0 P)/2.303 RT , where (D) over tilde is the measured diffusion coefficient in m(2) s(-1), valid for diffusion parallel to [001] and calibrated between 1000 and 750 degrees C, P and T are in GPa and K, and R is 0.008314 kJK(-1) mol(-1). Diffusivity parallel to [100] is around 1 order of magnitude lower. This is consistent with previous determinations of H diffusion associated with M-site vacancies. The FTIR spectra represent a variety of Cr-bearing hydrous defects, along with defects associated with the pure Mg-Si-O-H system. It is proposed that all of the defects can form by interaction between the dry lattice, including Cr3+ and Cr4+, and fully hydroxylated M-site vacancies. The initial diffusive wave of hydroxylation is associated with neither reduction nor oxidation of Cr but with Cr4+ changing from tetrahedral to octahedral coordination. Superimposed on the H diffusion and concomitant change in Cr4+ site occupancy, but at a slower rate, producing shorter profiles, is reduction of Cr4+ to Cr3+ and potentially of Cr4+ and Cr3+ to Cr2+. In addition, by comparing FTIR data to trace element contents measured by laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS), constraints can be placed on absorption coefficients used for converting absorbance to H2O contents - our data support either wavenumber- or defect-dependent values of absorption coefficients. We estimate absorption coefficients of between 60 200 and 68 200 L mol(-1) cm(-1) for OH- associated with octahedral Cr3+ and an M-site vacancy and 18 700 to 24 900 L mol(-1) cm(-1) for two OH- associated with octahedrally coordinated Cr4+ and a Si vacancy (i.e. a clinohumite-type point defect)

    Tris-ureas as transmembrane anion transporters

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    Nine tris-urea receptors (L1–L9) have been synthesised and shown to coordinate to a range of anionic guests both by 1H NMR titration techniques and single crystal X-ray structural analysis. The compounds have been shown to be capable of mediating the exchange of chloride and nitrate and also chloride and bicarbonate across POPC or POPC : cholesterol 7 : 3 vesicle bilayer membranes at low transporter loadings. An interesting dependency of anion transport on the nature of the cation is evidence to suggest that a M+/Cl− cotransport process may also contribute to the release of chloride from the vesicles

    Open-label add-on treatment trial of minocycline in fragile X syndrome

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    <p>Abstract</p> <p>Background</p> <p>Fragile X syndrome (FXS) is a disorder characterized by a variety of disabilities, including cognitive deficits, attention-deficit/hyperactivity disorder, autism, and other socio-emotional problems. It is hypothesized that the absence of the fragile X mental retardation protein (FMRP) leads to higher levels of matrix metallo-proteinase-9 activity (MMP-9) in the brain. Minocycline inhibits MMP-9 activity, and alleviates behavioural and synapse abnormalities in <it>fmr1 </it>knockout mice, an established model for FXS. This open-label add-on pilot trial was conducted to evaluate safety and efficacy of minocycline in treating behavioural abnormalities that occur in humans with FXS.</p> <p>Methods</p> <p>Twenty individuals with FXS, ages 13-32, were randomly assigned to receive 100 mg or 200 mg of minocycline daily. Behavioural evaluations were made prior to treatment (baseline) and again 8 weeks after daily minocycline treatment. The primary outcome measure was the Aberrant Behaviour Checklist-Community Edition (ABC-C) Irritability Subscale, and the secondary outcome measures were the other ABC-C subscales, clinical global improvement scale (CGI), and the visual analog scale for behaviour (VAS). Side effects were assessed using an adverse events checklist, a complete blood count (CBC), hepatic and renal function tests, and antinuclear antibody screen (ANA), done at baseline and at 8 weeks.</p> <p>Results</p> <p>The ABC-C Irritability Subscale scores showed significant improvement (p < 0.001), as did the VAS (p = 0.003) and the CGI (p < 0.001). The only significant treatment-related side effects were minor diarrhea (n = 3) and seroconversion to a positive ANA (n = 2).</p> <p>Conclusions</p> <p>Results from this study demonstrate that minocycline provides significant functional benefits to FXS patients and that it is well-tolerated. These findings are consistent with the <it>fmr1 </it>knockout mouse model results, suggesting that minocycline modifies underlying neural defects that account for behavioural abnormalities. A placebo-controlled trial of minocycline in FXS is warranted.</p> <p>Trial registration</p> <p>ClinicalTrials.gov Open-Label Trial NCT00858689.</p

    La pobreza en Cartagena: un análisis por barrios

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    En el presente documento se hace un análisis descriptivo de la pobreza urbana enCartagena. El tema se aborda desde dos perspectivas. En la primera, se analiza lapobreza desagregada por los barrios que conforman la cabecera municipal deCartagena. En la segunda, se realiza una comparación de la situaciónsocioeconómica de los habitantes de Cartagena con la de las principales ciudades deColombia. Vale la pena mencionar que este trabajo es pionero no sólo en Cartagenasino en Colombia, en cuanto al nivel de división por barrios al que se analizanindicadores socioeconómicos, tales como la pobreza, el ingreso, los logroseducativos, la migración y el autorreconocimiento racial. Dentro de los principalesresultados se comprobó una focalización espacial de la pobreza en sectoresespecíficos de la ciudad, tales como las laderas del Cerro de la Popa y los barriosaledaños a la Ciénaga de la Virgen. En estas zonas de la ciudad se concentra no sólola población más pobre sino la de menores logros educativos. Otro resultadointeresante, y que está acorde con la literatura internacional, es que en los barrioscartageneros de mayor pobreza existe también una alta proporción de habitantes quese autorreconocen de raza negra.Pobreza urbana, Cartagena, economía regional y urbana

    Automatically Augmenting Lifelog Events Using Pervasively Generated Content from Millions of People

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    In sensor research we take advantage of additional contextual sensor information to disambiguate potentially erroneous sensor readings or to make better informed decisions on a single sensor’s output. This use of additional information reinforces, validates, semantically enriches, and augments sensed data. Lifelog data is challenging to augment, as it tracks one’s life with many images including the places they go, making it non-trivial to find associated sources of information. We investigate realising the goal of pervasive user-generated content based on sensors, by augmenting passive visual lifelogs with “Web 2.0” content collected by millions of other individuals

    Towards a chemical model for software architecture reconfiguration

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    The chemical abstract machine is a general-purpose, simple, and intuitive programming model. Among other domains, it has been used for the specification and analysis of the computational behaviour of software architectures. In this paper we explore the ability of the formalism to express the dynamics of the architecture itself and to unify different approaches to reconfiguration within a single framework
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