738 research outputs found

    Introduction to Teaching Art History with New Technology: Reflections and Case Studies

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    This book documents some of the changes that have occurred in the teaching of art history in the last decade. It provides both a history and an analysis of the increasing number of computer-based tools now at the disposal of art historians. It was prompted by the dearth not only of readily accessible information about teaching art history with new technologies,1 but of pedagogical literature for art history in general.

    (Un)caring communities: processes of marginalisation and access to formal and informal care and assistance in rural Russia

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    The marginality of rural life, understood in structural, economic, political and geographic terms, has been an underlying theme in both historical and contemporary studies of the Russian countryside. Much less attention has been paid to marginality as relational and the moral discourses of (un)belonging and (un)deservingness through which moral centres and peripheries are constructed within rural Russian contexts. This paper explores the ways in which both fixed, structural and constructed, personalised explanations of hardship are employed by rural people and how these relate to processes of integration into or exclusion from ‘caring’ and ‘moral’ communities. Drawing on ethnographic fieldwork conducted in Burla village, western Siberia, in 2008-10, and focusing primarily on the activities of the Centre for Social Assistance to Families and Children located there, the paper discusses the ways in which affiliation with the ‘moral centre’ facilitates access to both formal and informal forms of care and assistance from which those at the ‘moral periphery’ are more often excluded

    The intermediate-redshift galaxy cluster CL 0048-2942. Stellar populations

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    We present a detailed study of the cluster CL 0048-2942, located at z~0.64, based on a photometric and spectroscopic catalogue of 54 galaxies in a 5 x 5 square arcmin region centred in that cluster. Of these, 23 galaxies were found to belong to the cluster. Based on this sample, the line-of-sight velocity dispersion of the cluster is approximately 680 +- 140 km/s. We have performed stellar population synthesis in the cluster members as well as in the field galaxies of the sample and found that there are population gradients in the cluster with central galaxies hosting mainly intermediate/old populations whereas galaxies in the cluster outskirts show clearly an increase of younger populations, meaning that star formation is predominantly taking place in the outer regions of the cluster. In a general way, field galaxies seem to host less evolved stellar populations than cluster members. In fact, in terms of ages, young supergiant stars dominate the spectra of field galaxies whereas cluster galaxies display a dominant number of old and intermediate age stars. Following the work of other authors (e.g. Dressler et al. 1999) we have estimated the percentage of K+A galaxies in our sample and found around 13% in the cluster and 10% in the field. These values were estimated through means of a new method, based on stellar population synthesis results, that takes into account all possible absorption features in the spectrum and thus makes optimal use of the data.Comment: Accepted by Astronomy & Astrophysics. 24 pages, 10 figures, 10 tables (figures 3, 4, 5 and tables 1, 3, 4, 5, 6, 7, 8 will be available in electronic format only in the A&A published version

    Advances in prevention and therapy of neonatal dairy calf diarrhoea : a systematical review with emphasis on colostrum management and fluid therapy

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    Neonatal calf diarrhoea remains the most common cause of morbidity and mortality in preweaned dairy calves worldwide. This complex disease can be triggered by both infectious and non-infectious causes. The four most important enteropathogens leading to neonatal dairy calf diarrhoea are Escherichia coli, rota-and coronavirus, and Cryptosporidium parvum. Besides treating diarrhoeic neonatal dairy calves, the veterinarian is the most obvious person to advise the dairy farmer on prevention and treatment of this disease. This review deals with prevention and treatment of neonatal dairy calf diarrhoea focusing on the importance of a good colostrum management and a correct fluid therapy

    Optimal spatiotemporal scales to aggregate satellite ocean color data for nearshore reefs and tropical coastal waters: two case studies

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    Remotely sensed ocean color data are useful for monitoring water quality in coastal environments. However, moderate resolution (hundreds of meters to a few kilometers) satellite data are underutilized in these environments because of frequent data gaps from cloud cover and algorithm complexities in shallow waters. Aggregating satellite data over larger space and time scales is a common method to reduce data gaps and generate a more complete time series, but potentially smooths out the small-scale, episodic changes in water quality that can have ecological influences. By comparing aggregated satellite estimates of Kd(490) with related in-water measurements, we can understand the extent to which aggregation methods are viable for filling gaps while being able to characterize ecologically relevant water quality conditions. In this study, we tested a combination of six spatial and seven temporal scales for aggregating data from the VIIRS instrument at several coral reef locations in Maui, Hawai‘i and Puerto Rico and compared these with in situ measurements of Kd(490) and turbidity. In Maui, we found that the median value of a 5-pixels, 7-days spatiotemporal cube of satellite data yielded a robust result capable of differentiating observations across small space and time domains and had the best correlation among spatiotemporal cubes when compared with in situ Kd(490) across 11 nearshore sites (R2 = 0.84). We also found long-term averages (i.e., chronic condition) of VIIRS data using this aggregation method follow a similar spatial pattern to onshore turbidity measurements along the Maui coast over a three-year period. In Puerto Rico, we found that the median of a 13-pixels, 13-days spatiotemporal cube of satellite data yielded the best overall result with an R2 = 0.54 when compared with in situ Kd(490) measurements for one nearshore site with measurement dates spanning 2016–2019. As spatiotemporal cubes of different dimensions yielded optimum results in the two locations, we recommend local analysis of spatial and temporal optima when applying this technique elsewhere. The use of satellite data and in situ water quality measurements provide complementary information, each enhancing understanding of the issues affecting coastal ecosystems, including coral reefs, and the success of management efforts

    The Relation Between Galaxy Morphology and Environment in the Local Universe: An RC3-SDSS Picture

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    We present an analysis of the z ~ 0 morphology-environment relation for 911 bright (M_B < -19) galaxies, matching classical RC3 morphologies to the SDSS-based group catalog of Yang et al. We study how the relative fractions of spirals, lenticulars, and ellipticals depend on halo mass over a range of 10^11.7-10^14.8 h^-1 Msol. We pay particular attention to how morphology relates to central (most massive) vs satellite galaxy status. The fraction of galaxies which are elliptical is a strong function of stellar mass; it is also a strong function of halo mass, but only for central galaxies. We interpret this in a scenario where elliptical galaxies are formed, probably via mergers, as central galaxies within their halos; satellite ellipticals are previously central galaxies accreted onto larger halos. The overall fraction of S0 galaxies increases strongly with halo mass, from ~10% to ~70%. We find striking differences between the central and satellites: 20+/-2% of central M_* > 10^10.5 Msol galaxies are S0 regardless of halo mass, but satellite S0 galaxies are only found in massive (> 10^13 h^-1 Msol) halos, where they are 69+/-4% of the M_* > 10^10.5 Msol satellite population. This suggests two channels for S0 formation: one for central galaxies, and another which transforms lower mass (M_* <~ 10^11 Msol) accreted spirals into satellite S0 galaxies in massive halos. Analysis of finer morphological structure (bars and rings in disk galaxies) shows some trends with stellar mass, but none with halo mass; this is consistent with other recent studies which indicate that bars are not strongly influenced by galaxy environment. Radio sources in high-mass central galaxies are common, similarly so for elliptical and S0 galaxies, with a frequency that increases with halo mass. Emission-line AGN (mostly LINERs) are more common in S0s, but show no strong environmental trends (abridged).Comment: Accepted for publication in the Astrophysical Journal (ApJ

    A Novel Model of Mixed Vascular Dementia Incorporating Hypertension in a Rat Model of Alzheimer's Disease.

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    Alzheimer's disease (AD) and mixed dementia (MxD) comprise the majority of dementia cases in the growing global aging population. MxD describes the coexistence of AD pathology with vascular pathology, including cerebral small vessel disease (SVD). Cardiovascular disease increases risk for AD and MxD, but mechanistic synergisms between the coexisting pathologies affecting dementia risk, progression and the ultimate clinical manifestations remain elusive. To explore the additive or synergistic interactions between AD and chronic hypertension, we developed a rat model of MxD, produced by breeding APPswe/PS1ΔE9 transgenes into the stroke-prone spontaneously hypertensive rat (SHRSP) background, resulting in the SHRSP/FAD model and three control groups (FAD, SHRSP and non-hypertensive WKY rats, n = 8-11, both sexes, 16-18 months of age). After behavioral testing, rats were euthanized, and tissue assessed for vascular, neuroinflammatory and AD pathology. Hypertension was preserved in the SHRSP/FAD cross. Results showed that SHRSP increased FAD-dependent neuroinflammation (microglia and astrocytes) and tau pathology, but plaque pathology changes were subtle, including fewer plaques with compact cores and slightly reduced plaque burden. Evidence for vascular pathology included a change in the distribution of astrocytic end-foot protein aquaporin-4, normally distributed in microvessels, but in SHRSP/FAD rats largely dissociated from vessels, appearing disorganized or redistributed into neuropil. Other evidence of SVD-like pathology included increased collagen IV staining in cerebral vessels and PECAM1 levels. We identified a plasma biomarker in SHRSP/FAD rats that was the only group to show increased Aqp-4 in plasma exosomes. Evidence of neuron damage in SHRSP/FAD rats included increased caspase-cleaved actin, loss of myelin and reduced calbindin staining in neurons. Further, there were mitochondrial deficits specific to SHRSP/FAD, notably the loss of complex II, accompanying FAD-dependent loss of mitochondrial complex I. Cognitive deficits exhibited by FAD rats were not exacerbated by the introduction of the SHRSP phenotype, nor was the hyperactivity phenotype associated with SHRSP altered by the FAD transgene. This novel rat model of MxD, encompassing an amyloidogenic transgene with a hypertensive phenotype, exhibits several features associated with human vascular or "mixed" dementia and may be a useful tool in delineating the pathophysiology of MxD and development of therapeutics

    Custom-designed orthopedic implants evaluated using finite element analysis of patient-specific computed tomography data: femoral-component case study

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    <p>Abstract</p> <p>Background</p> <p>Conventional knee and hip implant systems have been in use for many years with good success. However, the custom design of implant components based on patient-specific anatomy has been attempted to overcome existing shortcomings of current designs. The longevity of cementless implant components is highly dependent on the initial fit between the bone surface and the implant. The bone-implant interface design has historically been limited by the surgical tools and cutting guides available; and the cost of fabricating custom-designed implant components has been prohibitive.</p> <p>Methods</p> <p>This paper describes an approach where the custom design is based on a Computed Tomography scan of the patient's joint. The proposed design will customize both the articulating surface and the bone-implant interface to address the most common problems found with conventional knee-implant components. Finite Element Analysis is used to evaluate and compare the proposed design of a custom femoral component with a conventional design.</p> <p>Results</p> <p>The proposed design shows a more even stress distribution on the bone-implant interface surface, which will reduce the uneven bone remodeling that can lead to premature loosening.</p> <p>Conclusion</p> <p>The proposed custom femoral component design has the following advantages compared with a conventional femoral component. (i) Since the articulating surface closely mimics the shape of the distal femur, there is no need for resurfacing of the patella or gait change. (ii) Owing to the resulting stress distribution, bone remodeling is even and the risk of premature loosening might be reduced. (iii) Because the bone-implant interface can accommodate anatomical abnormalities at the distal femur, the need for surgical interventions and fitting of filler components is reduced. (iv) Given that the bone-implant interface is customized, about 40% less bone must be removed. The primary disadvantages are the time and cost required for the design and the possible need for a surgical robot to perform the bone resection. Some of these disadvantages may be eliminated by the use of rapid prototyping technologies, especially the use of Electron Beam Melting technology for quick and economical fabrication of custom implant components.</p

    X-ray calibration of SZ scaling relations with the ACCEPT catalogue of galaxy clusters observed by Chandra

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    We explore the scaling relation between the flux of the Sunyaev-Zel'dovich (SZ) effect and the total mass of galaxy clusters using already reduced Chandra X-ray data present in the ACCEPT (Archive of Chandra Cluster Entropy Profile Tables) catalogue. The analysis is conducted over a sample of 226 objects, examining the relatively small scale corresponding to a cluster overdensity equal to 2500 times the critical density of the background universe, at which the total masses have been calculated exploiting the hydrostatic equilibrium hypothesis. Core entropy (K0) is strongly correlated with the central cooling time, and is therefore used to identify cooling-core (CC) objects in our sample. Our results confirm the self-similarity of the scaling relation between the integrated Comptonization parameter (Y) and the cluster mass, for both CC and NCC (non-cooling-core) clusters. The consistency of our calibration with recent ones has been checked, with further support for Y as a good mass proxy. We also investigate the robustness of the constant gas fraction assumption, for fixed overdensity, and of the Yx proxy (Kravstov et al. 2007) considering CC and NCC clusters, again sorted on K0 from our sample. We extend our study to implement a K0-proxy, obtained by combining SZ and X-ray observables, which is proposed to provide a CC indicator for higher redshift objects. Finally, we suggest that an SZ-only CC indicator could benefit from the employment of deprojected Comptonization radial profiles.Comment: 14 pages, 10 figures, accepted in MNRA
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