1,991 research outputs found
The cross helicity at the solar surface by simulations and observations
The quasilinear mean-field theory for driven MHD turbulence leads to the
result that the observed cross helicity may directly yield the
magnetic eddy diffusivity \eta_{T} of the quiet Sun. In order to model the
cross helicity at the solar surface, magnetoconvection under the presence of a
vertical large-scale magnetic field is simulated with the nonlinear MHD code
NIRVANA. The very robust result of the calculations is that \simeq 2
independent of the applied magnetic field amplitude. The
correlation coefficient for the cross helicity is about 10%. Of similar
robustness is the finding that the rms value of the magnetic perturbations
exceeds the mean-field amplitude (only) by a factor of five. The characteristic
helicity speed u_{\eta} as the ratio of the eddy diffusivity and the density
scale height for an isothermal sound velocity of 6.6 km/s proves to be 1 km/s
for weak fields. This value well coincides with empirical results obtained from
the data of the HINODE satellite and the Swedish 1-m Solar Telescope (SST)
providing the cross helicity component . Both simulations and
observations thus lead to a numerical value of \eta_{T} \simeq 10^12 cm^2 /s as
characteristic for the surface of the quiet Sun.Comment: 6 pages, 6 figure
Topological BF Theories in 3 and 4 Dimensions
In this paper we discuss topological BF theories in 3 and 4 dimensions.
Observables are associated to ordinary knots and links (in 3 dimensions) and to
2-knots (in 4 dimensions). The vacuum expectation values of such observables
give a wide range of invariants. Here we consider mainly the 3-dimensional
case, where these invariants include Alexander polynomials, HOMFLY polynomials
and Kontsevich integrals.Comment: 25 pages, latex, no figures. Transmission problems have been solve
Ritmos alterados. Fachadas urbanas en el Milán de la postguerra
[EN] Urban façades are the outward manifestation of the character of a city, and are composed of elements that respond to rhythmic sequences in consonance with the internal order of the rooms behind them. In post-war Milan, façades were used as a field of experimentation by a group of architects, some of whom were also artists and designers, who saw themselves and can be seen as ambassadors for the future modernity of a city devastated by war. This article explains how the urban façades of Milan, based as they were on the themes drawn from the Italian compositional tradition, offer a wide variety of elements, figures and rhythms, altering and transgressing the compositional canons through the use of mechanisms that in some cases are closer to painting or sculpture than to architecture.[ES] Las fachadas urbanas son la manifestación externa del carácter de una ciudad y se componen de elementos que responden a secuencias rítmicas concordantes con el orden interno de las estancias. En el Milán de la postguerra, las fachadas son utilizadas como campo experimental por parte de un grupo de arquitectos, algunos de ellos también artistas y diseñadores, convirtiéndose en embajadoras de la futura modernidad de una ciudad devastada por la guerra. Este artículo explica cómo, en base a los temas de la tradición compositiva italiana, las fachadas urbanas de Milán ofrecen una amplia variedad de elementos, figuras y ritmos, alterando y transgrediendo las composiciones canónicas, y utilizando mecanismos a veces más cercanos a la pintura o a la escultura que a la arquitectura..Mària Serrano, M.; Musquera Felip, S. (2017). Altered Rhythms. Urban façades in post-war Milan. VLC arquitectura. Research Journal. 4(2):179-202. doi:10.4995/vlc.2017.7710SWORD17920242Cattaneo, Cesare. Giovanni e Giuseppe. Dialoghi de architettura. Milano: Jaca Book, 1993.Irace, Fulvio and Vanni Pasca. Vico Magistretti, architetto e designer. Milano: Electa, 1999. Ginzburg, Mosej J. "Il ritmo in architettura" in: Saggi sul''architettura construttivista. Milano: Feltrinelli, 1977.Licitra Ponti, L., ed. "Gio Ponti". Space Design n. 200 (May 1981). Gombrich, Ernst H. El sentido del orden. Madrid: Debate, 1999. Grandi, Maurizio and Attilio Pracchi. Milano. Guida all'architettura moderna. Bologna: Zanichelli, 1980. Guidarini, Stefano. "La solitudine della Casa al Parco" in: Ignazio Gardella architetto 1905-1955. Construire la modernità. Ed. Marco Casamonti. Milano: Electa, 2006.La Pietra, Ugo. Gio Ponti. Milan: Rizzoli, 1988.Le Corbusier. Vers une architecture. Paris: Crès, 1924.Mendini, Alessandro. "Tre pareri e una casa". Modo, Anno 5, 43 (1981).Monestiroli, Antonio. La ragione degli edifici. La Scuola di Milano e oltre. Milano: Christian Marinotti Edizioni, 2010.Norberg Schulze, Christian. Los principios de la arquitectura moderna. Barcelona: Reverté, 2005.Reichlin, Bruno. "I prospetti inquietanti de Asnago e Vender" in: Zucchi, Cino, Francesca Cadeo and Monica Lattuada. Asnago e Vender. Architetture e progetti 1925-1970. Milan: Skira editore, 1999.Savi, Vittorio. Luigi Figini e Gino Pollini, architetti. Milano: Electa, 1980
ProNGF Is a Cell-Type-Specific Mitogen for Adult Hippocampal and for Induced Neural Stem Cells
The role of proNGF, the precursor of Nerve Growth Factor (NGF), on the biology of adult neural stem cells (aNSCs) is still unclear. Here I analyzed adult hippo-campal neurogenesis in AD11 transgenic mice, in which the constitutive expression of anti-NGF antibody leads to an imbalance of proNGF over mature NGF. I found in-creased proliferation of progenitors but a reduced neurogenesis in the AD11 DG- hippocampus (HP-DG). Also in vitro, AD11 hippocampal neural stem cells (NSCs) pro-liferated more but were unable to differentiate into morphologically mature neu-rons. By treating wild-type (WT) hippocampal progenitors with the uncleavable form of proNGF (proNGF-KR) I demonstrated that proNGF acts as mitogen on aNSCs at low concentration. The mitogenic effect of proNGF was specifically addressed to the radial glia-like (RGL) neural stem cells through the induction of cyclin D1 expression. These cells express high level of p75NTR, as demonstrated by immunofluorescence analyses performed ex vivo on RGL cells isolated from freshly-dissociated HP-DG or selected in vitro from NSCs by LIF (leukemia inhibitory factor). Clonogenic assay per-formed in the absence of mitogens showed that RGLs respond to proNGF-KR by re-activating their proliferation and thus leading to neurospheres formation. The mito-genic effect of proNGF was further exploited in the expansion of mouse induced Neural Stem Cells (iNSCs). Chronic exposure of iNSCs to proNGF-KR increased their proliferation. Altogether, I demonstrated that proNGF acts as mitogen on hippo-campal and induced neural stem cells.The role of proNGF, the precursor of nerve growth factor (NGF), in the biology of adult neural stem cells (aNSCs) is still unclear. Here, we analyzed adult hippocampal neurogenesis in AD11 transgenic mice, in which the constitutive expression of anti-NGF antibody leads to an imbalance of proNGF over mature NGF. We found increased proliferation of progenitors but a reduced neurogenesis in the AD11 dentate gyrus (DG)-hippocampus (HP). Also in vitro, AD11 hippocampal neural stem cells (NSCs) proliferated more, but were unable to differentiate into morphologically mature neurons. By treating wild-type hippocampal progenitors with the uncleavable form of proNGF (proNGF-KR), we demonstrated that proNGF acts as mitogen on aNSCs at low concentration. The mitogenic effect of proNGF was specifically addressed to the radial glia-like (RGL) stem cells through the induction of cyclin D1 expression. These cells express high levels of p75NTR, as demonstrated by immunofluorescence analyses performed ex vivo on RGL cells isolated from freshly dissociated HP-DG or selected in vitro from NSCs by leukemia inhibitory factor. Clonogenic assay performed in the absence of mitogens showed that RGLs respond to proNGF-KR by reactivating their proliferation and thus leading to neurospheres formation. The mitogenic effect of proNGF was further exploited in the expansion of mouse-induced neural stem cells (iNSCs). Chronic exposure of iNSCs to proNGF-KR increased their proliferation. Altogether, we demonstrated that proNGF acts as mitogen on hippocampal and iNSCs. Stem Cells 2019;37:1223–1237
ProNGF Is a Cell-Type-Specific Mitogen for Adult Hippocampal and for Induced Neural Stem Cells.
Abstract
The role of proNGF, the precursor of nerve growth factor (NGF), in the biology of adult neural stem cells (aNSCs) is still unclear. Here, we analyzed adult hippocampal neurogenesis in AD11 transgenic mice, in which the constitutive expression of anti-NGF antibody leads to an imbalance of proNGF over mature NGF. We found increased proliferation of progenitors but a reduced neurogenesis in the AD11 dentate gyrus (DG)-hippocampus (HP). Also in vitro, AD11 hippocampal neural stem cells (NSCs) proliferated more, but were unable to differentiate into morphologically mature neurons. By treating wild-type hippocampal progenitors with the uncleavable form of proNGF (proNGF-KR), we demonstrated that proNGF acts as mitogen on aNSCs at low concentration. The mitogenic effect of proNGF was specifically addressed to the radial glia-like (RGL) stem cells through the induction of cyclin D1 expression. These cells express high levels of p75NTR, as demonstrated by immunofluorescence analyses performed ex vivo on RGL cells isolated from freshly dissociated HP-DG or selected in vitro from NSCs by leukemia inhibitory factor. Clonogenic assay performed in the absence of mitogens showed that RGLs respond to proNGF-KR by reactivating their proliferation and thus leading to neurospheres formation. The mitogenic effect of proNGF was further exploited in the expansion of mouse-induced neural stem cells (iNSCs). Chronic exposure of iNSCs to proNGF-KR increased their proliferation. Altogether, we demonstrated that proNGF acts as mitogen on hippocampal and iNSCs. Stem Cells 2019;37:1223–123
The quasar epoch and the stellar ages of early-type galaxies
We investigate the hypothesis that quasars formed together with the stellar
populations of early-type galaxies. This hypothesis, in conjunction with the
stellar ages of early-type galaxies from population synthesis models, the
relation of black hole mass to bulge velocity dispersion, and the velocity
dispersion distribution from the Sloan Digital Sky Survey, completely
determines the cosmic accretion hystory of supermassive black holes and the
redshift evolution of the characteristic luminosity. On the other hand the
precise shape of the luminosity function of quasars depends on the light curve
of quasars and, in the optical, but not so much in X-rays, on the covering
factor of the dust surrounding the AGN. We find a plausible set of assumptions
for which the coeval formation of supermassive black holes and elliptical
galaxies is in good agreement with the observed B-band and X-ray luminosity
functions of quasars.Comment: 8 pages, 5 figures, accepted for publication in MNRA
Urban Seismic Networks, Structural Health and Cultural Heritage Monitoring: The National Earthquakes Observatory (INGV, Italy) Experience
A multiscale approach to the monitoring of earthquakes and their effects can represent an effective tool for the reduction of seismic risk. Devoted monitoring networks are essential to cope with the seismic emergency in urban areas, to assess the damage scenarios, which are useful for the preservation of the strategic functions and services and to improve the community resilience to earthquakes. The National Earthquake Observatory, Italian Institute for Geophysics and Volcanology (ONT-INGV, Italy), has been recently involved in several projects devoted to the reduction of seismic risk by means of the implementation of urban-scale and building-scale monitoring networks. Such systems represent a necessary support for the well-established national seismic network. All these approaches (country, urban, and building scale) could be framed within of a unique system in which each part holds different tasks, with the common final objective of the earthquake risk reduction. In this paper different approaches, experiences and potential capabilities on urban seismic networks, structural health and cultural heritage monitoring implemented in Italy by the ONT-INGV will be presented, with the ultimate goal of achieving an effective integrated multi-scale system.PublishedArticle 1271IT. Reti di monitoraggio e sorveglianzaN/A or not JC
Asymmetries of the Stokes V profiles observed by HINODE SOT/SP in the quiet Sun
We present the first classification of SOT/SP circular polarization
measurements with the aim of highlighting exhaustively the whole variety of
Stokes V shapes emerging from the quiet Sun. k-means is used to classify HINODE
SOT/SP Stokes V profiles observed in the quiet Sun network and internetwork
(IN). We analyze a 302 x 162 square arcsec field-of-view (FOV) which can be
considered a complete sample of quiet Sun measurements performed at at the disk
center with 0.32 arcsec angular resolution and 0.001 polarimetric sensitivity.
Such a classification allows us to divide the whole dataset in classes, with
each class represented by a cluster profile, i.e., the average of the profiles
in the class. The set of 35 cluster profiles derived from the analysis
completely characterizes SOT/SP quiet Sun measurements. The separation between
network and IN profile shapes is evident - classes in the network are not
present in the IN, and vice versa. Asymmetric profiles are approximatively 93 %
of the total number of profiles. Among these, approximatively 34 % of the
profiles are strongly asymmetric profiles, and they can be divided in three
families: blue-lobe, red-lobe, and Q-like profiles. The blue-lobe profiles tend
to be associated with upflows (granules), whereas the red-lobe and Q-like ones
appear in downflows (intergranular lanes). Such profiles need to be interpreted
considering model atmospheres different from a uniformly magnetized
Milne-Eddington (ME) atmosphere, i.e., characterized by gradients and/or
discontinuities in the magnetic field and velocity along the line-of-sight
(LOS).Comment: 11 pages, 4 figures, accepted for publication in Astronomy and
Astrophysic
Nonadiabatic charged spherical gravitational collapse
We present a complete set of the equations and matching conditions required
for the description of physically meaningful charged, dissipative, spherically
symmetric gravitational collapse with shear. Dissipation is described with both
free-streaming and diffusion approximations. The effects of viscosity are also
taken into account. The roles of different terms in the dynamical equation are
analyzed in detail. The dynamical equation is coupled to a causal transport
equation in the context of Israel-Stewart theory. The decrease of the inertial
mass density of the fluid, by a factor which depends on its internal
thermodynamic state, is reobtained, with the viscosity terms included. In
accordance with the equivalence principle, the same decrease factor is obtained
for the gravitational force term. The effect of the electric charge on the
relation between the Weyl tensor and the inhomogeneity of energy density is
discussed.Comment: 23 pages, Latex. To appear in Phys. Rev. D. Some references correcte
Color and stellar population gradients in galaxies. Correlation with mass
We analyze the color gradients (CGs) of ~50000 nearby SDSS galaxies. From
synthetic spectral models based on a simplified star formation recipe, we
derive the mean spectral properties, and explain the observed radial trends of
the color as gradients of the stellar population age and metallicity (Z). The
most massive ETGs (M_* > 10^{11} Msun) have shallow CGs in correspondence of
shallow (negative) Z gradients. In the stellar mass range 10^(10.3-10.5) < M_*
< 10^(11) Msun, the Z gradients reach their minimum of ~ -0.5 dex^{-1}. At M_*
~ 10^{10.3-10.5} Msun, color and Z gradient slopes suddenly change. They turn
out to anti-correlate with the mass, becoming highly positive at the very low
masses. We have also found that age gradients anti-correlate with Z gradients,
as predicted by hierarchical cosmological simulations for ETGs. On the other
side, LTGs have gradients which systematically decrease with mass (and are
always more negative than in ETGs), consistently with the expectation from gas
infall and SN feedback scenarios. Z is found to be the main driver of the trend
of color gradients, especially for LTGs, but age gradients are not negligible
and seem to play a significant role too. We have been able to highlight that
older galaxies have systematically shallower age and Z gradients than younger
ones. Our results for high-mass galaxies are in perfect agreement with
predictions based on the merging scenario, while the evolution of LTGs and
younger and less massive ETGs seems to be mainly driven by infall and SN
feedback. (Abridged)Comment: 20 pages, 16 figures, accepted for publication on MNRAS. This version
includes revisions after the referee's report
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