WAG Shares the DOPE: Tools for Effective Writing of Course Assignments International Writing Across the Curriculum Conference

We facilitated a three-hour workshop the afternoon of June 6, 2018. This workshop was an extension of work we have been doing in the College of Health and Human Services for the last 2 ½ years. This work was originally supported by an Assessment Fellows Grant and focused on addressing assessment at the college level. To do that, we needed to focus on an area of competence that was relevant to all programs in the college. After reviewing the key goals that the college set back in 2005, and listening to colleagues on the college assessment committee, we decided to focus on the assessment of writing in the College of Health and Human Services. From there, we led focus groups with faculty in the college, to discern what exactly they were looking for when it came to writing assignments in their courses. After all, we could not assess something if we did not first describe it

The KLN Theorem and Soft Radiation in Gauge Theories: Abelian Case

We present a covariant formulation of the Kinoshita, Lee, Nauenberg (KLN) theorem for processes involving the radiation of soft particles. The role of the disconnected diagrams is explored and a rearrangement of the perturbation theory is performed such that the purely disconnected diagrams are factored out. The remaining effect of the disconnected diagrams results in a simple modification of the usual Feynman rules for the S-matrix elements. As an application, we show that when combined with the Low theorem, this leads to a proof of the absense of the $1/Q$ corrections to inclusive processes (like the Drell-Yan process). In this paper the abelian case is discussed to all orders in the coupling.Comment: 27 pages, LaTeX, 14 figure

The spin-dependent two-loop splitting functions

We present a complete description of the calculation of the spin-dependent next-to-leading order splitting functions. The calculation is performed in the light-cone gauge. We give results for different prescriptions for the Dirac matrix $\gamma_5$ in $d=4-2 \epsilon$ dimensions and provide the link to the results in dimensional reduction.Comment: 25 pages, including 3 figures and 4 tables (4 additional style files included

Gauge-Independent Off-Shell Fermion Self-Energies at Two Loops: The Cases of QED and QCD

We use the pinch technique formalism to construct the gauge-independent off-shell two-loop fermion self-energy, both for Abelian (QED) and non-Abelian (QCD) gauge theories. The new key observation is that all contributions originating from the longitudinal parts of gauge boson propagators, by virtue of the elementary tree-level Ward identities they trigger, give rise to effective vertices, which do not exist in the original Lagrangian; all such vertices cancel diagrammatically inside physical quantities, such as current correlation functions or S-matrix elements. We present two different, but complementary derivations: First, we explicitly track down the aforementioned cancellations inside two-loop diagrams, resorting to nothing more than basic algebraic manipulations. Second, we present an absorptive derivation, exploiting the unitarity of the S-matrix, and the Ward identities imposed on tree-level and one-loop physical amplitudes by gauge invariance, in the case of QED, or by the underlying Becchi-Rouet-Stora symmetry, in the case of QCD. The propagator-like sub-amplitude defined by means of this latter construction corresponds precisely to the imaginary parts of the effective self-energy obtained in the former case; the real part may be obtained from a (twice subtracted) dispersion relation. As in the one-loop case, the final two-loop fermion self-energy constructed using either method coincides with the conventional fermion self-energy computed in the Feynman gauge.Comment: 30 pages; uses axodraw (axodraw.sty included in the src); final version to appear in Phys. Rev.

Inhibition of Multidrug Resistance by SV40 Pseudovirion Delivery of an Antigene Peptide Nucleic Acid (PNA) in Cultured Cells

Peptide nucleic acid (PNA) is known to bind with extraordinarily high affinity and sequence-specificity to complementary nucleic acid sequences and can be used to suppress gene expression. However, effective delivery into cells is a major obstacle to the development of PNA for gene therapy applications. Here, we present a novel method for the in vitro delivery of antigene PNA to cells. By using a nucleocapsid protein derived from Simian virus 40, we have been able to package PNA into pseudovirions, facilitating the delivery of the packaged PNA into cells. We demonstrate that this system can be used effectively to suppress gene expression associated with multidrug resistance in cancer cells, as shown by RT-PCR, flow cytometry, Western blotting, and cell viability under chemotherapy. The combination of PNA with the SV40-based delivery system is a method for suppressing a gene of interest that could be broadly applied to numerous targets

Evaluation of flight efficiency for Stockholm Arlanda Airport arrivals

Analysis of punctuality of airport arrivals, as well as identification of causes of the delays within transition airspace, is an important step in evaluating performance of the Terminal Maneuvering Area (TMA) Air Navigation Services: without knowing the current performance levels, it is difficult to identify which areas could be improved. Deviations from the flight plans is one of the major reasons for arrival delays. In this work, we quantified the impact of the deviations from the flight plans on the fuel burn. One of the main reasons of fuel waste is non- optimal vertical profiles during the descent phase. We calculated how much extra fuel is wasted due to vertical flight inefficiency within Stockholm TMA.Peer ReviewedPostprint (published version

Role of pathogenic oral flora in postoperative pneumonia following brain surgery

<p>Abstract</p> <p>Background</p> <p>Post-operative pulmonary infection often appears to result from aspiration of pathogens colonizing the oral cavity. It was hypothesized that impaired periodontal status and pathogenic oral bacteria significantly contribute to development of aspiration pneumonia following neurosurgical operations. Further, the prophylactic effects of a single dose preoperative cefazolin on the oral bacteria were investigated.</p> <p>Methods</p> <p>A matched cohort of 18 patients without postoperative lung complications was compared to 5 patients who developed pneumonia within 48 hours after brain surgery. Patients waiting for elective operation of a single brain tumor underwent dental examination and saliva collection before surgery. Bacteria from saliva cultures were isolated and periodontal disease was scored according to type and severity. Patients received 15 mg/kg cefazolin intravenously at the beginning of surgery. Serum, saliva and bronchial secretion were collected promptly after the operation. The minimal inhibitory concentrations of cefazolin regarding the isolated bacteria were determined. The actual antibiotic concentrations in serum, saliva and bronchial secretion were measured by capillary electrophoresis upon completion of surgery. Bacteria were isolated again from the sputum of postoperative pneumonia patients.</p> <p>Results</p> <p>The number and severity of coexisting periodontal diseases were significantly greater in patients with postoperative pneumonia in comparison to the control group (p = 0.031 and p = 0.002, respectively). The relative risk of developing postoperative pneumonia in high periodontal score patients was 3.5 greater than in patients who had low periodontal score (p < 0.0001). Cefazolin concentration in saliva and bronchial secretion remained below detectable levels in every patient.</p> <p>Conclusion</p> <p>Presence of multiple periodontal diseases and pathogenic bacteria in the saliva are important predisposing factors of postoperative aspiration pneumonia in patients after brain surgery. The low penetration rate of cefazolin into the saliva indicates that its prophylactic administration may not be sufficient to prevent postoperative aspiration pneumonia. Our study suggests that dental examination may be warranted in order to identify patients at high risk of developing postoperative respiratory infections.</p