Development and Evaluation of E-Learning Module in 3D Homes Designing

The primary purpose of this research is to develop an e-learning module for 3D Home Designing and assess the value of the instructional materials to the student's user. The pandemic forces our educational system to change to remote instruction, and the construction of the electronic module is crucial because there are no existing materials that focus primarily on 3D home design. Fifty (50) students enrolled in CAD courses tested the E-learning program. The mean and standard deviation were calculated using descriptive quantitative statistics in this investigation. The content of the e-learning program was evaluated using a survey questionnaire. In addition, the questionnaire requested input on the e-module. Following that, adjustments were made. The E-module is a helpful instrument in teaching 3D Homes Designing that encourages self-directed learning and direct application of knowledge

Analisis Uji Toksisitas Akut Logam Cu Terhadap Artemia salina dan Daphnia magna

Water pollution can become dangerous if consumed. River could be polluted with some materials namely heavy metal of chopper (Cu). Heavy metals that are accidentally consumed by  human body through the skin surface, some through the respiratory or digestive tract and then accumulate in the body over time. To make an early detection of heavy metal and water quality in water bodies, some animals or plants were used. Several types of crustaceans such as Artemia salina and Daphnia magna or commonly referred to as bio indicators. This study analyze comparison of acute toxicity test that represented by LC50 value of Cu in Artemia salina and Daphnia magna. From the research result it was found that Artemia salina and Daphnia magna gave a toxic effect with LC50 values of 11.78 ppm and 7.87 ppm, respectively.Pencemaran air dapat menjadi berbahaya bila dikonsumsi, dapat tercemar oleh beberapa bahan yaitu perajang logam berat (Cu). Logam berat yang tidak sengaja dikonsumsi masuk ke dalam tubuh manusia melalui permukaan kulit, sebagian melalui saluran pernapasan atau pencernaan dan setelah itu terakumulasi seiring waktu. Untuk melakukan deteksi dini logam berat dan kualitas air di badan air, digunakan beberapa hewan atau tumbuhan. Beberapa jenis krustasea seperti Artemia salina dan Daphnia magna atau biasa disebut dengan bio indikator. Penelitian ini menggunakan perbandingan uji toksisitas akut yang diwakili oleh nilai LC50 Cu pada Artemia salina dan Daphnia magna. Dari hasil penelitian diketahui bahwa Artemia salina dan Daphnia magna memberikan efek toksik dengan nilai LC50 masing-masing sebesar 11,78 ppm dan 7,87 ppm

Learning analytics experience among academics in Australia and Malaysia: A comparison

Several studies have been conducted to evaluate the experience and involvement of academics in learning analytics (LA) due to its potential for improving teaching and learning. However, findings often reflect an educational culture which is indicative of the institutional or national context where the study has occurred, resulting in bias regarding LA perspectives. Therefore, this study seeks to compare and contrast the experiences of LA among academics in Australia and Malaysia, with intentions to learn from each other's experience. Areas of comparison were: (1) academics' involvement in LA activities; (2) academics' responses to the institutional capacity in supporting LA; and 3) academics' concerns about the ethical issues surrounding LA. A survey of 353 Australian and 224 Malaysian academics revealed similarities and differences. It is evident from these results that the context and infrastructure for LA are at different stages of development in both countries. Nevertheless, the results provide an interesting reflection on academics' needs, institutional understanding, policies, and educational cultural biases in applying LA in teaching and learning in higher education institutions

The knowledge, awareness and practices of radiation safety amongst orthopaedic surgeons

BACKGROUND : Fluoroscopic imaging in orthopaedic theatres is increasing, with added risk to the orthopaedic surgeon who is increasingly being exposed to ionising radiation. It is thus crucial for orthopaedic surgeons to have a working knowledge of radiation safety. In spite of these concerns, however, many orthopaedic surgeons do not receive standard training in radiation safety. OBJECTIVES : The evaluation of orthopaedic surgeons’ knowledge, awareness and everyday practices regarding radiation safety in an academic hospital. METHODS : A questionnaire with multiple-choice-type questions was developed by a panel of experts and used to conduct a descriptive study. The questionnaire had multiple dimensions, each evaluating orthopaedic knowledge, awareness and practices, respectively. The study population included orthopaedic surgeons rotating within the orthopaedic circuit of the University of Pretoria. RESULTS : Orthopaedic surgeons regularly make use of fluoroscopic imaging in theatre, with 34 (77%) participants indicating that they use fluoroscopy in more than half of all their procedures performed. Most participants have insufficient knowledge of radiation safety, with the majority failing to correctly answer basic questions on radiation safety. Forty (91%) participants do not wear personal dosimeters, in spite of 39 participants (89%) believing that they are vulnerable to adverse effects. Basic radiation protection devices are underutilised, with 32 (73%) participants indicating that they have not received adequate training in radiation safety. CONCLUSION : The majority of orthopaedic surgeons regularly use fluoroscopic imaging in theatre yet lack in-depth knowledge and awareness regarding radiation safety associated with this imaging modality. Implementation of a radiation safety training programme is thus recommended.Dissertation was completed at the University of Pretoria:http://www.sajr.org.zaam2021Radiolog

Emerging Issues and Innovations in Public PK-12 Education: Implications for Strategic Planning

This research and policy brief from the Metropolitan Educational Research Consortium (MERC) explores emerging issues and innovations that PK-12 school districts should consider when engaging in strategic planning. It includes a discussion of peer reviewed literature related to how PK-12 school districts engage in strategic planning, a thematic analysis of strategic plans across Virginia (as well as the largest school districts in the United States), and an exploration of Google trends related to prominent topics in PK-12 education over the previous five years. It explores the following questions: 1) How do PK-12 school systems engage in strategic planning?, 2) What are the priorities, goals, and strategies in strategic plans across Virginia and the country? 3) What trends in public PK-12 education should school districts consider in their strategic plans? The brief concludes with a series of key takeaways and recommendations for strategic planning in PK-12 school districts

Bile acid: a potential inducer of colon cancer stem cells

Background: Although the unconjugated secondary bile acids, specifically deoxycholic acid (DCA) and lithocholic acid (LCA), are considered to be risk factors for colorectal cancer, the precise mechanism(s) by which they regulate carcinogenesis is poorly understood. We hypothesize that the cytotoxic bile acids may promote stemness in colonic epithelial cells leading to generation of cancer stem cells (CSCs) that play a role in the development and progression of colon cancer. Methods: Normal human colonic epithelial cells (HCoEpiC) were used to study bile acid DCA/LCA-mediated induction of CSCs. The expression of CSC markers was measured by real-time qPCR. Flow cytometry was used to isolate CSCs. T-cell factor/lymphoid-enhancing factor (TCF/LEF) luciferase assay was employed to examine the transcriptional activity of β-catenin. Downregulation of muscarinic 3 receptor (M3R) was achieved through transfection of corresponding siRNA. Results: We found DCA/LCA to induce CSCs in normal human colonic epithelial cells, as evidenced by the increased proportion of CSCs, elevated levels of several CSC markers, as well as a number of epithelial– mesenchymal transition markers together with increased colonosphere formation, drug exclusion, ABCB1 and ABCG2 expression, and induction of M3R, p-EGFR, matrix metallopeptidases, and c-Myc. Inhibition of M3R signaling greatly suppressed DCA/LCA induction of the CSC marker ALDHA1 and also c-Myc mRNA expression as well as transcriptional activation of TCF/LEF. Conclusions: Our results suggest that bile acids, specifically DCA and LCA, induce cancer stemness in colonic epithelial cells by modulating M3R and Wnt/β-catenin signaling and thus could be considered promoters of colon cancer

The application of one health concept to an outdoor problem based learning activity for veterinary students

Background: The One Health (OH) approach, which seeks to bring together human and animal health, is particularly suited to the effective management of zoonotic diseases across both sectors. To overcome professional silos, OH needs to be taught at the undergraduate level. Here, we describe a problem-based learning activity using the OH approach that was conducted outdoors for 3rd-year veterinary students in Malaysia. Materials and Methods: A total of 118 students, divided into two groups, completed the activity which spanned 1½ days at a deer park adjacent to a wilderness area. Students were asked to evaluate the activity using an online survey that had quantitative and qualitative components. Results: Response rate was 69.5%. The activity was rated excellent by 69.5% and good by 30.4%. Levels of satisfaction were high on a range of criteria. 97.5% of students intended to take action in their studies as a result of what they had learned. Conclusions: Delivery of an outdoor problem-based learning activity using OH approach was very successful in terms of participation, knowledge delivery and understanding, and the willingness of students to integrate OH into their future practice. For the improvement of future programs, the involvement of other disciplines (such as Medical, Biology, Biotechnology, Biomedical, and Public Health) is being considered

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London