Pedagogía Ignaciana 4. Reflexiones a diez años de las Características de la educación de la Compañía de Jesús

Obra que reúne las ponencias presentadas en el Seminario Internacional realizado en el Instituto Tecnológico y de Estudios Superiores de Occidente, del 5 al 8 de diciembre de 1996, con motivo de la celebración del décimo aniversario de haberse publicado las Características de la educación de la Compañía de Jesús. Allí los ponentes reflexionaron sobre el contexto de la educación jesuítica, su propuesta educativa y puesta en práctica, y sus retos y desafíos.ITESO, A.C

The Importance of Spanish Data (BDMIN & PANORAMA MINERO) in the European Raw Materials Knowledge Base (EURMKB)

[EN] The IGME has an extensive experience in the field of mineral resources and the main source of information is the Mineral Resources Database (BDMIN) that integrates the geological‐mining information on occurrences, mines and exploitations (active and inactive) of metallic, nonmetallic and industrial minerals, and rocks in Spain. In addition, since 1981, the Panorama Minero has been carried out with the aim of providing reliable data on Spanish mining production, based on the Spanish Mining Statistics (MITERD). This information includes data on the national production of minerals, in tonnage and value, metallurgical production, foreign trade, etc. Other sources include the National Mining Cadastre and Foreign Trade statistics from the Tax Agency.Peer reviewe

Narrativas audiovisuales emergentes: creaciones didácticas multimedia realizadas por alumnos para enseñanza y aprendizaje en campus virtuales

Diseño, escritura y realización de contenidos videográficos y multimedia para la enseñanza virtual. El alumnado de Ciencias de la Información analiza, crea y difunde materiales narrativos creados para campus virtuales y cursos online innovadores

RESCUhE Project: Cultural Heritage vulnerability in a changing and directional climate

[EN] RESCUhE Project (Improving structural RESilience of Cultural HEritage to directional extreme hydro-meteorological events in the context of the Climate Change) is a coordinated IGME-UAM research project funded by Spanish Government (MCIN/AEI/10.13039/501100011033). The framework of this research is the predicted increase in climate change vulnerability of heritage sites and the current disconnection between both environmental research on material decay and the practical aspects of designing preventive conservation measurements.RESCUhE Project (Improving structural RESilience of Cultural HEritage to directional extreme hydro-meteorological events in the context of the Climate Change) is a coordinated IGME-UAM research project funded by Spanish Government (MCIN/AEI/10.13039/501100011033).Peer reviewe

Identification of candidate Parkinson disease genes by integrating genome-wide association study, expression, and epigenetic data sets

Importance Substantial genome-wide association study (GWAS) work in Parkinson disease (PD) has led to the discovery of an increasing number of loci shown reliably to be associated with increased risk of disease. Improved understanding of the underlying genes and mechanisms at these loci will be key to understanding the pathogenesis of PD. Objective To investigate what genes and genomic processes underlie the risk of sporadic PD. Design and Setting This genetic association study used the bioinformatic tools Coloc and transcriptome-wide association study (TWAS) to integrate PD case-control GWAS data published in 2017 with expression data (from Braineac, the Genotype-Tissue Expression [GTEx], and CommonMind) and methylation data (derived from UK Parkinson brain samples) to uncover putative gene expression and splicing mechanisms associated with PD GWAS signals. Candidate genes were further characterized using cell-type specificity, weighted gene coexpression networks, and weighted protein-protein interaction networks. Main Outcomes and Measures It was hypothesized a priori that some genes underlying PD loci would alter PD risk through changes to expression, splicing, or methylation. Candidate genes are presented whose change in expression, splicing, or methylation are associated with risk of PD as well as the functional pathways and cell types in which these genes have an important role. Results Gene-level analysis of expression revealed 5 genes (WDR6 [OMIM 606031], CD38 [OMIM 107270], GPNMB [OMIM 604368], RAB29 [OMIM 603949], and TMEM163 [OMIM 618978]) that replicated using both Coloc and TWAS analyses in both the GTEx and Braineac expression data sets. A further 6 genes (ZRANB3 [OMIM 615655], PCGF3 [OMIM 617543], NEK1 [OMIM 604588], NUPL2 [NCBI 11097], GALC [OMIM 606890], and CTSB [OMIM 116810]) showed evidence of disease-associated splicing effects. Cell-type specificity analysis revealed that gene expression was overall more prevalent in glial cell types compared with neurons. The weighted gene coexpression performed on the GTEx data set showed that NUPL2 is a key gene in 3 modules implicated in catabolic processes associated with protein ubiquitination and in the ubiquitin-dependent protein catabolic process in the nucleus accumbens, caudate, and putamen. TMEM163 and ZRANB3 were both important in modules in the frontal cortex and caudate, respectively, indicating regulation of signaling and cell communication. Protein interactor analysis and simulations using random networks demonstrated that the candidate genes interact significantly more with known mendelian PD and parkinsonism proteins than would be expected by chance. Conclusions and Relevance Together, these results suggest that several candidate genes and pathways are associated with the findings observed in PD GWAS studies

Insights into the high-energy γ-ray emission of Markarian 501 from extensive multifrequency observations in the Fermi era

We report on the γ-ray activity of the blazar Mrk 501 during the first 480 days of Fermi operation. We find that the average Large Area Telescope (LAT) γ-ray spectrum of Mrk 501 can be well described by a single power-law function with a photon index of 1.78 ± 0.03. While we observe relatively mild flux variations with the Fermi-LAT (within less than a factor of two), we detect remarkable spectral variability where the hardest observed spectral index within the LAT energy range is 1.52 ± 0.14, and the softest one is 2.51 ± 0.20. These unexpected spectral changes do not correlate with the measured flux variations above 0.3 GeV. In this paper, we also present the first results from the 4.5 month long multifrequency campaign (2009 March 15-August 1) on Mrk 501, which included the Very Long Baseline Array (VLBA), Swift, RXTE, MAGIC, and VERITAS, the F-GAMMA, GASP-WEBT, and other collaborations and instruments which provided excellent temporal and energy coverage of the source throughout the entire campaign. The extensive radio to TeV data set from this campaign provides us with the most detailed spectral energy distribution yet collected for this source during its relatively low activity. The average spectral energy distribution of Mrk 501 is well described by the standard one-zone synchrotron self-Compton (SSC) model. In the framework of this model, we find that the dominant emission region is characterized by a size ≲0.1 pc (comparable within a factor of few to the size of the partially resolved VLBA core at 15-43 GHz), and that the total jet power (≃1044 erg s-1) constitutes only a small fraction (∼10-3) of the Eddington luminosity. The energy distribution of the freshly accelerated radiating electrons required to fit the time-averaged data has a broken power-law form in the energy range 0.3 GeV-10 TeV, with spectral indices 2.2 and 2.7 below and above the break energy of 20 GeV. We argue that such a form is consistent with a scenario in which the bulk of the energy dissipation within the dominant emission zone of Mrk 501 is due to relativistic, proton-mediated shocks. We find that the ultrarelativistic electrons and mildly relativistic protons within the blazar zone, if comparable in number, are in approximate energy equipartition, with their energy dominating the jet magnetic field energy by about two orders of magnitude. © 2011. The American Astronomical Society

De la teología de la liberación

La teología de la liberación nació como propósito de respuesta a los desafíos de surgen de la sociedad oprimida, y como aporte propio desde la fe al proceso mayor que va fraguando en otros campos de la vida del pueblo. Se presentan los antecedentes de esta manera de hacer teología, que se desarrolla desde la práctica eclesial, y se mencionan los principales temas teológicos y las aportaciones de la teología de la liberación. Finalmente se revisa el enfoque de la producción teológica en América Latina

Arte Sonoro y Espacio. Ampliación Atlas de conocimiento multimedia de referencias básicas del arte del siglo XX. Herramienta docente digital para primer y segundo ciclo de escultura de Bellar Artes

Memoria ID-061. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2021-2022

Very high energy gamma-ray observation of the peculiar transient event Swift J1644+57 with the MAGIC telescopes and AGILE

Context. On March 28, 2011, the BAT instrument on board the Swift satellite detected a new transient event that in the very beginning was classified as a gamma ray burst (GRB). However, the unusual X-ray flaring activity observed from a few hours up to days after the onset of the event made a different nature seem to be more likely. The long-lasting activity in the X-ray band, followed by a delayed brightening of the source in infrared and radio activity, suggested that it is better interpreted as a tidal disruption event that triggered a dormant black hole in the nucleus of the host galaxy and generated an outflowing jet of relativistic matter. Aims. Detecting a very high energy emission component from such a peculiar object would be enable us to constrain the dynamic of the emission processes and the jet model by providing information on the Doppler factor of the relativistic ejecta. Methods. The MAGIC telescopes observed the peculiar source Swift J1644+57 during the flaring phase, searching for gamma-ray emission at very-high energy (VHE, E > 100 GeV), starting observations nearly 2.5 days after the trigger time. MAGIC collected a total of 28 h of data during 12 nights. The source was observed in wobble mode during dark time at a mean zenith angle of 35 degrees. Data were reduced using a new image-cleaning algorithm, the so-called sum-cleaning, which guarantees a better noise suppression and a lower energy threshold than the standard analysis procedure. Results. No clear evidence for emission above the energy threshold of 100 GeV was found. MAGIC observations permit one to constrain the emission from the source down to 100 GeV, which favors models that explain the observed lower energy variable emission. Data analysis of simultaneous observations from AGILE, Fermi and VERITAS also provide negative detection, which additionally constrain the self-Compton emission component

Redes de colaboración para la prevención de la violencia escolar: una propuesta de mejora de la Titulación de Pedagogía en un espacio alternativo (Centro de Arte Contemporáneo DA2)

Memoria ID-0131. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2017-2018