67 research outputs found
Recommended from our members
Analysis of the Rotopod: An all revolute parallel manipulator
This paper introduces a new configuration of parallel manipulator call the Rotopod which is constructed from all revolute type joints. The Rotopod consists of two platforms connected by six legs and exhibits six Cartesian degrees of freedom. The Rotopod is initially compared with other all revolute joint parallel manipulators to show its similarities and differences. The inverse kinematics for this mechanism are developed and used to analyze the accessible workspace of the mechanism. Optimization is performed to determine the Rotopod design configurations which maximum the accessible workspace based on desirable functional constraints
The position of graptolites within Lower Palaeozoic planktic ecosystems.
An integrated approach has been used to assess the palaeoecology of graptolites both as a discrete group and also as a part of the biota present within Ordovician and Silurian planktic realms. Study of the functional morphology of graptolites and comparisons with recent ecological analogues demonstrates that graptolites most probably filled a variety of niches as primary consumers, with modes of life related to the colony morphotype. Graptolite coloniality was extremely ordered, lacking any close morphological analogues in Recent faunas. To obtain maximum functional efficiency, graptolites would have needed varying degrees of coordinated automobility. A change in lifestyle related to ontogenetic changes was prevalent within many graptolite groups. Differing lifestyle was reflected by differing reproductive strategies, with synrhabdosomes most likely being a method for rapid asexual reproduction. Direct evidence in the form of graptolithophage 'coprolitic' bodies, as well as indirect evidence in the form of probable defensive adaptations, indicate that graptolites comprised a food item for a variety of predators. Graptolites were also hosts to a variety of parasitic organisms and provided an important nutrient source for scavenging organisms
The PHENIX Experiment at RHIC
The physics emphases of the PHENIX collaboration and the design and current
status of the PHENIX detector are discussed. The plan of the collaboration for
making the most effective use of the available luminosity in the first years of
RHIC operation is also presented.Comment: 5 pages, 1 figure. Further details of the PHENIX physics program
available at http://www.rhic.bnl.gov/phenix
Adaptive preconditioning in neurological diseases - therapeutic insights from proteostatic perturbations
International audienceIn neurological disorders, both acute and chronic neural stress can disrupt cellular proteostasis, resulting in the generation of pathological protein. However in most cases, neurons adapt to these proteostatic perturbations by activating a range of cellular protective and repair responses, thus maintaining cell function. These interconnected adaptive mechanisms comprise a 'proteostasis network' and include the unfolded protein response, the ubiquitin proteasome system and autophagy. Interestingly, several recent studies have shown that these adaptive responses can be stimulated by preconditioning treatments, which confer resistance to a subsequent toxic challenge - the phenomenon known as hormesis. In this review we discuss the impact of adaptive stress responses stimulated in diverse human neuropathologies including Parkinson´s disease, Wolfram syndrome, brain ischemia, and brain cancer. Further, we examine how these responses - and the molecular pathways they recruit - might be exploited for therapeutic gai
Responses of wood anatomy and carbon isotope composition of Quercus pubescens saplings subjected to two consecutive years of summer drought
Spitzer Parallax Of Ogle-2015-blg-0966: A Cold Neptune In The Galactic Disk
We report the detection of a cold Neptune mplanet = 21 ± 2 M? orbiting a 0.38 M? M dwarf lying 2.5–3.3 kpc toward the Galactic center as part of a campaign combining ground-based and Spitzer observations to measure the Galactic distribution of planets. This is the first time that the complex real-time protocols described by Yee et al., which aim to maximize planet sensitivity while maintaining sample integrity, have been carried out in practice. Multiple survey and follow up teams successfully combined their efforts within the framework of these protocols to detect this planet. This is the second planet in the Spitzer Galactic distribution sample. Both are in the near to mid-disk and are clearly not in the Galactic bulge
Recommended from our members
Micro-telerobotic applications for microsurgery
MicroDexterity Systems Inc. and Sandia National Laboratories are collaborating on the design of a six degree-of-freedom surgeon-controlled micropositioner and a six degree-of-freedom surgeon-controlled master for use in microsurgery. A control system will provide the linkage between the force-reflecting master and micropositioner for force scaling, position scaling, and tremor filtering. The technologies developed by this project are expected to enhance the skills of surgeons, improve the success rates for existing microsurgical procedures, make new high-dexterity procedures possible, and ultimately reduce surgical costs by increasing the precision and speed of operations. This paper discusses the motivation, approach, and accomplishments to date
- …