Kinetic Study of Oxidation of Iodide Ion by N-Bromoacetamide by Stopped-flow Technique

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Study of serum leptin levels in patients with type 2 diabetes mellitus at a tertiary care centre of central India

Background: It has been reported that Insulin and leptin share a common central signaling pathway and there might be a possible role of leptin in the etiology of type 2 DM. Studies regarding role of leptin in type 2 DM in central India are lacking. Aim: This study was conducted with the aim of comparing leptin levels in patients with type 2 DM with apparently healthy controls. Subjects and Methods: A total of 80 subjects including 40 patients of type 2 DM attending outdoor clinics of MY Hospital and 40 age and sex matched healthy controls. Fasting venous blood sample was analysed for leptin, total cholesterol (TC), triglycerides (TG), HDL-C and fasting blood sugar (FBS). Statistical analysis was performed using SPSS software version 14. Results: Mean BMI of diabetic group was 32 ± 3.48kg/m2 and that of control group was 28 ± 2.56kg/m2. Leptin levels among diabetic cases were 29.3± 19.3 ng/ml and in non diabetic subjects it was 34.8 ±21.4 ng/ml. The difference in leptin levels between cases and control were statistically significant. Conclusion: Low leptin levels are associated with type 2 diabetes mellitus independent of changes in BMI

Genetic Variation for Traits Related to Phosphorus Use Efficiency in Lens Species at the Seedling Stage

Phosphorus (P) is an essential, non-renewable resource critical for crop productivity across the world. P is immobile in nature and, therefore, the identification of novel genotypes with efficient P uptake and utilization under a low P environment is extremely important. This study was designed to characterize eighty genotypes of different Lens species for shoot and root traits at two contrasting levels of P. A significant reduction in primary root length (PRL), total surface area (TSA), total root tips (TRT), root forks (RF), total dry weight (TDW), root dry weight (RDW) and shoot dry weight (SDW) in response to P deficiency was recorded. A principal component analysis revealed that the TDW, SDW and RDW were significantly correlated to P uptake and utilization efficiency in lentils. Based on total dry weight (TDW) under low P, L4727, EC718309, EC714238, PL-97, EC718348, DPL15, PL06 and EC718332 were found promising. The characterization of different Lens species revealed species-specific variations for the studied traits. Cultivated lentils exhibited higher P uptake and utilization efficiency as compared to the wild forms. The study, based on four different techniques, identified EC714238 as the most P use-efficient genotype. The genotypes identified in this study can be utilized for developing mapping populations and deciphering the genetics for breeding lentil varieties suited for low P environments