Spatial Distribution of Runoff Discharges Considering Wadi Channel Flow with Upscaling Technique Based on Homogenization

Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv

An Approach to the Adaptive Flood Control by Multi-Reservoir Systems

The aim of this study is to establish a procedure for the adaptive flood control by multi-reservoir systems. The multi-reservoir systems have several reservoirs located in series, parallel, or mixed type and several flood defence points. The foundamental idea is to combine the typhoon simulation techniques with the optimal operation techniques based on Dynamic Programming. That is to say, at every control time, many typhoons are simulated according to the stochastic structures of a typhoon. And for each simulated typhoon, an optimal release flow at the control time will be decided in a sense of a probability of exceedance, or a safety rate based on the frequency distribution estimated from the set of the above optimal release flow. Of course, the simulated results antecedent to the control time will be compared with the observed ; and through the feedback loop, the characteristic parameters will be corrected. From this point of view, we may consider this procedure as an approach to “the adaptive flood control”

Tide Prediction for the Downstream Boundary Condition of the Chao-Phraya River Integrated River Model Using Harmonic Analysis

Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv

Collaborative Engineering and Hydroinformatics: The Hydroasia Experience

Source: ICHE Conference Archive - https://mdi-de.baw.de/icheArchiv

Heterocyclic scaffolds as promising anticancer agents against tumours of the central nervous system: Exploring the scope of indole and carbazole derivatives

Tumours of the central nervous system are intrinsically more dangerous than tumours at other sites, and in particular, brain tumours are responsible for 3% of cancer deaths in the UK. Despite this, research into new therapies only receives 1% of national cancer research spend. The most common chemotherapies are temozolomide, procarbazine, carmustine, lomustine and vincristine, but because of the rapid development of chemoresistance, these drugs alone simply aren’t sufficient for long-term treatment. Such poor prognosis of brain tumour patients prompted us to research new treatments for malignant glioma, and in doing so, it became apparent that aromatic heterocycles play an important part, especially the indole, carbazole and indolocarbazole scaffolds. This review highlights compounds in development for the treatment of tumours of the central nervous system which are structurally based on the indole, carbazole and indolocarbazole scaffolds, under the expectation that it will highlight new avenues for research for the development of new compounds to treat these devastating neoplasms

Salinity intrusion: its characteristics and impact - cases in the Asia Pacific region

[Abstract]: Anthropogenic impacts on hydro-geological systems can result in long term harm and the degradation of the resource if they are not adequately managed. While this is well known, and witnessed around the world, management options to prevent increasing damage to the surrounding environment are being developed on an individual site basis. Salinity intrusion with the eventual degradation of both land and water quality is one of the most common examples of this type of problem. This paper presents our observations and analyses of salinity intrusion at selected areas in the Asia Pacific region, namely in New Zealand, Australia, Japan and Sri Lanka. It discusses the characteristics of each site and analyzes the impacts on the environment. It also presents the management practices used to mitigate the resulting damage on the environment at each site

Optimal Planning of Flood Control Systems Based on Screening, Simulation and Sequential Models

The aim of this study is to establish the optimal flood control system accounted for by the comprehensive criteria on the whole river basin. Especially, we will examine the effects of flood control projects in the system consisting of multi-sub-basin and multi-defense points against flood inundation probability in time and space. We define the planning problem of flood control projects as the minimization problem of the construction cost among all alternatives while satisfying the required safety rate for the prevention of flood inundation. First, the better alternatives are extracted by using the random search method. Second, the optimal system on the exact basin model is determined by appliaction of the simulation method for them. Lastly, the optimal construction order of the final system is gained by Dynamic Programming with the criteria that the expectation of the inundation damage under construction is minimized. So, we call the above three steps i) Screening model, ii) Simulation model and iii) Sequential model in flood control planning, respectively