78 research outputs found

    Using WinBUGS to Study Family Frailty in Child Mortality, with an Application to Child Survival in Ivory Coast

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    This article analyzes the effects of unobserved family heterogeneity in children survival times through a Bayesian approach. We rely on survey data from Ivory Coast and use a proportional hazard model with multiplicative random effect. With such a model, the usual assumption of independence of observations is avoided. The posterior distributions of the parameters are estimated through a Gibbs sampler algorithm using the WinBUGS software. This technique overcomes the possible local convergence problem observed with the commonly used Expectation-Maximization method

    Modelling and forecasting mortality in Spain

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    [EN] Experience shows that static life tables overestimate death probabilities. As a consequence of this overestimation the premiums for annuities, pensions and life insurance are not what they actually should be, with negative effects for insurance companies or policy-holders. The reason for this overestimation is that static life tables, through being computed for a specific period of time, cannot take into account the decreasing mortality trend over time. Dynamic life tables overcome this problem by incorporating the influence of the calendar when graduating mortality. Recent papers on the topic look for the development of new methods to deal with this dynamism. Most methods used in dynamic tables are parametric, apply traditional mortality laws and then analyse the evolution of estimated parameters with time series techniques. Our contribution consists in extending and applying Lee–Carter methods to Spanish mortality data, exploring residuals and future trends.This work was partially supported by a grant from MEyC (Ministerio de Educacio´n y Ciencia, Spain, project MTM-2004-06231). The research of Francisco Montes has also been partially supported by a grant from DGITT (Direccio´ General d’Investigacio´ i Transfere`ncia Tecnolo`gica de la Generalitat Valenciana, project GRUPOS03/189).Debón Aucejo, AM.; Montes, F.; Puig, F. (2008). Modelling and forecasting mortality in Spain. European Journal of Operational Research. 189(3):624-637. https://doi.org/10.1016/j.ejor.2006.07.050S624637189

    Bridging the age gap: a prognostic model that predicts survival and aids in primary treatment decisions for older women with oestrogen receptor‐positive early breast cancer

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    Background A prognostic model was developed and validated using cancer registry data. This underpins an online decision support tool, informing primary treatment choice for women aged 70 years or older with hormone receptor‐positive early breast cancer. Methods Data from women diagnosed between 2002 and 2010 in the English Northern and Yorkshire and West Midlands regions were used to develop the model. Primary treatment options of surgery with adjuvant endocrine therapy or primary endocrine therapy were compared. Models predicting the hazard of breast cancer‐specific mortality and hazard of other‐cause mortality were combined to derive survival probabilities. The model was validated externally using data from the Eastern Cancer Registration and Information Centre. Results The model was developed using data from 23 842 women, and validated externally on a data set from 14 526 patients. The overall model calibration was good. At 2 and 5 years, predicted mortality from breast cancer and other causes differed from the observed rate by less than 1 per cent. At 5 years, there were slight overpredictions in breast cancer mortality (2629 predicted versus 2556 observed deaths; P  = 0·142) and mortality from all causes (6399 versus 6320 respectively; P  = 0·583). The discrepancy varied between subgroups. Model discrimination was 0·75 or above for all mortality measures. Conclusion A prognostic model for older women with oestrogen receptor‐positive early breast cancer was developed and validated in the present study. This forms a basis for an online decision support tool (https://agegap.shef.ac.uk/)

    A comparative study of two population models for the assessment of basis risk in longevity hedges

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    Longevity swaps have been one of the major success stories of pension scheme derisking in recent years. However, with some few exceptions, all of the transactions to date have been bespoke longevity swaps based upon the mortality experience of a portfolio of named lives. In order for this market to start to meet its true potential, solutions will ultimately be needed that provide protection for all types of members, are cost effective for large and smaller schemes, are tradable, and enable access to the wider capital markets. Index-based solutions have the potential to meet this need; however concerns remain with these solutions. In particular, the basis risk emerging from the potential mismatch between the underlying forces of mortality for the index reference portfolio and the pension fund/annuity book being hedged is the principal issue that has, to date, prevented many schemes progressing their consideration of index-based solutions. Two-population stochastic mortality models offer an alternative to overcome this obstacle as they allow market participants to compare and project the mortality experience for the reference and target populations and thus assess the amount of demographic basis risk involved in an index-based longevity hedge. In this paper, we systematically assess the suitability of several multi-population stochastic mortality models for assessing basis risks and provide guidelines on how to use these models in practical situations paying particular attention to the data requirements for the appropriate calibration and forecasting of such models
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