134 research outputs found

    Systemic hypertension in cats with acute kidney injury

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    Retrospective study of cats presenting to the Queen Mother Hospital for Animals, Royal Veterinary College with acute kidney injury between 2007 and 2015. Systolic blood pressure was measured using Doppler sphygmomanometry and systemic hypertension was defined pressures ĂȘ150 mmHg. Median systolic blood pressure measurement, grade of acute kidney injury (as defined by the International Renal Interest Society), serum creatinine on admission, anuria or oliguria, length of hospitalisation, survival to discharge and six‐month survival were all recorded

    Dose-dependent effect of parenteral iron therapy on bleomycin-detectable iron in immune apheresis patients

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    Dose-dependent effect of parenteral iron therapy on bleomycin-detectable iron in immune apheresis patients.BackgroundIron deficiency and anemia are commonly encountered in patients with autoimmune diseases undergoing immune apheresis. This makes erythropoietin and iron substitution necessary in most patients. However, intravenous iron therapy may result in an increase of potentially toxic nontransferrin-bound iron.MethodsWe examined the effect of 50 mg or 100 mg of iron (III) sucrose on bleomycin-detectable iron (BDI) in immune apheresis patients. Six patients with autoimmune disorders and normal kidney function were enrolled. Before and after the injection of 50 mg or 100 mg of iron (III) sucrose, BDI was measured in serum samples at five different time points.ResultsThere was no BDI traceable before injection of iron (III) sucrose. BDI was present in serum of all patients after the administration of 100 mg of iron (III) sucrose in concentrations up to 0.49 ÎŒmol/L. In contrast, only one patient showed BDI at a concentration of 0.16 ÎŒmol/L after the administration of 50 mg of iron (III) sucrose.ConclusionWe conclude that if parenteral iron is administered after apheresis treatment, despite the equal tolerability, use of 50 mg of iron (III) sucrose is superior to 100 mg of iron (III) sucrose in avoiding the formation of potentially toxic nontransferrin-bound iron

    ACVIM consensus statement: Guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats

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    An update to the 2007 American College of Veterinary Internal Medicine (ACVIM) consensus statement on the identification, evaluation, and management of systemic hypertension in dogs and cats was presented at the 2017 ACVIM Forum in National Harbor, MD. The updated consensus statement is presented here. The consensus statement aims to provide guidance on appropriate diagnosis and treatment of hypertension in dogs and cats

    LUBRA - a code to calculate point and group cross sections, effective resonance integrals and doppler coefficients for reasonable absorbers in homogeneous reactors, using Breit-Wigner single-level resonance parameters.

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    The LUBRA complex of codes is designed to produce (i) point cross sections, (ii) infinitely dilute resonance integrals, (iii) effective resonance integrals based on the different approximations presently available and optionally modified to include particle size effects, (iv) Doppler coefficients, also based on the various models, and (v) group averaged cross sections, using Breit-Wigner single—level resonance parameters and other basic data only. The complex currently comprises five individual programmes coded in FORTRAN IV for an IBM 7040 computer and linked together by a specialised monitor system to permit the use of LUBRA as a single entity

    MULGA - a complex of codes for the determination of multigroup averaged neutron cross section data.

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    A complex of computer programmes called MULGA is described which will produce multigroup cross sections in a format suitable for input into a selection of reactor codes. Always bearing in mind that the spatial variation of flux will frustrate any determination of "exact" cross sections the maximum accuracy has been striven for within the limitations of urgency and feasibility. The programmes; together with an associated microscopic data library tape, and a specialised monitor system, have been coded for an IBM 1620 computer with 4 magnetic tapes. The basic programmes MULGA 1 and MULGA 2 have already been adapted for an ISM 7090 and the whole series will be modified for the new site computer in 1964
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