320 research outputs found
A Qualitative Comparison of ANSYS and OpenFOAM results for Carbon dioxide Plume Transport
This research presents Computational Fluid Dynamics (CFD) simulations in ANSYSÂź illustrating emissions of to the air. The CFD simulations is employed to study plume transport in urban environment, i.e., Breivika port in the city of TromsĂž. The case study presents a two-phase model considering specific wind strength and direction in the city of TromsĂž. Geographical coordinates, temperature, and wind data were obtained from the open sources, such as Google Maps, and Norwegian Meteorological Institute. The results from the simulations indicates a potential outcome with respect to various weather conditions. It was revealed for vessels less than 30 meter chimney height, the higher the wind strength, the lower the plume dispersion, causing the plume to stay closer to the terrain. This brings in a concentrated amount of pollutants closer to the public areas. The terrain in the model is recognizable for the TromsĂž portâs location. From the CFD results, it is illustrated that onshore wind with high wind strength could affect the environment. The results simulated in OpenFOAM are qualitatively showing the same as visible in ANSYSÂź
Population structure and connectivity of the mountainous star coral, Orbicella faveolata , throughout the wider Caribbean region
As coral reefs continue to decline worldwide, it becomes ever more necessary to understand the connectivity between coral populations to develop efficient management strategies facilitating survival and adaptation of coral reefs in the future. Orbicella faveolata is one of the most important reef-building corals in the Caribbean and has recently experienced severe population reductions. Here, we utilize a panel of nine microsatellite loci to evaluate the genetic structure of O. faveolata and to infer connectivity across ten sites spanning the wider Caribbean region. Populations are generally well-mixed throughout the basin (FST = 0.038), although notable patterns of substructure arise at local and regional scales. Eastern and western populations appear segregated with a genetic break around the Mona Passage in the north, as has been shown previously in other species; however, we find evidence for significant connectivity between Curaçao and Mexico, suggesting that the southern margin of this barrier is permeable to dispersal. Our results also identify a strong genetic break within the Mesoamerican Barrier Reef System associated with complex oceanographic patterns that promote larval retention in southern Belize. Additionally, the diverse genetic signature at Flower Garden Banks suggests its possible function as a downstream genetic sink. The findings reported here are relevant to the ongoing conservation efforts for this important and threatened species, and contribute to the growing understanding of large-scale coral reef connectivity throughout the wider Caribbean
Population structure and connectivity of the mountainous star coral, Orbicella faveolata , throughout the wider Caribbean region
As coral reefs continue to decline worldwide, it becomes ever more necessary to understand the connectivity between coral populations to develop efficient management strategies facilitating survival and adaptation of coral reefs in the future. Orbicella faveolata is one of the most important reef-building corals in the Caribbean and has recently experienced severe population reductions. Here, we utilize a panel of nine microsatellite loci to evaluate the genetic structure of O. faveolata and to infer connectivity across ten sites spanning the wider Caribbean region. Populations are generally well-mixed throughout the basin (FST = 0.038), although notable patterns of substructure arise at local and regional scales. Eastern and western populations appear segregated with a genetic break around the Mona Passage in the north, as has been shown previously in other species; however, we find evidence for significant connectivity between Curaçao and Mexico, suggesting that the southern margin of this barrier is permeable to dispersal. Our results also identify a strong genetic break within the Mesoamerican Barrier Reef System associated with complex oceanographic patterns that promote larval retention in southern Belize. Additionally, the diverse genetic signature at Flower Garden Banks suggests its possible function as a downstream genetic sink. The findings reported here are relevant to the ongoing conservation efforts for this important and threatened species, and contribute to the growing understanding of large-scale coral reef connectivity throughout the wider Caribbean
Thermal compression of atomic hydrogen on helium surface
We describe experiments with spin-polarized atomic hydrogen gas adsorbed on
liquid He surface. The surface gas density is increased locally by
thermal compression up to cm at 110 mK. This
corresponds to the onset of quantum degeneracy with the thermal de-Broglie
wavelength being 1.5 times larger than the mean interatomic spacing. The atoms
were detected directly with a 129 GHz electron-spin resonance spectrometer
probing both the surface and the bulk gas. This, and the simultaneous
measurement of the recombination power, allowed us to make accurate studies of
the adsorption isotherm and the heat removal from the adsorbed hydrogen gas.
From the data, we estimate the thermal contact between 2D hydrogen gas and
phonons of the helium film. We analyze the limitations of the thermal
compression method and the possibility to reach the superfluid transition in 2D
hydrogen gas.Comment: 20 pages, 11 figure
The occurrence and receptor specificity of endogenous opioid peptides within the pancreas and liver of the rat. Comparison with brain
Nonlinear coherent states and Ehrenfest time for Schrodinger equation
We consider the propagation of wave packets for the nonlinear Schrodinger
equation, in the semi-classical limit. We establish the existence of a critical
size for the initial data, in terms of the Planck constant: if the initial data
are too small, the nonlinearity is negligible up to the Ehrenfest time. If the
initial data have the critical size, then at leading order the wave function
propagates like a coherent state whose envelope is given by a nonlinear
equation, up to a time of the same order as the Ehrenfest time. We also prove a
nonlinear superposition principle for these nonlinear wave packets.Comment: 27 page
A systematic review and meta-analysis of the use of renin-angiotensin system drugs and COVID-19 clinical outcomes : What is the evidence so far?
Peer reviewedPublisher PD
Finite temperature excitations of a trapped Bose-Fermi mixture
We present a detailed study of the low-lying collective excitations of a
spherically trapped Bose-Fermi mixture at finite temperature in the
collisionless regime. The excitation frequencies of the condensate are
calculated self-consistently using the static Hartree-Fock-Bogoliubov theory
within the Popov approximation. The frequency shifts and damping rates due to
the coupled dynamics of the condensate, noncondensate, and degenerate Fermi gas
are also taken into account by means of the random phase approximation and
linear response theory. In our treatment, the dipole excitation remains close
to the bare trapping frequency for all temperatures considered, and thus is
consistent with the generalized Kohn theorem. We discuss in some detail the
behavior of monopole and quadrupole excitations as a function of the Bose-Fermi
coupling. At nonzero temperatures we find that, as the mixture moves towards
spatial separation with increasing Bose-Fermi coupling, the damping rate of the
monopole (quadrupole) excitation increases (decreases). This provides us a
useful signature to identify the phase transition of spatial separation.Comment: 10 pages, 8 figures embedded; to be published in Phys. Rev.
Use of smokeless tobacco among groups of Pakistani medical students â a cross sectional study
<p>Abstract</p> <p>Background</p> <p>Use of smokeless tobacco is common in South Asia. Tobacco is a major preventable cause of morbidity and mortality. Doctors make one of the best avenues to influence patients' tobacco use. However, medical students addicted to tobacco are likely to retain this habit as physicians and are unlikely to counsel patients against using tobacco. With this background, this study was conducted with the objective of determining the prevalence of smokeless tobacco among Pakistani medical students.</p> <p>Methods</p> <p>A cross sectional study was carried out in three medical colleges of Pakistan â one from the north and two from the southern region. 1025 students selected by convenient sampling completed a peer reviewed, pre-tested, self-administered questionnaire. Questions were asked regarding lifetime use (at least once or twice in their life), current use (at least once is the last 30 days), and established use (more than 100 times in their life) of smokeless tobacco. Chi square and logistic regression analyses were used.</p> <p>Results</p> <p>Two hundred and twenty (21.5%) students had used tobacco in some form (smoked or smokeless) in their lifetime. Sixty six (6.4%) students were lifetime users of smokeless tobacco. Thirteen (1.3%) were daily users while 18 (1.8%) fulfilled the criterion for established users. Niswar was the most commonly used form of smokeless tobacco followed by paan and nass. Most naswar users belonged to NWFP while most paan users studied in Karachi. On univariate analysis, lifetime use of smokeless tobacco showed significant associations with the use of cigarettes, student gender (M > F), student residence (boarders > day scholars) and location of the College (NWFP > Karachi). Multivariate analysis showed independent association of lifetime use of smokeless tobacco with concomitant cigarette smoking, student gender and location of the medical college.</p> <p>Conclusion</p> <p>The use of smokeless tobacco among medical students cannot be ignored. The governments should add the goal of eliminating smokeless tobacco to existing drives against cigarette smoking. Drives in Karachi should focus more on eliminating paan usage while those in NWFP should focus more on the use of naswar. Medical colleges should provide greater education about the myths and hazards of smokeless tobacco.</p
Bi-allelic JAM2 Variants Lead to Early-Onset Recessive Primary Familial Brain Calcification.
Primary familial brain calcification (PFBC) is a rare neurodegenerative disorder characterized by a combination of neurological, psychiatric, and cognitive decline associated with calcium deposition on brain imaging. To date, mutations in five genes have been linked to PFBC. However, more than 50% of individuals affected by PFBC have no molecular diagnosis. We report four unrelated families presenting with initial learning difficulties and seizures and later psychiatric symptoms, cerebellar ataxia, extrapyramidal signs, and extensive calcifications on brain imaging. Through a combination of homozygosity mapping and exome sequencing, we mapped this phenotype to chromosome 21q21.3 and identified bi-allelic variants in JAM2. JAM2 encodes for the junctional-adhesion-molecule-2, a key tight-junction protein in blood-brain-barrier permeability. We show that JAM2 variants lead to reduction of JAM2 mRNA expression and absence of JAM2 protein in patient's fibroblasts, consistent with a loss-of-function mechanism. We show that the human phenotype is replicated in the jam2 complete knockout mouse (jam2 KO). Furthermore, neuropathology of jam2 KO mouse showed prominent vacuolation in the cerebral cortex, thalamus, and cerebellum and particularly widespread vacuolation in the midbrain with reactive astrogliosis and neuronal density reduction. The regions of the human brain affected on neuroimaging are similar to the affected brain areas in the myorg PFBC null mouse. Along with JAM3 and OCLN, JAM2 is the third tight-junction gene in which bi-allelic variants are associated with brain calcification, suggesting that defective cell-to-cell adhesion and dysfunction of the movement of solutes through the paracellular spaces in the neurovascular unit is a key mechanism in CNS calcification
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