Male and female physical intimate partner violence and socioeconomic position: a cross-sectional international multicentre study in Europe

Objectives: This work explores the association between socioeconomic position (SEP) and intimate partner violence (IPV) considering the perspectives of men and women as victims, perpetrators and as both (bidirectional). Study Design: Cross-sectional international multicentre study. Methods: A sample of 3496 men and women, (aged 18-64 years), randomly selected from the general population of residents from six European cities was assessed: Athens, Budapest, London, Östersund, Porto and Stuttgart. Their education (primary, secondary and university), occupation (upper white-collar, lower white-collar and blue collar) and unemployment duration (never, ≤12 months and >12 months) were considered as SEP indicators and physical IPV was measured with the Revised Conflict Tactics Scales. Results: Past year physical IPV was declared by 17.7% of women (3.5% victims, 4.2% perpetrators and 10.0% bidirectional) and 19.8% of men (4.1% victims, 3.8% perpetrators and 11.9% bidirectional). Low educational level (primary vs. university) was associated with female victimization (adjusted Odds Ratio, 95% confidence interval: 3.2, 1.3-8.0) and with female bidirectional IPV (4.1, 2.4-7.1). Blue collar occupation (vs. upper white) was associated with female victimization (2.1, 1.1-4.0), female perpetration (3.0, 1.3-6.8) and female bidirectional IPV (4.0, 2.3-7.0). Unemployment duration was associated with male perpetration (> 12 months of unemployment vs. never unemployed: 3.8, 1.7-8.7) and with bidirectional IPV in both sex (women: 1.8, 1.2-2.7; men: 1.7, 1.0-2.8). Conclusions: In these European centers, physical IPV was associated with a disadvantaged socioeconomic position. A consistent socioeconomic gradient was observed in female bidirectional involvement, but victims or perpetrators-only presented gender specificities according to levels of education, occupation differentiation and unemployment duration potentially useful for designing interventions

Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer

Tumor-associated dendritic cells are defective in their ability to cross-present antigens, and they accumulate lipid bodies. Here the authors show that this defect is due to an impaired trafficking of peptide-MHC class I caused by the interaction of electrophilic lipids with chaperone heat shock protein 70

EuCAPT White Paper: Opportunities and Challenges for Theoretical Astroparticle Physics in the Next Decade

Astroparticle physics is undergoing a profound transformation, due to a series of extraordinary new results, such as the discovery of high-energy cosmic neutrinos with IceCube, the direct detection of gravitational waves with LIGO and Virgo, and many others. This white paper is the result of a collaborative effort that involved hundreds of theoretical astroparticle physicists and cosmologists, under the coordination of the European Consortium for Astroparticle Theory (EuCAPT). Addressed to the whole astroparticle physics community, it explores upcoming theoretical opportunities and challenges for our field of research, with particular emphasis on the possible synergies among different subfields, and the prospects for solving the most fundamental open questions with multi-messenger observations.Comment: White paper of the European Consortium for Astroparticle Theory (EuCAPT). 135 authors, 400 endorsers, 133 pages, 1382 reference

Green computing in underwater wireless sensor networks pressure centric energy modeling

[EN] Underwater wireless sensor networks (UWSNs) have witnessed significant attention from both industries and academia in research and development. This is due to the wide range of applications including scientific, commercial, military, and environmental. Considering the peculiar characteristics and harsh environments of UWSNs, reliable green communication among sensor nodes in the network is one of the major challenging tasks. In this context, this article proposes a localization-free shortest path reliable and energy-efficient pressure-based routing (SPRE-PBR) protocol for UWSNs. SPRE-PBR considers three parameters including residual energy, pressure, and link quality for selecting the next forwarding nodes. Moreover, SPRE-PBR is designed and developed to control path selection and reduce the unnecessary forwarding based on route cost calculation and optimal shortest path algorithm. The comprehensive performance evaluation attests the benefit of SPRE-PBR as compared with the state-of-the-art techniques considering underwater networking centric metrics.This work was supported by the the Amman Arab University, Jordan, and Nottingham Trent University, UK.Khasawneh, AM.; Kaiwartya, O.; Khalifeh, A.; Abualigah, LM.; Lloret, J. (2020). Green Computing in Underwater Wireless Sensor Networks Pressure Centric Energy Modeling. IEEE Systems Journal. 14(4):4735-4745. https://doi.org/10.1109/JSYST.2020.29964214735474514

An efficient void aware framework for enabling Internet of Underwater Things

The Internet of Underwater Things (IoUT) is an emerging area in marine science and engineering. It has witnessed significant research and development attention from both academia and industries due to its growing underwater use cases in oceanographic data collection, pollution monitoring, seismic monitoring, tactical surveillance, and assisted navigation for waterway transport. Information dissemination in the underwater network environment is very critical considering network dynamism, unattainable nodes, and limited resources of the tiny IoUT devices. Existing techniques are majorly based on location-centric beacon messages, which results in higher energy consumption, and wastage of computing resources in tiny IoUT devices. Towards this end, this paper presents an efficient void aware (EVA) framework for information dissemination in IoUT environment. Network architecture is modeled considering potential void region identification in the underwater network environment. An efficient void aware (EVA) information dissemination framework is proposed focusing on detecting void network region, and intelligent void aware data forwarding. The comparative performance evaluation attests to the benefits of the proposed framework in terms of energy consumption, network lifetime, packet delivery ratio, and end-to-end delay for information dissemination in IoUT

Hematuria Cancer Risk Score with Ultrasound Informs Cystoscopy Use in Patients with Hematuria.

BACKGROUND: Hematuria is a cardinal symptom of urinary tract cancer and would require further investigations. OBJECTIVE: To determine the ability of renal bladder ultrasound (RBUS) with the Hematuria Cancer Risk Score (HCRS) to inform cystoscopy use in patients with hematuria. DESIGN, SETTING, AND PARTICIPANTS: The development cohort comprised 1984 patients with hematuria from 40 UK hospitals (DETECT 1; ClinicalTrials.gov: NCT02676180) who received RBUS. An independent validation cohort comprised 500 consecutive patients referred to secondary care for a suspicion of bladder cancer. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Sensitivity and true negative of the HCRS and RBUS were assessed. RESULTS AND LIMITATIONS: A total of 134 (7%) and 36 (8%) patients in the development and validation cohorts, respectively, had a diagnosis of urinary tract cancer. Validation of the HCRS achieves good discrimination with an area under the receiver operating characteristic curve of 0.727 (95% confidence interval 0.648-0.800) in the validation cohort with sensitivity of 95% for the identification of cancer. Utilizing the cutoff of 4.500 derived from the HCRS in combination with RBUS in the development cohort, 680 (34%) patients would have been spared cystoscopy at the cost of missing a G1 Ta bladder cancer and a urinary tract cancer patient, while 117 (25%) patients would have avoided cystoscopy at the cost of missing a single patient of G1 Ta bladder cancer with sensitivity for the identification of cancer of 97% in the validation cohort. CONCLUSIONS: The HCRS with RBUS offers good discriminatory ability in identifying patients who would benefit from cystoscopy, sparing selected patient cohorts from an invasive procedure. PATIENT SUMMARY: The hematuria cancer risk score with renal bladder ultrasound allows for the triage of patients with hematuria who would benefit from visual examination of the bladder (cystoscopy). This resulted in 25% of patients safely omitting cystoscopy, which is an invasive procedure, and would lead to health care cost savings