Building a CCD Spectrograph for Educational or Amateur Astronomy

We discuss the design of an inexpensive, high-throughput CCD spectrograph for a small telescope. By using optical fibers to carry the light from the telescope focus to a table-top spectrograph, one can minimize the weight carried by the telescope and simplify the spectrograph design. We recently employed this approach in the construction of IntroSpec, an instrument built for the 16-inch Knowles Telescope on the Harvard College campus.Comment: 17 pages including 7 figures, PASP, accepted (higher resolution figures at http://cfa-www.harvard.edu/~sheila/introspec.ps.gz

Targeting Inflammatory Pathways by Triterpenoids for Prevention and Treatment of Cancer

Traditional medicine and diet has served mankind through the ages for prevention and treatment of most chronic diseases. Mounting evidence suggests that chronic inflammation mediates most chronic diseases, including cancer. More than other transcription factors, nuclear factor-kappaB (NF-κB) and STAT3 have emerged as major regulators of inflammation, cellular transformation, and tumor cell survival, proliferation, invasion, angiogenesis, and metastasis. Thus, agents that can inhibit NF-κB and STAT3 activation pathways have the potential to both prevent and treat cancer. In this review, we examine the potential of one group of compounds called triterpenes, derived from traditional medicine and diet for their ability to suppress inflammatory pathways linked to tumorigenesis. These triterpenes include avicins, betulinic acid, boswellic acid, celastrol, diosgenin, madecassic acid, maslinic acid, momordin, saikosaponins, platycodon, pristimerin, ursolic acid, and withanolide. This review thus supports the famous adage of Hippocrates, “Let food be thy medicine and medicine be thy food”

Physical Sources of Scatter in the Tully-Fisher Relation

We analyze residuals from the Tully-Fisher relation for the emission-line galaxies in the Nearby Field Galaxy Survey, a broadly representative survey designed to fairly sample the variety of galaxy morphologies and environments in the local universe. For spirals brighter than M_R^i=-18, we find strong correlations between Tully-Fisher residuals and both B-R color and EW(Halpha). The extremes of the correlations are populated by Sa galaxies, which show consistently red colors, and spirals with morphological peculiarities, which are often blue. If we apply an EW(Halpha)-dependent or B-R color-dependent correction term to the Tully-Fisher relation, the scatter in the relation no longer increases from R to B to U but instead drops to a nearly constant level close to the scatter we expect from measurement errors. We argue that these results probably reflect correlated offsets in luminosity and color as a function of star formation history. Broadening the sample in morphology and luminosity, we find that most non-spirals brighter than M_R^i=-18 follow the same correlations as do spirals, albeit with greater scatter. However, the color and EW(Halpha) correlations do not apply to galaxies fainter than M_R^i=-18 or to emission-line S0 galaxies with anomalous gas kinematics. For the dwarf galaxy population, the parameters controlling Tully-Fisher residuals are instead related to the degree of recent disturbance: overluminous dwarfs have higher rotation curve asymmetries, brighter U-band effective surface brightnesses, and shorter gas consumption timescales than their underluminous counterparts. As a result, sample selection strongly affects the measured faint-end slope of the Tully-Fisher relation. Passively evolving, rotationally supported galaxies display a break toward steeper slope at low luminosities.Comment: 58 pages including 21 figures, AJ, accepte

Forming Young Bulges within Existing Disks: Statistical Evidence for External Drivers

Contrary to traditional models of galaxy formation, recent observations suggest that some bulges form within preexisting disk galaxies. Such late-epoch bulge formation within disks seems to be linked to disk gas inflow and central star formation, caused by either internal secular processes or galaxy mergers and interactions. We identify a population of galaxies likely to be experiencing active bulge growth within disks, using the criterion that the color within the half-light radius is bluer than the outer disk color. Such blue-centered galaxies make up >10% of star-forming disk galaxies within the Nearby Field Galaxy Survey, a broad survey designed to represent the natural diversity of the low-z galaxy population over a wide range of luminosities and environments. Blue-centered galaxies correlate at 99% confidence with morphological peculiarities suggestive of minor mergers and interactions. From this and other evidence, we argue that external drivers rather than internal secular processes probably account for the majority of blue-centered galaxies. We go on to discuss quantitative plausibility arguments indicating that blue-centered evolutionary phases may represent an important mode of bulge growth for most disk galaxies, leading to significant changes in bulge-to-disk ratio without destroying disks. If this view is correct, bulge growth within disks may be a natural consequence of the repeated galaxy mergers and interactions inherent in hierarchical galaxy formation.Comment: 18 pages including 12 figures, AJ, accepte

Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake (vol 80, vol 1021, 2010)

Retraction notice to “Cyclodextrin-complexed curcumin exhibits anti-inflammatory and antiproliferative activities superior to those of curcumin through higher cellular uptake” [Biochem. Pharmacol. 80 (2010) 1021–1032].Non peer reviewe

Microstructure and wear behaviour of high alloyed hot-work tool steels 1.2343 and 1.2367 under thermo-mechanical loading

Tools and their maintenance costs in hot forging processes account for a considerable proportion of the total components' costs. Forging tools undergo extreme heating and subsequent cooling during the forging process and between the forging cycles, respectively. This cyclic heating and cooling of the tool surfaces leads to local changes in the tool microstructure which result in hardening or softening of the material in different regions of the tool and consequently influence the tool strength. Temperature in the tool areas experiencing high thermo-mechanical loadings can exceed the austenitic temperature. Hence, a strong cooling, for example by spraying or lubrication, can lead to formation of a martensitic layer in the boundary zone of the tool. Due to its higher hardness, martensitic layer has greater resistance to wear as compared to the basic or tempered materials. In the scope of this paper, the austenitisation behaviours of two high alloyed hot-work tool steels, 1.2343 and 1.2367, have been characterized by means of dilatometer tests to obtain time-temperature-austenitisation (TTA) diagrams for specimen under thermo-mechanical loads. Moreover, continuous-cooling-transformation (CCT) diagrams were recorded. Metallographic investigations were carried out to gather a detailed understanding of the microstructure behaviour and its resulting hardness. With the results of this works, it is aimed to gather a detailed and accurate insight into the arising hardening and softening effects. This would eventually lead to an optimisation of the numerical modelling for tool wear prediction

A forming disk at z~0.6: Collapse of a gaseous disk or major merger remnant?

[Abridged] We present and analyze observations of J033241.88-274853.9 at z=0.6679, using multi-wavelength photometry and imaging with FLAMES/GIRAFFE 3D spectroscopy. J033241.88-274853.9 is found to be a blue, young (~320Myr) stellar disk embedded in a very gas-rich (fgas=73-82% with log(Mstellar/Mo)=9.45) and turbulent phase that is found to be rotating on large spatial scales. We identified two unusual properties of J033241.88-274853.9. (1) The spatial distributions of the ionized gaseous and young stars show a strong decoupling; while almost no stars can be detected in the southern part down to the very deep detection limit of ACS/UDF images, significant emission from the [OII] ionized gas is detected. (2) We detect an excess of velocity dispersion in the southern part of J033241.88-274853.9 in comparison to expectations from a rotating disk model. We considered two disk formation scenarios, depending on the gaseous phase geometry. In the first one, we examined whether J033241.88-274853.9 could be a young rotating disk that has been recently collapsed from a pre-existing, very gas-rich rotating disk. This scenario requires two (unknown) additional assumptions to explain the decoupling between the distribution of stars and gas and the excess of velocity dispersion in the same region. In a second scenario, we examine whether J033241.88-274853.9 could be a merger remnant of two gas-rich disks. In this case, the asymmetry observed between the gas and star distributions, as well as the excess of velocity dispersion, find a common explanation. Shocks produced during the merger in this region can be ionized easily and heat the gas while preventing star formation. This makes this scenario more satisfactory than the collapse of a pre-existing, gas-rich rotating disk.Comment: Accepted for publication in A&A. 8 pages & 5 figure

The Bimodal Galaxy Stellar Mass Function in the COSMOS Survey to z~1: A Steep Faint End and a New Galaxy Dichotomy

We present a new analysis of stellar mass functions (MF) in the COSMOS field to fainter limits than has been previously probed to z~1. Neither the total nor the passive or star-forming MF can be well fit with a single Schechter function once one probes below 3e9 Msun. We observe a dip or plateau at masses ~1e10 Msun, and an upturn towards a steep faint-end slope of -1.7 at lower mass at any z<1. This bimodal nature of the MF is not solely a result of the blue/red dichotomy. The blue MF is by itself bimodal at z~1. This suggests a new dichotomy in galaxy formation that predates the appearance of the red sequence. We propose two interpretations for this bimodality. If the gas fraction increases towards lower mass, galaxies with M_baryon~1e10 Msun would shift to lower stellar masses, creating the observed dip. This would indicate a change in star formation efficiency, perhaps linked to supernovae feedback becoming much more efficient. Therefore, we investigate whether the dip is present in the baryonic (stars+gas) MF. Alternatively, the dip could be created by an enhancement of the galaxy assembly rate at ~1e11 Msun, a phenomenon that naturally arises if the baryon fraction peaks at M_halo ~1e12 Msun. In this scenario, galaxies occupying the bump around M* would be identified with central galaxies and the second fainter component having a steep faint-end slope with satellites. While the dip is apparent in the total MF at any z, it appears to shift from the blue to red population, likely as a result of transforming high-mass blue galaxies into red ones. At the same time, we detect a drastic upturn in the number of low-mass red galaxies. Their increase with time reflects a decrease in the number of blue systems and so we tentatively associate them with satellite dwarf galaxies that have undergone quenching.Comment: 16 pages, 10 figures, accepted for publication in Ap

HI Observations of the Ca II absorbing galaxies Mrk 1456 and SDSS J211701.26-002633.7

In an effort to study Damped Lyman Alpha galaxies at low redshift, we have been using the Sloan Digital Sky Survey to identify galaxies projected onto QSO sightlines and to characterize their optical properties. For low redshift galaxies, the HI 21cm emission line can be used as an alternate tool for identifying possible DLA galaxies, since HI emitting galaxies typically exhibit HI columns that are larger than the classical DLA limit. Here we report on follow-up HI 21 cm emission line observations of two DLA candidates that are both low-redshift spiral galaxies, Mrk 1456 and SDSS J211701.26-002633.7. The observations were made using the Green Bank and Arecibo Telescopes, respectively. Analysis of their HI properties reveal the galaxies to be about one and two M_HI* galaxies, respectively, and to have average HI mass, gas-richness, and gas mass fraction for their morphological types. We consider Mrk 1456 and SDSS J211701.26-002633.7 to be candidate DLA systems based upon the strength of the CaII absorption lines they cause in their QSO's spectra, and impact parameters to the QSO that are smaller than the stellar disk. Compared to the small numbers of other HI-detected DLA and candidate DLA galaxies, Mrk 1456 and SDSS J211701.26-002633.7 have high HI masses. When compared with the expected properties of low-z DLAs from an HI-detected sample of galaxies, Mrk 1456 and SDSS J211701.26-002633.7 fall within the ranges for impact parameter and B-band absolute magnitude; and the HI mass distribution for the HI-detected DLAs agrees with that of the expected HI mass distribution for low-z DLAs. Our observations support galaxy-evolution models in which high mass galaxies make up an increasing contribution to the DLA cross-section at lower redshifts. [abridged]Comment: 12 pages, 5 figures, 5 tables; to be published in The Astronomical Journa