11 research outputs found
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
- Author
- Abdel-Aziz AK
- Abdelfatah S
- Abdellatif M
- Abdoli A
- Abel S
- Abeliovich H
- Abildgaard MH
- Abudu YP
- Acevedo-Arozena A
- Adamopoulos IE
- Adeli K
- Adolph TE
- Adornetto A
- Aflaki E
- Agam G
- Agarwal A
- Aggarwal BB
- Agnello M
- Agostinis P
- Agrewala JN
- Agrotis A
- Aguilar PV
- Ahmad ST
- Ahmed ZM
- Ahumada-Castro U
- Aits S
- Aizawa S
- Akkoc Y
- Akoumianaki T
- Akpinar HA
- Al-Abd AM
- Al-Akra L
- Al-Gharaibeh A
- Alaoui-Jamali MA
- Alberti S
- Alcocer-Gómez E
- Alessandri C
- Ali M
- Alim Al-Bari MA
- Aliwaini S
- Alizadeh J
- Almacellas E
- Almasan A
- Alonso A
- Alonso GD
- Altan-Bonnet N
- Altieri DC
- Alves da Costa C
- Alves S
- Alzaharna MM
- Amadio M
- Amantini C
- Amaral C
- Ambrosio S
- Amer AO
- Ammanathan V
- An Z
- Andersen SU
- Andrabi SA
- Andrade-Silva M
- Andres AM
- Angelini S
- Ann D
- Anozie UC
- Ansari MY
- Antas P
- Antebi A
- Antón Z
- Anwar T
- Apetoh L
- Apostolova N
- Araki T
- Araki Y
- Arasaki K
- Araya J
- Araújo WL
- Arden C
- Arguelles S
- Arias E
- Arikkath J
- Arimoto H
- Ariosa AR
- Armstrong-James D
- Arnauné-Pelloquin L
- Aroca A
- Arroyo DS
- Arsov I
- Artero R
- Arévalo M-A
- Asaro DML
- Aschner M
- Ashrafizadeh M
- Ashur-Fabian O
- Atanasov AG
- Au AK
- Auberger P
- Auner HW
- Aurelian L
- Autelli R
- Avagliano L
- Aveic S
- Aveleira CA
- Avin-Wittenberg T
- Aydin Y
- Ayton S
- Ayyadevara S
- Azzopardi M
- Baba M
- Backer JM
- Backues SK
- Bae D-H
- Bae O-N
- Bae SH
- Baehrecke EH
- Baek A
- Baek S-H
- Baek SH
- Bagetta G
- Bagniewska-Zadworna A
- Bai H
- Bai J
- Bai X
- Bai Y
- Bairagi N
- Baksi S
- Balazadeh S
- Balbi T
- Baldari CT
- Balduini W
- Ballabio A
- Ballester M
- Balzan R
- Bandopadhyay R
- Banerjee S
- Banerjee S
- Bao Y
- Baptista MS
- Baracca A
- Barbati C
- Bargiela A
- Barilà D
- Barlow PG
- Barmada SJ
- Barreiro E
- Barreto GE
- Bartek J
- Bartel B
- Bartolome A
- Barve GR
- Basagoudanavar SH
- Bassham DC
- Bast RC
- Basu A
- Batoko H
- Batten I
- Baulieu EE
- Baumgarner BL
- Bayry J
- Beale R
- Beau I
- Beaumatin F
- Bechara LRG
- Beck GR
- Beers MF
- Begun J
- Behl C
- Behrends C
- Behrens GMN
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- Bejarano E
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- Bellarosa C
- Belleudi F
- Bello-Morales R
- Belló Pérez M
- Beltran JSDO
- Beltran S
- Benbrook DM
- Bendorius M
- Benitez BA
- Benito-Cuesta I
- Bensalem J
- Berchtold MW
- Berezowska S
- Bergamaschi D
- Bergami M
- Bergmann A
- Berliocchi L
- Berlioz-Torrent C
- Bernard A
- Berthoux L
- Besirli CG
- Besteiro S
- Betin VM
- Beyaert R
- Bezbradica JS
- Bhaskar K
- Bhatia-Kissova I
- Bhattacharya R
- Bhattacharya S
- Bhattacharyya S
- Bhuiyan MS
- Bhutia SK
- Bi L
- Bi X
- Biden TJ
- Bijian K
- Billes VA
- Binart N
- Bincoletto C
- Birgisdottir AB
- Bjorkoy G
- Blanco G
- Blas-Garcia A
- Blasiak J
- Blomgran R
- Blomgren K
- Blum JS
- Boada-Romero E
- Boban M
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- Bonifacino JS
- Boone BA
- Bootman MD
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- Bornhauser BC
- Borthakur G
- Bosch J
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- Botas J
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- Boulton ME
- Bourdenx M
- Bourgeois B
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- Bousquet G
- Boya P
- Bozhkov PV
- Bozi LHM
- Bozkurt TO
- Brackney DE
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- Brandts CH
- Braun RJ
- Braus GH
- Bravo-Sagua R
- Bravo-San Pedro JM
- Brest P
- Bringer M-A
- Briones-Herrera A
- Broaddus VC
- Brodersen P
- Brodsky JL
- Brody SL
- Bronson PG
- Bronstein JM
- Brown CN
- Brown RE
- Brum PC
- Brumell JH
- Brunetti-Pierri N
- Bruno D
- Bryson-Richardson RJ
- Bucci C
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- Buchan JR
- Buchrieser C
- Buckingham EM
- Budak H
- Budini M
- Bueno M
- Buitrago-Molina LE
- Bultynck G
- Burada F
- Buraschi S
- Burgoyne JR
- Burón MI
- Bustos V
- Butturini E
- Byrd A
- Bánréti Á
- Büttner S
- Cabas I
- Cabrera-Benitez S
- Cadwell K
- Cai J
- Cai L
- Cai Q
- Cairó M
- Calbet JA
- Caldwell GA
- Caldwell KA
- Call JA
- Calvani R
- Calvo AC
- Calvo-Rubio Barrera M
- Camara NO
- Camonis JH
- Camougrand N
- Campanella M
- Campbell EM
- Campbell-Valois F-X
- Campello S
- Campesi I
- Campos JC
- Camuzard O
- Cancino J
- Candido de Almeida D
- Canesi L
- Caniggia I
- Canonico B
- Cantí C
- Cao B
- Caraglia M
- Caramés B
- Carchman EH
- Cardenal-Muñoz E
- Cardenas C
- Cardenas L
- Cardoso SM
- Carew JS
- Carle GF
- Carleton G
- Carloni S
- Carmona-Gutierrez D
- Carneiro LA
- Carnevali O
- Carosi JM
- Carra S
- Carrier A
- Carrier L
- Carroll B
- Carter AB
- Carvalho AN
- Casanova M
- Casas C
- Casas J
- Cassioli C
- Castillo EF
- Castillo K
- Castillo-Lluva S
- Castoldi F
- Castori M
- Castro AF
- Castro-Caldas M
- Castro-Hernandez J
- Castro-Obregon S
- Catz SD
- Cavadas C
- Cavaliere F
- Cavallini G
- Cavinato M
- Cayuela ML
- Cebollada Rica P
- Cecarini V
- Cecconi F
- Cechowska-Pasko M
- Cenci S
- Ceperuelo-Mallafré V
- Cerqueira JJ
- Cerutti JM
- Cervia D
- Cetintas VB
- Cetrullo S
- Chae H-J
- Chagin AS
- Chai C-Y
- Chakrabarti G
- Chakrabarti O
- Chakraborty T
- Chakraborty T
- Chami M
- Chamilos G
- Chan DW
- Chan ED
- Chan EYW
- Chan H
- Chan HH
- Chan HYE
- Chan MTV
- Chan YS
- Chandra PK
- Chang C
- Chang C-P
- Chang H-C
- Chang K
- Chao J
- Chapman T
- Charlet-Berguerand N
- Chatterjee S
- Chaube SK
- Chaudhary A
- Chauhan S
- Chaum E
- Checler F
- Cheetham ME
- Chen C-S
- Chen G-C
- Chen J-F
- Chen L
- Chen L
- Chen LL
- Chen M
- Chen M-K
- Chen N
- Chen Q
- Chen R-H
- Chen S
- Chen W
- Chen W
- Chen X
- Chen X-M
- Chen X-W
- Chen Y
- Chen Y
- Chen Y
- Chen Y-G
- Chen Y-J
- Chen Y-Q
- Chen Z
- Chen Z
- Chen Z
- Chen Z-H
- Chen ZJ
- Chen ZS
- Cheng H
- Cheng J
- Cheng S-Y
- Cheng W
- Cheng X
- Cheng X-T
- Cheng Y
- Cheng Z
- Cheong H
- Cheong JK
- Chernyak BV
- Cherry S
- Cheung CFR
- Cheung CHA
- Cheung K-H
- Chevet E
- Chi RJ
- Chiang AKS
- Chiaradonna F
- Chiarelli R
- Chiariello M
- Chica N
- Chiocca S
- Chiong M
- Chiou S-H
- Chiramel AI
- Chiurchiù V
- Cho D-H
- Choe S-K
- Choi AMK
- Choi ME
- Choudhury KR
- Chow NS
- Chu CT
- Chua JJE
- Chua JP
- Chung H
- Chung KP
- Chung S
- Chung S-H
- Chung Y-L
- Cianfanelli V
- Ciechomska IA
- Cifuentes M
- Cinque L
- Cirak S
- Cirone M
- Clague MJ
- Clarke R
- Clementi E
- Coccia EM
- Codogno P
- Cohen E
- Cohen MM
- Colasanti T
- Colasuonno F
- Colbert RA
- Colell A
- Coll NS
- Collins MO
- Colombo MI
- Colón-Ramos DA
- Combaret L
- Comincini S
- Cominetti MR
- Consiglio A
- Conte A
- Conti F
- Contu VR
- Cookson MR
- Coombs KM
- Coppens I
- Corasaniti MT
- Cordes N
- Corkery DP
- Cortese K
- Costa MDC
- Costantino S
- Costelli P
- Coto-Montes A
- Crack PJ
- Crespo JL
- Criollo A
- Crippa V
- Cristofani R
- Csizmadia T
- Cuadrado A
- Cui B
- Cui J
- Cui Y
- Cui Y
- Culetto E
- Cumino AC
- Cybulsky AV
- Czaja MJ
- Czuczwar SJ
- D'Adamo S
- D'Amelio M
- D'Arcangelo D
- D'Lugos AC
- D'Orazi G
- da Silva JA
- Dafsari HS
- Dagda RK
- Dagdas Y
- Daglia M
- Dai X
- Dai Y
- Dai Y
- Dal Col J
- Dalhaimer P
- Dalla Valle L
- Dallenga T
- Dalmasso G
- Damme M
- Dando I
- Dantuma NP
- Darling AL
- Das H
- Dasarathy S
- Dasari SK
- Dash S
- Daumke O
- Dauphinee AN
- Davies JS
- Davis RJ
- Davis T
- Dayalan Naidu S
- De Amicis F
- De Bosscher K
- De Felice F
- De Franceschi L
- De Leonibus C
- de Mattos Barbosa MG
- De Meyer GRY
- De Milito A
- De Nunzio C
- De Palma C
- De Santi M
- De Virgilio C
- De Zio D
- Debnath J
- DeBosch BJ
- Decuypere J-P
- Deehan MA
- Deflorian G
- DeGregori J
- Dehay B
- Del Rio G
- Delaney JR
- Delbridge LMD
- Delorme-Axford E
- Delpino MV
- Demarchi F
- Dembitz V
- Demers ND
- Deng H
- Deng Z
- Dengjel J
- Dent P
- Denton D
- DePamphilis ML
- Der CJ
- Deretic V
- Descoteaux A
- Devis L
- Devkota S
- Devuyst O
- Dewson G
- Dharmasivam M
- Dhiman R
- di Bernardo D
- Di Cristina M
- Di Domenico F
- Di Fazio P
- Di Fonzo A
- Di Guardo G
- Di Guglielmo GM
- Di Leo L
- Di Malta C
- Di Nardo A
- Di Rienzo M
- Di Sano F
- Diallinas G
- Diao J
- Diaz-Araya G
- Dickinson JM
- Diederich M
- Dieudé M
- Dikic I
- Ding S
- Ding W-X
- Dini L
- Dinic M
- Dinić J
- Dinkova-Kostova AT
- Dionne MS
- Distler JHW
- Diwan A
- Dixon IMC
- Djavaheri-Mergny M
- Dobrinski I
- Dobrovinskaya O
- Dobrowolski R
- Dobson RCJ
- Dokmeci Emre S
- Donadelli M
- Dong B
- Dong X
- Dong XC
- Dong Z
- Dorn Ii GW
- Dotsch V
- Dou H
- Dou J
- Dowaidar M
- Dridi S
- Drucker L
- du Toit A
- Du A
- Du C
- Du G
- Du H-N
- Du L-L
- Duan S-B
- Duan X
- Duarte SP
- Dubrovska A
- Dunlop EA
- Dupont N
- Durán RV
- Dwarakanath BS
- Dyshlovoy SA
- Dávila VA
- Díaz-Laviada I
- Ebrahimi-Fakhari D
- Eckhart L
- Edelstein CL
- Efferth T
- Eftekharpour E
- Eichinger L
- Eid N
- Eisenberg T
- Eissa NT
- Eissa S
- Ejarque M
- El Andaloussi A
- El-Hage N
- El-Naggar S
- El-Shafey ES
- Eleuteri AM
- Elgendy M
- Eliopoulos AG
- Elizalde MM
- Elks PM
- Elsasser H-P
- Elsherbiny ES
- Emerling BM
- Emre NCT
- Eng CH
- Engedal N
- Engelbrecht A-M
- Engelsen AST
- Enserink JM
- Escalante R
- Esclatine A
- Escobar-Henriques M
- Eskelinen E-L
- Espert L
- Eusebio M-O
- Fabrias G
- Fabrizi C
- Facchiano A
- Facchiano F
- Fadeel B
- Fader C
- Faesen AC
- Fairlie WD
- Falcó A
- Falkenburger BH
- Fan D
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- Fang EF
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- Farfel-Becker T
- Faure M
- Fazeli G
- Fedele AO
- Feldman AM
- Feng D
- Feng J
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- Ferguson TA
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- Fernie AR
- Fernández ÁF
- Fernández-Veledo S
- Ferrante AW
- Ferraresi A
- Ferrari MF
- Ferreira JCB
- Ferro-Novick S
- Figueras A
- Filadi R
- Filigheddu N
- Filippi-Chiela E
- Filomeni G
- Fimia GM
- Fineschi V
- Finetti F
- Finkbeiner S
- Fisher EA
- Fisher PB
- Flamigni F
- Fliesler SJ
- Flo TH
- Florance I
- Florey O
- Florio T
- Fodor E
- Follo C
- Fon EA
- Forlino A
- Fornai F
- Fortini P
- Fracassi A
- Fraldi A
- Franco B
- Franco R
- Franconi F
- Frankel LB
- Friedman SL
- Fröhlich LF
- Frühbeck G
- Fuentes JM
- Fujiki Y
- Fujita N
- Fujiwara Y
- Fukuda M
- Fulda S
- Furic L
- Furuya N
- Fusco C
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- Galasso A
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- Garg AD
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- Gentle IE
- Gerbino V
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- Goldstone DC
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- Hooper LV
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- Hubner CA
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- Hyung-Ryong Kim
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- Jimenez-Sanchez M
- Jin E-J
- Jin F
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- Jo E-K
- Joffre C
- Johansen T
- Johnson GVW
- Johnston SA
- Jokitalo E
- Jolly MK
- Joosten LAB
- Jordan J
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- Ju D
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- Judith D
- Juhász G
- Jun Y
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- Kaludercic N
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- Kaminskyy VO
- Kanamori H
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- Kanthasamy A
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- Kapuy O
- Karamouzis MV
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- Kaufmann SHE
- Kauppinen A
- Kaushal GP
- Kaushik S
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- Keating DJ
- Keber U
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- Keller CW
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- Kenchappa CS
- Kenific CM
- Kepp O
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- Kern A
- Ketteler R
- Keulers TG
- Khalfin B
- Khalil H
- Khambu B
- Khan SY
- Khandelwal VKM
- Khandia R
- Kho W
- Khobrekar NV
- Khuansuwan S
- Khundadze M
- Killackey SA
- Kim D
- Kim D-E
- Kim D-H
- Kim DR
- Kim E-K
- Kim EY
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- Zhang X-W
- Zhang XD
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- Zhang Y-D
- Zhang Y-Y
- Zhang Z
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- Zhong Q
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- Zhu B
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- Zhu G-Q
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- Zhu W-G
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- Zhuang H
- Zhuang X
- Zientara-Rytter K
- Zimmermann CM
- Ziviani E
- Zoladek T
- Zong W-X
- Zorov DB
- Zorzano A
- Zou W
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- Zou Z
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- Zwerschke W
- Álvarez ÉMC
- Ávalos Y
- Önal G
- Üstün S
- Čolić M
- Đokić J
- Žerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
Soluble epoxide hydrolase inhibitor, TPPU, increases regulatory T cells pathway in an arthritis model
- Author
- Bruce D. Hammock
- Carlos A. Trindade‐da‐Silva
- Carlos Ueira‐Vieira
- Carregaro V
- Chen Z
- Christophe Morisseau
- Dinarello CA
- Dong R
- Faulkner J
- Henrique B. Abdalla
- Juliana T. Clemente‐Napimoga
- Köhler BM
- Marcelo H. Napimoga
- McReynolds CB
- Park B
- Rose TE
- Ruiz‐Miyazawa KW
- Sergio Marcolino Rosa
- Staurengo‐Ferrari L
- Tu R
- Victor Angelo Martins Montalli
- Waldiceu A. Verri
- Yu Q
- Publication venue
- 'FASEB'
- Publication date
- Field of study
Vinpocetine regulates levels of circulating TLRs in Parkinson’s disease patients
- Author
- A Bolner
- C Comi
- C Kim
- C Noelker
- CC Filgueiras
- CK Fan
- EJ Downer
- F Shephard
- G Cappellano
- G Szilágyi
- GA Smith
- I Hindmarch
- I Thomas
- J Zhao
- K Kalinderi
- K McCabe
- KH Banner
- KI Jeon
- KW Ruiz-Miyazawa
- L Fellner
- L Zhang
- LF Clark
- M Nishimura
- N Dzamko
- N Stallard
- P Manza
- P Molnár
- S Gupta
- S Patyar
- SG Daniele
- SG Dastidar
- Shao Liang
- TN Tombaugh
- Wu Xiaomu
- Xie Xufang
- Y Ouchi
- YC Wang
- YR Wu
- Zhang Ping
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
The roles of small‐molecule inflammatory mediators in rheumatoid arthritis
- Author
- Bhatt S
- Brodie MJ
- Carregaro V
- Caselli G
- Chan MM
- Chen K
- Chen M
- Chu Y
- Duffin R
- Dufton N
- Egan KM
- Fechtner S
- Ferrante E
- Hashimoto A
- Honda T
- Huaxiang Wu
- Hyland IK
- Kim N
- Law ST
- Li J
- Mateen S
- Meng J
- Meng Y
- Murata T
- Peters‐Golden M
- Qi Cheng
- Ruiz‐Miyazawa KW
- Sena LA
- Seymour M
- Smolen JS
- Svetlov SI
- Vergne P
- Wang KC
- Wang MJ
- Wang Y
- Weinblatt ME
- Xu M
- Yan Du
- Yokomizo T
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Sublingual indocyanine green films for non-invasive swallowing assessment and inflammation detection through NIR/SWIR optical imaging
- Author
- A Dahan
- A De Gasperi
- A Ghodadra
- A Kadl
- A Suganami
- A-K Kirchherr
- AO Beringhs
- BE Schaafsma
- BK Byrd
- CS Shemesh
- D Eek
- DKF Meijer
- EM Sevick-Muraca
- F Laffleur
- FP Navarro
- GL Amidon
- H Igarashi
- H Kraan
- H Wen
- H-J Yoon
- IL Calil
- JA Carr
- JAS Moreno
- JF Jin
- JJ Vos
- JT Alander
- KD Stewart
- KW Ruiz-Miyazawa
- L Boni
- M Koland
- M-T Sheu
- MA Mohammed
- P Shekhawat
- PW Wertz
- R Bhavane
- R Maheshwari
- S Bhatnagar
- S Diao
- T Toyota
- TH Kim
- V Mundra
- W Song
- YG Guo
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Translocation Associated Membrane Protein 1 Contributes to Chronic Constriction Injury-Induced Neuropathic Pain in the Dorsal Root Ganglion and Spinal Cord in Rats
- Author
- B Yuan
- Bingbing Fan
- CJ Guo
- CJ Woolf
- CL Ng
- D Guo
- Dekun Yin
- F Xu
- H Mizoguchi
- H Wang
- Hyoungsub Lim
- JC Kagan
- KW Ruiz-Miyazawa
- L Basso
- L Fu
- M Costigan
- M Richter
- M Zimmermann
- MR Palhares
- N Gong
- R Li
- R Pan
- Rongxiang Lu
- S Akira
- S Chen
- S Xu
- Shunxing Zhu
- SR Chaplan
- V Nizet
- W Guo
- WJ Xin
- X Wang
- X Zhu
- Xingguo Xu
- XW Meng
- Y Kawasaki
- Y Okutsu
- Y Piao
- Y Zhao
- Y Zhou
- YH Gao
- Yonglin Chen
- Zhongling Xu
- ZY Guo
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Anti-inflammatory and anti-hyperalgesic effects of milnacipran in inflamed rats: involvement of myeloperoxidase activity, cytokines and oxidative/nitrosative stress
- Author
- A Hosseini
- A Kheradmand
- A Kheradmand
- AK Varghese
- B Sharma
- CJ Morris
- D Bilici
- D Kadetoff
- D Namgyal
- E Berrocoso
- G Littlejohn
- H Suarez-Roca
- H-J Hwang
- I Rodriguez-Pintó
- I Yaron
- J Bavill
- J Buritova
- J Guay
- JA Mico
- K Brune
- KW Ruiz-Miyazawa
- L Bach-Rojecky
- L Menendez
- L Neeb
- L Rafiee
- LE Hammody
- M Sayyah
- M Taler
- M Tsuruoka
- MJ Sammons
- MM Khattab
- N Yang
- P Dharmshaktu
- P Rao
- R Haddadi
- R Haddadi
- RJ Tynan
- RL Handy
- S Derry
- SA Schug
- SS Mizokami
- T King
- T Luedde
- TL Yaksh
- TS Fröde
- V Stejskal
- Y-J Surh
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Quercetin Inhibits Peripheral and Spinal Cord Nociceptive Mechanisms to Reduce Intense Acute Swimming-Induced Muscle Pain in Mice
- Author
- A Diaz-Ruiz
- A Faria
- A Oeckinghaus
- AC Zarpelon
- Allan J. C. Bussmann
- AW Filho
- C Calixto-Campos
- C Gao
- CC Hsu
- CF Guazelli
- D Wang
- DA Valerio
- DC Nieman
- DC Nieman
- Doumit Camilios-Neto
- FA Pinho-Ribeiro
- Felipe A. Pinho-Ribeiro
- FT Vicentini
- G Askari
- G Testa
- GR Souza
- J Huang
- JG Schiavuzzo
- Josiane A. Vignoli
- JS Kang
- JW Grau
- K Cheung
- KS O'Fallon
- KW Ruiz-Miyazawa
- LH Faccioli
- LS Cleto
- M Akram
- M Anjaneyulu
- M Chacur
- M Jang
- M Kiyomoto
- M Konrad
- MI Azevedo
- MJ Seo
- MS Hohmann
- N Parameswaran
- NA Maioli
- P Ramyaa
- PK Bagul
- R Marina
- RP Guedes
- Rubia Casagrande
- S Ghosh
- S Murase
- S Nakao
- S Tenschert
- Sergio M. Borghi
- Shao-Jun Tang
- SK Powers
- SM Borghi
- SM Borghi
- SM Borghi
- SR McAnulty
- T Graven-Nielsen
- T Yang
- TJ Hawke
- TM Cunha
- TT Carvalho
- V Fattori
- Victor Fattori
- W Wiczkowski
- WA Verri Jr
- WA Verri Jr
- Waldiceu A. Verri
- XD Liu
- XL Chen
- XR Xu
- Y Ding
- Y Li
- YJ Gao
- YJ Zhao
- YX Wang
- Z Gao
- ZQ Wang
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Nutritional and additive uses of chitin and chitosan in the food industry
- Author
- A Di Martino
- A Einbu
- A Einbu
- A Kędzia
- A Percot
- A Razdan
- A Sahebkar
- AAE Ibrahim
- AH Liao
- AJ Borderías
- AJ Winkler
- AJM Al-Fartosy
- AK Khare
- ANMA Fadel El-Seed
- AR Madureira
- AS Civille
- AS El-Sisi
- AS Szczesniak
- B He
- BC Fines
- BK Choi
- C Mannozzi
- C Tan
- C Xie
- CA Emerling
- CM Zhang
- CMP Yoshida
- CY Chiu
- D Colangelo
- D Kadam
- D Kulig
- D Qu
- DS do Amaral
- E Ansarifar
- E Atay
- E Gür
- E Ringø
- E Tabata
- ER Oliveira
- F Bonilla
- F Gassara
- F Oz
- G Margheri
- G McKay
- G Spagna
- GB Celli
- GI Harisa
- GP Cardoso
- GW Gooday
- H Sato
- H Zhang
- HE Bays
- HW Chang
- I Dammak
- I Dammak
- I Furda
- I Mateos-Aparicio
- IC Gonçalves
- J Ge
- J Li
- J Nie
- J Xiao
- JK Rutz
- K Azuma
- K Gopalan Nair
- K Halász
- K Kurita
- K Kurita
- K Kurita
- K Li
- K Pohkis
- KC Jeong
- KV Jardim
- KW Ho
- L Al-Anati
- L Engstrand
- L Huang
- L Rao
- LF Del Blanco
- M Arif
- M Bajaj
- M Carocho
- M Dash
- M De Falco
- M Elleuch
- M Espinal-Ruiz
- M Fernandes
- M Han
- M Hayes
- M Mengíbar
- M Peter
- M Rinaudo
- M Rizzo
- M Sansano
- M Sansano
- MC Gerards
- MNV Ravi Kumar
- MQ Wang
- MS Rodrı́guez
- N Dahiya
- N Martins
- N Miyazawa
- N Panith
- NA Qinna
- NV Sota-Peralta
- P Cao
- P Kumar
- P Labrude
- PA Sandford
- PC Schulz
- PG De Paiva
- Q Jin
- QP Li
- RD Mingoti
- RO Budkevich
- RV Rios
- S Banerjee
- S Chatterjee
- S Hirano
- S Khempaka
- S Quintela
- S Roller
- S Swiatkiewicz
- S Swiatkiewicz
- S Vincenzi
- SH Chang
- SM Bahijri
- SP Campana-Filho
- SS Choi
- TA Del Valle
- TS Vo
- TS Yang
- U Cornelli
- V Sieber
- W Wang
- W Zhang
- WW Mwangi
- X Li
- Y Dong
- Y Gong
- Y Kikkawa
- Y Lin
- Y Maezaki
- Y Noishiki
- Y Wang
- Y Xu
- Y Yuan
- Y Zhang
- Y-W Cho
- YJ Jeon
- Z Fang
- Z Jing
- Z Jing
- Z Wei
- Ö Taştan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 24/01/2020
- Field of study
Chitin is the first polysaccharide identified by man. Chitin and its numerous oligomeric and monomeric, acetylated or deacetylated derivates have many physiological functions and applications. Chitin is found in the cuticles of arthropods and is a major constituent of cell walls from fungal, yeast and algae, from where chitin can be extracted chemically, enzymatically or by fermentation. The principal sources of chitin and chitosan are actually crustacean shells. Worldwide, more than 13.000.000 tons of crustaceans are caught from marine habitats each year, thus generating huge amounts of food waste. The unique biodegradability, biorenewability, biocompatibility, physiological inertness and hydrophilicity of chitin and chitosan make them of high interest for research and industry.
In this chapter, we review the use of chitin, chitosan and their oligomers and monomers as food additives. In particular, their use in the regulation of lipid digestion and hypocholesterolemia, their functioning as an antigastritic agent and prebiotic is highlighted. Literature shows that oligomerization and the degree of deacetylation influences the development of chitin/chitosan-based nutraceuticals. The absence of chitinases and chitosanases in the human gut renders those biopolymers resistant to even partial degradation. For food applications, they are used as emulsifying, fining, thickening and stabilizing agents, antioxidants, and low calories food mimetics
Mapping the human genetic architecture of COVID-19
- Author
- Abdelrazik M
- Abdullah T
- Abe R
- Abe S
- Abecasis GR
- Abel L
- Abernathy C
- Abraheem A
- Abul-Husn NS
- Acosta-Herrera M
- Acquilini D
- Acquilini D
- Adachi T
- Adachi Y
- Adams C
- Adams K
- Adanini O
- Adeleye O
- Adeniji K
- Adra D
- Afifi N
- Afilalo J
- Afilalo M
- Afolabi D
- Afrasiabi Z
- Afset JE
- Agasou A
- Aghemo A
- Agranoff D
- Agrawal S
- Aguirre LA
- Agwuh K
- Ahmad HF
- Ahmad N
- Ahmed A
- Ahmed C
- Ahmed KA
- Ai M
- Ail D
- Akeroyd L
- Akhtar MN
- Akhtar S
- Akinkugbe O
- Aksentijevich A
- Al Thani A
- Al-Muftah W
- Al-Sarraj Y
- Alarcon C
- Alarcon-Riquelme ME
- Alasdair F
- Alaverdian D
- Alavere H
- Albertos R
- Albillos A
- Albrecht W
- Albrich W
- Albrich WC
- Aldera EL
- Aldridge J
- Alegria A
- Alex B
- Alexander P
- Alfonso J
- Algera AG
- Ali A
- Ali IMA
- Ali S
- Aliberti S
- Allan A
- Allan E
- Allan J
- Alldis Z
- Allen L
- Allen S
- Allibone S
- Allison KS
- Allos R
- Ally SM
- Almaden-Boyle C
- Altabaibeh A
- Altmueller J
- Alvaro A
- Amar D
- Amin V
- Amitrano S
- Amiya S
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- Cossarizza A
- Costantino G
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- Coton Z
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- de Gordoa LO-R
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- De la Horra C
- De Neef M
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- de Rojas I
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- zu Bentrup FM
- Zucchi P
- Zwinderman AHK
- Zyndorf M
- Publication venue
- Publication date
- 01/01/2021
- Field of study
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors have a role in the chance of exposure to SARS-CoV-2 and the severity of COVID-191,2, host genetics may also be important. Identifying host-specific genetic factors may reveal biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed a global network of researchers to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity. Here we describe the results of three genome-wide association meta-analyses that consist of up to 49,562 patients with COVID-19 from 46 studies across 19 countries. We report 13 genome-wide significant loci that are associated with SARS-CoV-2 infection or severe manifestations of COVID-19. Several of these loci correspond to previously documented associations to lung or autoimmune and inflammatory diseases3,4,5,6,7. They also represent potentially actionable mechanisms in response to infection. Mendelian randomization analyses support a causal role for smoking and body-mass index for severe COVID-19 although not for type II diabetes. The identification of novel host genetic factors associated with COVID-19 was made possible by the community of human genetics researchers coming together to prioritize the sharing of data, results, resources and analytical frameworks. This working model of international collaboration underscores what is possible for future genetic discoveries in emerging pandemics, or indeed for any complex human disease