79 research outputs found
Anomalous rotational properties of Bose-Einstein condensates in asymmetric traps
We study the rotational properties of a Bose-Einstein condensate confined in
a rotating harmonic trap for different trap anisotropies. Using simple
arguments, we derive expressions for the velocity field of the quantum fluid
for condensates with or without vortices. While the condensed gas describes
open spiraling trajectories, on the frame of reference of the rotating trap the
motion of the fluid is against the trap rotation. We also find explicit
formulae for the angular momentum and a linear and Thomas-Fermi solutions for
the state without vortices. In these two limits we also find an analytic
relation between the shape of the cloud and the rotation speed. The predictions
are supported by numerical simulations of the mean field Gross-Pitaevskii
model.Comment: 4 RevTeX pages, 2 EPS figures; typos fixed, reference adde
Stabilization and pumping of giant vortices in dilute Bose-Einstein condensates
Recently, it was shown that giant vortices with arbitrarily large quantum
numbers can possibly be created in dilute Bose-Einstein condensates by
cyclically pumping vorticity into the condensate. However, multiply quantized
vortices are typically dynamically unstable in harmonically trapped nonrotated
condensates, which poses a serious challenge to the vortex pump procedure. In
this theoretical study, we investigate how the giant vortices can be stabilized
by the application of a Gaussian potential peak along the vortex core. We find
that achieving dynamical stability is feasible up to high quantum numbers. To
demonstrate the efficiency of the stabilization method, we simulate the
adiabatic creation of an unsplit 20-quantum vortex with the vortex pump.Comment: 8 pages, 6 figures; to be published in J. Low Temp. Phys., online
publication available at http://dx.doi.org/10.1007/s10909-010-0216-
School-based prevention for adolescent Internet addiction: prevention is the key. A systematic literature review
Adolescentsâ media use represents a normative need for information, communication, recreation and functionality, yet problematic Internet use has increased. Given the arguably alarming prevalence rates worldwide and the increasingly problematic use of gaming and social media, the need for an integration of prevention efforts appears to be timely. The aim of this systematic literature review is (i) to identify school-based prevention programmes or protocols for Internet Addiction targeting adolescents within the school context and to examine the programmesâ effectiveness, and (ii) to highlight strengths, limitations, and best practices to inform the design of new initiatives, by capitalizing on these studiesâ recommendations. The findings of the reviewed studies to date presented mixed outcomes and are in need of further empirical evidence. The current review identified the following needs to be addressed in future designs to: (i) define the clinical status of Internet Addiction more precisely, (ii) use more current psychometrically robust assessment tools for the measurement of effectiveness (based on the most recent empirical developments), (iii) reconsider the main outcome of Internet time reduction as it appears to be problematic, (iv) build methodologically sound evidence-based prevention programmes, (v) focus on skill enhancement and the use of protective and harm-reducing factors, and (vi) include IA as one of the risk behaviours in multi-risk behaviour interventions. These appear to be crucial factors in addressing future research designs and the formulation of new prevention initiatives. Validated findings could then inform promising strategies for IA and gaming prevention in public policy and education
Does the influence of peers and parents on adolescents' drunkenness differ between Roma and non-Roma adolescents in Slovakia?
Proceedings of the 2016 Childhood Arthritis and Rheumatology Research Alliance (CARRA) Scientific Meeting
Novel Loci for Adiponectin Levels and Their Influence on Type 2 Diabetes and Metabolic Traits : A Multi-Ethnic Meta-Analysis of 45,891 Individuals
J. Kaprio, S. Ripatti ja M.-L. Lokki työryhmien jÀseniÀ.Peer reviewe
Whole-genome sequencing reveals host factors underlying critical COVID-19
Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care1 or hospitalization2,3,4 after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genesâincluding reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)âin critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease
Quality of Life in Predialysis End-Stage Renal Disease Patients at the Initiation of Dialysis Therapy
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