Disaggregating the electricity sector of china's input-output table for improved environmental life-cycle assessment

Missing process detail of sectors in Input-Output (I-O) tables has been pointed out as a limitation of I-O analysis in environmental-economic life cycle assessment. Aggregation of resource-intensive sectors decreases the accuracy of the results. Often, economic sectors are compiled in a more aggregated form than environmental satellite accounts, and as [Lenzen, M. (2011) Aggregation Versus Disaggregation in Input-Output Analysis of the Environment. Economic Systems Research, 23, 73-89] asserts, it is superior for environmental analysis to disaggregate the I-O table, even if only partial information exists for the disaggregation. In this paper we present a methodology to disaggregate the electricity sector of the Chinese national I-O table by using regional information and cost data for operation and maintenance of power plants. The electricity sector is disaggregated into a transmission and distribution sector as well as eight sub-sectors representing different types of technology in power plants (subcritical coal, hydro, etc.). The electricity consumption mix of each industry is determined by using regional industry presence and regional electricity power mixes. The disaggregated I-O table offers refined results for calculating emissions embodied in international exports from China, a valuable contribution for estimating national greenhouse gases emissions inventories under the consumption-based approach for countries that rely heavily on imports of goods from China

The Use of a Scenario-Based Nominal Group Technique to Assess P/CVE Programs: Development and Pilot Testing of a Toolkit

Preventing and countering violent extremism (P/CVE) requires coordination among multiple agencies, stakeholders and systems. The complexity of this task (compounded by the variety of P/CVE programming around the world) creates a  challenge for those hoping to develop these initiatives. The purpose of this project was to develop a replicable process and corresponding toolkit to engage multiple stakeholders in consensus building around the efficacy and improvement of nascent, developing or mature systems-level P/CVE programs. As a method, we adapted the process of nominal group technique (NGT), a structured-brainstorming tool that provides an orderly procedure for obtaining qualitative and ranked information from heterogenous participant pools. The technique we developed is based on a case-study approach (“scenario”) which we then tested in three countries (USA, Sweden, and North Macedonia) with existing P/CVE initiatives at different stages of development. We conducted scenario-based NGT sessions in each location and then systematically analyzed the results using iterative qualitative coding based on a common framework. Results were analyzed to achieve consensus on the most common system-level challenges and system-level functions, necessary to overcome those challenges, in each location. Practitioners in each local jurisdiction were then able to utilize the results derived from the NGT for their own purposes, such as advocacy to policy makers, strategic regional P/CVE planning, and ongoing stakeholder engagement. Acknowledgments: This project was funded by the NATO Science for Peace and Security Programme under the award entitled "Evaluation Support for CVE at the Local Level" SPS.MYPG5556, the Swedish Contingency Agency (MSB), and the U.S. Department of Homeland Security (DHS), Science and Technology Directorate (Cooperative Agreement Number: 2015-ST-108-FRG005). The content of this manuscript as well as the views and discussions expressed are solely those of the authors and do not necessarily represent the official views of any of the above institutions, nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. government

From Military to Healthcare: Adopting and Expanding Ethical Principles for Generative Artificial Intelligence

In 2020, the U.S. Department of Defense officially disclosed a set of ethical principles to guide the use of Artificial Intelligence (AI) technologies on future battlefields. Despite stark differences, there are core similarities between the military and medical service. Warriors on battlefields often face life-altering circumstances that require quick decision-making. Medical providers experience similar challenges in a rapidly changing healthcare environment, such as in the emergency department or during surgery treating a life-threatening condition. Generative AI, an emerging technology designed to efficiently generate valuable information, holds great promise. As computing power becomes more accessible and the abundance of health data, such as electronic health records, electrocardiograms, and medical images, increases, it is inevitable that healthcare will be revolutionized by this technology. Recently, generative AI has captivated the research community, leading to debates about its application in healthcare, mainly due to concerns about transparency and related issues. Meanwhile, concerns about the potential exacerbation of health disparities due to modeling biases have raised notable ethical concerns regarding the use of this technology in healthcare. However, the ethical principles for generative AI in healthcare have been understudied, and decision-makers often fail to consider the significance of generative AI. In this paper, we propose GREAT PLEA ethical principles, encompassing governance, reliability, equity, accountability, traceability, privacy, lawfulness, empathy, and autonomy, for generative AI in healthcare. We aim to proactively address the ethical dilemmas and challenges posed by the integration of generative AI in healthcare

Recent AEM Case Study Examples of a Full Waveform Time-Domain System for Near-Surface and Groundwater Applications

Early time or high frequency airborne electromagnetic data (AEM) are desirable for shallow sounding or mapping of resistive areas but this poses difficulties due to a variety of issues, such as system bandwidth, system calibration and parasitic loop capacitance. In an effort to address this issue, a continued system design strategy, aimed at improving its early-channel VTEM data, has achieved fully calibrated, quantitative measurements closer to the transmitter current turn-off, while maintaining reasonably optimal deep penetration characteristics. The new design implementation, known as “Full Waveform” VTEM was previously described by Legault et al. (2012). This paper presents some case-study examples of a Full Waveform helicopter time-domain EM system for near-surface application

Le processus d’institutionnalisation du commerce équitable

Texte de la communication présentée au 3e Colloque international sur le commerce équitable, mai 2008, Montpelier, FranceComme toute innovation sociale, le commerce équitable (CÉ) est confronté au défi de son institutionnalisation sans que soit dénaturé son idée initiale (introduction). L’analyse de la trajectoire du CÉ permet de rendre compte de son processus d’institutionnalisation et des stratégies adoptées par les organisations du commerce équitable face au risque de dénaturation (partie 1). Le processus d’institutionnalisation est traversé par des tensions autour d’enjeux, lesquelles appartiennent à trois grandes familles de tensions (partie 2). À chaque famille de tension correspond un microprocessus de gestion de la tension auquel les acteurs ont recours face aux tendances qui tirent le CÉ trop loin de son projet initial. Mais force est aussi de reconnaître qu’il existe un double processus de réinvention de l’innovation et de reconfiguration institutionnelle (conclusion).As every social innovation, Fair Trade faces the challenge of institutionalization without altering its initial idea (introduction). The analysis of the trajectory of the Fair Trade movement reveals the process of institutionalization and the strategies adopted by organizations to prevent the risks of alteration and dilution (part one). The process of institutionalization is subject to multiple tensions around the issues at stake, which can be aggregated into three broad families of tensions (part two). Each family of tensions corresponds to a micro-process of tension management that can be used by actors and stakeholders to control forces pulling the Fair Trade movement too far away from its initial project. These frameworks of analysis instruct us on the double process at play, where the innovation’s re-invention meets the institutional reconfiguration (conclusion)

Physical activity to improve cognition in older adults: can physical activity programs enriched with cognitive challenges enhance the effects? A systematic review and meta-analysis

: EPHPP quality rating scores (DOCX 38 kb

Cocaine Serves as a Peripheral Interoceptive Conditioned Stimulus for Central Glutamate and Dopamine Release

Intravenous injections of cocaine HCl are habit-forming because, among their many actions, they elevate extracellular dopamine levels in the terminal fields of the mesocorticolimbic dopamine system. This action, thought to be very important for cocaine's strong addiction liability, is believed to have very short latency and is assumed to reflect rapid brain entry and pharmacokinetics of the drug. However, while intravenous cocaine HCl has almost immediate effects on behavior and extracellular dopamine levels, recent evidence suggests that its central pharmacological effects are not evident until 10 or more seconds after IV injection. Thus the immediate effects of a given intravenous cocaine injection on extracellular dopamine concentration and behavior appear to occur before there is sufficient time for cocaine to act centrally as a dopamine uptake inhibitor. To explore the contribution of peripheral effects of cocaine to the early activation of the dopamine system, we used brain microdialysis to measure the effects of cocaine methiodide (MI)—a cocaine analogue that does not cross the blood brain barrier—on glutamate (excitatory) input to the dopamine cells. IP injections of cocaine MI were ineffective in cocaine-naïve animals but stimulated ventral tegmental glutamate release in rats previously trained to lever-press for cocaine HCl. This peripherally triggered glutamate input was sufficient to reinstate cocaine-seeking in previously trained animals that had undergone extinction of the habit. These findings offer an explanation for short-latency behavioral responses and immediate dopamine elevations seen following cocaine injections in cocaine-experienced but not cocaine-naïve animals

Quick and Simple Detection Technique to Assess the Binding of Antimicrotubule Agents to the Colchicine-Binding Site

Development of antimitotic binding to the colchicine-binding site for the treatment of cancer is rapidly expanding. Numerous antimicrotubule agents are prepared every year, and the determination of their binding affinity to tubulin requires the use of purified tubulins and radiolabeled ligands. Such a procedure is costly and time-consuming and therefore is limited to the most promising candidates. Here, we report a quick and inexpensive method that requires only usual laboratory resources to assess the binding of antimicrotubules to colchicine-binding site. The method is based on the ability of N,N'-ethylene-bis(iodoacetamide) (EBI) to crosslink in living cells the cysteine residues at position 239 and 354 of β-tubulin, residues which are involved in the colchicine-binding site. The β-tubulin adduct formed by EBI is easily detectable by Western blot as a second immunoreacting band of β-tubulin that migrates faster than β-tubulin. The occupancy of colchicine-binding site by pertinent antimitotics inhibits the formation of the EBI: β-tubulin adduct, resulting in an assay that allows the screening of new molecules targeting this binding site

Kinetics Aspects of the Reversible Assembly of Copper in Heterometallic Mo3CuS4 Clusters with 4,4′-Di-tert-butyl-2,2′- bipyridine

Treatment of the triangular [Mo3S4Cl3(dbbpy)3]Cl cluster ([1]Cl) with CuCl produces a novel tetrametallic cuboidal cluster [Mo3(CuCl)S4Cl3(dbbpy)3][CuCl2] ([2][CuCl2]), whose crystal structure was determined by X-ray diffraction (dbbpy = 4,4′-di-tert-butyl-2,2′-bipyridine). This species, which contains two distinct types of Cu(I), is the first example of a diimine-functionalized heterometallic M3M′S4 cluster. Kinetics studies on both the formation of the cubane from the parent trinuclear cluster and its dissociation after treatment with halides, supported by NMR, electrospray ionization mass spectrometry, cyclic voltammetry, and density functional theory calculations, are provided. On the one hand, the results indicate that addition of Cu(I) to [1]+ is so fast that its kinetics can be monitored only by cryo-stopped flow at −85 °C. On the other hand, the release of the CuCl unit in [2]+ is also a fast process, which is unexpectedly assisted by the CuCl2 − counteranion in a process triggered by halide (X−) anions. The whole set of results provide a detailed picture of the assembly−disassembly processes in this kind of cluster. Interconversion between trinuclear M3S4 clusters and their heterometallic M3M′S4 derivatives can be a fast process occurring readily under the conditions employed during reactivity and catalytic studies, so their occurrence is a possibility that must be taken into account in future studies