Maximum approximate entropy and r threshold: A new approach for regularity changes detection

Approximate entropy (ApEn) has been widely used as an estimator of regularity in many scientific fields. It has proved to be a useful tool because of its ability to distinguish different system's dynamics when there is only available short-length noisy data. Incorrect parameter selection (embedding dimension $m$, threshold $r$ and data length $N$) and the presence of noise in the signal can undermine the ApEn discrimination capacity. In this work we show that $r_{max}$ ($ApEn(m,r_{max},N)=ApEn_{max}$) can also be used as a feature to discern between dynamics. Moreover, the combined use of $ApEn_{max}$ and $r_{max}$ allows a better discrimination capacity to be accomplished, even in the presence of noise. We conducted our studies using real physiological time series and simulated signals corresponding to both low- and high-dimensional systems. When $ApEn_{max}$ is incapable of discerning between different dynamics because of the noise presence, our results suggest that $r_{max}$ provides additional information that can be useful for classification purposes. Based on cross-validation tests, we conclude that, for short length noisy signals, the joint use of $ApEn_{max}$ and $r_{max}$ can significantly decrease the misclassification rate of a linear classifier in comparison with their isolated use

EL VALOR SIMBÓLICO DE LA IMAGEN REPRESENTADA

El objetivo de este artículo es analizar la importancia del valor simbólico de la imagen como representación del individuo y de la sociedad y cómo ésta se convierte en representación social de distintas épocas. El tema que se aborda es la comunicación a través de la imagen y el papel social de la misma. De aquí la importancia de poner en contexto algunos términos como el de imagen, cómo se convierte en representación social, y cómo éstas se vinculan con las formas de consumo de las sociedades, trasladando significados y valores a las mismas

La frontera como mecanismo de exclusión social

Para el caso latinoamericano, se ha hecho presente históricamente una diferenciación cultural que ha sobrepasado la diferenciación física que imponen de los límites territoriales, y ésta sienta sus bases en el mosaico multicultural que constituye al continente americano desde antes de la conquista. Tal diferenciación ha dado forma y estructura a la manera de mirar las distinciones, más que físicas y geográficas del territorio, las culturales, que han forjado a través del tiempo un sentido claro de pertenencia que caracteriza a cada nación. De acuerdo con Grimson,2 a lo largo de la historia se han desarrollado innumerables espacios sociales donde las diferencias sólo son producidas por la frontera y todo lo que ella implica: sistemas escolares, regimientos militares, medios de comunicación, ejercicio de un sistema político y económico que condiciona el funcionamiento mismo de esa frontera y posibilita las relaciones sociales. La frontera funge como instrumento mediador de las relaciones económicopolíticas cuyo reflejo se materializa en el resto de los sectores que integran el territorio.El estudio de las fronteras no se limita a las demarcaciones jurídicas que se establecen en la circunscripción de los Estados-Nación, entidades federativas o en el ámbito municipal. Es necesario tomar en cuenta otro tipo de conceptualización sobre ellas, como la simbólica, que establece las culturas, identidades, creencias, construcciones mentales o imaginarias. De ahí que resulte preponderante diferenciar los dos tipos de frontera más usuales, que se hacen presentes recurrentemente en el debate: por un lado las fronteras culturales, en las que se resaltan los aspectos identitarios y sentidos de pertenencia; y por otro, las fronteras jurídicas, que se vinculan más a los límites físicos con fuerte contenido simbólico, que determina el nacionalismo.Universidad Autónoma del Estado de México - CONACY

Progeny performance and pathogen attack relative to elevation in a neotropical tree

Climate and resource availability at the parent tree location are known to explain progeny characteristics; however, few studies have examined the role of resistance or tolerance to pathogens, even though climate is a main driver of pathogen abundance. We hypothesize that climate at the parent tree location has a relatively greater influence on progeny resistance or tolerance to pathogens than other progeny characteristics, such as seed mass or seedling growth. As a study species we used the vulnerable Neotropical tree Kageneckia lanceolata known to be susceptible to damping-off diseases. We collected seeds from 60 trees along the species entire elevational gradient in central Argentina as a surrogate for climatic gradient and selected an ample array of parent tree sizes and rockiness under the crown as surrogate of tree access to resources. Seedling survival in a common nursery significantly increased with elevation of the parent tree from 40 to 80 % (P 0.05). Parent tree size and rockiness were not related to any of the measured progeny characteristics. We conclude that the pathogenic environment around parental plants might have a great influence on progeny resistance or tolerance to pathogens and suggest that incorporating the pathogen dimension into future progeny studies may yield important findings.Fil: Renison, Daniel. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Centro de Ecología y Recursos Naturales Renovables; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Biológicas y Tecnológicas. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto de Investigaciones Biológicas y Tecnológicas; ArgentinaFil: Bergero, Hernán. Universidad Nacional de Córdoba; ArgentinaFil: Soteras, María Florencia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaFil: Herrero, María Lucrecia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Biológicas y Tecnológicas. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto de Investigaciones Biológicas y Tecnológicas; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Centro de Ecología y Recursos Naturales Renovables; ArgentinaFil: Rodriguez, Juan Manuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Biológicas y Tecnológicas. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto de Investigaciones Biológicas y Tecnológicas; Argentina. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Centro de Ecología y Recursos Naturales Renovables; ArgentinaFil: Torres, Romina Cecilia. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Centro de Ecología y Recursos Naturales Renovables; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones Biológicas y Tecnológicas. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Instituto de Investigaciones Biológicas y Tecnológicas; ArgentinaFil: Cingolani, Ana María. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaFil: Hensen, Isabell. Martin Luther University of Halle-Wittenberg; Alemani

Metal Accumulation by Jatropha curcas L. Adult Plants Grown on Heavy Metal-Contaminated Soil

Jatropha curcas has the ability to phytoextract high amounts of heavy metals during its first months just after seeding. Notwithstanding, there is scarce information about metal uptake by adult J. curcas plants. To shed light on this issue, 4-year-old J. curcas L. plants were planted in a soil mixture of peat moss and mining soil (high metals content), and the biomass growth and metal absorption during 90 days were compared with those of plants growing in peat moss. The main metal found in the mining soil was Fe (31985 mg kg-1) along with high amounts of As (23717 mg kg-1). After the 90-day phytoremediation, the plant removed 29% of Fe and 44% of As from the soil mixture. Results revealed that J. curcas L. translocated high amounts of metals to its aerial parts, so that translocation factors were much higher than 1. Because of the high translocation and bioaccumulation factors obtained, J. curcas L. can be regarded as a hyperaccumulator plant. Despite the great capacity of J. curcas L. to phytoremediate heavy-metal-contaminated soils, the main drawback is the subsequent handling of the metal-contaminated biomass, although some potential applications have been recently highlighted for this biomass.University of Seville (VIPPIT-2019-I.5

Análisis de las redes sociales mediante la visión de la comunidad educativa desde una perspectiva micropolítica

Reconocer el valor del establecimiento de redes colaborativas comunitarias en la actualidad se convierte en una necesidad y al mismo tiempo en una oportunidad para la mejora de las dinámicas de desarrollo de las organizaciones educativas. Pero, en muchas ocasiones, esos procesos colaborativos no son del todo transparentes y por ello, una visión micropolítica para su entendimiento y aprehensión parece oportuna. Este análisis consecuente puede ofrecer luces y advertir y considerar las sombras que puedan limitar los procesos innovadores y de mejora de nuestros centros educativos. Nuestro estudio es un ejemplo de ello a través de un proceso de investigación etnográfica

Creative assessment through eportfolios in Higher Education

Este artículo presenta los resultados de un proyecto de investigación docente sobre la validez del portafolios electrónico como técnica para formar y evaluar competencias. Se realizó durante el curso 2008-09 con 94 estudiantes de 4o de Pedagogía de la Universidad de Sevilla en la asignatura de Diseño de Programas de Orientación. La metodología de trabajo en la asignatura fue el aprendizaje basado en proyectos colaborativos. Las técnicas de investigación fueron un diario de campo del profesor que recogió el desarrollo, avances y dificultades de cada grupo de trabajo, así como un cuestionario al estudiante sobre la validez del e-portafolios respecto a la consecución y evaluación de las competencias. También se realizaron controles de revisión continua con cumplimentación de fichas de registro. Se emplearon el análisis de contenido y la triangulación de fuentes como técnicas para el análisis de datos. Los hallazgos nos permiten afirmar la validez de esta herramienta, no solo para evaluar aprendizajes, sino sobre todo para tutorizar sobre competencias. El uso del e-portafolios favorece los procesos de autorregulación del aprendizaje, de reflexión conjunta profesor-estudiante sobre las competencias trabajadas y reafirma el valor añadido en términos de desempeño sobre otras técnicas tradicionales de evaluación

Preclinical discovery of duloxetine for the treatment of depression

Introduction: Affective disorders, including major depressive disorder (MDD), are among the most severely disabling mental disorders, and in many cases areIntroduction: Affective disorders, including major depressive disorder (MDD), are among the most severely disabling mental disorders, and in many cases are associated with poor treatment outcomes. From the emergence of the monoamine hypothesis of depression, the first-line treatment for MDD had mainly acted by inhibiting monoamine reuptake, and thereby increasing these levels in the synaptic cleft. However, in recent years, several newantidepressant drugs have appeared, including duloxetine, a dual serotonin (5-HT) and noradrenaline (NA) reuptake inhibitor recommended for the treatment of MDD. Areas covered: The article reviews and discusses the biochemical and functional profile of duloxetine splitting the review into acute and long-term treatment with this dual monoamine reuptake inhibitor. In addition, the authors summarize available preclinical behavioral research data, which have demonstrated among other effects, the antidepressant-like activity of duloxetine in several animal models. The authors focus on the most recent literature on synaptic neuroplasticity modulation of this antidepressant drug. Finally, the authors briefly mention other approved indications of duloxetine. Expert opinion: Duloxetine inhibits 5-HT and NA reuptake, effectively desensitizes various autoreceptors and promotes neuroplasticity. Clinically, duloxetine is an effective antidepressant that is well tolerated and has significant efficacy in the treatment of MDD. associated with poor treatment outcomes. From the emergence of the monoamine hypothesis of depression, the first-line treatment for MDD had mainly acted by inhibiting monoamine reuptake, and thereby increasing these levels in the synaptic cleft. However, in recent years, several new antidepressant drugs have appeared, including duloxetine, a dual serotonin (5-HT) and noradrenaline (NA) reuptake inhibitor recommended for the treatment of MDD

Neurotrophins Role in Depression Neurobiology: A Review of Basic and Clinical Evidence

Depression is a neuropsychiatric disorder affecting a huge percentage of the active population especially in developed countries. Research has devoted much of its attention to this problematic and many drugs have been developed and are currently prescribed to treat this pathology. Yet, many patients are refractory to the available therapeutic drugs, which mainly act by increasing the levels of the monoamines serotonin and noradrenaline in the synaptic cleft. Even in the cases antidepressants are effective, it is usually observed a delay of a few weeks between the onset of treatment and remission of the clinical symptoms. Additionally, many of these patients who show remission with antidepressant therapy present a relapse of depression upon treatment cessation. Thus research has focused on other possible molecular targets, besides monoamines, underlying depression. Both basic and clinical evidence indicates that depression is associated with several structural and neurochemical changes where the levels of neurotrophins, particularly of brain-derived neurotrophic factor (BDNF), are altered. Antidepressants, as well as other therapeutic strategies, seem to restore these levels. Neuronal atrophy, mostly detected in limbic structures that regulate mood and cognition, like the hippocampus, is observed in depressed patients and in animal behavioural paradigms for depression. Moreover, chronic antidepressant treatment enhances adult hippocampal neurogenesis, supporting the notion that this event underlies antidepressants effects. Here we review some of the preclinical and clinical studies, aimed at disclosing the role of neurotrophins in the pathophysiological mechanisms of depression and the mode of action of antidepressants, which favour the neurotrophic/neurogenic hypothesis

Playful interaction for learning collaboratively and individually

Playful interactions facilitate the development of engaging applications for different purposes. This aspect is very important for serious games, and especially when these games are for children. Another aspect to consider is the interaction among children, which could be a great reinforcement in learning environments. Children enjoy playing, and they like playing with other children. This relationship could encourage their motivation and their learning outcomes. In this paper, a playful interaction system for learning about a period of history is presented. The interaction of the system was achieved using natural gestures and the visuali-zation was autostereoscopic. A study was carried out to determine whether their learning outcomes were greater playing collabo-ratively or playing individually. Forty six children from 7 to 10 years old participated in the study. The analysis of the pre-tests and the post-tests indicate that the children increased their knowledge about historical periods after playing with the two modes. Therefore, the game could be used as an effective transmitter of knowledge both collaboratively and individually. When the post-knowledge scores for the two modes were compared, statistically significant differences were found in favor of the collaborative mode. Therefore, the collaborative mode facilitates learning to a greater extent than the individual mode. The rest of the questions indicated that the children had a lot of fun while playing the game; they found the game easy to play; they would recommend the game to their friends; and they scored the game as a mean of 9.57 over 10. Finally, we believe that the combination of playful interaction and autostereoscopy is an option that should be exploited not only for the development of computer-supported learning systems, but also for the development of systems for different purposesThis work was funded by the Spanish APRENDRA project (TIN2009-14319-C02-01).Martín San José, JF.; Juan Lizandra, MC.; Torres, E.; Vicent López, MJ. (2014). Playful interaction for learning collaboratively and individually. Journal of Ambient Intelligence and Smart Environments. 6(3):295-311. https://doi.org/10.3233/AIS-140257S2953116