La inteligencia emocional en el profesorado de Educación Infantil y Primaria

Las emociones se presentan a lo largo de nuestra vida en diversos ámbitos, entre ellos la escuela. Desafortunadamente, ésta siempre ha dado más prioridad a los aspectos cognitivos frente a los emocionales del alumnado, lo cual se manifestaba en unos aprendizajes más técnicos y científicos. En la actualidad, la vinculación entre ambos es indudable. Por ello, la práctica educativa debe otorgar una atención especial a la educación emocional de modo que los alumnos adquieran las herramientas necesarias para enfrentarse a la vida. El planteamiento principal que tiene el trabajo es el de proyectar la importancia de una buena formación inicial y permanente del profesorado en Inteligencia Emocional (en adelante IE), como meta para mejorar el proceso educativo del alumnado, y por lo tanto, la necesidad de incluir una asignatura de educación emocional en el título de Grado de Educación Infantil (en adelante EI), y Educación Primaria (en adelante EP), que de a los futuros maestros la posibilidad de formarse en dicho ámbito. Para ello, se realiza un instrumento de recogida de datos compuesto por una entrevista semi-estructurada y el cuestionario TMMS-24 de Extremera y Fernández-Berrocal. Los resultados obtenidos muestran que el profesorado y futuro profesorado de EI y EP, poseen una elevada IE y consideran que ésta juega un papel importante en el desarrollo del alumnado. Sin embargo, la mayoría no ha recibido una buena formación en dicho ámbito y por lo tanto, carecen de los conocimientos y herramientas necesarias para transmitirla en el aula.Grado en Educación Infanti

The P. aeruginosa effector Tse5 forms membrane pores disrupting the membrane potential of intoxicated bacteria

The type VI secretion system (T6SS) of Pseudomonas aeruginosa injects effector proteins into neighbouring competitors and host cells, providing a fitness advantage that allows this opportunistic nosocomial pathogen to persist and prevail during the onset of infections. However, despite the high clinical relevance of P. aeruginosa, the identity and mode of action of most P. aeruginosa T6SS-dependent effectors remain to be discovered. Here, we report the molecular mechanism of Tse5-CT, the toxic auto-proteolytic product of the P. aeruginosa T6SS exported effector Tse5. Our results demonstrate that Tse5-CT is a pore-forming toxin that can transport ions across the membrane, causing membrane depolarisation and bacterial death. The membrane potential regulates a wide range of essential cellular functions; therefore, membrane depolarisation is an efficient strategy to compete with other microorganisms in polymicrobial environments.We gratefully acknowledge the Laboratories of Dr. Daniel Ladant (Institut Pasteur, Paris) and Dr. Victor de Lorenzo (Centro Nacional de Biotecnologia, Madrid) for the plasmids received (pKTop and pSEVA plasmids, respectively). Also, we would like to acknowledge the Laboratory of Dr. Joseph Mougous for the P. aeruginosa strains received. The technical assistance from Cristina Civantos and Adrian Ruiz is also very much appreciated. We acknowledge the FGCZ for the mass spectrometry analyses and the technical support (Functional Genomics Center Zurich (FGCZ), University/ETH Zurich). D.A.-J. acknowledges support by the MINECO Contracts CTQ2016-76941-R and PID2021-127816NB-I00, Fundacion Biofisica Bizkaia, the Basque Excellence Research Centre (BERC) programme, and IT709-13 and IT1745-22 of the Basque Government, and Fundacion BBVA. A.G.-M. acknowledges the financial support received from the Spanish Ministry of Universities and the Grants for the requalification of the Spanish university system for 2021-2023, financed by the European Union-Next Generation EU-Margarita Salas Modality. A.A. acknowledges support from the Spanish Ministry of Science and Innovation (Project 2019-108434GB-I00 funded by MCIN/AEI/10.13039/501100011033), Generalitat Valenciana (project AICO/2020/066) and Universitat Jaume I (project UJI-B2018-53). M.Q.-M. acknowledges support from the Spanish Ministry of Science and Innovation (Project IJC2018-035283-I funded by MCIN/AEI/10.13039/501100011033) and Universitat Jaume I (project UJI-A2020-21). P.B acknowledges the financial support received from the Spanish Ministry of Science and Innovation through the Ramon y Cajal Programme (contract RYC2019-026551-I)

Validation of the new graded prognostic assessment scale for brain metastases: a multicenter prospective study

<p>Abstract</p> <p>Background</p> <p>Prognostic indexes are useful to guide tailored treatment strategies for cancer patients with brain metastasis (BM). We evaluated the new Graded Prognostic Assessment (GPA) scale in a prospective validation study to compare it with two published prognostic indexes.</p> <p>Methods</p> <p>A total of 285 newly diagnosed BM (<it>n </it>= 85 with synchronous BM) patients, accrued prospectively between 2000 and 2009, were included in this analysis. Mean age was 62 ± 12.0 years. The median KPS and number of BM was 70 (range, 20-100) and 3 (range, 1-50), respectively. The majority of primary tumours were lung (53%), or breast (17%) cancers. Treatment was administered to 255 (89.5%) patients. Only a minority of patients could be classified prospectively in a favourable prognostic class: GPA 3.5-4: 3.9%; recursive partitioning analysis (RPA) 1, 8.4% and Basic Score for BM (BSBM) 3, 9.1%. Mean follow-up (FU) time was 5.2 ± 4.7 months.</p> <p>Results</p> <p>During the period of FU, 225 (78.9%) patients died. The 6 months- and 1 year-OS was 36.9% and 17.6%, respectively. On multivariate analysis, performance status (<it>P </it>< 0.001), BSBM (<it>P </it>< 0.001), Center (<it>P </it>= 0.007), RPA (<it>P </it>= 0.02) and GPA (<it>P </it>= 0.03) were statistically significant for OS. The survival prediction performances' of all indexes were identical. Noteworthy, the significant OS difference observed within 3 months of diagnosis between the BSBM, RPA and GPA classes/groups was not observed after this cut-off time point. Harrell's concordance indexes <it>C </it>were 0.58, 0.61 and 0.58 for the GPA, BSBM and RPA, respectively.</p> <p>Conclusions</p> <p>Our data suggest that the new GPA index is a valid prognostic index. In this prospective study, the prediction performance was as good as the BSBM or RPA systems. These published indexes may however have limited long term prognostication capability.</p

Effect of aeration on nitrogen removal-associated microbial community in an innovative vertical cork-based constructed wetland for winery wastewater treatment

The wine industry produces large quantities of wastewater that often contains high levels of organic matter and nutrients, like nitrogen and phosphorous. In particular, nitrogen pollution can be harmful, even at low levels, since infants are vulnerable to nitrates in drinking water, and excess nitrogen can harm the health of soils and waterways. Herein, an innovative compact, modular, and mobile treatment wetland (TW) using cork by product as the only granular media was used to treat the final effluents from the Codorniu winery (Sant Sadurní d'Anoia, Spain). The TW was operated during two 5-month periods with or without intermittent induced aeration (40 min cycles, 90 L/min air flow rate). Nitrate (N-NO3) and total nitrogen (TN) removal were higher (52.8% and 46.8%, respectively, p < 0.05) during TW operation under aerated-condition. Additionally, qPCR analysis of 16S rRNA, nirS and nosZ genes revealed that intermittent induced aeration facilitates N-NO3 reduction by the stimulation of denitrifying bacteria in the TW biofilm (11.4% increase in nirS copies number/g cork sample, p < 0.05) as well as increasing the number of heterotrophic bacteria adhered to cork (25.5% increase in 16S rRNA copies number/g cork sample, p < 0.05). Moreover, SEM images demonstrated the suitability of cork as a resistant filter media for TW after long-term system operation (1.5 years). In conclusion, our results suggest that aeration improved ni- trogen compounds removal compared to the non-aerated period, without affecting phosphorous elimination. Additionally, residual cork is presented here in a circular bioeconomy view, as a suitable filling media to treat winery wastewater that can provide additional carbon source to increase C/N rate stimulating denitrification, as well as a reliable organic substrate for biomass growth.To LIFE Programme, the EU's financial instrument supporting environmental, nature conservation, and climate action projects throughout the EU that supports LIFE ECORKWASTE 14 ENV/ES/460.Peer ReviewedPostprint (published version

Jardins per a la salut

Facultat de Farmàcia, Universitat de Barcelona. Ensenyament: Grau de Farmàcia. Assignatura: Botànica farmacèutica. Curs: 2014-2015. Coordinadors: Joan Simon, Cèsar Blanché i Maria Bosch.Els materials que aquí es presenten són el recull de les fitxes botàniques de 128 espècies presents en el Jardí Ferran Soldevila de l’Edifici Històric de la UB. Els treballs han estat realitzats manera individual per part dels estudiants dels grups M-3 i T-1 de l’assignatura Botànica Farmacèutica durant els mesos de febrer a maig del curs 2014-15 com a resultat final del Projecte d’Innovació Docent «Jardins per a la salut: aprenentatge servei a Botànica farmacèutica» (codi 2014PID-UB/054). Tots els treballs s’han dut a terme a través de la plataforma de GoogleDocs i han estat tutoritzats pels professors de l’assignatura. L’objectiu principal de l’activitat ha estat fomentar l’aprenentatge autònom i col·laboratiu en Botànica farmacèutica. També s’ha pretès motivar els estudiants a través del retorn de part del seu esforç a la societat a través d’una experiència d’Aprenentatge-Servei, deixant disponible finalment el treball dels estudiants per a poder ser consultable a través d’una Web pública amb la possibilitat de poder-ho fer in-situ en el propi jardí mitjançant codis QR amb un smartphone

Development, Optimization and Validation of a Sustainable and Quantifiable Methodology for the Determination of 2,4,6-Trichloroanisole, 2,3,4,6-Tetrachloroanisole, 2,4,6-Tribromoanisole, Pentachloroanisole, 2-Methylisoborneole and Geosmin in Air

Compounds 2,4,6-trichloroanisole (TCA), 2,3,4,6-tetrachloroanisole (TeCA), 2,4,6-tribromoanisole (TBA) and pentachloroanisole (PCA), 2-methylisoborneol (2MIB) and geosmin (GSM) have been reported as being responsible for cork and wine taint. A sustainable method based on thermal desorption-gas chromatography–mass spectrometry (TD-GC/MS) has been developed and optimized, taking into account desorption parameters and chromatographic and mass spectrometric conditions. The combination of parameters that jointly maximized the compound detection was as follows: desorption temperature at 300 °C, desorption time at 30 min, cryo-temperature at 20 °C and trap high temperature at 305 °C. The proposed methodology showed a good linearity (R ≤ 0.994) within the tested range (from 0.1 to 2 ng) for all target compounds. The precision expressed as repeatability and reproducibility was RSD &lt; 10% in both. The limits of quantification ranged from 0.05 to 0.1 ng. The developed methodology and the sampling rates (R-values) of all targeted compounds (from 0.013 to 0.071 m3 h−1) were applied to the air analysis of two wineries. The results showed that the developed methodology is a sustainable and useful tool for the determination of these compounds in air

La investigación-acción aplicada en la asignatura de Biología y Geología de 4º ESO y la enseñanza de la célula y el ADN

The use of learning experiments allow to take advantage of some educational benefits such as the motivation of students since it learning process is carried out in more playful environments than class. Also, the student can experience in first person the scientist work: formulate hypothesis, establish protocols, do the experiments, reach conclusions and communicate the results. Practical skills and teamwork are worked. The overall objective of this study was to go in-depth on the evolution of the study of experimental sciences and didactic models, to find and analyze information about action research and specifically on learning experiments in order to make a first evaluation of their advantages and disadvantages and designing an intervention proposal focused on 4º ESO Biology and Geology grade specifically in cell and DNA themes. This proposal consists of fourteen sessions that have not been applied in the classroom. The technique to be followed in the proposal is action-research based on a didactic experiment. In conclusion, the teaching of science has changed over time as well as the needs of society. In addition, teachers have a wide variety of techniques in order to achieve science literacy. One of these techniques is action research that can be applied in the classroom by transforming a laboratory practices into a learning experiment where the teacher acts as a guide. This technique allows students to experience the scientific method first-hand.El uso de experimentos didácticos permite aprovechar los beneficios educativos que implica esta técnica como el incremento de la motivación de los alumnos debido al hecho que el proceso de enseñanza se realiza en ambientes más lúdicos que el aula. Además, el alumno puede experimentar en primera persona el trabajo de un científico: desde formular hipótesis, elaborar protocolos, realizar los experimentos, obtener conclusiones y, comunicar los resultados. Igualmente, se trabajan habilidades prácticas y se potencia el trabajo en equipo. El objetivo general de este trabajo ha sido profundizar en la evolución del estudio de las ciencias experimentales y los modelos didácticos, buscar y analizar información sobre técnica de la investigación-acción y concretamente sobre les experimentos didácticos con el fin de hacer una primera evaluación de sus ventajas e inconvenientes y diseñar una propuesta de intervención enfocada a la enseñanza de Biología y Geología de 4º ESO sobre la célula y el ADN que consta de catorce sesiones que no se ha podido aplicar en el aula. La técnica que se va a seguir en la propuesta es la investigación-acción a partir de la realización de un experimento didáctico. Se concluye que la enseñanza de las ciencias ha ido cambiando a lo largo del tiempo al igual que las necesidades de la sociedad de manera que los docentes disponen de una amplia variedad de técnicas con el fin de alcanzar la alfabetización científica. Una de estas técnicas es la investigación-acción que se puede aplicar en el aula mediante la transformación de una actividad práctica en un experimento didáctico docente actúa como guía. Esta técnica permite a los alumnos experimentar en primera persona el método científico

Caracterització del suro i subproductes de la indústria surera. Valoració d'aquests com a biosorbents d'hidrocarburs aromàtics policíclics en aigües d'escorrentia

The main objective of this thesis is to characterize and evaluate the capacity of cork and by-products of the cork industry (collectively called as cork samples) as biosorbents of aqueous polycyclic aromatic hydrocarbons (PAHs). In order to achieve this goal, the following studies were performed. One of the considered applications for the reuse of treated water is for boiled cork planks given that, this not only would improve the water resources management but also would increase the added value of the by-products from the cork industry using it in the sector itself. According to this, an economical study of the process was performed. Finally, the possibility of regenerating the contaminated biosorbent using biodegration to remove previously PAH adsorbed, was evaluated. In this case, three ligninolytic fungi (with degradation capacity previously reported) and three non-ligninolytic fungi characteristic of cork itself was used to inoculate polluted cork with anthracene (chosen as a representative PAH). The identification of anthracene degradation products generated and the elucidation of degradation pathway in the fungus showing the highest anthracene removal were performed. This last step of the thesis is very important as it closes the cork cycle as biosorbent of PAHsL'objectiu general d'aquesta tesi ha estat caracteritzar i avaluar la capacitat del suro i subproductes (en conjunt anomenats mostres de suro) de la indústria surera com a biosorbents d'hidrocarburs aromàtics policíclics (HAPs) presents en l'aigua d'escorrentia. Per tal d’assolir aquest objectiu s’han dut a terme una sèrie d’estudis que es detallen a continuació. Un dels usos que s’ha contemplat per a la reutilització de l’aigua d’escorrentia tractada és la seva aplicació en la bullida de les planxes de suro donat que això, no només implicaria millores en la gestió dels recursos hídrics, sinó que també donaria valor afegit a un subproducte del sector surer aplicant-lo en el propi sector. També s'ha avaluat la possibilitat de regenerar el biosorbent contaminat eliminant els HAPs que ha adsorbit anteriorment, a partir de la biodegradació. En aquest cas, el suro contaminat amb antracè o HAP escollit com a compost representatiu, s'ha inoculat amb tres fongs ligninolítics (amb activitat degradadora contrastada) i tres fongs no ligninolítics característics del suro. Després, s'han identificat els productes intermedis generats durant la descontaminació, i s'ha proposat el mecanisme de degradació de l'antracè pel fong que ha presentat major capacitat de degradació. Aquesta darrera etapa és molt important ja que tanca el cicle de l'ús del suro com a biosorbent d'HAP

Study of the variability in chemical composition of bark layers of Quercus Suber L. from different production areas

Cork is the bark of the cork oak tree (Quercus suber L), a renewable and biodegradable raw bioresource concentrated mainly in the Mediterranean region. Development of its potential uses as a biosorbent will require the investigation of its chemical composition; such information can be of help to understand its interactions with organic pollutants. The present study investigates the summative chemical composition of three bark layers (back, cork, and belly) of five Spanish cork samples and one cork sample from Portugal. Suberin was the main component in all the samples (21.1 to 53.1%), followed by lignin (14.8 to 31%), holocellulose (2.3 to 33.6%), extractives (7.3 to 20.4%), and ash (0.4 to 3.3%). The Kruskal-Wallis test was used to determine whether the variations in chemical composition with respect to the production area and bark layers were significant. The results indicate that, with respect to the bark layer, significant differences were found only for suberin and holocellulose contents: they were higher in the belly and cork than in the back. Based on the results presented, cork is a material with a lot of potential because of its heterogeneity in chemical compositio