La estimación de un indicador de brecha del producto a partir de encuestas y datos reales

Una estimación adecuada de la brecha del producto es un requisito indispensable para la conducción de la política monetaria bajo el régimen de inflación objetivo. Por esta razón, en la literatura y al interior del Banco de la República, se trabaja con una gran variedad de mediciones a partir de técnicas alternativas. Desafortunadamente, como la brecha del producto es una variable no observable, siempre hay gran incertidumbre sobre cualquier estimación. Para sobreponerse a este problema, en el Departamento de Inflación se siguen regularmente una amplia gama de indicadores, en especial encuestas de opinión empresarial y datos de actividad, para mejorar la comprensión de la situación de la economía en el ciclo y para identificar posibles presiones de demanda. Aunque en principio parece razonable y adecuado contar con gran cantidad de medidas y monitorear diversas fuentes de información complementarias, en la práctica resulta problemático poder resumir de manera eficiente la información disponible en una sola medida que pueda ser utilizada para producir pronósticos de inflación y recomendaciones de política. Hasta hace poco, la reducción de la información se hacía a partir del juicio de los expertos sobre los pesos relativos que se asignaban para cada medición y para la información proveniente de encuestas. Lo cual potencialmente podía conducir a un problema de variables omitidas y a sesgar cualquier estimación. Para resolver este problema en este trabajo se estima un indicador de brecha del producto como el factor no observado entre los datos disponibles. Dicho factor se estima utilizando componentes principales estáticos, el cual debe resumir la información contenida en los datos mientras que excluye cualquier error presente en las medidas originales. La calidad del indicador se evalúa posteriormente a partir de su capacidad predictiva de la inflación básica de bienes no transables en Colombia, mediante una Curva de Phillips híbrida. Los resultados sugieren, como se esperaba, que el indicador de brecha del producto es superior a cualquiera de las medidas individuales para señalar presiones de demanda, puesto que combina de manera eficiente la información de varias fuentes. Adicionalmente se encuentra, que los pronósticos fuera de muestra se pueden mejorar si se excluyen para la estimación del indicador aquellas medidas que provienen de filtros estadísticos. Lo cual reafirma la importancia de seguir fuentes alternativas de información, en especial de encuestas de opinión industrial, a pesar de que la industria tan sólo pesa un 15% del PIB en Colombia.Brecha del producto, componentes principales, Curva de Phillips, Colombia.

Casimir torque

We develop a formalism for the calculation of the flow of angular momentum carried by the fluctuating electromagnetic field within a cavity bounded by two flat anisotropic materials. By generalizing a procedure employed recently for the calculation of the Casimir force between arbitrary materials, we obtain an expression for the torque between anisotropic plates in terms of their reflection amplitude matrices. We evaluate the torque in 1D for ideal and realistic model materials.Comment: 8 pages, 4 figs, Submitted to Proc. of QFEXT'05, to appear in J. Phys.

High-fiber diets for fattening pigs

Objective:  To establish the feasibility and benefits offered by implementing pig diets with high fiber content. Design/methodology: A bibliographic review of the concept of the practical application of diets for pigs with the inclusion of fibrous ingredients. Results: Formulating high-fiber pig diets maintains or improves productive performance and offers additional gut health benefits. Study limitations/implications: The lack of knowledge of the net energy and digestible amino acid values of the fibrous ingredients limits the adequate formulation of diets for pigs. Findings/conclusions: The inclusion of high fiber ingredients in the diet for pigs can partially substitute traditional ingredients reducing costs and obtaining health benefits.Objective: To establish the feasibility and benefits of implementing high-fiber diets for pigs. Design/Methodology: A literature review of the practical application of pig diets with the inclusion of fibrous ingredients was carried out. Results: The formulation of high-fiber diets for pigs maintains or improves productive performance and provides additional gut health benefits. Study Limitations/Implications: Lack of information about the net energy and amino acid digestibility values of fibrous ingredients limits the proper formulation of pig diets. Findings/Conclusions: The inclusion of high-fiber ingredients in pig diets can partially replace traditional ingredients, consequently reducing costs and providing health benefits

Efficacy of naproxen with or without esomeprazole for pain and inflammation in patients after bilateral third molar extractions : a double blinded crossover study

Using a double-blinded randomized crossover design, this study aimed to evaluate acute postoperative pain management, swelling and trismus in 46 volunteers undergoing extractions of the two lower third molars, in similar positions, at two different appointments who consumed a tablet of either NE (naproxen 500 mg + esomepraz ole 20 mg) or only naproxen (500 mg) every 12 hours for 4 days. Parameters were analyzed: self-reported pain intensity using a visual analog scale (VAS) pre- and postoperative mouth opening; incidence, type and severity of adverse reactions; total quantity consumed of rescue medication; and pre- and postoperative swelling. Female volunteers reported significantly more postoperative pain at 1, 1.5, 2, 3 and 4hrs after surgery while also taking their first rescue medication at a time significantly earlier when consuming NE when compared to naproxen (3.7hrs and 6.7hrs). Conversely, no differences were found between each drug group in males. In conclusion, throughout the entire study, pain was mild after using either drug in both men and women with pain scores on average well below 40mm (VAS), although in women naproxen improved acute postoperative pain management when compared to NE

Prevalencia de Trypanosoma vivax en bovinos de Villavicencio por pruebas parasitológicas directas y por inmunofluorescencia indirecta.

Para determinar la prevalencia de tripanosomiasis bovina en Villavicencio, Colombia, empleando la técnica indirecta de anticuerpos fluorescentes, a manera de comparación se utilizaron los métodos parasitológicos directos. Se examinaron 500 bovinos mayores de un año en 50 fincas escogidas al azar. Se encontraron 47 reactores positivos o una prevalencia real entre 6.8 y 9.4 por ciento, utilizando la prueba de inmunofluorescencia indirecta. No se encontraron animales positivos al emplear los métodos parasitológicos directos (preparación en fresco, frotis delgado, gota gruesa, centrifugación en tubo capilar o técnica de Woo). Lo anterior indica la ausencia de correlación entre los procedimientos utilizados. Se comprueba que los métodos parasitológicos directos son solo de ayuda en los casos que cursan con parasitemias detectables. Se puede afirmar que el Tripanosoma vivax es endémico en esta región tropical de Colombia, destacándose la importancia de la tripanosomiasis como enfermedad inmunodepresora y los posibles efectos que puede tener sobre los programas de vacunación que se realicen en los bovinos de esta zona. Los reactores positivos pueden ser reservorios potenciales de tripanosomas, los cuales podrían transmitirse dada la presencia de algunos insectos vectoresGanado de leche-Ganadería lech

A consolidated analysis of the physiologic and molecular responses induced under acid stress in the legume-symbiont model-soil bacterium <i>Sinorhizobium meliloti</i>

Abiotic stresses in general and extracellular acidity in particular disturb and limit nitrogen-fixing symbioses between rhizobia and their host legumes. Except for valuable molecular-biological studies on different rhizobia, no consolidated models have been formulated to describe the central physiologic changes that occur in acid-stressed bacteria. We present here an integrated analysis entailing the main cultural, metabolic, and molecular responses of the model bacterium Sinorhizobium meliloti growing under controlled acid stress in a chemostat. A stepwise extracellular acidification of the culture medium had indicated that S. meliloti stopped growing at ca. pH 6.0-6.1. Under such stress the rhizobia increased the O2 consumption per cell by more than 5-fold. This phenotype, together with an increase in the transcripts for several membrane cytochromes, entails a higher aerobic-respiration rate in the acid-stressed rhizobia. Multivariate analysis of global metabolome data served to unequivocally correlate specific-metabolite profiles with the extracellular pH, showing that at low pH the pentose-phosphate pathway exhibited increases in several transcripts, enzymes, and metabolites. Further analyses should be focused on the time course of the observed changes, its associated intracellular signaling, and on the comparison with the changes that operate during the sub lethal acid-adaptive response (ATR) in rhizobia.Facultad de Ciencias ExactasCentro de Investigación y Desarrollo en Fermentaciones IndustrialesInstituto de Biotecnologia y Biologia Molecula

Cell cycle control and HIV-1 susceptibility are linked by CDK6-Dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells

Proliferating cells are preferentially susceptible to infection by retroviruses. Sterile α motif and HD domain-containing protein-1 (SAMHD1) is a recently described deoxynucleotide phosphohydrolase controlling the size of the intracellular deoxynucleotide triphosphate (dNTP) pool, a limiting factor for retroviral reverse transcription in noncycling cells. Proliferating (Ki67+) primary CD4+ T cells or macrophages express a phosphorylated form of SAMHD1 that corresponds with susceptibility to infection in cell culture. We identified cyclin-dependent kinase (CDK) 6 as an upstream regulator of CDK2 controlling SAMHD1 phosphorylation in primary T cells and macrophages susceptible to infection by HIV-1. In turn, CDK2 was strongly linked to cell cycle progression and coordinated SAMHD1 phosphorylation and inactivation. CDK inhibitors specifically blocked HIV-1 infection at the reverse transcription step in a SAMHD1-dependent manner, reducing the intracellular dNTP pool. Our findings identify a direct relationship between control of the cell cycle by CDK6 and SAMHD1 activity, which is important for replication of lentiviruses, as well as other viruses whose replication may be regulated by intracellular dNTP availability. © 2014 by The American Association of Immunologists, Inc

Sequential versus nonsequential two-photon double ionization of the D2 molecule at 38 eV

ABSTRACT: A simple theoretical model is used to interpret recent experimental results for two-photon double ionization (DI) of D2 at 38 eV. We show that the measured kinetic energy distribution associated with emission of two protons can be interpreted as a sum of two processes: a sequential and an instantaneous absorption of the two incident photons. These processes lead to peaks in di erent regions of the spaectrum

European ADPKD Forum multidisciplinary position statement on autosomal dominant polycystic kidney disease care

Autosomal dominant polycystic kidney disease (ADPKD) is a chronic, progressive condition characterised by the development and growth of cysts in the kidneys and other organs and by additional systemic manifestations. Individuals with ADPKD should have access to life-long, multidisciplinary, specialist and patient-centred care involving: 1) A holistic and comprehensive assessment of the manifestations, complications, prognosis and impact of the disease (in physical, psychological and social terms) on the patient and their family; 2) Access to treatment to relieve symptoms, manage complications, preserve kidney function, lower the risk of cardiovascular disease, and maintain quality of life; 3) Information and support to help patients and their families act as fully informed and active partners in care, i.e. to maintain self-management approaches, deal with the impact of the condition, and participate in decision-making regarding healthcare policies, services and research. Building on discussions at an international Roundtable of specialists and patient advocates involved in ADPKD care, this paper sets out 1) The principles for a patient-centred, holistic approach to the organisation and delivery of ADPKD care in practice, with a focus on multi-specialist collaboration and shared-decision making, 2) The rationale and knowledge base for a Route Map for ADPKD care intended to help patients navigate the services available to them and to help stakeholders and decision-makers take practical steps to ensure that all patients with ADPKD can access the comprehensive multi-specialist care to which they are entitled. Further multispecialty collaboration is encouraged to design and implement these services, and to work with patient organisations to promote awareness building, education, and research

What pulmonologists think about the asthma–COPD overlap syndrome

Background: Some patients with COPD may share characteristics of asthma; this is the so-called asthma–COPD overlap syndrome (ACOS). There are no universally accepted criteria for ACOS, and most treatments for asthma and COPD have not been adequately tested in this population. Materials and methods: We performed a survey among pulmonology specialists in asthma and COPD aimed at collecting their opinions about ACOS and their attitudes in regard to some case scenarios of ACOS patients. The participants answered a structured questionnaire and attended a face-to-face meeting with the Metaplan methodology to discuss different aspects of ACOS. Results: A total of 26 pulmonologists with a mean age of 49.7 years participated in the survey (13 specialists in asthma and 13 in COPD). Among these, 84.6% recognized the existence of ACOS and stated that a mean of 12.6% of their patients might have this syndrome. In addition, 80.8% agreed that the diagnostic criteria for ACOS are not yet well defined. The most frequently mentioned characteristics of ACOS were a history of asthma (88.5%), significant smoking exposure (73.1%), and postbronchodilator forced expiratory volume in 1 second/forced vital capacity ,0.7 (69.2%). The most accepted diagnostic criteria were eosinophilia in sputum (80.8%), a very positive bronchodilator test (69.2%), and a history of asthma before 40 years of age (65.4%). Up to 96.2% agreed that first-line treatment for ACOS was the combination of a long-acting β2-agonist and inhaled steroid, with a long-acting antimuscarinic agent (triple therapy) for severe ACOS. Conclusion: Most Spanish specialists in asthma and COPD agree that ACOS exists, but the diagnostic criteria are not yet well defined. A previous history of asthma, smoking, and not fully reversible airflow limitation are considered the main characteristics of ACOS, with the most accepted first-line treatment being long-acting β2-agonist/inhaled corticosteroids