Students’ experiences of university social responsibility and perceptions of satisfaction and quality of service

The principal aim of this paper is to identify the factors that define students’ perceptions of university social responsibility (USR) in a Spanish university, and analyse the impact of that view on their perceptions of satisfaction and quality of service. Particularly, it is hypothesized that the overall perception of university social responsibility has a positive effect on students’ experiences of satisfaction, partially mediated by the assessment regarding the quality of university services. In doing that, a self-report study was conducted with a total sample of 400 undergraduate students of the University of León, in Spain. Structural equation modeling with PLS was used to test the students’ overall perception of USR in order to achieve higher standards of quality of service and satisfaction. Results supported a structure of six factors explaining students’ views regarding university social responsibility, of which only internal management affects the overall perception. Likewise, quality of service and satisfaction are strongly correlated among them. Implications of these findings for marketing in university settings are discussed.Keywords: University social responsibility, public marketing, higher education, satisfaction, quality of service, Spain</p

DNA expansions generated by human Polμ on iterative sequences

Polm is the only DNA polymerase equipped with template-directed and terminal transferase activities. Polm is also able to accept distortions in both primer and template strands, resulting in misinsertions and extension of realigned mismatched primer terminus. In this study, we propose a model for human Polm-mediated dinucleotide expansion as a function of the sequence context. In this model, Polm requires an initial dislocation, that must be subsequently stabilized, to generate large sequence expansions at different 50-P-containing DNA substrates, including those that mimic non-homologous endjoining (NHEJ) intermediates. Our mechanistic studies point at human Polm residues His329 and Arg387 as responsible for regulating nucleotide expansions occurring during DNA repair transactions, either promoting or blocking, respectively, iterative polymerization. This is reminiscent of the role of both residues in the mechanism of terminal transferase activity. The iterative synthesis performed by Polm at various contexts may lead to frameshift mutations producing DNA damage and instability, which may end in different human disorders, including cancer or congenital abnormalitiesMinisterio de Ciencia y Tecnologia [BFU2009-10085 and CONSOLIDER CSD2007-00015]; Fundacion Ramon Areces (to Centro de Biologia Molecular ‘‘Severo Ochoa’’); Ministerio de Educacion y Ciencia (to A.A.); Comunidad Autonoma de Madrid (to M.J.M.). Funding for open access charge: Comunidad de Madrid grant [S2011/BMD-2361

Regional differences in AIDS and non-AIDS related mortality in HIV-positive individuals across Europe and Argentina: the EuroSIDA study

BACKGROUND Differences in access to care and treatment have been reported in Eastern Europe, a region with one of the fastest growing HIV epidemics, compared to the rest of Europe. This analysis aimed to establish whether there are regional differences in the mortality rate of HIV-positive individuals across Europe, and Argentina. METHODS 13,310 individuals under follow-up were included in the analysis. Poisson regression investigated factors associated with the risk of death. FINDINGS During 82,212 person years of follow-up (PYFU) 1,147 individuals died (mortality rate 14.0 per 1,000 PYFU (95% confidence interval [CI] 13.1-14.8). Significant differences between regions were seen in the rate of all-cause, AIDS and non-AIDS related mortality (global p<0.0001 for all three endpoints). Compared to South Europe, after adjusting for baseline demographics, laboratory measurements and treatment, a higher rate of AIDS related mortality was observed in East Europe (IRR 2.90, 95%CI 1.97-4.28, p<.0001), and a higher rate of non-AIDS related mortality in North Europe (IRR 1.51, 95%CI 1.24-1.82, p<.0001). The differences observed in North Europe decreased over calendar-time, in 2009-2011, the higher rate of non-AIDS related mortality was no longer significantly different to South Europe (IRR 1.07, 95%CI 0.66-1.75, p = 0.77). However, in 2009-2011, there remained a higher rate of AIDS-related mortality (IRR 2.41, 95%CI 1.11-5.25, p = 0.02) in East Europe compared to South Europe in adjusted analysis. INTERPRETATIONS There are significant differences in the rate of all-cause mortality among HIV-positive individuals across different regions of Europe and Argentina. Individuals in Eastern Europe had an increased risk of mortality from AIDS related causes and individuals in North Europe had the highest rate of non-AIDS related mortality. These findings are important for understanding and reviewing HIV treatment strategies and policies across the European region

La primera cura : comedia en tres actos y en verso

Copia digital. Valladolid : Junta de Castilla y León. Consejería de Cultura y Turismo, 2009-201

Comparative analysis of the mechanical limits of resistance in implant/abutment set of a new implant design: An in vitro study

Objective: The aim of the present in vitro study was to evaluate the resistance on quasi-static forces and in the fatigue mechanical cycling of a new implant design compared to two other conventional implant designs. Materials and methods: Eighty-eight implants with their respective abutments were tested and distributed into four groups (n = 22 per group): Morse taper connection implant (MT group), conventional external hexagon implant (EH con group), new Collo implant of external hexagon with the smooth portion out of the bone insertion (EH out group), and new Collo implant of external hexagon with the implant platform inserted to the bone level (EH bl group). All the sets were subjected to quasi-static loading in a universal testing machine, and we measured the maximum resistance force supported by each sample. Another 12 samples from each group were submitted to the cyclic fatigue test at 4 intensities of forces (n = 3 per force): 80%, 60%, 40%, and 20%. The number of cycles supported by each sample at each force intensity was evaluated. Results: The three groups of implants with external hexagon connection had similar maximum strength values of the sets (p > 0.05). Meanwhile, samples from the MT group showed the highest resistance values in comparison to the other three groups (p < 0.05). In the fatigue test, the Collo out group supported a smaller number of cycles that led to the fracture than the other 3 groups proposed at loads of 80%, 60%, and 40%, and only at the load value of 20% all groups had the same performance. Conclusions: Within the limitations of the present in vitro study, the results showed that the new Collo implant performs better when installed at bone level.Part of this work was supported by Ministry of Science and Innovation—Grant PID2020-116693RB-C21 funded by MCIN/AEI/ 10.13039/501100011033. The author Sergio Alexandre Gehrke was funded by post-doctoral grant n˚ 2021/PER/00020 from the Ministerio de Universidades under the program "Ayudas para la recualificacio´n del sistema universitario español de la Universidad Miguel Hernandez" modalida

The management of the sport from an educational perspective in Human Kinetics

La investigación que se presenta trata de vincular la Administración Local con la planificación, la gestión del deporte y el funcionamiento de las políticas públicas. Tiene como objetivo conocer las percepciones de los miembros de la comunidad sobre la gestión de los servicios ofrecidos desde la Administración Local (especialmente los deportivos), y aportar alternativas de cambio para la mejora de gestión municipal en clave educativa de Motricidad Humana. Presentado como un estudio de casos, se trata de un análisis descriptivo-interpretativo que emplea una metodología cualitativa, donde la entrevista en profundidad se presenta como la principal herramienta para la obtención de datos. Los resultados se sintetizan en que los agentes hablan más de la forma de entender el entorno, municipio, deporte, asociaciones (la crítica) que propiamente de propuestas de mejora y cambio. Como principales conclusiones, diremos que el deporte local debe huir de las modas y centrarse más en la motricidad propia de los pueblos y desarrollar un deporte-alternativa, en lugar de un deporte repetición.The research presented attempts to link local government planning, sports management and operation of public policy. It aims to investigate the perceptions of community members on the management of the services offered by the Local Administration (especially the ones relative to sport), and to contribute to alternatives for change, in order to improve municipal management in Human Kinetics using an educational perspective. Presented as a case study, this work is a descriptive and interpretive analysis which uses a qualitative methodology, where in depth interview is presented as the main tool for collecting data. Results show that agents talk more about understanding the environment, city/town, sport, and associations (criticism) than about actual proposals for improvement and change. It is concluded that local sport must steer clear of trends such as sport repetition and focus more on peoples’ own motor functions and on developing a sport alternative. Keywords. Public policies, human kinetics, management, qualitative methodology, local administration.S

A New Biphasic Dicalcium Silicate Bone Cement Implant

This is the peer reviewed versión of the following article: "A New Biphasic Dicalcium Silicate Bone Cement Implant ", which has been published in final form at [doi:10.3390/ma10070758],. This article May be used for non-comercial pipotes in accordance with Wiley Terms an Conditions for Use of Self-Archived Versions.Odontologí