Prevalence of HBV and HCV infections and associated risk factors in addict prisoners

High prevalence of HBV and HCV infections in prisoners suggests them as one of the main infection source in community. Preventive measures can possibly decrease their rate of infection and infectivity. We evaluated prevalence of HBV and HCV infections and their relation to dangerous behavior in addict prisoners. This was a cross-sectional study included prisoners of central provinces of Iran who were evaluated for HBV and HCV in 2003. All of 1431 prisoners filled out questionnaires that were evaluated for HBsAg and HCV antibody. There were 51 prisoners (3.5) who were HBsAg positive and 513 prisoners (35.8) had HCV antibody. Odd's ratio for HBV and HCV were 10.3 and 9.6 for IVDA, respectively. This study showed that the HBV and specially HCV infection had high prevalence among prisoners. In comparison to rate of HBsAg and HCV infection in general population of Iran, this study showed that the HBsAg was 2 times and HCV infection was 70 times more frequent in prisoner than in general population of Iran. The education for dangerous behavior is strongly recommended to control this persistent infection source for hepatitis B and C in the community

Investigating Cause and Effect Relationships and Prioritizing of GM Assessment Indexes based on Economic, Resources, Energy and Environmental Attributes and PSR Framework using Gray DEMATAL

Nowadays the role of green manufacturing (GM) in sustainable development is evident and irrefutable therefore organizations seek to introduce themselves green in order to maintain their image toward their community. The usual method of sustainability and greenness assessment of a system is making use of indicators and indexes which are classified into several groups based on their characteristics. An important type of index categorization is based on four sustainability attributes including economic, energy, environment and recourses as well as pressure-state-response model (PSR). Because of the research gap about interactions relationships on indexes and investigating their influence others and influence by others. Since, indexes in each group could be effective on other indexes and be overlapped to some extent, it is necessary to prioritize and evaluate cause and effect relations by use of an appropriate method. We consider the relationship and prioritize most important indexes to evaluate manufacturing' greenness based on aforementioned sustainability attributes and PSR model. Purpose data is gathered by survey GM experts questionnaires, including 41 indexes plus 4 mentioned attributes, totally as 45 factors in 13 groups. In order to data analysis, with respect to the non-certainty and insufficient information, Grey DEMATEL method is used.Atualmente, o papel da manufatura verde (GM, Green Manufacturing) no desenvolvimento sustentável é evidente e irrefutável, portanto, as organizações procuram se apresentar “verdes” para manter sua imagem em sua comunidade. O método usual de avaliação da sustentabilidade e do verdor de um sistema é o uso de indicadores e índices que são classificados em vários grupos com base em suas características. Um tipo importante de categorização de índices é baseado em quatro atributos de sustentabilidade, incluindo econômico, energia, meio ambiente e recursos, além do modelo pressão-resposta-estado (PSR, Pressure-State-Response). Tendo em vista a lacuna de pesquisa sobre as relações de interações em índices faz-se necessário investigar a influência de outros e quais são influenciados por outros. Como os índices em cada grupo podem ser efetivos em outros índices e serem sobrepostos em certa medida, assim é essencial priorizar e avaliar as relações de causa e efeito pelo uso de um método apropriado. Consideramos o relacionamento e priorizamos os índices mais importantes para avaliar o verdor da manufatura com base nos atributos de sustentabilidade e no modelo de PSR. Os dados são coletados por questionários especializados em GM, incluindo 41 índices mais os 4 atributos mencionados, totalizando 45 fatores em 13 grupos. A fim de analisar os dados, no que diz respeito às informações não seguras e insuficientes, é utilizado o método Gray DEMATEL

Faculty Members and Students’ Opinion about Quality of Services Provided by the Central Library of Kerman University of Medical Sciences

Background & Objective : Libraries are among main parts of universities as libraries of high quality lead to improvement in education and research within universities and the society. Assessing quality of services in educational systems is important to improve quality of provided services. This study was conducted to assess the quality of services provided by the central library of Kerman University of Medical Sciences from the faculty members and students’ point of view . Methods : In this study, 200 faculty members and students of Kerman University of Medical Sciences were chosen using stratified random sampling. The data was collected using LibQUAL+TM standard questionnaire after its validity and reliability were confirmed Results : Our findings showed that the mean score of general satisfaction of the central library’s provided services was 6.13 out of 9. Among the three aspects of library service quality, information control was the most satisfactory factor (5.98) which was followed by efficacy of services (5.96) and the library’s atmosphere (5.89). Faculty members were more satisfied with the central library’s provided services in all aspects compared to students, although this difference was not significant. The most frequent referral to the central library and using references was once a month. Conclusion : Although the findings of this study were suggestive of faculty members and students’ relative satisfaction of provided services, improving quality of services necessitates better and more organized planning. Improvement of library service quality can lead to promoting faculty members and students’ scientific level in universities of medical sciences, medical knowledge, and medical education . Keywords: Service Quality, LibQUAL+TM survey, Faculty member, Student

The effect of topical olive oil on prevention of bedsore in intensive care units patients

Background: Bedsores are injuries to skin and underlying tissues caused by prolonged pressure. Although, some methods like frequently changing position and using particular tools are used for preventing and caring of pressure ulcers, their prevention would still be as a vital urgency. Olive oil is an herbal product with potential preventive effects to prevent bedsores because of its numerous medical properties. The major aim of this study was to determine whether topical olive oil can prevent the risk of developing bedsores in I.C.U. patients.  Methods: This clinical trial was accomplished in 2014 with 60 patients who were selected by simple random sampling method into intervention and control groups. During three weeks, the control group had received routine skin care, while the intervention group had received topical Olive oil in addition to the routine care. Statistical analysis, including Chi-square, T-test and Fisher’s tests, were performed with SPSS version 20 software.  Results: The intervention group had contained 19 male and 11 female, with an average age of 60.46 ± 18.06 and the control group had contained 20 male, 10 female, with an average age of 50.96 ± 21.38. Five patients (16%) who received routine care plus topical olive oil had developed bedsore after an average of 18.73 ± 5.36 days and twelve patients (40%) who received routine care only had developed bedsore after an average of 15.46 ± 7.40 days. The risks of developing bedsores between two groups were statistically significant (P=0.03).  Conclusions: Our study has revealed potential effects of topical olive oil to prevent bedsores in I.C.U. patients.

Prevalence of Transfusion Transmitted Virus Infection in Hemodialysis Patients and Injection Drug Users Compared to Healthy Blood Donors in Isfahan, Iran

Introduction. The pathogenicity and transmission routes of Transfusion Transmitted Virus (TTV) remain unclear. The aim of this study was to determine the prevalence of TTV in hemodialysis patients, injecting drug users (IDUs), and healthy blood donors, in Isfahan, Iran. Method. In a case-control study, a total of 108 subjects were put into three groups namely Group I, 36 hemodialysis patients; Group II, 36 IDUs; and Group III, 36 healthy blood donors as the control group. A 5 ml blood sample was collected from each subject in an EDTA-containing tube. Samples were tested for TTV DNA by means of real-time polymerase chain reaction (PCR). Results. The mean age was years. Seventy-one subjects (66%) were male. Of the108 cases, 30 (27.8%) were TTV positive and 78 (72.2%) were TTV negative. The prevalence of TTV in IDUs [21 (58%)] was significantly higher than in the other groups [group I: 6 (17 %) and group III: 3 (8%)] (). Conclusion. The prevalence of TTV in IDUs is significantly higher than in both hemodialysis patients and general population in Isfahan, Iran. It seems necessary to take serious measures to reduce the risk of TTV transmission to IDUs’ close contacts and health care providers

The global burden of adolescent and young adult cancer in 2019 : a systematic analysis for the Global Burden of Disease Study 2019

Background In estimating the global burden of cancer, adolescents and young adults with cancer are often overlooked, despite being a distinct subgroup with unique epidemiology, clinical care needs, and societal impact. Comprehensive estimates of the global cancer burden in adolescents and young adults (aged 15-39 years) are lacking. To address this gap, we analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019, with a focus on the outcome of disability-adjusted life-years (DALYs), to inform global cancer control measures in adolescents and young adults. Methods Using the GBD 2019 methodology, international mortality data were collected from vital registration systems, verbal autopsies, and population-based cancer registry inputs modelled with mortality-to-incidence ratios (MIRs). Incidence was computed with mortality estimates and corresponding MIRs. Prevalence estimates were calculated using modelled survival and multiplied by disability weights to obtain years lived with disability (YLDs). Years of life lost (YLLs) were calculated as age-specific cancer deaths multiplied by the standard life expectancy at the age of death. The main outcome was DALYs (the sum of YLLs and YLDs). Estimates were presented globally and by Socio-demographic Index (SDI) quintiles (countries ranked and divided into five equal SDI groups), and all estimates were presented with corresponding 95% uncertainty intervals (UIs). For this analysis, we used the age range of 15-39 years to define adolescents and young adults. Findings There were 1.19 million (95% UI 1.11-1.28) incident cancer cases and 396 000 (370 000-425 000) deaths due to cancer among people aged 15-39 years worldwide in 2019. The highest age-standardised incidence rates occurred in high SDI (59.6 [54.5-65.7] per 100 000 person-years) and high-middle SDI countries (53.2 [48.8-57.9] per 100 000 person-years), while the highest age-standardised mortality rates were in low-middle SDI (14.2 [12.9-15.6] per 100 000 person-years) and middle SDI (13.6 [12.6-14.8] per 100 000 person-years) countries. In 2019, adolescent and young adult cancers contributed 23.5 million (21.9-25.2) DALYs to the global burden of disease, of which 2.7% (1.9-3.6) came from YLDs and 97.3% (96.4-98.1) from YLLs. Cancer was the fourth leading cause of death and tenth leading cause of DALYs in adolescents and young adults globally. Interpretation Adolescent and young adult cancers contributed substantially to the overall adolescent and young adult disease burden globally in 2019. These results provide new insights into the distribution and magnitude of the adolescent and young adult cancer burden around the world. With notable differences observed across SDI settings, these estimates can inform global and country-level cancer control efforts. Copyright (C) 2021 The Author(s). Published by Elsevier Ltd.Peer reviewe

Global, regional, and national burden of disorders affecting the nervous system, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021

BackgroundDisorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by the International Classification of Diseases (ICD)-11, or a subset of cases of congenital, neonatal, and infectious conditions that cause neurological damage. Here, we estimate nervous system health loss caused by 37 unique conditions and their associated risk factors globally, regionally, and nationally from 1990 to 2021.MethodsWe estimated mortality, prevalence, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life-years (DALYs), with corresponding 95% uncertainty intervals (UIs), by age and sex in 204 countries and territories, from 1990 to 2021. We included morbidity and deaths due to neurological conditions, for which health loss is directly due to damage to the CNS or peripheral nervous system. We also isolated neurological health loss from conditions for which nervous system morbidity is a consequence, but not the primary feature, including a subset of congenital conditions (ie, chromosomal anomalies and congenital birth defects), neonatal conditions (ie, jaundice, preterm birth, and sepsis), infectious diseases (ie, COVID-19, cystic echinococcosis, malaria, syphilis, and Zika virus disease), and diabetic neuropathy. By conducting a sequela-level analysis of the health outcomes for these conditions, only cases where nervous system damage occurred were included, and YLDs were recalculated to isolate the non-fatal burden directly attributable to nervous system health loss. A comorbidity correction was used to calculate total prevalence of all conditions that affect the nervous system combined.FindingsGlobally, the 37 conditions affecting the nervous system were collectively ranked as the leading group cause of DALYs in 2021 (443 million, 95% UI 378–521), affecting 3·40 billion (3·20–3·62) individuals (43·1%, 40·5–45·9 of the global population); global DALY counts attributed to these conditions increased by 18·2% (8·7–26·7) between 1990 and 2021. Age-standardised rates of deaths per 100 000 people attributed to these conditions decreased from 1990 to 2021 by 33·6% (27·6–38·8), and age-standardised rates of DALYs attributed to these conditions decreased by 27·0% (21·5–32·4). Age-standardised prevalence was almost stable, with a change of 1·5% (0·7–2·4). The ten conditions with the highest age-standardised DALYs in 2021 were stroke, neonatal encephalopathy, migraine, Alzheimer's disease and other dementias, diabetic neuropathy, meningitis, epilepsy, neurological complications due to preterm birth, autism spectrum disorder, and nervous system cancer.InterpretationAs the leading cause of overall disease burden in the world, with increasing global DALY counts, effective prevention, treatment, and rehabilitation strategies for disorders affecting the nervous system are needed