1,344 research outputs found

    Global mapping of iron and titanium oxides in the lunar megaregolith and subsurface

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    [Abstract]: This paper reports mapping results obtained by remote sensing analysis of Iron and Titanium oxides in the megaregolith under the lunar Highlands regolith and in the subsurface under the Mare and South Pole Aitken basin regolith. FeO and TiO2 images were mosaicked from data extracted from the 1994 Clementine lunar orbiter mission from 600 N to 600 S, using the Lucey et al. technique (2000). These images then used to study the ejecta blanket for each of 2059 craters analysed using ISIS software (US Geological Survey). Average weight percentage values for each crater ejecta blanket were interpolated to derive underlying global Province Maps for FeO and TiO2. The Moon was divided into five (5) provinces as a balance of the needs of analysis requirements and simplicity. Division of global TiO2 weight percentages in the megaregolith /subsurface five provinces was matching the observed distribution of that at the surface. In contrast, division of lunar FeO into 5 Provinces reveals unexpectedly elevated iron concentrations (3.8 to 6.4%) in some areas of the Highland megaregolith. This Province of elevated iron oxide is termed “Highland II”

    The Time of Beauty

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    For Levinson, the Keats who thus suffers is our angel of history as described by Benjamin - face turned to the past, blown irresistibly into the future - and, in the later work especially, he reappears as the avenging angel who turns the instruments of domination against the culture that wields them.5 A postulate common in the boom years of the new historicism, best captured by Fredric Jameson's famous remark that "History is what hurts," maintained that the force of "history" is chiefly made manifest in forms of affective "hurt," trauma, and so forth.6 Where this is the case, the beautiful may signify no more than as the possibility of momentary consolation or the utopianism of a perpetually deferred redemption of time. Whether this work takes its cue from Newell Ford's description of Keatsian beauty as "prefigurati ve truth," Paul de Man's characterization of Keats's imagination as largely "prospective" in its orientation, or Patricia Parker's account of the "perpetual 'à venir in Keats," it is the forward-looking poet whose voice has most often been claimed for politics.7 Hazlitt's Essay on the Principles of Human Action furnishes a guidebook for the ethical dimensions of this self-divesting orientation towards futurity; the negatively capable chameleon poet is hailed as its literary embodiment

    Mary A. Favret, War at a Distance: Romanticism and the Making of Modern Wartime: a Review

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    Mary Favret’s War at a Distance: Romanticism and the Making of Modern Wartime is a brilliant, beautifully written book on the experience of war in British Romantic writing. Offering intricate close readings of Cowper, Wordsworth, Austen, Coleridge, and others, Favret situates these canonical writers in relation to large historical contexts: writings in a prophetic mode by Robert Brothers and Captain Charles W. Pasley, 18th century weather history, and British paintings of colonial India, to name a few. Beyond the texts and images of the Romantic period. War at a Distance moves with impressive sweep between wartimes past and present, from the Revolution and Napoleonic conflicts of two centuries ago to the first and second Gulf Wars of the 20th and 21st centuries. War at a Distance is a stirring and powerful meditation on what it means to live in a time of war

    Statin use and risk of community acquired pneumonia in older people: population based case-control study

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    Objective To test the hypothesis that hydroxymethyl glutaryl coenzyme A reductase inhibitors (statins) may decrease the risk of community acquired pneumonia

    Design and Implementation of Phase Locked Loop for Distributed Generation Systems

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    This project work concentrates on design and implementation of grid frequency synchronization of three phase inverter fed grid connected system. Initially, three phase inverter with sinusoidal PWM technique has been simulated with MATLAB/Simulink for RL load. As a next step, the design of LC filter has been carried out to generate sinusoidal waveform because the grid is subjected to disturbance as modulating wave frequency modifications, it is obligatory to preserve the frequency of grid linked to strength gadget at 50 Hz. The Grid frequency synchronization alongside amplitude and phase perspective of grid, via segment locked loop method has been supplied. The entire setup is implemented in real time by generating sine PWM pulses with the help of Arduino ATmega328P microcontroller

    HST/ACS Emission Line Imaging of Low Redshift 3CR Radio Galaxies I: The Data

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    We present 19 nearby (z<0.3) 3CR radio galaxies imaged at low- and high-excitation as part of a Cycle 15 Hubble Space Telescope snapshot survey with the Advanced Camera for Surveys. These images consist of exposures of the H-alpha (6563 \AA, plus [NII] contamination) and [OIII] 5007 \AA emission lines using narrow-band linear ramp filters adjusted according to the redshift of the target. To facilitate continuum subtraction, a single-pointing 60 s line-free exposure was taken with a medium-band filter appropriate for the target's redshift. We discuss the steps taken to reduce these images independently of the automated recalibration pipeline so as to use more recent ACS flat-field data as well as to better reject cosmic rays. We describe the method used to produce continuum-free (pure line-emission) images, and present these images along with qualitative descriptions of the narrow-line region morphologies we observe. We present H-alpha+[NII] and [OIII] line fluxes from aperture photometry, finding the values to fall expectedly on the redshift-luminosity trend from a past HST/WFPC2 emission line study of a larger, generally higher redshift subset of the 3CR. We also find expected trends between emission line luminosity and total radio power, as well as a positive correlation between the size of the emission line region and redshift. We discuss the associated interpretation of these results, and conclude with a summary of future work enabled by this dataset.Comment: 18 pages, 12 figures, accepted for publication in ApJ

    Dispersing the Mists: An Experimental History of Medicine Study into the Quality of Volatile Inhalations

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    This document is the Accepted Manuscript version. The final publication is available from Mary Ann Liebert, Inc. Publishers at https://doi.org/10.1089/jamp.2016.1357.Background: Dr. Nelson's Improved Inhaler was first marketed with an advertisement in The Lancet in 1865. Revolutionary at the time for its ease of use and patient-friendliness, the inhaler is still in use for self-treatment by many all over the world. On the occasion of its 150th anniversary, this study reports an experimental historical medicine approach to identify evidence for the quality of vapor inhalers. Methods: Through accessing reviews of the device's use by the contemporary medical establishment, it was established that Dr. Nelson's Inhaler enjoyed a reputation of quality and efficacy among reputable physicians generating empirical evidence of clinical performance. There was a general absence of product performance tests during this period. Therefore, modern inhalation performance testing was applied to test the aerosol delivery performance for Friars' Balsam, and its key chemical constituent, benzoic acid (BA). Results: A respirable dose of 59.9 ± 9.0 μg of BA was aerosolized in a 10 minutes period from a dose of 3.3 mL Friars' Balsam (equivalent to 35.1 ± 0.2 mg of BA) in 375 mL of steaming water using the glass twin stage impinger at a flow rate of 60 L·min−1. The respirable dose from a standardized aqueous BA inhalation formulation increased from 115.9 ± 10.6 to 200.2 ± 19.9 μg by increasing the simulated inhalation period from 5 to 10 minutes. When tested with a simulated inhalation maneuver (500 mL tidal volume, 13 minutes−1 respiration rate, 1:2 inspiratory:expiratory ratio) a respirable dose of 112.8 ± 40.3 μg was produced. Conclusions: This work has highlighted the potential for aerosol drug delivery using steam inhalers that are popular with patients. Physicians should therefore be aware of the potential for lung dosing with irritants when patients self-medicate using the Nelson Inhaler with vaporizing formulations such as Friars' Balsam.Peer reviewedFinal Accepted Versio

    Engaging with issues of emotionality in mathematics teacher education for social justice

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    This article focuses on the relationship between social justice, emotionality and mathematics teaching in the context of the education of prospective teachers of mathematics. A relational approach to social justice calls for giving attention to enacting socially-just relationships in mathematics classrooms. Emotionality and social justice in teaching mathematics variously intersect, interrelate or interweave. An intervention, usng creative action methods, with a cohort of prospective teachers addressing these issues is described to illustrate the connection between emotionality and social justice in the context of mathematics teacher education. Creative action methods involve a variety of dramatic, interactive and experiential tools that can promote personal and group engagement and embodied reflection. The intervention aimed to engage the prospective teachers with some key issues for social justice in mathematics education through dialogue about the emotionality of teaching and learning mathematics. Some of the possibilities and limits of using such methods are considered

    A study of patent thickets

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    Report analysing whether entry of UK enterprises into patenting in a technology area is affected by patent thickets in the technology area

    Principal role of adenylyl cyclase 6 in K+ channel regulation and vasodilator signalling in vascular smooth muscle cells

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    AIMS: Membrane potential is a key determinant of vascular tone and many vasodilators act through the modulation of ion channel currents [e.g. the ATP-sensitive potassium channel (K(ATP))] involved in setting the membrane potential. Adenylyl cyclase (AC) isoenzymes are potentially important intermediaries in such vasodilator signalling pathways. Vascular smooth muscle cells (VSMCs) express multiple AC isoenzymes, but the reason for such redundancy is unknown. We investigated which of these isoenzymes are involved in vasodilator signalling and regulation of vascular ion channels important in modulating membrane potential. METHODS AND RESULTS: AC isoenzymes were selectively depleted (by >75%) by transfection of cultured VSMCs with selective short interfering RNA sequences. AC6 was the predominant isoenzyme involved in vasodilator-mediated cAMP accumulation in VSMCs, accounting for ∼60% of the total response to β-adrenoceptor (β-AR) stimulation. AC3 played a minor role in β-AR signalling, whereas AC5 made no significant contribution. AC6 was also the principal isoenzyme involved in β-AR-mediated protein kinase A (PKA) signalling (determined using the fluorescent biosensor for PKA activity, AKAR3) and the substantial β-AR/PKA-dependent enhancement of K(ATP) current. K(ATP) current was shown to play a vital role in setting the resting membrane potential and in mediating the hyperpolarization observed upon β-AR stimulation. CONCLUSION: AC6, but not the closely related AC5, plays a principal role in vasodilator signalling and regulation of the membrane potential in VSMCs. These findings identify AC6 as a vital component in the vasodilatory apparatus central to the control of blood pressure
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