44 research outputs found
RĂ©servoir extra-digestif dâentĂ©robactĂ©ries productrices de bĂȘtalactamase Ă spectre Ă©largi chez des patients non infectĂ©s: Ă©tude Ă partir dâune recherche systĂ©matique dans les urines et dâautres prĂ©lĂšvements Ă visĂ©e diagnostique
Notre objectif Ă©tait dâĂ©tudier le rĂ©servoir extra-digestif dâentĂ©robactĂ©ries productrices de ÎČ-lactamases Ă spectre Ă©largi (EBLSE) en les recherchant dans des prĂ©lĂšvements Ă visĂ©e diagnostique (PVD) pour lesquels les colonies bactĂ©riennes isolĂ©es sur les milieux de cultures utilisĂ©s ne sont pas obligatoirement analysĂ©es (identification bactĂ©rienne et antibiogramme) en routine. Pendant une pĂ©riode de 5 semaines, des identifications et des antibiogrammes ont Ă©tĂ© rĂ©alisĂ©s de maniĂšre systĂ©matique pour les colonies correspondant Ă des entĂ©robactĂ©ries isolĂ©es dans certains PVD comme les urines, les prĂ©lĂšvements respiratoires, et un groupe de prĂ©lĂšvements appelĂ© âdiversâ. Les prĂ©lĂšvements pour lesquels un antibiogramme a Ă©tĂ© rĂ©alisĂ© conformĂ©ment Ă la pratique de routine du laboratoire ont Ă©tĂ© considĂ©rĂ©s comme infectĂ©s. Les prĂ©lĂšvements pour lesquels les entĂ©robactĂ©ries ont Ă©tĂ© recherchĂ©es et Ă©tudiĂ©es suivant le protocole de lâĂ©tude ont Ă©tĂ© considĂ©rĂ©s comme colonisĂ©s. Au cours de lâĂ©tude, 2 312 urines, 327 prĂ©lĂšvements respiratoires et 1 887 prĂ©lĂšvements divers ont Ă©tĂ© envoyĂ©s au laboratoire. Parmi les 114 urines colonisĂ©es par au moins une entĂ©robactĂ©rie, 13 (11,4 %) comportaient une EBLSE, alors que cette proportion Ă©tait de 5,1 % (35/682) dans les urines infectĂ©es (p < 0,01). Parmi les prĂ©lĂšvements respiratoires et divers, 3 EBLSE ont Ă©tĂ© isolĂ©es dans 55 prĂ©lĂšvements colonisĂ©s par au moins une entĂ©robactĂ©rie. Au total, la recherche systĂ©matique dâEBLSE dans les PVD a permis une augmentation de 27,7 % du nombre de patients identifiĂ©s comme porteurs de ces bactĂ©ries. Dâautres Ă©tudes pourraient ĂȘtre utiles pour Ă©valuer lâintĂ©rĂȘt de mettre en place une telle stratĂ©gie comme alternative au dĂ©pistage rectal habituellement pratiquĂ©
Direct comparison of phase-space distributions of K- and K+ mesons in heavy-ion collisions at SIS energies - evidence for in-medium modifications of kaons ?
The ratio of K- to K+ meson yields has been measured in the systems RuRu at
1.69 A GeV, Ru+Zr at 1.69 A GeV, and Ni+Ni at 1.93 A GeV incident beam kinetic
energy. The yield ratio is observed to vary across the measured phase space.
Relativistic transport-model calculations indicate that the data are best
understood if in-medium modifications of the kaons are taken into account.Comment: 14 pages including 3 figure
BAs and boride III-V alloys
Boron arsenide, the typically-ignored member of the III-V arsenide series
BAs-AlAs-GaAs-InAs is found to resemble silicon electronically: its Gamma
conduction band minimum is p-like (Gamma_15), not s-like (Gamma_1c), it has an
X_1c-like indirect band gap, and its bond charge is distributed almost equally
on the two atoms in the unit cell, exhibiting nearly perfect covalency. The
reasons for these are tracked down to the anomalously low atomic p orbital
energy in the boron and to the unusually strong s-s repulsion in BAs relative
to most other III-V compounds. We find unexpected valence band offsets of BAs
with respect to GaAs and AlAs. The valence band maximum (VBM) of BAs is
significantly higher than that of AlAs, despite the much smaller bond length of
BAs, and the VBM of GaAs is only slightly higher than in BAs. These effects
result from the unusually strong mixing of the cation and anion states at the
VBM. For the BAs-GaAs alloys, we find (i) a relatively small (~3.5 eV) and
composition-independent band gap bowing. This means that while addition of
small amounts of nitrogen to GaAs lowers the gap, addition of small amounts of
boron to GaAs raises the gap (ii) boron ``semi-localized'' states in the
conduction band (similar to those in GaN-GaAs alloys), and (iii) bulk mixing
enthalpies which are smaller than in GaN-GaAs alloys. The unique features of
boride III-V alloys offer new opportunities in band gap engineering.Comment: 18 pages, 14 figures, 6 tables, 61 references. Accepted for
publication in Phys. Rev. B. Scheduled to appear Oct. 15 200
Sideward flow of K+ mesons in Ru+Ru and Ni+Ni reactions near threshold
Experimental data on K+ meson and proton sideward flow measured with the FOPI
detector at SIS/GSI in the reactions Ru+Ru at 1.69 AGeV and Ni+Ni at 1.93 AGeV
are presented. The K+ sideward flow is found to be anti-correlated (correlated)
with the one of protons at low (high) transverse momenta. When compared to the
predictions of a transport model, the data favour the existence of an in-medium
repulsive K+ nucleon potential.Comment: 16 pages Revtex, 3 ps-figures, submitted to Phys. Lett.
The HERMES Spectrometer
The HERMES experiment is collecting data on inclusive and semi-inclusive deep inelastic scattering of polarised positrons from polarised targets of Il, D, and He-3. These data give information on the spin structure of the nucleon. This paper describes the forward angle spectrometer built for this purpose. The spectrometer includes numerous tracking chambers (micro-strip gas chambers, drift and proportional chambers) in front of and behind a 1.3 T.m magnetic field, as well as an extensive set of detectors for particle identification (a lead-glass calorimeter, a pre-shower detector, a transition radiation detector, and a threshold Cherenkov detector). Two of the main features of the spectrometer are its good acceptance and identification of both positrons and hadrons, in particular pions. These characteristics, together with the purity of the targets, are allowing HERMES to make unique contributions to the understanding of how the spins of the quarks contribute to the spin of the nucleon. (C) 1998 Elsevier Science B.V. All rights reserved
Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.
BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362