Charge dependence of NN→dπNN\to d\pi

We calculate the isospin symmetry violating effects to the reactions $pp\rightarrow d\pi ^+$ and $np\rightarrow d\pi ^0$ arising from the different hadron masses and from the Coulomb interaction between the positive pion and the deuteron. These effects are large enough in the cross section and analyzing power $A_y$ that they should be taken into account in comparisons of accurate experiments in different charge channels.Comment: 10 pages plus 2 figures, submitted to Phys. Lett.

Design and performance of a high-resolution frictional force microscope with quantitative three-dimensional force sensitivity

Quantum Matter and Optic

Charge independence studied in NN→dπNN\to d\pi reactions

We review to what extent charge independence breaking (\emph{CIB}) in isospin related reactions of the type $NN\to d\pi$ can or could be seen in existing data. In doing this we present fits to global and threshold cross sections including most recent data. Applying these we point out the probable impossibility to make model independent predictions even based solely on the different threshold energies and the well known $pp\to d\pi^+$. A possible discrepancy is seen between the $np\to d\pi^0$ and $pp\to d\pi^+$ data, which may require invoking explicitly isospin symmetry breaking interactions.Comment: 20 pages, 12 picture

Variations in IB1/JIP1 expression regulate susceptibility of beta-cells to cytokine-induced apoptosis irrespective of C-Jun NH2-terminal kinase signaling.

We previously reported that interleukin-1beta (IL-1beta) alone does not cause apoptosis of beta-cells, whereas when combined with gamma-interferon (IFN-gamma) and tumor necrosis factor-alpha (TNF-alpha), it exerts a distinct apoptotic effect. Studies in beta-cell lines indicated that IL-1beta reduced expression of islet brain (IB)-1/JNK interacting protein (JIP)-1, a JNK scaffold protein with antiapoptotic action. We examined whether variations in IB1/JIP-1 expression in purified primary beta-cells affect their susceptibility to cytokine-induced apoptosis. Exposure to IL-1beta for 24 h decreased cellular IB1/JIP-1 content by 66 +/- 17%; this IL-1beta effect was maintained in the presence of TNF-alpha + IFN-gamma, which did not influence IB1/JIP-1 levels by themselves. Addition of IL-1beta to TNF-alpha + IFN-gamma increased apoptosis from 20 +/- 2% to 59 +/- 5%. A similar increase in TNF-alpha + IFN-gamma-induced apoptosis was produced by adenoviral expression of antisense IB1/JIP-1 and was not further enhanced by addition of IL-1beta, indicating that IL-1beta-mediated suppression of IB1/JIP-1 in beta-cells increases their susceptibility to cytokine-induced apoptosis. However, adenovirally mediated overexpression of IB1/JIP-1 also potentiated TNF-alpha + IFN-gamma-induced apoptosis, suggesting that the antiapoptotic effect of IB1/JIP-1 depends on well-defined cellular levels. We conclude that the IB1/JIP-1 level in beta-cells can control their susceptibility to apoptosis independent of JNK signaling

A brief educational intervention using acceptance and commitment therapy: Four injured athletes' experiences

The purpose of this study was to research the experiences of four injured athletes during their rehabilitation from ACL injuries and to examine the potential usefulness of an adapted ACT intervention in addressing individuals' adherence to rehabilitation protocols and their general psychological well-being. We investigated the usefulness of a brief, 4-session ACT program adapted for educational purposes and presented data as case studies. The case studies suggested that (a) the injured athletes experienced a multitude of private events immediately following injury, throughout their recovery, and when approaching a full return to sport; (b) the injured athletes typically avoided these private events and engaged in emotion-driven behaviors; (c) an adapted ACT approach for educational purposes could be useful on at least a basic level to help injured athletes accept private events, commit to rehabilitation behaviors, and have some certainty about returning to sport; and (d) more could be done to address the needs of injured athletes beyond the structure of our 4-session educational intervention. We concluded that the ACT-based intervention, to a certain extent, educated injured athletes about how to meet the challenges of their recoveries and how to commit to their rehabilitations, as well as to exhibit behaviors that would potentially permit their successful reentries to sport

First-Principles Atomic-Scale Study of Superlow Friction

Chapter 1