Very low pressure pyrolysis of phenylacetic acid

A Kinetic study of the very low pressure thermolysis of phenylacetic acid above 900 K reveals that its decomposition occurs in a concerted manner, yielding toluene and carbon dioxide, probably via a four-centre transition state [reaction (1)] [graphic omitted] with log[k_∞(1)/s^(–1)]=[(13 ± 0.3)–(12 200 ± 500)]/T

Unreal memories. La imagen colectiva de la arquitectura en redes sociales visuales

[Abstract] Images of architecture spread quickly on visual social networks that gain interest to disseminate and communicate architecture. For this reason, it is a must to diagnose the social construction of the image of architecture, to explore the restrictions and publication formats of the platform, to identify the reaction and dissemination habits in relation to the visual features of photography and to delve into the possibilities and the risks introduced by artificial intelligence systems. The research method follows a cognitive association approach through various graphic case studies on Instagram. The exploratory design to approach the role of the image to communicate architecture in visual social media arises from the concept of the fragment and the biased vision, a division required due to the nature of related image suggestions as a browsing method on Instagram. The findings identify opportunities and action strategies to complement the contents that build the collective image of architecture adapted to the logic of the new scenario.[Resumen] Las imágenes de arquitectura se propagan rápidamente en las redes sociales visuales que ganan interés para difundir y comunicar la arquitectura. Por ello, es imprescindible diagnosticar el proceso de la construcción social de la imagen de la arquitectura, explorar las restricciones y formatos de publicación de la plataforma, identificar los hábitos de reacción y difusión con relación a los rasgos visuales de la fotografía y ahondar en las posibilidades y los riesgos que introducen los sistemas de inteligencia artificial (IA). El método de investigación sigue un enfoque de asociación cognitiva a través del análisis de varios estudios de casos gráficos en Instagram. El diseño exploratorio para abordar el papel de la imagen para comunicar la arquitectura en las redes sociales visuales surge del concepto de fragmento y de la visión sesgada, división requerida por la naturaleza de las sugerencias de imágenes relacionadas como método de navegación en Instagram. Los hallazgos identifican oportunidades y estrategias de acción para complementar los contenidos que construyen la imagen colectiva de la arquitectura adaptados a la lógica del nuevo escenario

Unreal memories: La imagen colectiva de la arquitectura en redes sociales visuales

Images of architecture spread quickly on visual social networks that gain interest to disseminate and communicate architecture. For this reason, it is a must to diagnose the social construction of the image of architecture, to explore the restrictions and publication formats of the platform, to identify the reaction and dissemination habits in relation to the visual features of photography and to delve into the possibilities and the risks introduced by artificial intelligence systems. The research method follows a cognitive association approach through various graphic case studies on Instagram. The exploratory design to approach the role of the image to communicate architecture in visual social media arises from the concept of the fragment and the biased vision, a division required due to the nature of related image suggestions as a browsing method on Instagram. The findings identify opportunities and action strategies to complement the contents that build the collective image of architecture adapted to the logic of the new scenario.Las imágenes de arquitectura se propagan rápidamente en las redes sociales visuales que ganan interés para difundir y comunicar la arquitectura. Por ello, es imprescindible diagnosticar el proceso de la construcción social de la imagen de la arquitectura, explorar las restricciones y formatos de publicación de la plataforma, identificar los hábitos de reacción y difusión con relación a los rasgos visuales de la fotografía y ahondar en las posibilidades y los riesgos que introducen los sistemas de inteligencia artificial (IA). El método de investigación sigue un enfoque de asociación cognitiva a través del análisis de varios estudios de casos gráficos en Instagram. El diseño exploratorio para abordar el papel de la imagen para comunicar la arquitectura en las redes sociales visuales surge del concepto de fragmento y de la visión sesgada, división requerida por la naturaleza de las sugerencias de imágenes relacionadas como método de navegación en Instagram. Los hallazgos identifican oportunidades y estrategias de acción para complementar los contenidos que construyen la imagen colectiva de la arquitectura adaptados a la lógica del nuevo escenario

Agilometer: An Effective Implementation of Internet of Things for Agile Demand Response

Transactive based control mechanism (TCM) needs the IoT environment to fully explore flexibility potential from the end-users to offer to involved actors of the smart energy system. On the other hand, many IoT based energy management systems are already available to a market. This paper presents an ap-proach to connect the current demand-driven (top-down) energy management system (EMS) with a market-driven (bottom-up) demand response program. To this end, this paper considers multi-agent system (MAS) to realize the approach and introduces the concept and standardize design of Agilometer. It is described as an elemental agent of the approach. Proposed by authors Agilometer consists of three different functional blocks, which are formulated as an IoT platform according to the LonWorks standard. Moreover, the paper also performs an evaluation study in order to validate the proposed concept and design

The significance of c.690G>T polymorphism (rs34529039) and expression of the CEBPA gene in ovarian cancer outcome

The CEBPA gene is known to be mutated or abnormally expressed in several cancers. This is the first study assessing the clinical impact of CEBPA gene status and expression on the ovarian cancer outcome. The CEBPA gene sequence was analyzed in 118 ovarian cancer patients (44 platinum/cyclophosphamide (PC)-treated and 74 taxane/platinum (TP)-treated), both in tumors and blood samples, and in blood from 236 healthy women, using PCR-Sanger sequencing and Real-Time quantitative PCR (qPCR)-based genotyping methods, respectively. The CEBPA mRNA level was examined with Reverse Transcription quantitative PCR (RT-qPCR). The results were correlated to different clinicopathological parameters. Thirty of 118 (25.4%) tumors harbored the CEBPA synonymous c.690G>T polymorphism (rs34529039), that we showed to be related to up-regulation of CEBPA mRNA levels (p=0.0059). The presence of the polymorphism was significantly associated with poor prognosis (p=0.005) and poor response to the PC chemotherapy regimen (p=0.024). In accordance, elevated CEBPA mRNA levels negatively affected patient survival (pT, p.(Thr230Thr) (rs34529039) polymorphism of the CEBPA gene, together with up-regulation of its mRNA expression, are negative factors worsening ovarian cancer outcome. Their adverse clinical effect depends on a therapeutic regimen used, which might make them potential prognostic and predictive biomarkers for response to DNA-damaging chemotherapy

Eigenvectors under a generic perturbation: non-perturbative results from the random matrix approach

We consider eigenvectors of the Hamiltonian H0 perturbed by a generic perturbation V modelled by a random matrix from the Gaussian Unitary Ensemble (GUE). Using the super-symmetry approach we derive analytical results for the statistics of the eigenvectors, which are non-perturbative in V and valid for an arbitrary deterministic H0. Further we generalise them to the case of a random H0, focusing, in particular, on the Rosenzweig-Porter model. Our analytical predictions are confirmed by numerical simulations

Epidemiological impact of waning immunization on a vaccinated population

This is an epidemiological SIRV model based study that is de- signed to analyze the impact of vaccination in containing infection spread, in a 4-tiered population compartment comprised of susceptible, infected, recov- ered and vaccinated agents. While many models assume a lifelong protection through vaccination, we focus on the impact of waning immunization due to conversion of vaccinated and recovered agents back to susceptible ones. Two asymptotic states exist, the \disease-free equilibrium" and the \endemic equi- librium" and we express the transitions between these states as function of the vaccination and conversion rates and using the basic reproduction number. We nd that the vaccination of newborns and adults have dierent consequences on controlling an epidemic. Also, a decaying disease protection within the re- covered sub-population is not sucient to trigger an epidemic on the linear level. We perform simulations for a parameter set modelling a disease with waning immunization like pertussis. For a diusively coupled population, a transition to the endemic state can proceed via the propagation of a traveling infection wave, described successfully within a Fisher-Kolmogorov framework

Assessing Sustainability in the Shipbuilding Supply Chain 4.0: A Systematic Review

The supply chain is currently taking on a very important role in organizations seeking to improve the competitiveness and profitability of the company. Its transversal character mainly places it in an unbeatable position to achieve this role. This article, through a study of each of the key enabling technologies of Industry 4.0, aims to obtain a general overview of the current state of the art in shipbuilding adapted to these technologies. To do so, a systematic review of what the scientific community says is carried out, dividing each of the technologies into different categories. In addition, the global vision of countries interested in each of the enabling technologies is also studied. Both studies present a general vision to the companies of the concerns of the scientific community, thus encouraging research on the subject that is focused on the sustainability of the shipbuilding supply chain