Additive Manufacturing Tools to Improve the Performance of Chromatographic Approaches

Chromatography is widely applied industrially. However, some limitations are associated with its common supports, and the impossibility to fully control their structural features is particularly restrictive. Additive manufacturing (AM) is emerging as a fast, highly precise, and reproducible technology for producing chromatographic supports that can improve its performance.info:eu-repo/semantics/publishedVersio

Predicting Cetacean Distributions in the Eastern North Atlantic to Support Marine Management

Acknowledgments We thank all the volunteers for their contribution and dedication during the monitoring campaigns. This manscript is a product of the work of every observer who participated in the CETUS Project. We are extremely grateful to TRANSINSULAR, the cargo ship company that provided all the logistic support, and to the ships’ crews for their hospitality. We also thank Vasilis Valavanis for his valuable advice about the use of oceanographic variables.Peer reviewedPublisher PD

TRPV1 feed-forward sensitisation depends on COX2 upregulation in primary sensory neurons

Increased activity and excitability (sensitisation) of a series of molecules including the transient receptor potential ion channel, vanilloid subfamily, member 1 (TRPV1) in pain-sensing (nociceptive) primary sensory neurons are pivotal for developing pathological pain experiences in tissue injuries. TRPV1 sensitisation is induced and maintained by two major mechanisms; post-translational and transcriptional changes in TRPV1 induced by inflammatory mediators produced and accumulated in injured tissues, and TRPV1 activation-induced feed-forward signalling. The latter mechanism includes synthesis of TRPV1 agonists within minutes, and upregulation of various receptors functionally linked to TRPV1 within a few hours, in nociceptive primary sensory neurons. Here, we report that a novel mechanism, which contributes to TRPV1 activation-induced TRPV1-sensitisation within ~ 30 min in at least ~ 30% of TRPV1-expressing cultured murine primary sensory neurons, is mediated through upregulation in cyclooxygenase 2 (COX2) expression and increased synthesis of a series of COX2 products. These findings highlight the importance of feed-forward signalling in sensitisation, and the value of inhibiting COX2 activity to control pain, in nociceptive primary sensory neurons in tissue injuries

A dataset of cetacean occurrences in the Eastern North Atlantic

The CETUS project is a cetacean monitoring program that takes advantage of cargo ships to undertake survey routes between Continental Portugal, Macaronesian archipelagos and West Africa. From 2012 to 2017, over 50 volunteers participated in the program, actively surveying more than 124.000 km, mostly beyond national jurisdictions in the high seas, for which little or no previous data existed. In total, the collection comprises 3058 georeferenced transect lines and 8913 positions, which are associated with 2833 cetacean sightings, 362 occurrences of other pelagic megafauna, 5260 estimates of marine traffic and 8887 weather observations. This dataset may provide new insights into the distribution of marine mammals in the Eastern North Atlantic and was published following the OBIS-ENV-DATA format (with the most recent biodiversity data standards at the time of writing). Consequently, it may serve as a model for similar visual line transect data collections yet to be published.Portuguese national funding agency for science, research and technology (FCT) /BD/100606/2014info:eu-repo/semantics/publishedVersio

A large community outbreak of Legionnaires’ disease in Vila Franca de Xira, Portugal, October to November 2014

An outbreak of Legionnaires’ disease with 334 confirmed cases was identified on 7 November 2014 in Vila Franca de Xira, Portugal and declared controlled by 21 November. Epidemiological, environmental and microbiological analysis identified industrial wet cooling systems to be the probable source of infection. Preliminary results from sequence-based typing of clinical specimens and environmental isolates confirmed this link. A series of meteorological phenomena are likely to have contributed to the scale of this outbreak

Integrated Design in Welding and Incremental Forming: Material Model Calibration for Friction Stir Welded Blanks

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Método dos Elementos Finitos: técnicas de simulação numérica em engenharia

Resumo indisponível.publishe

Anthropometric characteristics of male rink hockey goalkeeper's according to their competitive level

Objective: Evaluate the anthropometric characteristics of male rink hockey goalkeepers, and to compare the variation according to their competitive level (international vs. non-international). Methods: Body mass, stature, sitting height, arm span, waist and hip circumferences and four skinfold measurements (triceps, medial calf, subscapular and supraspinale) of international (n = 12) and non-international (n = 23) goalkeepers were taken. Body mass index (BMI, weight/height 2), the sum of four skinfolds, the sitting height/stature ratio, waist/hip ratio and the relative arm span were also calculated. Results: International rink hockey goalkeepers have lower values of subcutaneous adiposity for the sum of the four skinfolds (P = 0.042; d = 0.76) particularly in the triceps (P = 0.016; d = 0.87) and are taller than non-international goalkeepers (+3.8 cm [2.2%]; 180.5 ± 7.0 vs. 176.6 ± 4.8 cm; t = 1.920; P = 0.064; d = 0.65). Conclusion: The findings could indicate that stature and body fat may have important implications for scouts regarding the selection process and coaches that work with players on developing performance. Future research should investigate the extent to which different anthropometric measures influence performance in rink hockey goalkeepers

Using educational networks to promote internationalization experiences in physiotherapy education

Introduction and Objectives: The Academic Network of Health Sciences of Lusofonia (RACS - racslusofonia.org) was created in 2016, with the mission of promoting training and scientific cooperation in health sciences, between higher education institutions and research centers in different countries and Portuguese speaking communities. Within the Physiotherapy Education Group of RACS we develop a project with a set of activities, developed along the academic path of the physiotherapy students, which allow them to be exposed progressively to the international context. Methods: During the 2021/22 academic year, 10 institutions involving 103 Physiotherapy students from 6 different countries (Portugal, Brazil, Mozambique, Cabo Verde, Angola, and São Tomé e Principe) participate in this project. Students are asked, over a period of 2 months, to carry out at least 2 online meetings within an international group to discuss topics related to the reality of education and the practice of Physiotherapists. As a result, students submit an individual reflection on the most relevant points that were identified in this sharing process. In each of the participating institutions, there was a teacher responsible for preparing, supporting, and evaluating the students' reflections. Results: To assess the impact and satisfaction of the students with activity, an online questionnaire (10 questions) was used, with several dimensions (preparation, performance, and global opinion) where a response rate of 83% was obtained (n=86). Regarding the answers, 93% considered that the objectives of the activity were clear and attainable and that the support materials were adequate (83%). Regarding meetings with international peers, 70% said that communication was easy during the meetings and that the proposed objectives were achieved (91%). Concerning the impact of the activity, 94% considered that the activity contributes to a better understanding of the international context of teaching and practice of physiotherapists, stressing that it should continue to be carried out within the scope of the physiotherapy course (89%). Conclusion(s): The overall reflexion from the students and teachers involved was very positive, reinforcing the importance of this activity and identifying areas of improvement related to student recruitment and support throughout this process. Based on the results, it seems important for us to carry out this project as it facilitates students’ early exposure to international contexts, which may facilitate the development of skills that allow them to play a more active and global professional role.info:eu-repo/semantics/publishedVersio

Using educational networks to promote internationalization experiences in physiotherapy education

Introduction and Objectives: The Academic Network of Health Sciences of Lusofonia (RACS - racslusofonia.org) was created in 2016, with the mission of promoting training and scientific cooperation in health sciences, between higher education institutions and research centers in different countries and Portuguese speaking communities. Within the Physiotherapy Education Group of RACS we develop a project with a set of activities, developed along the academic path of the physiotherapy students, which allow them to be exposed progressively to the international context. Methods: During the 2021/22 academic year, 10 institutions involving 103 Physiotherapy students from 6 different countries (Portugal, Brazil, Mozambique, Cabo Verde, Angola, and São Tomé e Principe) participate in this project. Students are asked, over a period of 2 months, to carry out at least 2 online meetings within an international group to discuss topics related to the reality of education and the practice of Physiotherapists. As a result, students submit an individual reflection on the most relevant points that were identified in this sharing process. In each of the participating institutions, there was a teacher responsible for preparing, supporting, and evaluating the students' reflections. Results: To assess the impact and satisfaction of the students with activity, an online questionnaire (10 questions) was used, with several dimensions (preparation, performance, and global opinion) where a response rate of 83% was obtained (n=86). Regarding the answers, 93% considered that the objectives of the activity were clear and attainable and that the support materials were adequate (83%). Regarding meetings with international peers, 70% said that communication was easy during the meetings and that the proposed objectives were achieved (91%). Concerning the impact of the activity, 94% considered that the activity contributes to a better understanding of the international context of teaching and practice of physiotherapists, stressing that it should continue to be carried out within the scope of the physiotherapy course (89%). Conclusion(s): The overall reflexion from the students and teachers involved was very positive, reinforcing the importance of this activity and identifying areas of improvement related to student recruitment and support throughout this process. Based on the results, it seems important for us to carry out this project as it facilitates students’ early exposure to international contexts, which may facilitate the development of skills that allow them to play a more active and global professional role.N/