7 research outputs found
A three-generation study on the association of tobacco smoking with asthma
Background: Mothers' smoking during pregnancy increases asthma risk in their offspring. There is some evidence that grandmothers' smoking may have a similar effect, and biological plausibility that fathers' smoking during adolescence may influence offspring's health through transmittable epigenetic changes in sperm precursor cells. We evaluated the three-generation associations of tobacco smoking with asthma. Methods: Between 2010 and 2013, at the European Community Respiratory Health Survey III clinical interview, 2233 mothers and 1964 fathers from 26 centres reported whether their offspring (aged <= 51 years) had ever had asthma and whether it had coexisted with nasal allergies or not. Mothers and fathers also provided information on their parents' (grandparents) and their own asthma, education and smoking history. Multilevel mediation models within a multicentre three-generation framework were fitted separately within the maternal (4666 offspring) and paternal (4192 offspring) lines. Results: Fathers' smoking before they were 15 [relative risk ratio (RRR) = 1.43, 95% confidence interval (CI): 1.01-2.01] and mothers' smoking during pregnancy (RRR = 1.27, 95% CI: 1.01-1.59) were associated with asthma without nasal allergies in their offspring. Grandmothers' smoking during pregnancy was associated with asthma in their daughters [odds ratio (OR) = 1.55, 95% CI: 1.17-2.06] and with asthma with nasal allergies in their grandchildren within the maternal line (RRR = 1.25, 95% CI: 1.02-1.55). Conclusions: Fathers' smoking during early adolescence and grandmothers' and mothers' smoking during pregnancy may independently increase asthma risk in offspring. Thus, risk factors for asthma should be sought in both parents and before conception
Nouveaux regards sur lâĂ©ducation et la formation : contributions des jeunes chercheurs du CIDEF 2020
Ce numĂ©ro rassemble six travaux issus des cinquante communications orales et affichĂ©es du Colloque doctoral international de lâĂ©ducation et de la formation (CIDEF 2020), prĂ©sentĂ©es Ă distance les 27 et 28 octobre 2020. Si chacun de ces articles propose un Ă©clairage sur les enjeux pour lâĂ©ducation et la formation de demain, ils traitent cette thĂ©matique Ă partir dâobjets trĂšs diffĂ©rents et de mĂ©thodes variĂ©es : les politiques Ă©ducatives et les politiques de formation, les usagers de lâĂ©ducation et de la formation, ainsi que lâanalyse de pratiques. La complĂ©mentaritĂ© de ces travaux nous offre une vision large de la richesse offerte par cette discipline de recherche. Une premiĂšre partie rend compte de la rĂ©alitĂ© des pratiques lorsquâelles sont imposĂ©es institutionnellement et tĂ©moigne dâune volontĂ© de comprendre les modalitĂ©s dâenseignement et de formation actuelles. Dans le prolongement de ce travail, la deuxiĂšme partie de ce numĂ©ro propose des articles sâintĂ©ressant Ă des initiatives pĂ©dagogiques et interroge leurs effets sur les pratiques des professionnels de lâĂ©ducation et de la formation mais Ă©galement sur lâapprentissage des bĂ©nĂ©ficiaires. This issue offers six studies from the fifty oral and written presentations of the International Doctoral Conference on Education (CIDEF 2020), presented online on 27 and 28 October 2020. While each of these articles sheds light on the challenges for tomorrow's education, they deal with this theme from very different objects and methods: educational policies, users of education, as well as the analysis of practices. The complementarity of this work offers us a broad vision of the richness offered by this research discipline. A first part reflects the reality of practices when they are imposed institutionally and shows a desire to understand current teaching methods. As an extension of this work, the second part of this issue offers articles on pedagogical initiatives. It also questions their effects on the practices of education professionals but also on the learning of beneficiaries
Exclusive and complete introduction of amino groups and their N-sulfo and N-carboxymethyl groups into the 6-position of cellulose without the use of protecting groups
Mothers' smoking during pregnancy increases asthma risk in their offspring. There is some evidence that grandmothers' smoking may have a similar effect, and biological plausibility that fathers' smoking during adolescence may influence offspring's health through transmittable epigenetic changes in sperm precursor cells. We evaluated the three-generation associations of tobacco smoking with asthma.; Between 2010 and 2013, at the European Community Respiratory Health Survey III clinical interview, 2233 mothers and 1964 fathers from 26 centres reported whether their offspring (aged â€51âyears) had ever had asthma and whether it had coexisted with nasal allergies or not. Mothers and fathers also provided information on their parents' (grandparents) and their own asthma, education and smoking history. Multilevel mediation models within a multicentre three-generation framework were fitted separately within the maternal (4666 offspring) and paternal (4192 offspring) lines.; Fathers' smoking before they were 15 [relative risk ratio (RRR)â=â1.43, 95% confidence interval (CI): 1.01-2.01] and mothers' smoking during pregnancy (RRRâ=â1.27, 95% CI: 1.01-1.59) were associated with asthma without nasal allergies in their offspring. Grandmothers' smoking during pregnancy was associated with asthma in their daughters [odds ratio (OR)â=â1.55, 95% CI: 1.17-2.06] and with asthma with nasal allergies in their grandchildren within the maternal line (RRRâ=â1.25, 95% CI: 1.02-1.55).; Fathers' smoking during early adolescence and grandmothers' and mothers' smoking during pregnancy may independently increase asthma risk in offspring. Thus, risk factors for asthma should be sought in both parents and before conception.; European Union (Horizon 2020, GA-633212)
A three-generation study on the association of tobacco smoking with asthma
Background: Mothers' smoking during pregnancy increases asthma
risk in their offspring. There is some evidence that
grandmothers' smoking may have a similar effect, and biological
plausibility that fathers' smoking during adolescence may
influence offspring's health through transmittable epigenetic
changes in sperm precursor cells. We evaluated the
three-generation associations of tobacco smoking with asthma.
Methods: Between 2010 and 2013, at the European Community
Respiratory Health Survey III clinical interview, 2233 mothers
and 1964 fathers from 26 centres reported whether their
offspring (aged </=51 years) had ever had asthma and whether
it had coexisted with nasal allergies or not. Mothers and
fathers also provided information on their parents'
(grandparents) and their own asthma, education and smoking
history. Multilevel mediation models within a multicentre
three-generation framework were fitted separately within the
maternal (4666 offspring) and paternal (4192 offspring) lines.
Results: Fathers' smoking before they were 15 [relative risk
ratio (RRR) = 1.43, 95% confidence interval (CI): 1.01-2.01] and
mothers' smoking during pregnancy (RRR = 1.27, 95% CI:
1.01-1.59) were associated with asthma without nasal allergies
in their offspring. Grandmothers' smoking during pregnancy was
associated with asthma in their daughters [odds ratio (OR) =
1.55, 95% CI: 1.17-2.06] and with asthma with nasal allergies in
their grandchildren within the maternal line (RRR = 1.25, 95%
CI: 1.02-1.55). Conclusions: Fathers' smoking during early
adolescence and grandmothers' and mothers' smoking during
pregnancy may independently increase asthma risk in offspring.
Thus, risk factors for asthma should be sought in both parents
and before conception