La educación musical en un centro unitario

Este estudio trata de destacar el valor de la educación en el medio rural y más concretamente de la práctica artística. Educar en el medio rural en referencia a las ventajas que supone para el alumno el desarrollo de la actividad de enseñanza/aprendizaje en un entorno privilegiado tan motivador, despertando la curiosidad como clave del aprendizaje. Así mismo la originada por la existencia de alumnado de diferentes edades en el contexto del grupo-clase, que fundamenta el concepto de multigraduación y que da sentido a las relaciones y al funcionamiento de los grupos de alumnado rural. Las conclusiones hacen visibles las ventajas que tiene para el alumnado la elevada heterogeneidad de los grupos multigrado. La Educación Musical a la que se otorga un gran valor en los primeros años de vida adquiriendo necesaria presencia en las aulas y proporcionando el desarrollo de múltiples capacidades que abarcan el plano personal y social, estético…. Será básico para este estudio desvelar los entramados de la práctica vocal e instrumental en las aulas unitarias,cuyo marco experimental, lejos de resultar una tarea sencilla, requiere de una gran elaboración por parte del docente, a la par que proporciona multitud de posibilidades.Grado en Educación Primari

A Postprocessing methodology for direct normal irradiance forecasting using cloud information and aerosol load forecasts

A method for direct normal irradiance (DNI) forecasting for specific sites is proposed. It is based on the combination of a numerical weather prediction (NWP) model, which provides cloud information, with radiative transfer simulations fed with external aerosol forecasts. The NWP model used is the ECMWF Integrated Forecast System, and the radiative transfer information has been obtained from the Library of Radiative Transfer (libRadtran). Two types of aerosol forecasts have been tested: the global Monitoring Atmospheric Composition and Climate (MACC) model, which predicts five major components of aerosols, and the Dust Regional Atmospheric Model (BSC-DREAM8b) added to a fixed background calculated as the 20th percentile of the monthly mean of AERONET 2.0 observations from a different year. The methodology employed is valid for all meteorological situations, providing a stable and continuous DNI curve. The performance of the combined method has been evaluated against DNI observations and compared with the pure ECMWF forecasts at eight locations in the southern half of mainland Spain and the Canary Islands, which received high loadings of African dust for 2013 and 2014. Results for 1-day forecasts are presented. Although clouds play a major role, aerosols have a significant effect, but at shorter time scales. The combination of ECMWF and MACC forecasts gives the best global results, improving the DNI forecasts in events with high aerosol content. The regional BSC-DREAM8b yields good results for some extremely high dust conditions, although more reliable predictions, valid for any aerosol conditions, are provided by the MACC model

Barnacle Allergy in the Context of the Mites-Crustaceans-Molluscs-Cockroaches Syndrome

Introdução: A tropomiosina dos invertebrados é o pan-alergénio que une crustáceos, moluscos, aracnídeos, insectos e parasitas, encontrando-se significativa homologia de sequência entre as proteínas dos vários grupos. Os perceves são um tipo de crustáceo particularmente apreciado e consumido no nosso país; no entanto, a alergia a este crustáceo é uma situação bastante rara da qual só existe um trabalho publicado na literatura. Caso clínico: Apresentamos o caso de uma criança do sexo masculino, de 9 anos de idade, com asma brônquica, rinoconjuntivite alérgica e eczema atópico, sensibilizada a ácaros e baratas. Aos 7 anos, 10 minutos após a primeira ingestão de perceves, refere síndrome de alergia oral, angioedema periorbitário e rinoconjuntivite. Aos 8 anos, ocorreram 4 episódios semelhantes após ingestão de caracol, camarão, lula e choco (referindo ingestão prévia destes alimentos sem queixas). Aos 9 anos, refere episódio de urticária da face e angioedema periorbitário com inalação de vapores de cozedura de camarão. Foram realizados testes cutâneos por prick que se revelaram positivos para perceves, camarão, caracol, lula, choco, polvo e amêijoa em natureza, e para gamba, caranguejo e mexilhão com extractos comerciais. Os doseamentos de IgE específica sérica revelaram-se positivos para camarão, caracol, lula, polvo e amêijoa, bem como para perceves e tropomiosina recombinante. Foi efectuado SDS-PAGE immunoblotting com extracto de perceves que revelou várias fracções alergénicas com grande variação de pesos moleculares (19-88 kDa); foi ainda efectuado estudo de inibição com D. pteronyssinus, que inibiu várias fracções fixadoras de IgE no extracto de perceves. Discussão: Apresenta-se um caso raro de uma criança, com quadro de alergia respiratória associada a sensibilização a ácaros e baratas, com alergia alimentar a crustáceos –incluindo a perceves – e moluscos gastrópodes, bivalves e cefalópodes. Foram caracterizados os alergénios implicados na alergia a perceves e demonstrada a presença da tropomiosina como alergénio implicado, bem como a reactividade cruzada entre estes crustáceos e os ácaros

Detailed Classification of Swift's Gamma-Ray Bursts

Earlier classification analyses found three types of gamma-ray bursts (short, long and intermediate in duration) in the BATSE sample. Recent works have shown that these three groups are also present in the RHESSI and the BeppoSAX databases. The duration distribution analysis of the bursts observed by the Swift satellite also favors the three-component model. In this paper, we extend the analysis of the Swift data with spectral information. We show, using the spectral hardness and the duration simultaneously, that the maximum likelihood method favors the three-component against the two-component model. The likelihood also shows that a fourth component is not needed.Comment: Accepted for publication in The Astrophysical Journa

High-speed 1.55 μm operation of low-temperature-grown GaAs-based resonant-cavity-enhanced p–i–n photodiodes

We report the design, growth, fabrication, and characterization of GaAs-based high-speed p–i–n photodiodes operating at 1.55 μm. A low-temperature-grown GaAs (LT-GaAs) layer was used as the absorption layer and the photoresponse was selectively enhanced at 1.55 μm using a resonant-cavity-detector structure. The bottom mirror of the resonant cavity was formed by a highly reflecting 15-pair GaAs/AlAs Bragg mirror. Molecular-beam epitaxy was used for wafer growth, where the active LT-GaAs layer was grown at a substrate temperature of 200 °C. The fabricated devices exhibited a resonance around 1548 nm. When compared to the efficiency of a conventional single-pass detector, an enhancement factor of 7.5 was achieved. Temporal pulse-response measurements were carried out at 1.55 μm. Fast pulse responses with 30 ps pulse-width and a corresponding 3 dB bandwidth of 11.2 GHz was measured.This work was supported by NATO Grant No. SfP971970, Turkish Department of Defense Grant No.KOBRA-001, Thales JP8.04, CAM 07N/0059/2002 and ‘‘NANOSELF’’ TIC2002-04096-C03-03. E.O. acknowledges partial support received from Turkish Academy of Sciences.Peer reviewe

Barnacle Allergy: Allergen Characterization and Cross-Reactivity with Mites

Background: Barnacles are a type of seafood with worldwide distribution and abundant along the shores of temperate seas. They are particularly appreciated and regularly consumed in Portugal as well as in Spain, France and South America, but barnacle allergy is a rare condition of which there is only one reference in the indexed literature. The molecular allergens and possible cross-reactivity phenomena implicated (namely with mites) have not been established. Objective: To demonstrate the IgE-mediated allergy to barnacle and to identify the proteins implicated as well as possible cross-reactivity phenomena with mites. Methods: We report the clinical and laboratory data of five patients with documented IgE-mediated allergy to barnacle. The diagnosis was based on a suggestive clinical history combined with positive skin prick tests (SPT) to barnacle – prick to prick method. Two barnacle extracts were prepared (raw and cooked barnacle) and sodium dodecylsulphate polyacrylamide gel electrophoresis (SDS-PAGE) and IgE-immunoblotting were performed. An immunoblotting inhibition assay with Dermatophagoides pteronyssinus was also done in order to evaluate cross-reactivity. Results: All patients had mite-related asthma and the allergic rhinoconjunctivitis; they all experienced mucocutaneous symptoms. All of them had positive SPT to barnacle, and the immunoblotting showed several allergenic fractions with a wide molecular weight range (19 – 94 kDa). The D. pteronyssinus extract inhibited several IgE-binding protein fractions in the barnacle extract. Conclusions: We describe five patients with IgE-mediated barnacle allergy. We also describe a group of IgEbinding+ proteins between 30 and 75 kDa as the allergenic fractions of this type of Crustacea. Cross-reactivity with D. pteronyssinus was demonstrated in two cases

Searching for differences in Swift's intermediate GRBs

Gamma-ray bursts are usually classified through their high-energy emission into short-duration and long-duration bursts, which presumably reflect two different types of progenitors. However, it has been shown on statistical grounds that a third, intermediate population is needed in this classification scheme, although an extensive study of the properties of this class has so far not been done. The large amount of follow-up studies generated during the Swift era allows us to have a suficient sample to attempt a study of this third population through the properties of their prompt emission and their afterglows. Our study is focused on a sample of GRBs observed by Swift during its first four years of operation. The sample contains those bursts with measured redshift since this allows us to derive intrinsic properties. Intermediate bursts are less energetic and have dimmer afterglows than long GRBs, especially when considering the X-ray light curves, which are on average one order of magnitude fainter than long bursts. There is a less significant trend in the redshift distribution that places intermediate bursts closer than long bursts. Except for this, intermediate bursts show similar properties to long bursts. In particular, they follow the Epeak vs. Eiso correlation and have, on average, positive spectral lags with a distribution similar to that of long bursts. Like long GRBs, they normally have an associated supernova, although some intermediate bursts have shown no supernova component. This study shows that intermediate bursts are different from short bursts and, in spite of sharing many properties with long bursts, there are some differences between them as well. We suggest that the physical difference between intermediate and long bursts could be that for the first the ejecta are thin shells while for the latter they are thick shells.Comment: Accepted for publication in Astronomy and Astrophysics. 16 pages, 17 figures, 5 table

Preparedness needs research: How fundamental science and international collaboration accelerated the response to COVID-19

The first cluster of patients suffering from coronavirus disease 2019 (COVID-19) was identified on December 21, 2019, and as of July 29, 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections have been linked with 664,333 deaths and number at least 16,932,996 worldwide. Unprecedented in global societal impact, the COVID-19 pandemic has tested local, national, and international preparedness for viral outbreaks to the limits. Just as it will be vital to identify missed opportunities and improve contingency planning for future outbreaks, we must also highlight key successes and build on them. Concomitant to the emergence of a novel viral disease, there is a ‘research and development gap’ that poses a threat to the overall pace and quality of outbreak response during its most crucial early phase. Here, we outline key components of an adequate research response to novel viral outbreaks using the example of SARS-CoV-2. We highlight the exceptional recent progress made in fundamental science, resulting in the fastest scientific response to a major infectious disease outbreak or pandemic. We underline the vital role of the international research community, from the implementation of diagnostics and contact tracing procedures to the collective search for vaccines and antiviral therapies, sustained by unique information sharing efforts

Early individual stakeholders, first venture capital investment, and exit in the UK startup ecosystem

We create a novel, comprehensive dataset of UK-based startups with extensive information on ownership, control, and valuation. Our database provides unique descriptive evidence about the relevance of individual stakeholders in startups, particularly before the entry of venture capital institutional investors. We compare the influence of two comparable characteristics of various groups of pre-institutional individual stakeholders: size and experience. We show that the quantity as well as the experience, of founders, directors, and other individual investors correlate with the startup's type of, and value at, exit. Success results are very different across types of diversity: functional diversity appears to have a positive relationship with success whereas that of demographic diversity is negative