Factors Cause of Maternal Death in Timor-Leste

Maternal mortality was an indicator of basic health services for mothers or women of reproductive age of a country and was one of the eight Millennium Development Goals (MDGs). Factors that affect maternal mortality, among others: medical factors, non-medical factors, and health care system factors. Meanwhile, WHO (2010) reported that the cause of maternal mortality in the world is 25% of bleeding, 15% of infection/sepsis, 12% eclampsia, 13% of abortions are unsafe, 8% obstructed and ectopic pregnancy, 8% embolisms and other related issues with anesthetic problems. WHO (2010) has determined that the maternal mortality rate (MMR) in 40 countries ≥ 300 / 100,000 live births including República Democrática de Timor-Leste at 557 / 100,000 live births. Objective: This study aimed to determine the relationship between the variables of age, parity, spacing pregnancies, health behavior, and health status of mothers with maternal deaths. Methods: The study design was a cross-sectional study with a sample of 298 pregnant women in 13 districts throughout Timor-Leste. Results: Maternal deaths are caused by independent variables simultaneously and the remaining 28.0% were prescribed other factors

FRANKLINIELLA OCCIDENTALIS, F. SCHULTZEI AND F. FUSCA (THYSANOPTERA.THRIPIDAE) IN PUERTO RICO

FRANKLINIELLA OCCIDENTALIS, F. SCHULTZEI AND F. FUSCA (THYSANOPTERA: THRIPIDAE) IN PUERTO RIC

El modelo de la Atención Centrada en la Persona: Análisis descriptivo de una muestra de personas mayores con demencia en centros residenciales

Este análisis descriptivo tiene el objetivo de evaluar la calidad asistencial de una muestra de personas con demencia institucionalizadas usando el Dementia Care Mapping (DCM) como metodología de observación sistemática y de examinar la presencia de pautas asociadas a la psicología social maligna en las residencias observadas. Participaron en el estudio 73 personas con demencia ingresadas en residencias a largo plazo. Los resultados más relevantes apuntan a la presencia de una cultura de cuidados donde predomina la psicología social maligna y el DCM como un instrumento que permite analizar el comportamiento de las personas con demencia, aportando nuevas variables como el bienestar emocional, la diversidad ocupacional y la calidad de la interacción social. Se concluye que la implementación de un modelo de atención centrado en la persona puede incidir postivamente en el bienestar de las personas con demencia

Burkholderia cepacia Complex Infections Among Cystic Fibrosis Patients: Perspectives and Challenges

The Burkholderia cepacia complex (Bcc) is a group of closely related bacterial species that emerged in the 1980s as the etiological agents of severe and often lethal respiratory infections among cystic fibrosis (CF) patients. After several outbreaks in CF centers in Europe and North America, segregation measures were introduced to avoid patient-to-patient transmission. Presently, the prevalence of Bcc infections among CF patients worldwide is below 5% in the majority of CF centers, although exceptions are registered in some European countries. Infections by these pathogens remain problematic due to the high resistance to antimicrobials, the easy patient-to-patient transmission, and the unpredictable outcome of infections that range from asymptomatic carriage to the cepacia syndrome, a fulminating pneumonia often associated with septicemia that can lead to the decease of patients within a period of time as short as 1 week. In this chapter, we review the evolving epidemiology of Bcc infections in CF patients, the virulence traits and mechanisms used by these bacteria, and the recent developments in vaccine and vaccine components research to prevent Bcc infections

Validation of meteorological and ground-level ozone WRF-CHIMERE simulations in a mountainous grapevine growing area for phytotoxic risk assessment

Ozone is the most damaging phytotoxic air pollutant to crop yield quantity and quality. This study presents the validation of a simulation with the WRF-CHIMERE modelling system in order to assess the risk of phytotoxicity by tropospheric ozone for an important and characteristic Mediterranean crop, i.e. the grapevine. The study region was the Douro wine region in Portugal, which is characterized by a rugged relief and a Mediterranean climate. The simulation covered a reference grapevine growing season in the Northern Hemisphere (from April to September 2017), during which a particular measuring campaign was also carried out. The validation of the meteorological simulations on a daily and hourly time resolution was performed based on data from three weather stations, namely on temperature, global solar radiation, relative humidity, wind speed and direction values. The ozone phytotoxicity was assessed with data from two measuring stations. A specific grapevine growth parameter based on monitored phenological observations was introduced for ozone stomatal uptake assessment. Concerning meteorology, validation statistics were acceptable and within the range of what has been found in other regional climate modelling simulations. Ground-level ozone-based values were calculated for a better assessment of the phytotoxic risk, in particular cumulative standards for vegetation protection. Stomatal flux estimates were within the range of those measured for the local cultivars in the field campaign when there was not severe water stress limitation. Both field and statistically adjusted model values indicate that considerable areas in the Demarcated Douro Region of Portugal can exceed the critical exposure values for vegetation according to current European legislation standards. Moreover, measured and simulated results indicate an ozone impact on grapevine yield and quality in the target region because the exposure- and flux-based indices exceed the criteria based on current open-top-chamber experimental knowledge.The authors acknowledge the national funds from FCT-Science and Technology Portuguese Foundation for the doctoral grant of D. Blanco- Ward (SFRH/BD/139193/2018). Thanks are also due for the financial support to CESAM (UIDB/50017/2020+UIDP/50017/2020), to FCT/ MEC through national funds, and the co-funding by FEDER within the PT2020 Partnership Agreement and Compete 2020. The authors also wish to thank the DOUROZONE project (PTDC/AAG-MAA/3335/2014; POCI-01-0145-FEDER-016778) for financial support through Project 3599 – Promoting the Scientific Production and the Technological Development, and Thematic Networks (3599-PPCDT) – and through FEDER. Thanks are also given to SOGRAPE VINHOS S.A. for facilitating the collection of surface O3 data and sharing meteorological data at one of their vineyard fields.info:eu-repo/semantics/publishedVersio

Identification and functional analysis of novel phosphorylation sites in the RNA surveillance protein Upf1.

One third of inherited genetic diseases are caused by mRNAs harboring premature termination codons as a result of nonsense mutations. These aberrant mRNAs are degraded by the Nonsense-Mediated mRNA Decay (NMD) pathway. A central component of the NMD pathway is Upf1, an RNA-dependent ATPase and helicase. Upf1 is a known phosphorylated protein, but only portions of this large protein have been examined for phosphorylation sites and the functional relevance of its phosphorylation has not been elucidated in Saccharomyces cerevisiae. Using tandem mass spectrometry analyses, we report the identification of 11 putative phosphorylated sites in S. cerevisiae Upf1. Five of these phosphorylated residues are located within the ATPase and helicase domains and are conserved in higher eukaryotes, suggesting a biological significance for their phosphorylation. Indeed, functional analysis demonstrated that a small carboxy-terminal motif harboring at least three phosphorylated amino acids is important for three Upf1 functions: ATPase activity, NMD activity and the ability to promote translation termination efficiency. We provide evidence that two tyrosines within this phospho-motif (Y-738 and Y-742) act redundantly to promote ATP hydrolysis, NMD efficiency and translation termination fidelity

The impact of the winery's wastewater treatment system on the winery water footprint

In the Mediterranean region, water scarcity has already prompted concern in the wine sector due to the strong impact it has on vineyard productivity and wine quality. Water footprint is an indicator that takes account of all the water involved in the creation of a product and may help producers to identify hotspots, and reduce water consumption and the corresponding production costs. In recent years several studies have been reported on wine water footprint determination, but mostly focused on the viticulture phase or assuming no grey water footprint at the winery since it has a treatment system. In the framework of the WineWaterFootprint project a medium-size winery was monitored, with direct measurements, regarding determination of the blue and grey components of water footprint. The determined winery water footprint ranged from 9.6 to 12.7 L of water per wine bottle of 0.75 L, the wastewater produced being responsible for about 98%, which means that the grey component cannot be disregarded. The developed scenarios show that a potential reduction of 87% in winery water footprint can be obtained with almost no investment. The challenge of reducing the grey footprint is not in technology development, but rather in the proper maintenance and monitoring of treatment systemsinfo:eu-repo/semantics/publishedVersio

About the Yukawa model on a lattice in the quenched approximation

We study the Yukawa model on a 4-dimensional Euclidean lattice in the quenched approximation. A particular attention is given to the singularities of the Dirac operator in the phase diagram. A careful analysis of a particular limiting case shows that size effects can be huge, questioning the quenched approximation. This is confirmed by a Monte-Carlo simulation in this limit case and without the quenched approximation. We include also some results concerning the symmetries of this model.Comment: 7 figure

Health behavior and status related to mother's death in Timor-Leste

Maternal mortality (MMR) in República Democrática de Timor-Leste (RDTL) is still high among developing countries. Meanwhile, the study on the model of the relationship between medical factors, non-medical factors and factors of health care system to reduce these figures has not been done in-depth study and independent. Objective: This study aims to demonstrate health behavior and health status as a contributing factor to maternal deaths throughout Timor-Leste. Methods: The study used a case-control study design study with a retrospective approach to study the correlation dynamics between cause and effect factors. The variables collected include the characteristics, behavior and health status of the mother. Then the odds ratio is calculated to explain the strength of the causal factor influencing the effect. In this study involving 298 pregnant women living as well as the mother's family gave birth to die at 13 Municipios throughout Timor-Leste