Imaging of the gravitational lens system PG 1115+080 with the Hubble Space Telescope

This paper is the first of a series presenting observations of gravitational lenses and lens candidates, taken with the Wide Field/Planetary Camera (WFPC) of the Hubble Space Telescope (HST). We have resolved the gravitational lens system PG 1115 + 080 into four point sources and a red, extended object that is presumably the lens galaxy; we present accurate relative intensities, colors, and positions of the four images, and lower accuracy intensity and position of the lens galaxy, all at the epoch 1991.2. Comparison with earlier data shows no compelling evidence for relative intensity variations between the QSO components having so far been observed. The new data agree with earlier conclusions that the system is rather simple, and can be produced by the single observed galaxy. The absence of asymmetry in the HST images implies that the emitting region of the quasar itself has an angular radius smaller than about 10 milliarcsec (100 pc for H_0=50, q_0=0.5)

The core of the nearby S0 galaxy NGC 7457 imaged with the HST planetary camera

We have observed the nearby S0 galaxy NGC 7457 with the Planetary Camera of the Hubble Space Telescope. Spatial structure is observable at the diffraction-limited resolution of the 2.4 m HST primary despite the effects of spherical aberration. The central distribution of starlight appears consistent with a y ~ -1.0 power law for r 3 x 10^4 L_☉ pc^(-3) (V band). This is now the second densest core known after M32. From the ground, NGC 7457 resembles any number of unresolved elliptical galaxies, which suggests that compact dense cores may be common. The images of NGC 7457 demonstrate that HST can still provide unique and astrophysically interesting information on the central structure of galaxies

The Monitor project: JW 380 - a 0.26-, 0.15-M⊙, pre-main-sequence eclipsing binary in the Orion nebula cluster

We report the discovery of a low-mass (0.26 ± 0.02, 0.15 ± 0.01 M⊙) pre-main-sequence (PMS) eclipsing binary (EB) with a 5.3 d orbital period. JW 380 was detected as part of a high-cadence time-resolved photometric survey (the Monitor project) using the 2.5-m Isaac Newton Telescope and Wide Field Camera for a survey of a single field in the Orion nebula cluster (ONC) region in V and i bands. The star is assigned a 99 per cent membership probability from proper motion measurements, and radial velocity observations indicate a systemic velocity within 1σ of that of the ONC. Modelling of the combined light and radial velocity curves of the system gave stellar radii of for the primary and the secondary, with a significant third light contribution which is also visible as a third peak in the cross-correlation functions used to derive radial velocities. The masses and radii appear to be consistent with stellar models for 2-3 Myr age from several authors, within the present observational errors. These observations probe an important region of mass-radius parameter space, where there are currently only a handful of known PMS EB systems with precise measurements available in the literatur

The Monitor project: JW 380 -- a 0.26, 0.15 Msol pre main sequence eclipsing binary in the Orion Nebula Cluster

We report the discovery of a low-mass (0.26 +/- 0.02, 0.15 +/- 0.01 Msol) pre-main-sequence eclipsing binary with a 5.3 day orbital period. JW 380 was detected as part of a high-cadence time-resolved photometric survey (the Monitor project) using the 2.5m Isaac Newton Telescope and Wide Field Camera for a survey of a single field in the Orion Nebula Cluster (ONC) region in V and i bands. The star is assigned a 99 per cent membership probability from proper motion measurements, and radial velocity observations indicate a systemic velocity within 1 sigma of that of the ONC. Modelling of the combined light and radial velocity curves of the system gave stellar radii of 1.19 +0.04 -0.18 Rsol and 0.90 +0.17 -0.03 Rsol for the primary and secondary, with a significant third light contribution which is also visible as a third peak in the cross-correlation functions used to derive radial velocities. The masses and radii appear to be consistent with stellar models for 2-3 Myr age from several authors, within the present observational errors. These observations probe an important region of mass-radius parameter space, where there are currently only a handful of known pre-main-sequence eclipsing binary systems with precise measurements available in the literature.Comment: 11 pages, 9 figures, accepted for publication in MNRA

Reduction of PG:1115+080 Images

The data are three exposures in PC6 through F785LP obtained on March 3, 1991. The exposure times are 120, 400, and 400 seconds. The data are reduced with the "standard" WFPC reduction scheme: A-to-D correction, DC bias subtraction, AC bias subtraction, dark current subtraction, preflash subtraction, and flat field normalization, using the best available calibration data. The exposures are combined into a weighted average normalized to 400 seconds exposure time, so one DN (data number) is about 17.25 electrons. At this step, cosmic rays are removed by intercomparison of the three images

Planetary Camera observations of the M87 stellar cusp

Analysis of V and I band HST Planetary Camera images of the giant elliptical galaxy M87 show that its central starlight distribution is consistent with the black hole M_• = 2.6 X 10^9 M_☉ cusp model proposed for M87 by Young et al. [ApJ, 221, 721 (1978)]. A combined approach of image deconvolution and modeling is used to investigate the starlight distribution into limiting radii of ≈0".04 (3 pc at 16 Mpc). The central structure of M87 can be described by three components: a power-law starlight profile of the form µ(r)∝a:r^(-1/4) for r<3", a central nonthermal point source, and optical counterparts of the jet knots N1 and M identified by VLBI observations. M87 lacks a constant surface brightness core, and its central starlight luminosity density exceeds 10^3L_☉ pc^(-3) (I band) for r< 10 pc. The profile strongly resembles a stellar cusp associated with a massive black hole. A review of existing velocity dispersion observations suggests that the Young et al. black hole mass can be accommodated to the observations with minor adjustments of dynamical models. The central luminosity spike itself remains unresolved at HST resolution, with r_c < 1 pc. The spike has optical spectral index ɑ= -0.46 ± 0.20 and is at least as blue if not bluer than the rest of the M87 jet. The total nonthermal flux in the inner 1" of M87 agrees well with the central radio flux and the radio-optical spectral index of the rest of the jet. It is also consistent with the spectral-line dilution seen by Dressler & Richstone [ApJ, 348, 120 ( 1990)]; we thus argue that the spike is completely nonthermal

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease

Neurofilament light chain (NfL) is a promising fluid biomarker of disease progression for various cerebral proteopathies. Here we leverage the unique characteristics of the Dominantly Inherited Alzheimer Network and ultrasensitive immunoassay technology to demonstrate that NfL levels in the cerebrospinal fluid (n = 187) and serum (n = 405) are correlated with one another and are elevated at the presymptomatic stages of familial Alzheimer's disease. Longitudinal, within-person analysis of serum NfL dynamics (n = 196) confirmed this elevation and further revealed that the rate of change of serum NfL could discriminate mutation carriers from non-mutation carriers almost a decade earlier than cross-sectional absolute NfL levels (that is, 16.2 versus 6.8 years before the estimated symptom onset). Serum NfL rate of change peaked in participants converting from the presymptomatic to the symptomatic stage and was associated with cortical thinning assessed by magnetic resonance imaging, but less so with amyloid-β deposition or glucose metabolism (assessed by positron emission tomography). Serum NfL was predictive for both the rate of cortical thinning and cognitive changes assessed by the Mini-Mental State Examination and Logical Memory test. Thus, NfL dynamics in serum predict disease progression and brain neurodegeneration at the early presymptomatic stages of familial Alzheimer's disease, which supports its potential utility as a clinically useful biomarker