517 research outputs found

    Main and Minor Types of Collagens in the Articular Cartilage: The Role of Collagens in Repair Tissue Evaluation in Chondral Defects

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    Several collagen subtypes have been identified in hyaline articular cartilage. The main and most abundant collagens are type II, IX and XI collagens. The minor and less abundant collagens are type III, IV, V, VI, X, XII, XIV, XVI, XXII, and XXVII collagens. All these collagens have been found to play a key role in healthy cartilage, regardless of whether they are more or less abundant. Additionally, an exhaustive evaluation of collagen fibrils in a repaired cartilage tissue after a chondral lesion is necessary to determine the quality of the repaired tissue and even whether or not this repaired tissue is considered hyaline cartilage. Therefore, this review aims to describe in depth all the collagen types found in the normal articular cartilage structure, and based on this, establish the parameters that allow one to consider a repaired cartilage tissue as a hyaline cartilage

    Carbapenemase-producing enterobacteriaceae in Spain in 2012

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    We report the epidemiological impact of carbapenemase-producing Enterobacteriaceae (CPE) in Spain in 2012. Of the 237 carbapenemases detected, 163 were from the OXA-48 group, 60 were from VIM-1, 8 were from KPC-2, 5 were from IMP, and 1 was from NDM-1. Interhospital spread of carbapenemase-producing Klebsiella pneumoniae was due to a limited number of multilocus sequence types (MLST) and carbapenemase types, including ST15-VIM-1, ST11-OXA-48, ST405-OXA-48, ST101-KPC-2, and ST11-VIM-1. The number of CPE cases in Spain has increased sharply in recent years, due mainly to the emergence of OXA-48.This study was supported by the Antibiotic Resistance Surveillance Program of the Spanish Centro Nacional de Microbiología of the Instituto de Salud Carlos III. Verónica Bautista was supported by the Ministerio de Economía y Competitividad, Instituto de Salud Carlos III, cofinanced by the European Development Regional Fund “A way to achieve Europe” ERDF, Spanish Network for the Research in Infectious Diseases (REIPI RD12/0015).S

    Acoustic conditioning of the neonatal incubator compartment: Improvement proposal

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    The objective of this work focuses on the study of the main sources of noise associated with incubators and the acoustic effects that derive from them. The method that has been established is based on tests carried out under different operating conditions of the incubators. Noise levels are analyzed under different boundary conditions (Neonatal ICU and "Controlled environment rooms"). Under normal operating conditions, the levels inside the incubator are around 56 dB (A), values that exceed the maximum limits recommended by the American Academy of Pediatrics. The scope of this study is to evaluate the existing noise levels in the incubator and analyze possible design improvements. The study was carried out in the hospitals of Cadiz, Huelva, and Malaga

    El prestigio profesional y social: determinante de la decisión vocacional

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    ABSTRACTThe development of career maturity is a key issue in the lives of people. The decisions made by young people in this area have important personal, social and economic implications. Variable professional prestige has been considered to be traditionally one more between others of the explanatory variables of the vocational decision. The present study tries to demonstrate, that at present, variable professional prestige is more than an explanatory or determining variable, is a determinant of the vocational decision. This will allow the counsellors and educational psychologists of the Elementary and Secondary centers to base their guidance not only on the interests, skills and personality, more traditional variables considered in career guidance counselling to students, but bear in mind also in the advices the professional prestige that every student grants to the different professions. There has been selected a sample of 246 subjects selected from different degrees of the University of Almeria. As a measuring instrument were used professional prestige scales: PRESCA 1 and 2. In conclusion, the most important, is that students from each of the qualifications considered to yours like more social prestige, other conclusions are: that the most prestigious degrees are technical, experimental careers and field related health, which are valued to a lesser extent the degrees related to education, there are significant differences in perceiving the prestige of qualifications depending on sex.RESUMENEl desarrollo de la madurez de carrera es un aspecto básico en la vida de las personas. Las decisiones que tomen los jóvenes en este ámbito tienen importantes implicaciones personales, sociales y económicas. La variable prestigio profesional ha sido considerada tradicionalmente como una más entre otras de las variables explicativas de la decisión vocacional. El presente estudio pretende demostrar que en la actualidad la variable prestigio profesional es más que una variable explicativa o condicionante, es un determinante de la decisión vocacional. Esto permitirá a los orientadores/as y psicopedagogos/as de los centros de Primaria y Secundaria basar sus orientaciones no sólo en los intereses, aptitudes y personalidad, variables tradicionales más tenidas en cuenta en la orientación vocacional para hacer asesoramiento a los estudiantes, sino tener también en cuenta en los asesoramientos el prestigio profesional que cada estudiante otorga a las diferentes profesiones. Se ha seleccionado una muestra de 246 sujetos seleccionados de diferentes titulaciones de la Universidad de Almería. Como instrumento de medida, se han utilizado las escalas de prestigio profesional: PRESCA 1 y 2. Como conclusiones, la más relevante, es que los estudiantes de cada una de las titulaciones consideran a la suya como la de mayor prestigio social, otras conclusiones son: que las titulaciones más prestigiosas, son las carreras técnicas, experimentales y las relacionadas con el ámbito de la salud, que se valoran en menor medida las titulaciones vinculadas con la educación, que existen diferencias significativas al percibir el prestigio de las titulaciones en función del sexo.ABSTRACTThe development of career maturity is a key issue in the lives of people. The decisions made by young people in this area have important personal, social and economic implications. Variable professional prestige has been considered to be traditionally one more between others of the explanatory variables of the vocational decision. The present study tries to demonstrate, that at present, variable professional prestige is more than an explanatory or determining variable, is a determinant of the vocational decision. This will allow the counsellors and educational psychologists of the Elementary and Secondary centers to base their guidance not only on the interests, skills and personality, more traditional variables considered in career guidance counselling to students, but bear in mind also in the advices the professional prestige that every student grants to the different professions. There has been selected a sample of 246 subjects selected from different degrees of the University of Almeria. As a measuring instrument were used professional prestige scales: PRESCA 1 and 2. In conclusion, the most important, is that students from each of the qualifications considered to yours like more social prestige, other conclusions are: that the most prestigious degrees are technical, experimental careers and field related health, which are valued to a lesser extent the degrees related to education, there are significant differences in perceiving the prestige of qualifications depending on sex.

    Occupational factors associated with health-related quality of life in nursing professionals: a multi-centre study

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    Background: Nursing professionals are exposed to stressful situations arising from the work context that may affect health-related quality of life (HRQoL). The objective of this study was to analyse the relationship between sociodemographic and work-related variables regarding HRQoL in nursing professionals. Methods: A multi-centre, cross-sectional descriptive design was used. The participants consisted 1521 nurses working in healthcare centres, in both primary care and hospital care, in the eight provinces of the Andalusian Public Health System (APHS), Spain. Sociodemographic and work-related variables were analysed: Compassion fatigue, compassion satisfaction and burnout were measured using the professional quality of life questionnaire (ProQOL), and HRQoL was measured using the SF-12 health questionnaire. Results: Compassion fatigue, burnou, and, to a lesser extent, compassion satisfaction significantly influence the physical and mental components of HRQoL. The simple regression analysis showed that burnout and compassion fatigue were significantly associated with the mental component of HRQoL. Gender influenced the mental component of HRQoL. The rest of the sociodemographic and work-related variables were not significantly related to HRQoL. Conclusion: Work-related stress and repeated contact with situations of suffering influence HRQoL. Health systems must implement programmes to increase the emotional well-being of workers

    «Oberexia»: The desire to be fat(ter) in adults with excess weight

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    Introduction: Despite of being scarce, evidence is growing on the existence of a group of overweight and obese individuals who do not consider their weight a risk factor for disease and who associate their weight and body with health, vigor, beauty and well-being. Consequently, they manifest a desire to maintain or even increase their weight. We propose an attempt of nomenclature, Oberexia, for this new social reality, and we describe its main characteristics and present empirical observational findings supporting the existence of this condition. Objective: The aim of this study was to explore the prevalence and characteristics of Oberexia in a national sample of Spanish 16 to 60-years-old adults. Methodology: Perceptions of body weight/size/shape and composition, and body satisfaction were assessed in overweight and obese adults through silhouettes, questions and discrepancies. Results: One in ten of the participants self-perceived their body as normal in weight or size. A total of 6.5% wanted to have overweight or obese bodies. A case-to-case analysis revealed that 4.2% of the participants wanted to maintain their appearance, and 1.8% wanted a body with greater weight. All these findings are related to fat mass instead of muscle mass. Conclusions: Our results support the existence of a subgroup of overweight and obese individuals who differ from the traditional subgroup of individuals with excess weight who are dissatisfied with their body. We encourage to explore the outcomes on health and the possible clinical implications of this condition.Introducción: Aunque escasa, existe evidencia creciente sobre la existencia de un grupo de personas con sobrepeso y obesidad que no consideran su exceso de peso un factor de riesgo para la enfermedad y asocian su peso y su cuerpo con salud, vigor, belleza y bienestar. Como consecuencia, manifiestan el deseo mantener o incluso incrementar su peso. Realizamos una propuesta de nomenclatura para esta realidad social, Oberexia, describimos sus principales características y presentamos resultados empíricos observacionales que apoyan la existencia de esta condición. Objetivo: Nuestro objetivo fue explorar la prevalencia y características de la Oberexia en una muestra nacional de adultos españoles de 16 a 60 años. Metodología: Las percepciones de peso/tamaño/forma y composición corporal de personas con sobrepeso y obesidad y su satisfacción corporal fueron evaluadas utilizando siluetas, preguntas y discrepancias. Resultados: Uno de cada diez participantes percibió su cuerpo como normal en términos de peso y tamaño. Un 6.5% de los participantes con exceso de peso quería tener cuerpos con sobrepeso u obesidad. Un análisis caso-a-caso reveló que el 4.2% de los participantes deseaba mantener su apariencia, y el 1.8% deseaba aumentar de peso. Un 3% de los participantes podrían ser casos de Oberexia. Estos hallazgos se refieren a masa grasa y no a masa muscular. Conclusiones: Nuestros resultados apoyan la existencia de un subgrupo de personas con exceso de peso que difieren del tradicional subgrupo de individuos obesos que se encuentran insatisfechos con su cuerpo. Es momento de explorar las consecuencias para la salud de la Oberexia y las posibles implicaciones clínicas de esta condición.Introdução: Apesar de escassas, crescem as evidências sobre a existência de um grupo de pessoas com sobrepeso e obesidade que não consideram o excesso de peso um fator de risco para a doença e associam seu peso e corpo com saúde, vigor, beleza e bem-estar. Consequentemente, eles manifestam o desejo de manter ou mesmo aumentar seu peso. Fizemos uma proposta de nomenclatura para essa realidade social, Oberexia, descrevemos suas principais características e apresentamos resultados empíricos observacionais que sustentam a existência dessa condição. Objetivo: O objetivo deste estudo foi explorar a prevalência e as características de Oberexia em uma amostra nacional de adultos espanhóis de 16 a 60 anos. Metodologia: As percepções de peso/tamanho/forma e composição corporal de pessoas com sobrepeso e obesidade e sua satisfação corporal foram avaliadas por meio de silhuetas, perguntas e discrepâncias. Resultados: Um em cada dez participantes percebeu seu corpo como normal em termos de peso ou tamanho. Um 6.5% dos participantes com excesso de peso desejava ter corpos com sobrepeso ou obesidade. Uma análise caso-a-caso revelou que 4.2% dos participantes queriam manter a aparência e 1.8% desejavam ganhar peso. Un 3% dos participantes poderia ser casos de Oberexia. Todos esses achados referem-se à massa gorda e não à massa muscular. Conclusões: Nossos resultados confirmam a existência de um subgrupo de indivíduos com sobrepeso e obesidade que diferem do subgrupo tradicional de indivíduos com excesso de peso insatisfeitos com seu corpo. É momento de explorar as consequências para a saúde de a Oberexia e as possíveis implicações clínicas dessa condição

    Preliminary Results on the Preinduction Cervix Status by Shear Wave Elastography

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    The mechanical status of the cervix is a key physiological element during pregnancy. By considering a successful induction when the active phase of labor is achieved, mapping the mechanical properties of the cervix could have predictive potential for the management of induction protocols. In this sense, we performed a preliminary assessment of the diagnostic value of using shear wave elastography before labor induction in 54 women, considering the pregnancy outcome and Cesarean indications. Three anatomical cervix regions and standard methods, such as cervical length and Bishop score, were compared. To study the discriminatory power of each diagnostic method, a receiver operating characteristic curve was generated. Differences were observed using the external os region and cervical length in the failure to enter the active phase group compared to the vaginal delivery group (p < 0.05). The area under the ROC curve resulted in 68.9%, 65.2% and 67.2% for external os, internal os and cervix box using elastography, respectively, compared to 69.5% for cervical length and 62.2% for Bishop score. External os elastography values have shown promise in predicting induction success. This a priori information could be used to prepare a study with a larger sample size, which would reduce the effect of any bias selection and increase the predictive power of elastography compared to other classical techniques.Ministerio de Educacion, Cultura y Deporte grant DPI2017-83859-R DPI2014-51870-R UNGR15-CE-3664 EQC2018-004508-PSpanish Government DTS15/00093 PI16/00339Instituto de Salud Carlos IIISpanish GovernmentEuropean Commission PID2020-115372RB-I00 PYC20 RE 072 UGRInstituto de Salud Carlos III y Fondos FederJunta de Andalucia PI-0107-2017 PIN-0030-2017 IE2017-5537 B-TEP-026-UGR18 P18-RT-1653MCIN/AEI (European Social Fund "Investing in your future") PRE2018-086085European Commission P18-RT-1653 SOMM17/6109/UG

    Estimating Stand and Fire-Related Surface and Canopy Fuel Variables in Pine Stands Using Low-Density Airborne and Single-Scan Terrestrial Laser Scanning Data

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    [EN] In this study, we used data from a thinning trial conducted on 34 different sites and 102 sample plots established in pure and even-aged Pinus radiata and Pinus pinaster stands, to test the potential use of low-density airborne laser scanning (ALS) metrics and terrestrial laser scanning (TLS) metrics to provide accurate estimates of variables related to surface and canopy fires. An exhaustive field inventory was carried out in each plot to estimate the main stand variables and the main variables related to fire hazard: surface fuel loads by layers, fuel strata gap, surface fuel height, stand mean height, canopy base height, canopy fuel load and canopy bulk density. In addition, the point clouds from low-density ALS and single-scan TLS of each sample plot were used to calculate metrics related to the vertical and horizontal distribution of forest fuels. The comparative performance of the following three non-parametric machine learning techniques used to estimate the main stand-and fire-related variables from those metrics was evaluated: (i) multivariate adaptive regression splines (MARS), (ii) support vector machine (SVM), and (iii) random forest (RF). The selection of the best modeling approach was based on a comparison of the root mean square error (RMSE), obtained by optimizing the parameters of each technique and performing crossvalidation. Overall, the best results were obtained with the MARS techniques for data from both sensors. The TLS data provided the best results for variables associated with the internal characteristics of canopy structure and understory fuel but were less reliable for estimating variables associated with the upper canopy, due to occlusion by mid-canopy foliage. The combination of ALS and TLS metrics improved the accuracy of estimates for all variables analyzed, except the height and the biomass of the understory shrubs. The variability demonstrated by the combined use of both types of metrics ranged from 43.11% for the biomass of duff litter layers to 94.25% for dominant height. The results suggest that the combination of machine learning techniques and metrics derived from low-density ALS data, drawn from a single-scan TLS or a combination of both metrics, may represent a promising alternative to traditional field inventories for obtaining valuable information about surface and canopy fuel variables at large scalesSIThis research was funded by the projects GEPRIF (RTA2014-00011-C06-04) and VIS4FIRE (RTA2017-00042-C05-05) of the Spanish Ministry of Economy, Industry, and Competitiveness and a pre-doctoral grant of the first author funded by the “Consejería de Educación, Universidad y Formación Profesional” and the “Consejería de Economía, Empleo e Industria” of the Galician Government and the EU operational program “FSE Galicia 2014–2020”

    Tratamiento quirúrgico de la miocardiopatía hipertrófica obstructiva mediante la técnica de Konno modificada

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    ResumenObjetivoMostrar la eficacia, seguridad y reproducibilidad de la técnica de Konno modificada en la resolución de la miocardiopatía hipertrófica obstructiva.MétodosCuatro casos de miocardiopatía hipertrófica obstructiva, con edades de 8–59 años, 3 mujeres y 1 varón, clínica de angina, disnea y presíncopes. Gradiente máximo de 65–120 mmHg. Todos presentaban movimiento sistólico anterior de la válvula mitral e insuficiencia mitral, y fueron intervenidos con técnica de Konno modificada.ResultadosTodos sobrevivieron. El gradiente preoperatorio descendió un 91%. Tres casos quedaron con insuficiencia mitral ligera, todos pasaron a grado funcional I. Única complicación: necesidad de marcapasos definitivo en un caso. Seguimiento medio de 54 meses.ConclusionesEsta técnica cambia la resección septal de Morrow por la ampliación del tracto de salida del ventrículo izquierdo. Se ha mostrado eficaz y segura, con resultados estables.AbstractBackgroundThe efficacy, safety and feasibility of the modified Konno procedure for the surgical correction of hypertrophic obstructive cardiomyopathy (HOCM) are demonstrated.MethodsFour patients underwent a modified Konno procedure. The ages ranged from 8 to 59 years. There were three females and one male. Symptoms referred to were angina, dyspnea and presyncope. The echocardiography study revealed a maximum gradient between 65–120mm Hg. Systolic anterior motion of mitral valve and mitral regurgitation was present in all cases.ResultsThere were no in-hospital deaths. The gradients decreased by 91%. Mild postoperative mitral regurgitation was present in three patients. One permanent pacemaker was implanted. Mean follow up was 54 months.ConclusionsThis procedure is an alternative to the Morrows septal myectomy for the correction of HOCM, allowing a greater enlargement of the left ventricular outflow tract. It can be performed with good early and mid-term results proving to be safe and feasible

    Determinantes psicosociales y deportivos de la intención de continuar la participación en la práctica deportiva y la competición en atletas con discapacidad

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    Las experiencias de flow, la competencia deportiva percibida y la pasión han sido relacionadas con la adherencia a la práctica deportiva y el rendimiento en deportistas sin discapacidad, pero existe escasa evidencia de ello en el deporte adaptado. En este estudio correlacional, exploramos el flow, la competencia percibida y la pasión armoniosa y obsesiva en deportistas con diversidad funcional de diferentes modalidades y niveles competitivos, y su influencia sobre la intención de práctica y competición futura. Se realizaron análisis de correlaciones de orden cero y análisis multivariados de regresión lineal. Los participantes informaron tener niveles moderadamente altos de flow, particularmente en la mejor competición, así como elevada competencia deportiva percibida y pasión por el deporte, particularmente pasión armoniosa. Entre las variables psicosociales y deportivas consideradas, la intención de práctica futura fue predicha por la competencia percibida, mientras que la intención de competición futura fue predicha por la pasión obsesiva y el nivel de competición. Las intervenciones dirigidas a la promoción de la participación deportiva y el incremento del rendimiento en atletas con discapacidad deben considerar estos poderosos recursos psicológicos.Esta investigación fue &nanciada en parte con la ayuda del grupo de investigación «Psicología de la Salud/Medicina Conductual» (CTS-0267) concedida por la Consejería de Economía y Conocimiento de la Junta de Andalucía (España)
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