22 research outputs found
Guidelines for Planning Facilities for the Adult Learner
The purpose of this study was to survey selected existing facilities and to develop guidelines for planning facilities for the adult learner. The following subproblems were identified in order to adequately treat the problem: (1) To describe selected facilities for the adult learner; (2) To identify those elements considered essential, highly desirable, and significant in planning a facility for the adult learner. Four research questions were considered to be relevant to this study: (1) What were the most prevalent needs of the adult learner? (2) What facilities for the adult learner are in existence now? (3) What recommendations are given for planning a facility for the adult learner? (4) Will the total responses obtained by on-site visitations be consistent with the total responses of the mailed questionnaire? Through the review of literature, a list of thirty selected existing facilities was compiled. The participants in the study were limited to twelve randomly selected facilities for the adult learner. In addition, three selected facilities were visited. A questionnaire was developed and field tested to assess those guideline elements considered essential, highly desirable, and significant in planning facilities for the adult learner. A total of thirteen sources responded to the questionnaire. Three directors of facilities where on-site visitations were conducted participated in the study. Ten directors of facilities for the adult learner in various geographical locations in the United States participated in the study. From the analysis of the data from the questionnaire responses, ninety-six elements were found to be essential, highly desirable, or significant. These elements were arrayed from essential through significant and presented as guidelines for developing facilities for the adult learner. Recommendations based on the findings were given
Guidelines for Planning Facilities for the Adult Learner
The purpose of this study was to survey selected existing facilities and to develop guidelines for planning facilities for the adult learner. The following subproblems were identified in order to adequately treat the problem: (1) To describe selected facilities for the adult learner; (2) To identify those elements considered essential, highly desirable, and significant in planning a facility for the adult learner. Four research questions were considered to be relevant to this study: (1) What were the most prevalent needs of the adult learner? (2) What facilities for the adult learner are in existence now? (3) What recommendations are given for planning a facility for the adult learner? (4) Will the total responses obtained by on-site visitations be consistent with the total responses of the mailed questionnaire? Through the review of literature, a list of thirty selected existing facilities was compiled. The participants in the study were limited to twelve randomly selected facilities for the adult learner. In addition, three selected facilities were visited. A questionnaire was developed and field tested to assess those guideline elements considered essential, highly desirable, and significant in planning facilities for the adult learner. A total of thirteen sources responded to the questionnaire. Three directors of facilities where on-site visitations were conducted participated in the study. Ten directors of facilities for the adult learner in various geographical locations in the United States participated in the study. From the analysis of the data from the questionnaire responses, ninety-six elements were found to be essential, highly desirable, or significant. These elements were arrayed from essential through significant and presented as guidelines for developing facilities for the adult learner. Recommendations based on the findings were given
Harmonizing model organism data in the Alliance of Genome Resources.
The Alliance of Genome Resources (the Alliance) is a combined effort of 7 knowledgebase projects: Saccharomyces Genome Database, WormBase, FlyBase, Mouse Genome Database, the Zebrafish Information Network, Rat Genome Database, and the Gene Ontology Resource. The Alliance seeks to provide several benefits: better service to the various communities served by these projects; a harmonized view of data for all biomedical researchers, bioinformaticians, clinicians, and students; and a more sustainable infrastructure. The Alliance has harmonized cross-organism data to provide useful comparative views of gene function, gene expression, and human disease relevance. The basis of the comparative views is shared calls of orthology relationships and the use of common ontologies. The key types of data are alleles and variants, gene function based on gene ontology annotations, phenotypes, association to human disease, gene expression, protein-protein and genetic interactions, and participation in pathways. The information is presented on uniform gene pages that allow facile summarization of information about each gene in each of the 7 organisms covered (budding yeast, roundworm Caenorhabditis elegans, fruit fly, house mouse, zebrafish, brown rat, and human). The harmonized knowledge is freely available on the alliancegenome.org portal, as downloadable files, and by APIs. We expect other existing and emerging knowledge bases to join in the effort to provide the union of useful data and features that each knowledge base currently provides
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts
How Do You Say Computer in Hawaiiaiian?
If there was one watershed moment for the dying Hawaiian language, it must have come in 1983, when a study showed that only 32 students under
18 (most of them concentrated in remote hamlets of Kaua'i and Ni'ihau) were able to speak Hawaiian. Immediately after the study, a dedicated group of professors and activists - many of them now at the University of Hawai'i in Hilo - gathered in Honolulu to start plotting the great Hawaiian-language comeback. Step One: repeal the century-old law prohibiting the teaching of Hawaiian in public schools. Step Two: establish a system of public schools with Hawaiian-language immersion programs. Once the schools started opening, it came time to hoist the Hawaiian language into the techno age - hook, line, and SLIP connection. That's when NeSmith joined forces with Keiki Kawai'ae'a and Keola Donaghy. In computer networks the three found a new medium that used the oral and the textual as its currency, a medium perhaps better suited to an oral tradition than the book ever was
Collaborative Concession in Food Movement Networks: The Uneven Relations of Resource Mobilization
Understanding partnerships for sustainable development analytically: the ladder of partnership activity as a methodological tool
This paper studies the development of partnerships for sustainable development as a
process in which actors from various sectors of society (state, market and civil) restructure
and build new social relationships to create a more sustainable management practice. In
the relevent literature we recognize three perspectives on this issue. From the fi rst, partnerships
are studied as single collaborative arrangements. From the second perspective,
attention is turned to the external effects of partnerships. Partnership arrangements are
seen as tools for deliberate societal change. The third perspective takes a broader view on
the governance system. Attention is focused on the changes that partnerships make in the
confi guration of public decision-making structures. These perspectives will be connected
in a Ladder of Partnership Activity, a conceptual device that allows us to better understand
and analyse partnerships. The Ladder consists of fi ve core levels, set in a time frame. Each
level is represented by a core activity. The Ladder is further encapsulated in three dimensions.
Taking examples from recent empirical studies, the paper discusses each of the
levels and their relationships. The fi nal section refl ects on the applicability of the Ladder
concept and its strengths and weaknesses. Copyright © 2010 John Wiley & Sons, Ltd and
ERP Environment