4,620 research outputs found

    Carbapenems, Linezolid, Teicoplanin utilization evaluation in a large teaching based hospital (Shahid Rajaie Heart Center, Tehran): A quality improvement study

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    The Aim of this study is to access the number of inappropriate usages of post CABG antibiotics such as, Carbapenems, Teicoplanin and Linezolid in Shahid Rajaie Hospital and to apply antibiotic practice guidelines and strategies to reduce inadequate treatment while determining their impact on patient outcomes. This retrospective study was performed at special wards of Shahid Rajaie Hospital. The program was conducted since March to August 2015. All of the patients which were on Imipenem, Meropenem, Linezolide or Teicoplanin as an empiric treatment or based on culture results were considered in the study. The results of this study indicated that among 136 in-patients who had taken at least one of these antibiotics including Imipenem, Meropenem, Linezolide or Teicoplanin, antimicrobial prescription assumed inappropriate for 63 patients (46.32), The most common reason was incorrect dosage (16.39)and the least one was not being drug of choice(2.4).this inappropriateness was occurred mostly in diagnosis of respiratory infection, skin infection and sepsis. The results of this study demonstrates the need for revision in program of prescribing antibiotics in the direction of using antibiotic practice guidelines especially regarding usage of Teicoplanin and Meropenem in specific complication such as respiratory infection and skin infection. � 2016, Oriental Scientific Publishing Company. All rights reserved

    Albumin utilization review to evaluate the efficacy and cost, perform as a qualitative study in special wards in Shaheed Rajaei cardiovascular, medical &research center

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    Drug utilization studies may be one of the major design of optimizing the costeffectiveness of treatment regimens and drugs that used to compare the costs and effects of alternative therapies. Human albumin (HA) is widely used for hypoalbuminemia and other diseases from deficiency of blood and liver factors. HA cost in the clinical setting is still controversial And Since use of albumin an established second line therapy process which is to be used in supportive drug for patients .on this study Trying to find first albumin protocol therapy cost was evaluated Then appropriate practice to be Alternate. A prospective, cross-sectional research was performed in "Shaheed Rajaei" Cardiovascular, Medical and Research Center during a 6-month continuous interval, in which, 300 patients have been evaluated .The study included patients who on a daily basis take albumin from the central pharmacy of Shaheed Rajaei hospital attaints time of receipt drug until discharge from hospital or termination of treatment were studied continuously. Demographic data including dose, intervals and durations have been registered, and then compared with international guidelines such as Data analyses have been done by SPSS 16 software. The results of this study indicated that among 300 in-patients who had prescribed albumin prescription assumed inappropriate for 281 patients (93.7), The most common reason was incorrect indication of prescription without checking serum albumin level (56.39) .base on this study the most reasons of albumin use were ascites and edema (57.9),during the course of CABG(27.5),hypoalbuminemia and hypoproteinemia(33.3),acute nephritis(17.6),hemodialysis(19.6). also rate of infusion error was (16.5 )and error related to dosages of order was ( 23.8 ).according to guidelines dosage of adminstration must be base on weight and serum albumin level that not be considred in intensive wards. According to data from this study suggests that You can see the protocol therapy based on the patient's needs Albumin consumption to reduce the cost of treatment and The lack of effectiveness of the drug, especially compared to other alternative medicines reduced

    Exploration of the ISO9000 Quality Management System Introduced to Local Government: The Analysis Based on Five Main Standards

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    随着现代经济的蓬勃发展,国际贸易日益繁荣,科学技术日新月异,政府职能覆盖范围也日益扩大。政府作为公共权力行使者,在整个社会中扮演着非常重要的角色。政府的工作质量关系到政府自身的发展、人们的生活和社会的稳定。地方政府导入ISO9000质量管理体系不仅提高了政府的办事效率,增强了公民满意度,而且为建设服务型政府、全面质量管理型政府、廉洁透明型政府和节约型政府提供了有效途径。在加入了WTO后,如何让我国更好更快地融入了世界经济一体化的进程中,这就对中国政府质量提出了更高的要求。 本文主要采用文献研究和文本分析的方法,通过文献研究法检索和通读国内外有关质量管理相关理论的教材、专著、论文等各种研究成果...With the vigorous development of the modern economy, international trade is growing prosperity and abundance. Science and technology are developing rapidly, The coverage of the government functions is also increasing. The government plays an important role in entire society as a public authority executor. The quality of the governments work relates to government's own development, people's lives a...学位:管理学硕士院系专业:公共事务学院公共管理系_行政管理学号:1392009115045

    Measurement of the Branching Fraction for B- --> D0 K*-

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    We present a measurement of the branching fraction for the decay B- --> D0 K*- using a sample of approximately 86 million BBbar pairs collected by the BaBar detector from e+e- collisions near the Y(4S) resonance. The D0 is detected through its decays to K- pi+, K- pi+ pi0 and K- pi+ pi- pi+, and the K*- through its decay to K0S pi-. We measure the branching fraction to be B.F.(B- --> D0 K*-)= (6.3 +/- 0.7(stat.) +/- 0.5(syst.)) x 10^{-4}.Comment: 7 pages, 1 postscript figure, submitted to Phys. Rev. D (Rapid Communications

    Evidence for the Rare Decay B -> K*ll and Measurement of the B -> Kll Branching Fraction

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    We present evidence for the flavor-changing neutral current decay BK+B\to K^*\ell^+\ell^- and a measurement of the branching fraction for the related process BK+B\to K\ell^+\ell^-, where +\ell^+\ell^- is either an e+ee^+e^- or μ+μ\mu^+\mu^- pair. These decays are highly suppressed in the Standard Model, and they are sensitive to contributions from new particles in the intermediate state. The data sample comprises 123×106123\times 10^6 Υ(4S)BBˉ\Upsilon(4S)\to B\bar{B} decays collected with the Babar detector at the PEP-II e+ee^+e^- storage ring. Averaging over K()K^{(*)} isospin and lepton flavor, we obtain the branching fractions B(BK+)=(0.650.13+0.14±0.04)×106{\mathcal B}(B\to K\ell^+\ell^-)=(0.65^{+0.14}_{-0.13}\pm 0.04)\times 10^{-6} and B(BK+)=(0.880.29+0.33±0.10)×106{\mathcal B}(B\to K^*\ell^+\ell^-)=(0.88^{+0.33}_{-0.29}\pm 0.10)\times 10^{-6}, where the uncertainties are statistical and systematic, respectively. The significance of the BK+B\to K\ell^+\ell^- signal is over 8σ8\sigma, while for BK+B\to K^*\ell^+\ell^- it is 3.3σ3.3\sigma.Comment: 7 pages, 2 postscript figues, submitted to Phys. Rev. Let

    Study of e+e- --> pi+ pi- pi0 process using initial state radiation with BABAR

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    The process e+e- --> pi+ pi- pi0 gamma has been studied at a center-of-mass energy near the Y(4S) resonance using a 89.3 fb-1 data sample collected with the BaBar detector at the PEP-II collider. From the measured 3pi mass spectrum we have obtained the products of branching fractions for the omega and phi mesons, B(omega --> e+e-)B(omega --> 3pi)=(6.70 +/- 0.06 +/- 0.27)10-5 and B(phi --> e+e-)B(phi --> 3pi)=(4.30 +/- 0.08 +/- 0.21)10-5, and evaluated the e+e- --> pi+ pi- pi0 cross section for the e+e- center-of-mass energy range 1.05 to 3.00 GeV. About 900 e+e- --> J/psi gamma --> pi+ pi- pi0 gamma events have been selected and the branching fraction B(J/psi --> pi+ pi- pi0)=(2.18 +/- 0.19)% has been measured.Comment: 21 pages, 37 postscript figues, submitted to Phys. Rev.

    Measurement of Branching Fraction and Dalitz Distribution for B0->D(*)+/- K0 pi-/+ Decays

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    We present measurements of the branching fractions for the three-body decays B0 -> D(*)-/+ K0 pi^+/-andtheirresonantsubmodes and their resonant submodes B0 -> D(*)-/+ K*+/- using a sample of approximately 88 million BBbar pairs collected by the BABAR detector at the PEP-II asymmetric energy storage ring. We measure: B(B0->D-/+ K0 pi+/-)=(4.9 +/- 0.7(stat) +/- 0.5 (syst)) 10^{-4} B(B0->D*-/+ K0 pi+/-)=(3.0 +/- 0.7(stat) +/- 0.3 (syst)) 10^{-4} B(B0->D-/+ K*+/-)=(4.6 +/- 0.6(stat) +/- 0.5 (syst)) 10^{-4} B(B0->D*-/+ K*+/-)=(3.2 +/- 0.6(stat) +/- 0.3 (syst)) 10^{-4} From these measurements we determine the fractions of resonant events to be : f(B0-> D-/+ K*+/-) = 0.63 +/- 0.08(stat) +/- 0.04(syst) f(B0-> D*-/+ K*+/-) = 0.72 +/- 0.14(stat) +/- 0.05(syst)Comment: 7 pages, 3 figures submitted to Phys. Rev. Let

    Measurement of the B+ --> p pbar K+ Branching Fraction and Study of the Decay Dynamics

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    With a sample of 232x10^6 Upsilon(4S) --> BBbar events collected with the BaBar detector, we study the decay B+ --> p pbar K+ excluding charmonium decays to ppbar. We measure a branching fraction Br(B+ --> p pbar K+)=(6.7+/-0.5+/-0.4)x10^{-6}. An enhancement at low ppbar mass is observed and the Dalitz plot asymmetry suggests dominance of the penguin amplitude in this B decay. We search for a pentaquark candidate Theta*++ decaying into pK+ in the mass range 1.43 to 2.00 GeV/c2 and set limits on Br(B+ --> Theta*++pbar)xBr(Theta*++ --> pK+) at the 10^{-7} level.Comment: 8 pages, 7 postscript figures, submitted to Phys. Rev. D (Rapid Communications

    Measurement of the quasi-elastic axial vector mass in neutrino-oxygen interactions

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    The weak nucleon axial-vector form factor for quasi-elastic interactions is determined using neutrino interaction data from the K2K Scintillating Fiber detector in the neutrino beam at KEK. More than 12,000 events are analyzed, of which half are charged-current quasi-elastic interactions nu-mu n to mu- p occurring primarily in oxygen nuclei. We use a relativistic Fermi gas model for oxygen and assume the form factor is approximately a dipole with one parameter, the axial vector mass M_A, and fit to the shape of the distribution of the square of the momentum transfer from the nucleon to the nucleus. Our best fit result for M_A = 1.20 \pm 0.12 GeV. Furthermore, this analysis includes updated vector form factors from recent electron scattering experiments and a discussion of the effects of the nucleon momentum on the shape of the fitted distributions.Comment: 14 pages, 10 figures, 6 table

    Search for the W-exchange decays B0 --> Ds(*)- Ds(*)+

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    We report a search for the decays B0DsDs+B^{0} \to D_{s}^{-} D_{s}^{+}, B0DsDs+B^{0} \to D_{s}^{*-} D_{s}^{+}, B0DsDs+B^{0} \to D_{s}^{*-} D_{s}^{*+} in a sample of 232 million Υ(4S)\Upsilon(4S) decays to \BBb ~pairs collected with the \babar detector at the PEP-II asymmetric-energy e+ee^+ e^- storage ring. We find no significant signal and set upper bounds for the branching fractions: B(B0DsDs+)<1.0×104,B(B0DsDs+)<1.3×104{\cal B}(B^{0} \to D_{s}^{-} D_{s}^{+}) < 1.0 \times 10^{-4}, {\cal B}(B^{0} \to D_{s}^{*-} D_{s}^{+}) < 1.3 \times 10^{-4} and B(B0DsDs+)<2.4×104{\cal B}(B^{0} \to D_{s}^{*-} D_{s}^{*+}) < 2.4 \times 10^{-4} at 90% confidence level.Comment: 8 pages, 2 figures, submitted to PRD-R
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