Longitudinal teacher education and workforce study (LTEWS) final report

The Longitudinal Teacher Education Workforce Study (LTEWS) investigated the career progression of graduate teachers from teacher education into teaching employment in all states and territories across Australia in 2012 and the first half of 2013, and tracked their perceptions, over time, of the relevance and effectiveness of their teacher education programs. Specifically, it investigated: The career progression of the 2011 teacher education graduates from teacher education into, and possible exit from, teaching employment, including their utilisation into teaching, their retention and attrition in teaching in their early years, and their geographic and schools sector mobility; and, The views of teacher education graduates over time on the relevance and effectiveness of their teacher education for their teaching employment, including the relationship between their views of their teacher education and their early career teaching career. &nbsp

Investigation of ammonium diuranate calcination with high temperature X-ray diffraction

The thermal decomposition of ammonium diuranate (ADU) in air is investigated using in-situ high-temperature x-ray diffraction (HT-XRD), thermogravimetry, and differential thermal analysis (TG/DTA). Data have been collected in the temperature range from 30 to 1000 °C, allowing to observe the sequence of phase transformations and to assess the energy changes involved in the calcination of ADU. The starting material 2UO3•NH3•3H2O undergoes a process involving several endothermic and exothermic reactions. In situ HT-XRD shows that amorphous UO3 is obtained after achieving complete dehydration at 300 °C, and denitration at about 450 °C. After cooling from heat treatment at 600 °C, a crystalline UO3 phase appears, as displayed by ex-situ XRD. The self-reduction of UO3 into orthorhombic U3O8 takes place at about 600 °C, but a long heat treatment or higher temperature is required to stabilize the structure of U3O8 at room temperature. U3O8 remains stable in air up to 850 °C. Above this temperature, oxygen losses lead to the formation of U3O8-x, as demonstrated by subtle changes in the diffraction pattern and by a mass loss recorded by TGA.JRC.E.6-Actinide researc

Sgr A East and its surroundings observed in X-rays

We report the results of an XMM-Newton observation of Sgr A East and its surroundings. The X-ray spectrum of Sgr A East is well represented with a two-temperature plasma model with temperatures of ~1 and ~4 keV. Only the iron abundance shows clear spatial variation; it concentrates in the core of Sgr A East. The derived plasma parameters suggest that Sgr A East originated in a single supernova. Around Sgr A East, there is a broad distribution of hard X-ray emission with a superimposed soft excess component extending away from the location of Sgr A East both above and below the plane. We discuss the nature of these structures as well as the close vicinity of Sgr A*.Comment: 7 pages, 3 figures, Accepted for publication in Advances in Space Research, as a proceeding paper for the 34th COSPAR E1.4 "High Energy Studies of Supernova Remnants and Neutron stars" held at Houston, Texas, USA during 10-19 Oct 2002; also found in http://www.star.le.ac.uk/~mas/research/paper/#Sakano2003cos

Laparoscopic Roux-en-Y Gastric Bypass for Morbid Obesity

Surgery is currently the only effective treatment for morbid obesity. The two most commonly accepted operations are the Roux-en-Y gastric bypass and vertical banded gastroplasty. Although multiple authors have reported on a laparoscopic approach to gastric banding, the Roux-en-Y gastric bypass is a complex operation to be replicated using laparoscopic techniques. In this article, we describe our technique of the Roux-en-Y gastric bypass using a laparoscopic approach in four cases

Stellar Kinematics of the Andromeda II Dwarf Spheroidal Galaxy

We present kinematical profiles and metallicity for the M31 dwarf spheroidal (dSph) satellite galaxy Andromeda II (And II) based on Keck DEIMOS spectroscopy of 531 red giant branch stars. Our kinematical sample is among the largest for any M31 satellite and extends out to two effective radii (r_eff = 5.3' = 1.1 kpc). We find a mean systemic velocity of -192.4+-0.5 km/s and an average velocity dispersion of sigma_v = 7.8+-1.1 km/s. While the rotation velocity along the major axis of And II is nearly zero (<1 km/s), the rotation along the minor axis is significant with a maximum rotational velocity of v_max=8.6+-1.8 km/s. We find a kinematical major axis, with a maximum rotational velocity of v_max=10.9+-2.4 km/s, misaligned by 67 degrees to the isophotal major axis. And II is thus the first dwarf galaxy with evidence for nearly prolate rotation with a v_max/sigma_v = 1.1, although given its ellipticity of epsilon = 0.10, this object may be triaxial. We measured metallicities for a subsample of our data, finding a mean metallicity of [Fe/H] = -1.39+- 0.03 dex and an internal metallicity dispersion of 0.72+-0.03 dex. We find a radial metallicity gradient with metal-rich stars more centrally concentrated, but do not observe a significant difference in the dynamics of two metallicity populations. And II is the only known dwarf galaxy to show minor axis rotation making it a unique system whose existence offers important clues on the processes responsible for the formation of dSphs.Comment: 14 pages, 10 figures, 4 tables, accepted for publication in Ap

Estimating selection pressures on HIV-1 using phylogenetic likelihood models

Human immunodeficiency virus (HIV-1) can rapidly evolve due to selection pressures exerted by HIV-specific immune responses, antiviral agents, and to allow the virus to establish infection in different compartments in the body. Statistical models applied to HIV-1 sequence data can help to elucidate the nature of these selection pressures through comparisons of non-synonymous (or amino acid changing) and synonymous (or amino acid preserving) substitution rates. These models also need to take into account the non-independence of sequences due to their shared evolutionary history. We review how we have developed these methods and have applied them to characterize the evolution of HIV-1 in vivo.To illustrate our methods, we present an analysis of compartment-specific evolution of HIV-1 env in blood and cerebrospinal fluid and of site-to-site variation in the gag gene of subtype C HIV-1

Generalizing the O(N)-field theory to N-colored manifolds of arbitrary internal dimension D

We introduce a geometric generalization of the O(N)-field theory that describes N-colored membranes with arbitrary dimension D. As the O(N)-model reduces in the limit N->0 to self-avoiding polymers, the N-colored manifold model leads to self-avoiding tethered membranes. In the other limit, for inner dimension D->1, the manifold model reduces to the O(N)-field theory. We analyze the scaling properties of the model at criticality by a one-loop perturbative renormalization group analysis around an upper critical line. The freedom to optimize with respect to the expansion point on this line allows us to obtain the exponent \nu of standard field theory to much better precision that the usual 1-loop calculations. Some other field theoretical techniques, such as the large N limit and Hartree approximation, can also be applied to this model. By comparison of low and high temperature expansions, we arrive at a conjecture for the nature of droplets dominating the 3d-Ising model at criticality, which is satisfied by our numerical results. We can also construct an appropriate generalization that describes cubic anisotropy, by adding an interaction between manifolds of the same color. The two parameter space includes a variety of new phases and fixed points, some with Ising criticality, enabling us to extract a remarkably precise value of 0.6315 for the exponent \nu in d=3. A particular limit of the model with cubic anisotropy corresponds to the random bond Ising problem; unlike the field theory formulation, we find a fixed point describing this system at 1-loop order.Comment: 57 pages latex, 26 figures included in the tex

In-Situ Focusing Inside a Thermal Vacuum Chamber

Traditionally, infrared (IR) space instruments have been focused by iterating with a number of different thickness shim rings in a thermal vacuum chamber until the focus meets requirements. This has required a number of thermal cycles that are very expensive as they tie up many integration and test (I&T)/ environmental technicians/engi neers work ing three shifts for weeks. Rather than creating a test shim for each iteration, this innovation replaces the test shim and can focus the instrument while in the thermal vacuum chamber. The focus tool consists of three small, piezo-actuated motors that drive two sets of mechanical interface flanges between the instrument optics and the focal- plane assembly, and three optical-displacement metrology sensors that can be read from outside the thermal vacuum chamber. The motors are used to drive the focal planes to different focal distances and acquire images, from which it is possible to determine the best focus. At the best focus position, the three optical displacement metrology sensors are used to determine the shim thickness needed. After the instrument leaves the thermal vacuum chamber, the focus tool is replaced with the precision-ground shim ring. The focus tool consists of two sets of collars, one that mounts to the backside of the interface flange of the instrument optics, and one that mounts to the backside of the interface flange of the focal plane modules. The collars on the instrument optics side have the three small piezo-actuated motors and the three optical displacement metrology systems. Before the instrument is focused, there is no shim ring in place and, therefore, no fasteners holding the focal plane modules to the cameras. Two focus tooling collars are held together by three strong springs. The Orbiting Carbon Observatory (OCO) mission spectrometer was focused this way (see figure). The motor described here had to be moved five times to reach an acceptable focus, all during the same thermal cycle, which was verified using pupil slicing techniques. A focus accuracy of .20.100 microns was achieved

Single-cell delineation of lineage and genetic identity in the mouse brain

During neurogenesis, mitotic progenitor cells lining the ventricles ofthe embryonic mouse brain undergo their final rounds of cell division, giving rise to a wide spectrum of postmitotic neurons and glia(1,2). The link between developmental lineage and cell-type diversity remains an open question. Here we used massively parallel tagging of progenitors to track clonal relationships and transcriptomic signatures during mouse forebrain development. We quantified clonal divergence and convergence across all major cell classes postnatally, and found diverse types of GABAergic neuron that share a common lineage. Divergence of GABAergic clones occurred during embryogenesis upon cell-cycle exit, suggesting that differentiation into subtypes is initiated as a lineage-dependent process at the progenitor cell level

The Obturator Guiding Technique in Percutaneous Endoscopic Lumbar Discectomy

In conventional percutaneous disc surgery, introducing instruments into disc space starts by inserting a guide needle into the triangular working zone. However, landing the guide needle tip on the annular window is a challenging step in endoscopic discectomy. Surgeons tend to repeat the needling procedure to reach an optimal position on the annular target. Obturator guiding technique is a modification of standard endoscopic lumbar discectomy, in which, obturator is used to access triangular working zone instead of a guide needle. Obturator guiding technique provides more vivid feedback and easy manipulation. This technique decreases the steps of inserting instruments and takes safer route from the peritoneum