Varying c and Particle Horizons

We explore what restrictions may impose the second law of thermodynamics on varying speed of light theories. We find that the attractor scenario solving the flatness problem is consistent with the generalized second law at late time.Comment: Latex file, 8 pages, to be published in Physics Letters

Attitude control analysis of tethered de-orbiting

The increase of satellites and rocket upper stages in low earth orbit (LEO) has also increased substantially the danger of collisions in space. Studies have shown that the problem will continue to grow unless a number of debris are removed every year. A typical active debris removal (ADR) mission scenario includes launching an active spacecraft (chaser) which will rendezvous with the inactive target (debris), capture the debris and eventually deorbit both satellites. Many concepts for the capture of the debris while keeping a connection via a tether, between the target and chaser have been investigated, including harpoons, nets, grapples and robotic arms. The paper provides an analysis on the attitude control behaviour for a tethered de-orbiting mission based on the ESA e.Deorbit reference mission, where Envisat is the debris target to be captured by a chaser using a net which is connected to the chaser with a tether. The paper provides novel insight on the feasibility of tethered de-orbiting for the various mission phases such as stabilization after capture, de-orbit burn (plus stabilization), stabilization during atmospheric pass, highlighting the importance of various critical mission parameters such as the tether material. It is shown that the selection of the appropriate tether material while using simple controllers can reduce the effort needed for tethered deorbiting and can safely control the attitude of the debris/chaser connected with a tether, without the danger of a collision

Discrete Nonholonomic LL Systems on Lie Groups

This paper applies the recently developed theory of discrete nonholonomic mechanics to the study of discrete nonholonomic left-invariant dynamics on Lie groups. The theory is illustrated with the discrete versions of two classical nonholonomic systems, the Suslov top and the Chaplygin sleigh. The preservation of the reduced energy by the discrete flow is observed and the discrete momentum conservation is discussed.Comment: 32 pages, 13 figure

Characterization of the NASA Langley Arc Heated Scramjet Test Facility Using NO PLIF

The nitric oxide planar laser-induced fluorescence (NO PLIF) imaging was used to characterize the air flow of the NASA Langley Arc Heated Scramjet Test Facility (AHSTF) configured with a Mach 6 nozzle. The arc raises the enthalpy of the test gas in AHSTF, producing nitric oxide. Nitric oxide persists as the temperature drops through the nozzle into the test section. NO PLIF was used to qualitatively visualize the flowfield at different experimental conditions, measure the temperature of the gas flow exiting the facility nozzle, and visualize the wave structure downstream of the nozzle at different operating conditions. Uniformity and repeatability of the nozzle flow were assessed. Expansion and compression waves on the free-jet shear layer as the nozzle flow expands into the test section were visualized. The main purpose of these experiments was to assess the uniformity of the NO in the freestream gas for planned experiments, in which NO PLIF will be used for qualitative fuel-mole-fraction sensitive imaging. The shot-to-shot fluctuations in the PLIF signal, caused by variations in the overall laser intensity as well as NO concentration and temperature variations in the flow was 20-25% of the mean signal, as determined by taking the standard deviation of a set of images obtained at constant conditions and dividing by the mean. The fluctuations within individual images, caused by laser sheet spatial variations as well as NO concentration and temperature variations in the flow, were about 28% of the mean in images, determined by taking standard deviation within individual images, dividing by the mean in the same image and averaged over the set of images. Applying an averaged laser sheet intensity correction reduced the within-image intensity fluctuations to about 10% suggesting that the NO concentration is uniform to within 10%. There was no significant difference in flow uniformity between the low and high enthalpy settings. While not strictly quantitative, the temperature maps show qualitative agreement with the computations of the flow

THE OPTICAL-UV EMISSIVITY OF QUASARS: DEPENDENCE ON BLACK HOLE MASS AND RADIO LOUDNESS

We analyzed a large sample of radio-loud and radio-quiet quasar spectra at redshift 1.0 < z < 1.2 to compare the inferred underlying quasar continuum slopes (after removal of the host galaxy contribution) with accretion disk models. The latter predict redder (decreasing) alpha_3000 continuum slopes (L_\nu~\nu^alpha at 3000Ang) with increasing black hole mass, bluer alpha_3000 with increasing luminosity at 3000Ang, and bluer alpha_3000 with increasing spin of the black hole, when all other parameters are held fixed. We find no clear evidence for any of these predictions in the data. In particular we find that: (i) alpha_3000 shows no significant dependence on black hole mass or luminosity. Dedicated Monte Carlo tests suggest that the substantial observational uncertainties in the black hole virial masses can effectively erase any intrinsic dependence of alpha_3000 on black hole mass, in line with some previous studies. (ii) The mean slope alpha_3000 of radio-loud sources, thought to be produced by rapidly spinning black holes, is comparable to, or even redder than, that of radio-quiet quasars. Indeed, although quasars appear to become more radio loud with decreasing luminosity, we still do not detect any significant dependence of alpha_3000 on radio loudness. The predicted mean alpha_3000 slopes tend to be bluer than in the data. Disk models with high inclinations and dust extinction tend to produce redder slopes closer to empirical estimates. Our mean alpha_3000 values are close to the ones independently inferred at z<0.5 suggesting weak evolution with redshift, at least for moderately luminous quasars.This is the author accepted manuscript. The final version is available from the Institute of Physics via http://dx.doi.org/10.3847/2041-8205/818/1/L

Rapid-Onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD): Exome sequencing of trios, monozygotic twins and tumours

BACKGROUND: Rapid-onset Obesity with Hypothalamic Dysfunction, Hypoventilation, and Autonomic Dysregulation (ROHHAD) is thought to be a genetic disease caused by de novo mutations, though causative mutations have yet to be identified. We searched for de novo coding mutations among a carefully-diagnosed and clinically homogeneous cohort of 35 ROHHAD patients. METHODS: We sequenced the exomes of seven ROHHAD trios, plus tumours from four of these patients and the unaffected monozygotic (MZ) twin of one (discovery cohort), to identify constitutional and somatic de novo sequence variants. We further analyzed this exome data to search for candidate genes under autosomal dominant and recessive models, and to identify structural variations. Candidate genes were tested by exome or Sanger sequencing in a replication cohort of 28 ROHHAD singletons. RESULTS: The analysis of the trio-based exomes found 13 de novo variants. However, no two patients had de novo variants in the same gene, and additional patient exomes and mutation analysis in the replication cohort did not provide strong genetic evidence to implicate any of these sequence variants in ROHHAD. Somatic comparisons revealed no coding differences between any blood and tumour samples, or between the two discordant MZ twins. Neither autosomal dominant nor recessive analysis yielded candidate genes for ROHHAD, and we did not identify any potentially causative structural variations. CONCLUSIONS: Clinical exome sequencing is highly unlikely to be a useful diagnostic test in patients with true ROHHAD. As ROHHAD has a high risk for fatality if not properly managed, it remains imperative to expand the search for non-exomic genetic risk factors, as well as to investigate other possible mechanisms of disease. In so doing, we will be able to confirm objectively the ROHHAD diagnosis and to contribute to our understanding of obesity, respiratory control, hypothalamic function, and autonomic regulation. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13023-015-0314-x) contains supplementary material, which is available to authorized users

BBF RFC 106: A Standard Type IIS Syntax for Plants

Here we define a standard syntax for assembling standard parts for expression in plant cells, extensible to all other eukaryotes. Variations of the Type IIS mediated cloning method known as Golden Gate Cloning, most notably Golden Braid (GB2.0) and Golden Gate Modular Cloning (MoClo) are in common use, particularly for the assembly of plasmids for delivery to plant cells. Many characterised plant parts compatible with Type IIS mediated assembly are available outside of the Registry of Standard Parts, as well as plasmids with the features necessary for delivery of DNA to plants cells via the shuttle chassis, Agrobacterium tumefaciens. This RFC describes a consensus Type IIS syntax for plant parts to allow assembly into complete eukaryotic transcriptional units in plasmid vectors that contain the necessary features for transfection of plant chassis. We use Marchantia polymorpha, a primitive and easy-to-engineer liverwort and Nicotiana benthamiana a model plant as exemplar chassis

A Neptune-mass Planet Orbiting the Nearby G Dwarf HD16417

Precision Doppler measurements from an intensive 48 night "Rocky Planet Search" observing campaign on the Anglo-Australian Telescope (AAT) have revealed the presence of a low-mass exoplanet orbiting the G1 dwarf HD16417. Subsequent Doppler observations with the AAT, as well as independent observations obtained by the Keck Planet Search, have confirmed this initial detection and refine the orbital parameters to period 17.24+/-0.01 d, eccentricity 0.20+/-0.09, orbital semi-major axis 0.14+/-0.01 AU and minimum planet mass 22.1+/-2.0 Mearth. HD 16417 raises the number of published exoplanets with minimum masses of less than 25 Mearth to eighteen. Interestingly, the distribution of detected sub-25 Mearth planets over the spectral types G, K and M is almost uniform. The detection of HD 16417b by an intensive observing campaign clearly demonstrates the need for extended and contiguous observing campaigns when aiming to detect low-amplitude Doppler planets in short period orbits. Perhaps most critically it demonstrates that the search for low-mass Doppler planets will eventually require these traditional "bright-time" projects to extend throughout dark lunations.Comment: To appear in Ap

Profound Context-Dependent Plasticity of Mitral Cell Responses in Olfactory Bulb

On the basis of its primary circuit it has been postulated that the olfactory bulb (OB) is analogous to the retina in mammals. In retina, repeated exposure to the same visual stimulus results in a neural representation that remains relatively stable over time, even as the meaning of that stimulus to the animal changes. Stability of stimulus representation at early stages of processing allows for unbiased interpretation of incoming stimuli by higher order cortical centers. The alternative is that early stimulus representation is shaped by previously derived meaning, which could allow more efficient sampling of odor space providing a simplified yet biased interpretation of incoming stimuli. This study helps place the olfactory system on this continuum of subjective versus objective early sensory representation. Here we show that odor responses of the output cells of the OB, mitral cells, change transiently during a go–no-go odor discrimination task. The response changes occur in a manner that increases the ability of the circuit to convey information necessary to discriminate among closely related odors. Remarkably, a switch between which of the two odors is rewarded causes mitral cells to switch the polarity of their divergent responses. Taken together these results redefine the function of the OB as a transiently modifiable (active) filter, shaping early odor representations in behaviorally meaningful ways