750 research outputs found

    Like a Carsic River: Gay Independent Cinema from Underground Films to New Queer Cinema and Beyond

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    Like a Carsic River: Gay Independent Cinema from Underground Films to New Queer Cinema and Beyond

    Collaboration between a human group and artificial intelligence can improve prediction of multiple sclerosis course. A proof-of-principle study

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    Background: Multiple sclerosis has an extremely variable natural course. In most patients, disease starts with a relapsing-remitting (RR) phase, which proceeds to a secondary progressive (SP) form. The duration of the RR phase is hard to predict, and to date predictions on the rate of disease progression remain suboptimal. This limits the opportunity to tailor therapy on an individual patient's prognosis, in spite of the choice of several therapeutic options. Approaches to improve clinical decisions, such as collective intelligence of human groups and machine learning algorithms are widely investigated. Methods: Medical students and a machine learning algorithm predicted the course of disease on the basis of randomly chosen clinical records of patients that attended at the Multiple Sclerosis service of Sant'Andrea hospital in Rome. Results: A significant improvement of predictive ability was obtained when predictions were combined with a weight that depends on the consistence of human (or algorithm) forecasts on a given clinical record. Conclusions: In this work we present proof-of-principle that human-machine hybrid predictions yield better prognoses than machine learning algorithms or groups of humans alone. To strengthen this preliminary result, we propose a crowdsourcing initiative to collect prognoses by physicians on an expanded set of patients

    The antimicrobial photodynamic therapy in the treatment of peri-implantitis

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    The aim of this study is to demonstrate the effectiveness of addition of the antimicrobial photodynamic therapy to the conventional approach in the treatment of peri-implantitis. Materials and Methods. Forty patients were randomly assigned to test or control groups. Patients were assessed at baseline and at six (T1), twelve (T2), and twenty-four (T3) weeks recording plaque index (PlI), probing pocket depth (PPD), and bleeding on probing (BOP); control group received conventional periodontal therapy, while test group received photodynamic therapy in addition to it. Result. Test group showed a 70% reduction in the plaque index values and a 60% reduction in PD values compared to the baseline. BOP and suppuration were not detectable. Control group showed a significative reduction in plaque index and PD. Discussion. Laser therapy has some advantages in comparison to traditional therapy, with faster and greater healing of the wound. Conclusion. Test group showed after 24 weeks a better value in terms of PPD, BOP, and PlI, with an average pocket depth value of 2 mm, if compared with control group (3 mm).Our results suggest that antimicrobial photodynamic therapy with diode laser and phenothiazine chloride represents a reliable adjunctive treatment to conventional therapy. Photodynamic therapy should, however, be considered a coadjuvant in the treatment of peri-implantitis associated with mechanical (scaling) and surgical (grafts) treatments

    Surface Operators in Superspace

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    We generalize the geometrical formulation of Wilson loops recently introduced in arXiv:2003.01729v2 to the description of Wilson Surfaces. For N=(2,0) theory in six dimensions, we provide an explicit derivation of BPS Wilson Surfaces with non-trivial coupling to scalars, together with their manifestly supersymmetric version. We derive explicit conditions which allow to classify these operators in terms of the number of preserved supercharges. We also discuss kappa-symmetry and prove that BPS conditions in six dimensions arise from kappa-symmetry invariance in eleven dimensions. Finally, we discuss super-Wilson Surfaces - and higher dimensional operators - as objects charged under global pp-form (super)symmetries generated by tensorial supercurrents. To this end, the construction of conserved supercurrents in supermanifolds and of the corresponding conserved charges is developed in details.Comment: 47 pages, added references, adjusted notation in App

    The construction of gender roles and sexual dissidence on TV: using Anglo-Saxon paradigms to re-read Catalan and Spanish texts

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    Taking as a starting point an interpretation of the television medium as an Ideological State Apparatus, in my thesis I examine how gender roles and sexual dissidence are constructed in Spanish and Catalan television series. I focus on a corpus of narrative materials through a perspective informed by theories elaborated by Anglo-Saxon scholars in gender studies and studies of sexual dissidence. In my first chapter, which focuses on the construction of gender roles in Catalan soap operas, I apply the analytical paradigms that Anglo-Saxon feminist scholars have elaborated for the content of soap operas and the viewing practices of their audiences to a corpus of material which has rarely been analysed through this perspective. In the second chapter, which focuses on the construction of sexual dissidence in Spanish and Catalan television series, I aim to challenge ‘essentialist’ paradigms which have so far dominated the examination of the construction of sexual dissidence in television series. Moreover, I query the pedagogical aspirations of public-funded television and the contradictions often involved in the application of this remit. My theoretical base encompasses the work of scholars as diverse as Christine Geraghty and Alberto Mira. Studies by Ricardo Llamas, Charlotte Brundson, and Dorothy Hobson, in particular, help me to articulate my comparative analysis of television content in Spanish and Catalan contexts. In conclusion, the aim of my thesis is to address the role performed by television in the construction of meanings which surround gender issues and sexual dissidence. This is a timely exercise because gender studies and studies of sexual dissidence are fairly recent fields in Spanish and Catalan academia and television has been largely disregarded, especially as far as the analysis of characters and storylines is concerned. My thesis aims to be a contribution to these fields in the Spanish and Catalan contexts

    Recent advances in smart biotechnology: Hydrogels and nanocarriers for tailored bioactive molecules depot

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    Over the past ten years, the global biopharmaceutical market has remarkably grown, with ten over the top twenty worldwide high performance medical treatment sales being biologics. Thus, biotech R&D (research and development) sector is becoming a key leading branch, with expanding revenues. Biotechnology offers considerable advantages compared to traditional therapeutic approaches, such as reducing side effects, specific treatments, higher patient compliance and therefore more effective treatments leading to lower healthcare costs. Within this sector, smart nanotechnology and colloidal self-assembling systems represent pivotal tools able to modulate the delivery of therapeutics. A comprehensive understanding of the processes involved in the self assembly of the colloidal structures discussed therein is essential for the development of relevant biomedical applications. In this review we report the most promising and best performing platforms for specific classes of bioactive molecules and related target, spanning from siRNAs, gene/plasmids, proteins/growth factors, small synthetic therapeutics and bioimaging probes.Istituto Italiano di Tecnologia (IIT)COST Action [CA 15107]People Program (Marie Curie Actions) of the European Union's Seventh Framework Program under REA [606713 BIBAFOODS]Portuguese Foundation for Science and Technology (FCT) [PTDC/AGR-TEC/4814/2014, IF/01005/2014]Fundacao para a Ciencia e Tecnologia [SFRH/BPD/99982/2014]Danish National Research Foundation [DNRF 122]Villum Foundation [9301]Italian Ministry of Instruction, University and Research (MIUR), PRIN [20109PLMH2]"Fondazione Beneficentia Stiftung" VaduzFondo di Ateneo FRAFRAinfo:eu-repo/semantics/publishedVersio

    On the Importance of Investigating Data Structure in Miniaturized NIR Spectroscopy Measurements of Food: The Case Study of Sugar

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    Alongside the increasing proofs of efficacy of miniaturized NIR instruments in food-related scenarios, it is progressively growing the number of end-users, even incentivized by the low-cost of the sensors. While attention is paid to the analytical protocol–from sampling to data collection, up to the data processing, the importance of error investigation in raw data is generally underestimated. Understanding the sources and the structure of uncertainty related to the raw data improves the quality of measurements and suggests the correct planning of the experiments, as well as helps in chemometric model development. The goal of chemometric modeling is to separate information from noise; therefore, a description of the nature of measurement error structure is necessary. Among the different approaches, we present the study of the Error Covariance Matrices (ECMs) and their decomposition in a bilinear structure as a powerful method to study the main sources of variability when using miniaturized NIR sensors in the actual way of use. Granulated and lump sugar samples were chosen as the case study and analyzed with two miniaturized spectrometers working in the NIR regions around 1350–2550 nm and 900–1750 nm, respectively, in dispersive reflectance mode. Results show that having some insights on multivariate measurement errors associated with spectra could be interesting in paving the way for several applications

    Survey of the Ridracoli Dam: UAV – Based Photogrammetry and Traditional Topographic Techniques in the Inspection of Vertical Structures*

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    The inspection of strategic works such as dams is of vital importance both for their maintenance and for the safety of downstream populations. The reduced accessibility, both for uptake needs and for their strategic nature, and the large time needed for an inspection by traditional method do not facilitate the investigation of this type of structures. The new unmanned aerial vehicle (UAV) technology, equipped with high-performance cameras, allows for rapid photographic coverage of the whole dam system. Apart from the placement on the structure of a high number of markers, the correct geo-referencing and validation of the model also requires an important terrestrial topographic campaign by total station, Global Positioning System and laser scanner. Punctual, linear and surface analysis shows the high accuracy of the drone acquiring technique. The product is suitable for a detailed survey of the conservation status of the materials and the complete metric reconstruction of the dam system and the adjacent land. The present work explains firstly a UAV acquisition and then the first dense point cloud validation procedure of a concrete arch gravity dam. The Ridracoli dam is the object of the survey, located in the village of Santa Sofia in central Italy

    The Relationship between Compulsive Behaviour and Internet Addiction

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    A variety of behavioural and emotional problems among university students is due to Internet Addiction (Alavi et al. 2012, Rusconi et al. 2012). In 2013 a survey is conducted on a sample of 532 students of University of L’Aquila. The purpose is to investigate Internet use patterns and the correlation between Internet Addiction disorder and compulsive behaviour. Two self-administered questionnaires are used: the Internet Addiction Test and the Cognitive Behavioural Assessment 2.0. 517 students show signs of Internet Addiction, which is moderate for 31% of respondents and severe for 1% of them. 5% shows intrusive thoughts and compulsive behaviours. The symptoms of obsessive-compulsive disorder are statistically associated with Internet Addiction (chi² test=23.53, p=0.000). Among young people there is a relationship between compulsive behaviour and Internet Addiction. This relationship has significant effects on treatment of Internet Addiction
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