Nanoestructuras autoensambladas mediante epitaxia por haces moleculares de InAs sobre substratos de GaAs(001): de los puntos cuánticos a los anillos cuánticos

Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Ciencias, Departamento de Física de Materiales. Fecha de lectura 19-10-200

Analysis and performance of lumped-element kinetic inductance detectors for W-band

Lumped-element superconducting resonators are a promising technology for their use in millimeter-wave observations and quantum computing applications that require large arrays of extremely sensitive detectors. Among them, lumped-element kinetic inductance detectors (LEKIDs) have shown good performance in the submillimeter band in several earth-based telescopes. In this work, LEKIDs for their use as millimeter-wave receivers of astronomical applications are presented. LEKID arrays using a thin bilayer of superconducting titanium/aluminum (Ti/Al), deposited on the silicon substrate, have been designed and fabricated. The design of a dual-polarization LEKID with the goal of detection at the W -band for two orthogonal polarizations is described and a fabricated array has demonstrated absorption at ambient temperature. Also, an approximate design methodology of the coupling parameter for LEKIDs' readout, essential for dynamic range optimization of the detector under millimeter-wave radiation, is proposed. In addition, the resonance characteristics and coupling factor of the fabricated superconducting resonators using high-quality internal factor Qi under cryogenic temperatures have been analyzed. The design guidelines in this work are applicable to other LEKID arrays, and the presented superconducting Ti/Al thin-film LEKIDs can be used in future receiver arrays in the millimeter bands.This work was supported by Ministry of Science, Innovation and Universities under Grants ESP2017-83921-C2-2-R, ESP2017-86582-C4-1-R, ESP2017-86582-C4-3-R, ESP2017-92706-EXP, AYA2017-92153-EXP, “Severo Ochoa” Programme for Centres of Excellence in R&D (MINECO, Grant SEV-2016-0686). By Comunidad de Madrid under Grant P2018/NMT-4291. D.G. and A.G also acknowledge Grant DEFROST N62909-19-1-2053 from ONRGlobal. A.G. acknowledges IJCI-2017-33991

La Imagen y la Narrativa como Herramientas para el Abordaje Psicosocial en Escenarios de Violencia. Departamento de Santander.

El presente documento hace referencia a la actividad Escenario 2: “abordaje de contextos desde los enfoques narrativos”, del Diplomado Acompañamiento Psicosocial en Escenarios de Violencia, cuyo propósito es brindar elementos y herramientas conceptuales, metodológicas y disciplinares en torno a evaluación de eventos psicosociales traumáticos, la potenciación de recursos de afrontamiento individual y colectivo, y la articulación de redes de apoyo. Se presenta a continuación un análisis del relato de Ana Ligia, tomado del libro “Voces: historias de violencia y esperanza en Colombia”, el cual muestra la forma en que la violencia llega a su vida y todo da un giro en su familia y su comunidad. El caso es uno de los muchos acontecidos en Colombia, donde mujeres con sus hijos son desplazados de sus territorios y deben buscar otros horizontes que en medio de las adversidades logran superar. Ana Ligia se convierte en un ejemplo de motivación y superación para muchas mujeres que viven experiencias traumáticas, logra inspirar sueños a través de su poesía. De igual forma se formulan preguntas circulares, reflexivas y estratégicas, teniendo en cuenta el caso referido anteriormente. Posteriormente se expone una propuesta de abordaje psicosocial desde diferentes estrategias en el caso de Peñas Coloradas, tomado de: “El Estado declaró al Ejercito dueño temporal de nuestro caserío y nos condenó al destierro”. 2019. Comisión de la verdad. Es un caso en el que toda una comunidad es desplazada de sus tierras a causa de los despliegues militares y bombardeos, encuentros de las FARC y el ejército, teniendo que llegar a un sitio de asentamiento y con la esperanza de volver a su tierra, la cual se vio interrumpida por cuanto Peñas Coloradas fue entregada en comodato al Ejército por una década, con una firma y un papel el Estado declaraba sus tierras como dueñas temporales a las Fuerzas Militares, y de esta manera se renovó por otros diez años, quedando del caserío que con tanto esfuerzo habían levantado, solo los escombros y recuerdos. Por último, se comparte un informe analítico y reflexivo a partir de la experiencia de foto voz en el Departamento de Santander.This document refers to the activity Scenario 2: “Accost to contexts from narrative approaches”, of the Diploma Course on Psychosocial Accompaniment in Violence Scenarios, whose purpose is to provide elements and conceptual, methodological and disciplinary tools around the evaluation of traumatic psychosocial events , the empowerment of individual and collective coping resources, and the articulation of support networks. An analysis of Ana Ligia's story is presented below, taken from the book “Voices: Stories of violence and hope in Colombia” which shows how violence comes into her life and how everything turns around in her family and community. The case is one of many that occurred in Colombia, where women with their children are displaced from their territories and must seek other horizons that in the midst of adversity they manage to overcome. Ana Ligia becomes an example of motivation and improvement for many women who live traumatic experiences, she manages to inspire dreams through her poetry. In the same way, circular, reflective and strategic questions are formulated, taking into account the case referred to above. Subsequently, a proposal for a psychosocial approach is presented from different strategies in the case of Peñas Coloradas, taken from: "The State declared the Army temporary owner of our hamlet and sentenced us to exile." 2019. Truth Commission. It is a case in which an entire community is displaced from their lands due to military deployments and bombings, encounters of the FARC and the army, having to reach a settlement site and with the hope of returning to their land, the which was interrupted by the fact that Peñas Coloradas was given as a loan to the Army for a decade, with a signature and a paper the State declared their lands as temporary owners to the Military Forces, and in this way it was renewed for another ten years, remaining from the hamlet that with so much effort they had raised, only the rubble and memories. Finally, an analytical and reflective report is shared based on the experience of photovoice in the Department of Santander

Bi-layer kinetic inductance detectors for W-band

An array of superconducting kinetic inductance detectors (KID) has been fabricated and it has demonstrated absorption at W-Band. The use of a bi-layer structure based on aluminum (AI) and titanium (Ti) shows a lower superconducting critical temperature (T c ), which allows the detection at W-band. A design methodology is presented taking into account the KID geometry in order to maximize the absorption and a dual-polarization KID has been designed using the proposed methodology. Two prototypes of KID on Silicon substrate have been fabricated showing a good agreement between measurement and simulation results. The measurements at room temperature from 65 to 110 GHz show the matching at the frequency band, while dark cryogenic characterization demonstrated the low frequency design.The authors acknowledge financial supports: Ministry of Science, Innovation and Universities Grants ESP2017-83921-C2-2-R, ESP2017-86582-C4-1-R, ESP2017-86582-C4-3-R, MAT2017-85617-R, ESP2017-92706-EXP, AYA2017-92153-EXP and from Comunidad de Madrid through Grant P2018/NMT-4291 TEC2-SPACE-CM. A.G. acknowledges IJCI-2017-33991; IMDEA Nanociencia acknowledges support from the “Severo Ochoa” Programme for Centres of Excellence in R&D (MINECO, Grant SEV-2016-0686). D.G. and A.G also acknowledge Grant DEFROST N62909-19-1-2053 from ONR-Global

Planta de producció d'àcid acetilsalicílic

L'objectiu d'aquest treball ha estat el disseny d'una planta de producció d'àcid acetilsalicílic a partir, principalment, de fenol, hidròxid de sodi, anhidre acètic i CO2, situada a Reus. La planta ha estat dissenyada per a una producció de 30.000 Tn/any d'àcid acetilsalicílic en forma d'API i empaquetat en bidons de 200 Kg

Histological and biochemical evaluation of plasma rich in growth factors treatment for grade II muscle injuries in sheep.

The purpose of this study was to perform a histological and biochemical evaluation of the influence of plasma rich in growth factors (PRGF) on muscle regeneration process after a surgically induced grade II muscle laceration. A randomized, single blind, controlled experimental research was conducted including twenty-one adult healthy sheep, randomly divided in three groups (n = 7). A grade II surgical section was performed in the biceps femoris muscle of both hindlimbs. After two days (basal time), intralesional infiltration of autologous PRGF or Saline solution was randomly administered in both hindlimbs. Treatment was repeated once a week. Animal groups were euthanized at 1 (T1), 2 (T2) or 4 (T4) weeks. Histological assessment showed that PRGF intralesional injection induced a significant decrease of inflammatory cells density, significant higher centrally nucleated fibers percentage and significantly smaller fibrotic areas compared to Saline-treated muscles at T1, T2 and T4. Also, lower vascular density, with lower capillaries cross-sectional area, in PRGF group compared to Saline was observed. Biochemical analysis revealed a significant higher expression level of MYOD1, MYF5 and MYOG genes in PRGF groups at T1 compared to Saline treated muscles. At ultrastructural level, PRGF groups presented scarce edema and loss of connective tissue structure, as well as higher mitochondrial density adequately associated to the sarcomere unit in contrast to the Saline group. In conclusion, histological, biochemical, and ultrastructural results showed that PRGF treatment improved muscle regeneration process leading to more mature histological aspect in newly formed muscle tissue after a surgically induced grade II muscle injury

Native American ancestry significantly contributes to neuromyelitis optica susceptibility in the admixed Mexican population

Neuromyelitis Optica (NMO) is an autoimmune disease with a higher prevalence in non-European populations. Because the Mexican population resulted from the admixture between mainly Native American and European populations, we used genome-wide microarray, HLA high-resolution typing and AQP4 gene sequencing data to analyze genetic ancestry and to seek genetic variants conferring NMO susceptibility in admixed Mexican patients. A total of 164 Mexican NMO patients and 1,208 controls were included. On average, NMO patients had a higher proportion of Native American ancestry than controls (68.1% vs 58.6%; p = 5 × 10–6). GWAS identified a HLA region associated with NMO, led by rs9272219 (OR = 2.48, P = 8 × 10–10). Class II HLA alleles HLA-DQB1*03:01, -DRB1*08:02, -DRB1*16:02, -DRB1*14:06 and -DQB1*04:02 showed the most significant associations with NMO risk. Local ancestry estimates suggest that all the NMO-associated alleles within the HLA region are of Native American origin. No novel or missense variants in the AQP4 gene were found in Mexican patients with NMO or multiple sclerosis. To our knowledge, this is the first study supporting the notion that Native American ancestry significantly contributes to NMO susceptibility in an admixed population, and is consistent with differences in NMO epidemiology in Mexico and Latin America.Fil: Romero Hidalgo, Sandra. Instituto Nacional de Medicina Genómica; MéxicoFil: Flores Rivera, José. Instituto Nacional de Neurología y Neurocirugía; MéxicoFil: Rivas Alonso, Verónica. Instituto Nacional de Neurología y Neurocirugía; MéxicoFil: Barquera, Rodrigo. Max Planck Institute For The Science Of Human History; Alemania. Instituto Nacional de Antropología e Historia; MéxicoFil: Villarreal Molina, María Teresa. Instituto Nacional de Medicina Genómica; MéxicoFil: Antuna Puente, Bárbara. Instituto Nacional de Medicina Genómica; MéxicoFil: Macias Kauffer, Luis Rodrigo. Universidad Nacional Autónoma de México; MéxicoFil: Villalobos Comparán, Marisela. Instituto Nacional de Medicina Genómica; MéxicoFil: Ortiz Maldonado, Jair. Instituto Nacional de Neurología y Neurocirugía; MéxicoFil: Yu, Neng. American Red Cross; Estados UnidosFil: Lebedeva, Tatiana V.. American Red Cross; Estados UnidosFil: Alosco, Sharon M.. American Red Cross; Estados UnidosFil: García Rodríguez, Juan Daniel. Instituto Nacional de Medicina Genómica; MéxicoFil: González Torres, Carolina. Instituto Nacional de Medicina Genómica; MéxicoFil: Rosas Madrigal, Sandra. Instituto Nacional de Medicina Genómica; MéxicoFil: Ordoñez, Graciela. Neuroimmunología, Instituto Nacional de Neurología y Neurocirugía; MéxicoFil: Guerrero Camacho, Jorge Luis. Instituto Nacional de Neurología y Neurocirugía; MéxicoFil: Treviño Frenk, Irene. American British Cowdray Medical Center; México. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: Escamilla Tilch, Monica. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: García Lechuga, Maricela. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: Tovar Méndez, Víctor Hugo. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: Pacheco Ubaldo, Hanna. Instituto Nacional de Antropología E Historia. Escuela Nacional de Antropología E Historia; MéxicoFil: Acuña Alonzo, Victor. Instituto Nacional de Antropología E Historia. Escuela Nacional de Antropología E Historia; MéxicoFil: Bortolini, María Cátira. Universidade Federal do Rio Grande do Sul; BrasilFil: Gallo, Carla. Universidad Peruana Cayetano Heredia; PerúFil: Bedoya Berrío, Gabriel. Universidad de Antioquia; ColombiaFil: Rothhammer, Francisco. Universidad de Tarapacá; ChileFil: Gonzalez-Jose, Rolando. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Instituto Patagónico de Ciencias Sociales y Humanas; ArgentinaFil: Ruiz Linares, Andrés. Colegio Universitario de Londres; Reino UnidoFil: Canizales Quinteros, Samuel. Universidad Nacional Autónoma de México; MéxicoFil: Yunis, Edmond. Dana Farber Cancer Institute; Estados UnidosFil: Granados, Julio. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: Corona, Teresa. Instituto Nacional de Neurología y Neurocirugía; Méxic

Expression of Interest: The Canfranc Axion Detection Experiment (CADEx)

Trabajo presentado al 29th Meeting of the LSC Scientific Committee, celebrado online del 30 de noviembre al 1 de diciembre de 2021.Peer reviewe