E-readiness in construction (ERiC) : self-assessment framework for UK small and medium enterprise building services providers

The construction industry’s ability to innovate in order to improve its practices has been widely debated. As organisations in other sectors globally are addressing technology challenges, is the UK construction industry e-ready? Of particular concern is the plethora of small and medium enterprises (SME) that constitute over 80% of the UK construction industry. There are noticeable SME laggards in the uptake of new processes and technologies. This paper aims to assess the e-readiness levels of UK SME building services provider in order to leverage the advantages of technology opportunities in the future. The resultant self-assessment ERiC framework enables SMEs to quantify and measure e-readiness from an organisation, technical and process perspective

Target highlights in CASP13: experimental target structures through the eyes of their authors

The functional and biological significance of selected CASP13 targets are described by the authors of the structures. The structural biologists discuss the most interesting structural features of the target proteins and assess whether these features were correctly reproduced in the predictions submitted to the CASP13 experiment

Systematic Review of Medicine-Related Problems in Adult Patients with Atrial Fibrillation on Direct Oral Anticoagulants

New oral anticoagulant agents continue to emerge on the market and their safety requires assessment to provide evidence of their suitability for clinical use. There-fore, we searched standard databases to summarize the English language literature on medicine-related problems (MRPs) of direct oral anticoagulants DOACs (dabigtran, rivaroxban, apixban, and edoxban) in the treatment of adults with atri-al fibrillation. Electronic databases including Medline, Embase, International Pharmaceutical Abstract (IPA), Scopus, CINAHL, the Web of Science and Cochrane were searched from 2008 through 2016 for original articles. Studies pub-lished in English reporting MRPs of DOACs in adult patients with AF were in-cluded. Seventeen studies were identified using standardized protocols, and two reviewers serially abstracted data from each article. Most articles were inconclusive on major safety end points including major bleeding. Data on major safety end points were combined with efficacy. Most studies inconsistently reported adverse drug reactions and not adverse events or medication error, and no definitions were consistent across studies. Some harmful drug effects were not assessed in studies and may have been overlooked. Little evidence is provided on MRPs of DOACs in patients with AF and, therefore, further studies are needed to establish the safety of DOACs in real-life clinical practice

E-readiness in construction: an incongruous paradigm of variables

The construction industry has witnessed unprecedented levels of technological change over the last 10 years in particular, the corollary of which has required key decision makers to fundamentally re-think the way they: (a) have undertaken business in the past; (b) are currently doing business at the moment; and, (c) will need to change their business practices in order to compete in the future. This research attempts to understand this trichotomy, with a specific emphasis on understanding key decision makers' perception of e-readiness within the context of the construction industry. Research findings highlighted the importance of People, Process and Technology, along with five core enablers that are deemed priority areas for operationalisation. The rubrics for managing these dependences are also discussed in the context of future leveraging opportunities. This research reports the significant importance of ICT to capture, store and reuse knowledge in the organisational and demonstrates the need for the organisation to be e-ready