Estado de la cuestión de la educación histórica y patrimonial a través de la recreación

Estado de la cuestión acerca de la introducción de la Recreación Histórica en la educación, su influencia, y posibilidades. En este trabajo se presenta de una manera sintética la definición de la Recreación Histórica como disciplina y la historia de su desarrollo, junto con aquellos elementos que le dan entidad. Acto seguido se presenta su situación actual, y aquello que los diferentes expertos e investigadores pueden decir al respecto de su aplicación en la Enseñanza Secundaria Obligatoria, métodos de aplicación, y problemas en su difusión.<br /

Planificación estratégica de la comunicación publicitaria: Smart ForTwo Electric Drive

En las últimas décadas, el movimiento social ecologista ha ido ganando peso en la sociedad, llegando a establecerse como un valor determinante a la hora de elegir nuestros objetos de consumo. Partiendo de este marco, se ha ido desarrollando un nuevo tipo de vehículos, los eléctricos, que cubran ese segmento. El Smart Fortwo Electric Drive, además de querer establecerse dentro del mercado, quiere cambiar la relación funcional que el público establece con la marca por tamaño, creando un estilo de vida alrededor de Smart que la distinga de su competencia. Para este proyecto, pretendemos realizar una investigación de cerca y, un análisis de las debilidades y fortalezas de la marca, para poder así desarrollar la planificación estratégica. Además, pretendemos llevar a cabo una cata para comprobar qué imagen tiene el público del producto Smart.Grado en Publicidad y Relaciones Pública

Political leaders on YouTube: information and politainment in the general elections 2016 in Spain

Producción CientíficaEsta investigación aborda el estudio de YouTube en la campaña electoral de las elecciones generales del 26 de junio de 2016 (26J) en España. A través de un método de análisis de contenido descriptivo contrastado, se examina una muestra de 80 vídeos de los líderes políticos: Mariano Rajoy, Pedro Sánchez, Pablo Iglesias y Albert Rivera. Los objetivos de la investigación son conocer si existió diferencia en el consumo mediático en el período de campaña electoral frente al de campaña permanente, establecer si la respuesta de los prosumidores fue desigual en términos de participación en los períodos analizados, e indagar en categorías como la temática de los vídeos y autoría. Los resultados indican que en campaña permanente los vídeos de politainment son los más consumidos, mientras que en campaña electoral los vídeos más vistos se refieren a cuestiones informativas. El prosumo es pasivo en su producción y participación.This research addresses the study of YouTube in the electoral campaign of the General Election on June 26th, 2016 (26J) in Spain. Through a methodology of descriptive analysis of contrasted content, a sample of 80 videos of the political leaders were examined: Mariano Rajoy, Pedro Sánchez, Pablo Iglesias and Albert Rivera. The objectives of the research were to identify if there was a difference in media consumption between the electoral campaign period and the permanent campaign. Therefore, it could be established whether the response of the prosumers was unequal in terms of participation and to investigate in categories such as thematic of videos and authorship. The results reveal that the videos which contain politainment in the permanent campaign category are the most consumed, while the most viewed videos in the electoral campaign are on informative questions. The prosumers are passive: they neither produce nor participate actively

How well do RCMs and ESDs reproduce the occurrence of extreme precipitation events over Southeastern South America? A case study approach

Individual extreme precipitation eventsover Southeastern South America(SESA)during thes pringand summer time are responsible of more than 40% of the total accumulated seasonal precipitation. These extreme events are associated with the occurrence of organized convection in the region.Giventhe mesoscale features involved in their development..Fil: Solman, Silvina Alicia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; ArgentinaFil: Bettolli, Maria Laura. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; ArgentinaFil: Doyle, Moira Evelina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; ArgentinaFil: Blazquez, Josefina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; ArgentinaFil: Feijoó, Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; ArgentinaFil: Olmo, Matías Ezequiel. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ciencias de la Atmósfera y los Océanos; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Díaz, Gonzalo Martín. Ministerio de Defensa. Secretaria de Planeamiento. Servicio Meteorológico Nacional; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Balmaceda, Rocio. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ciencias de la Atmósfera y los Océanos; ArgentinaFil: Poggi, María Mercedes. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Ciencias de la Atmósfera y los Océanos; ArgentinaThe International Conference on Regional Climate CordexBeijingChinaWorld Climate Research Programm

Copyright Literacy in Spanish Library and Information Sciences (LIS) students

Copyright literacy in Spanish Library and Information Sciences (LIS) students was studied using a web survey as part of a multinational research project. The study focused on their knowledge, opinions and experiences with various aspects of copyright and intellectual property legislation and training. Results show that Spanish students are familiar with copyright and related laws at the national level, as well as with Creative Commons Licenses. However, most of respondents were very unfamiliar with topics related to the protection of rights in the digital environment and international copyright issues. Therefore, there is a need to increase information and knowledge of copyright issues in the LIS curricula, since copyright issues are already, and will continue to be in the future, a relevant part of information professionals' expertise

Copyright Literacy in Spanish Library and Information Sciences (LIS) students

[EN] Copyright literacy in Spanish Library and Information Sciences (LIS) students was studied using a web survey as part of a multinational research project. The study focused on their knowledge, opinions and experiences with various aspects of copyright and intellectual property legislation and training. Results show that Spanish students are familiar with copyright and related laws at the national level, as well as with Creative Commons Licenses. However, most of respondents were very unfamiliar with topics related to the protection of rights in the digital environment and international copyright issues. Therefore, there is a need to increase information and knowledge of copyright issues in the LIS curricula, since copyright issues are already, and will continue to be in the future, a relevant part of information professionals’ expertise.[ES] El nivel de conocimiento en temas sobre Derechos de Autor en estudiantes de Biblioteconomía y Documentación fue estudiado por medio de una encuesta web como parte de un proyecto de investigación plurinacional. El estudio se centró en el conocimiento, opiniones y experiencias de los estudiantes en varios aspectos de la legislación sobre Derechos de Autor y Propiedad Intelectual, así como en su formación. Los resultados muestran que los estudiantes españoles están familiarizados con las leyes sobre Derechos de Autor, y aquéllas relacionadas a nivel internacional, así como en las licencias Creative Commons. Sin embargo, la mayoría de los encuestados mostraron escaso conocimiento en asuntos relacionados con la protección de derechos en el entorno digital o la problemática sobre Derechos de Autor a nivel internacional. Por tanto, existe la necesidad de mejorar la información y el conocimiento acerca de los temas relacionados con los Derechos de Autor en los curricula de los estudiantes de Biblioteconomía y Documentación, dado que los problemas sobre Derechos de Autor son actualmente una parte relevante de la experiencia de los profesionales de la información, y continuarán siéndolo en el futuro.S

Paclitaxel Plus Cetuximab as Induction Chemotherapy for Patients With Locoregionally Advanced Head and Neck Squamous Cell Carcinoma Unfit for Cisplatin-Based Chemotherapy

ObjectivesInduction chemotherapy (ICT) followed by definitive treatment is an accepted non-surgical approach for locoregionally advanced head and neck squamous cell carcinoma (LA-HNSCC). However, ICT remains a challenge for cisplatin-unfit patients. We evaluated paclitaxel and cetuximab (P-C) as ICT in a cohort of LA-HNSCC patients unfit for cisplatin. Materials and MethodsThis is a retrospective analysis of patients with newly diagnosed LA-HNSCC considered unfit for cisplatin-based chemotherapy (age >70 and/or ECOG >= 2 and/or comorbidities) treated with weekly P-C followed by definitive radiotherapy and cetuximab (RT-C) between 2010 and 2017. Toxicity and objective response rate (ORR) to ICT and RT-C were collected. Median overall survival (OS) and progression-free survival (PFS) were estimated using the Kaplan-Meier method. Cox regression analysis was performed to determine baseline predictors of OS and PFS. ResultsA total of 57 patients were included. Grade 3-4 toxicity rate to ICT was 54.4%, and there was a death deemed treatment-related (G5). P-C achieved an ORR of 66.7%, including 12.3% of complete responses (CR). After P-C, 45 patients (78.9%) continued with concomitant RT-C. Twenty-six patients (45.6%) achieved a CR after definitive treatment. With a median follow-up of 21.7 months (range 1.2-94.6), median OS and PFS were 22.9 months and 10.7 months, respectively. The estimated 2-year OS and PFS rates were 48.9% and 33.7%, respectively. Disease stage had a negative impact on OS (stage IVb vs. III-IVa: HR = 2.55 [1.08-6.04], p = 0.03), with a trend towards worse PFS (HR = 1.92 [0.91-4.05], p = 0.09). Primary tumor in the larynx was associated with improved PFS but not OS (HR = 0.45 [0.22-0.92], p = 0.03, and HR = 0.69 [0.32-1.54], p = 0.37, respectively). ConclusionP-C was a well-tolerated and active ICT regimen in this cohort of LA-HNSCC patients unfit for cisplatin-based chemotherapy. P-C might represent a valid ICT option for unfit patients and may aid patient selection for definitive treatment

A deletion in SARS-CoV- 2 ORF7 identified in COVID-19 outbreak in Uruguay

The analysis of genetic diversity in SARS-CoV-2 is the focus of several studies, providing insights into how the virus emerged and evolves. Most common changes in SARS-CoV-2 are single or point nucleotide substitutions; meanwhile, insertions and deletions (indels) have been identified as a less frequent source of viral genetic variability. Here, we report the emergence of a 12-nucleotide deletion in ORF7a, resulting in a 4-amino acid in-frame deletion. The Δ12 variant was identified in viruses from patients of a single outbreak and represents the first report of this deletion in South American isolates. Phylogenetic analysis revealed that Δ12 strains belong to the lineage B.1.1 and clustered separated from the remaining Uruguayan strains. The ∆12 variant was detected in 14 patients of this outbreak by NGS sequencing and/or two rapid and economic methodologies: Sanger amplicon sequencing and capillary electrophoresis. The presence of strong molecular markers as the deletion described here are useful for tracking outbreaks and reveal a significant aspect of the SARS-CoV-2 evolution on the robustness of the virus to keep its functionality regardless loss of genetic material

Rich oleocanthal and oleacein extra virgin olive oil and inflammatory and antioxidant status in people with obesity and prediabetes. The APRIL study: A randomised, controlled crossover study

Background: Oleocanthal and oleacein are olive oil phenolic compounds with well known anti inflammatory and anti-oxidant properties. The main evidence, however, is provided by experimental studies. Few human studies have examined the health benefits of olive oils rich in these biophenols. Our aim was to assess the health properties of rich oleocanthal and oleacein extra virgin olive oil (EVOO), compared to those of common olive oil (OO), in people with prediabetes and obesity. Methods: Randomised, double-blind, crossover trial done in people aged 40e65 years with obesity (BMI 30e40 kg/m2 ) and prediabetes (HbA1c 5.7e6.4%). The intervention consisted in substituting for 1 month the oil used for food, both raw and cooked, by EVOO or OO. No changes in diet or physical activity were recommended. The primary outcome was the inflammatory status. Secondary outcomes were the oxidative status, body weight, glucose handling and lipid profile. An ANCOVA model adjusted for age, sex and treatment administration sequence was used for the statistical analysis. Results: A total of 91 patients were enrolled (33 men and 58 women) and finished the trial. A decrease in interferon-g was observed after EVOO treatment, reaching inter-treatment differences (P ¼ 0.041). Total antioxidant status increased and lipid and organic peroxides decreased after EVOO treatment, the changes reaching significance compared to OO treatment (P < 0.05). Decreases in weight, BMI and blood glucose (p < 0.05) were found after treatment with EVOO and not with OO. Conclusions: Treatment with EVOO rich in oleocanthal and oleacein differentially improved oxidative and inflammatory status in people with obesity and prediabetes.Funding for open access charge: Universidad de Málaga/CBU

Protein Kinase C δ Regulates the Depletion of Actin at the Immunological Synapse Required for Polarized Exosome Secretion by T Cells

Multivesicular bodies (MVB) are endocytic compartments that enclose intraluminal vesicles (ILVs) formed by inward budding from the limiting membrane of endosomes. In T lymphocytes, ILVs are secreted as Fas ligand-bearing, pro-apoptotic exosomes following T cell receptor (TCR)-induced fusion of MVB with the plasma membrane at the immune synapse (IS). In this study we show that protein kinase C δ (PKCδ), a novel PKC isotype activated by diacylglycerol (DAG), regulates TCR-controlled MVB polarization toward the IS and exosome secretion. Concomitantly, we demonstrate that PKCδ-interfered T lymphocytes are defective in activation-induced cell death. Using a DAG sensor based on the C1 DAG-binding domain of PKCδ and a GFP-PKCδ chimera, we reveal that T lymphocyte activation enhances DAG levels at the MVB endomembranes which mediates the association of PKCδ to MVB. Spatiotemporal reorganization of F-actin at the IS is inhibited in PKCδ-interfered T lymphocytes. Therefore, we propose PKCδ as a DAG effector that regulates the actin reorganization necessary for MVB traffic and exosome secretion