576 research outputs found
Experimental Review of Baryons in the Nuclear Medium
Inclusive studies of nuclear photoabsorption have provided clear evidence of
medium modifications but the results have not yet been explained in a model
independent way. A deeper understanding of the situation is anticipated from a
detailed experimental study of meson photoproduction from nuclei in exclusive
reactions. Recent results on meson production in photonuclear experiments
indicate a large difference between quasifree meson production from the nuclear
surface and non-quasifree components.Comment: Proceedings Baryons200
OH+ in astrophysical media: state-to-state formation rates, Einstein coefficients and inelastic collision rates with He
The rate constants required to model the OH observations in different
regions of the interstellar medium have been determined using state of the art
quantum methods.
First, state-to-state rate constants for the H+ O()
H + OH reaction have been obtained using
a quantum wave packet method. The calculations have been compared with
time-independent results to asses the accuracy of reaction probabilities at
collision energies of about 1 meV. The good agreement between the simulations
and the existing experimental cross sections in the 1 eV energy range
shows the quality of the results.
The calculated state-to-state rate constants have been fitted to an
analytical form. Second, the Einstein coefficients of OH have been obtained
for all astronomically significant ro-vibrational bands involving the
and/or electronic states.
For this purpose the potential energy curves and electric dipole transition
moments for seven electronic states of OH are calculated with {\it ab
initio} methods at the highest level and including spin-orbit terms, and the
rovibrational levels have been calculated including the empirical spin-rotation
and spin-spin terms. Third, the state-to-state rate constants for inelastic
collisions between He and OH have been calculated using a
time-independent close coupling method on a new potential energy surface. All
these rates have been implemented in detailed chemical and radiative transfer
models. Applications of these models to various astronomical sources show that
inelastic collisions dominate the excitation of the rotational levels of
OH. In the models considered the excitation resulting from the chemical
formation of OH increases the line fluxes by about 10 % or less depending
on the density of the gas
Photoproduction of pions and etas in nuclei
We calculate the cross sections for inclusive one-pion, two-pion and eta
photoproduction in nuclei in the photon energy range from 300 MeV to 900 MeV
within the framework of a semi-classical BUU transport model. Our results are
compared with existing experimental data and discussed with respect to a
calculation of the total photoabsorption cross section.Comment: 30 pages LaTeX including 13 postscript figure
Linear brain atrophy measures in multiple sclerosis and clinically isolated syndromes: A 30-year follow-up
OBJECTIVE: To determine 30-year brain atrophy rates following clinically isolated syndromes and the relationship of atrophy in the first 5 years and clinical outcomes 25 years later. METHODS: A cohort of 132 people who presented with a clinically isolated syndrome suggestive of multiple sclerosis (MS) were recruited between 1984–1987. Clinical and MRI data were collected prospectively over 30 years. Widths of the third ventricle and the medulla oblongata were used as linear atrophy measures. RESULTS: At 30 years, 27 participants remained classified as having had a clinically isolated syndrome, 34 converted to relapsing remitting MS, 26 to secondary progressive MS and 16 had died due to MS. The mean age at baseline was 31.7 years (SD 7.5) and the mean disease duration was 30.8 years (SD 0.9). Change in medullary and third ventricular width within the first 5 years, allowing for white matter lesion accrual and Expanded Disability Status Scale increases over the same period, predicted clinical outcome measures at 30 years. 1 mm of medullary atrophy within the first 5 years increased the risk for secondary progressive MS or MS related death by 30 years by 583% (OR 5.83, 95% CI 1.74 to 19.61, p<0.005), using logistic regression. CONCLUSIONS: Our findings show that brain regional atrophy within 5 years of a clinically isolated syndrome predicts progressive MS or a related death, and disability 25 years later
Star Formation Under the Outflow: The Discovery of a Non-Thermal Jet from OMC-2 FIR 3 and its Relationship to the Deeply Embedded FIR 4 Protostar
We carried out multiwavelength (0.7-5 cm), multiepoch (1994-2015) Very Large
Array (VLA) observations toward the region enclosing the bright far-IR sources
FIR 3 (HOPS 370) and FIR 4 (HOPS 108) in OMC-2. We report the detection of 10
radio sources, seven of them identified as young stellar objects. We image a
well-collimated radio jet with a thermal free-free core (VLA 11) associated
with the Class I intermediate-mass protostar HOPS 370. The jet presents several
knots (VLA 12N, 12C, 12S) of non-thermal radio emission (likely synchrotron
from shock-accelerated relativistic electrons) at distances of ~7,500-12,500 au
from the protostar, in a region where other shock tracers have been previously
identified. These knots are moving away from the HOPS 370 protostar at ~ 100
km/s. The Class 0 protostar HOPS 108, which itself is detected as an
independent, kinematically decoupled radio source, falls in the path of these
non-thermal radio knots. These results favor the previously proposed scenario
where the formation of HOPS 108 has been triggered by the impact of the HOPS
370 outflow with a dense clump. However, HOPS 108 presents a large proper
motion velocity of ~ 30 km/s, similar to that of other runaway stars in Orion,
whose origin would be puzzling within this scenario. Alternatively, an apparent
proper motion could result because of changes in the position of the centroid
of the source due to blending with nearby extended emission, variations in the
source shape, and /or opacity effects.Comment: 16 pages, 4 figures, accepted for publication in The Astrophysical
Journa
A comparative analysis of lung function and spirometry parameters in genotype-controlled natives living at low and high altitude
Background: The reference values for lung function are associated to anatomical and lung morphology parameters, but anthropometry it is not the only influencing factor: altitude and genetics are two important agents affecting respiratory physiology. Altitude and its influence on respiratory function has been studied independently of genetics, considering early and long-term acclimatization. Objective: The objective of this study is to evaluate lung function through a spirometry study in autochthonous Kichwas permanently living at low and high-altitude. Methodology: A cross-sectional study of spirometry differences between genetically matched lowland Kichwas from Limoncocha (230 m) at Amazonian basin and high-altitude Kichwas from Oyacachi (3,180 m) in Andean highlands. Chi-square method was used to analyze association or independence of categorical variables, while Student's t test was applied to comparison of means within quantitative variables. ANOVA, or in the case that the variables didn't meet the criteria of normality, Kruskal Wallis test were used to compare more than two groups. Results: People from Oyacachi (high altitude) showed a higher predicted values than those from Limonocha (low altitude). The FVC and the FEV1 were significantly greater among highlanders than lowlanders (p value < 0.001). The FEV1/FVC was significantly higher among lowlanders than highlanders for men and women. A restrictive pattern was found in 12.9% of the participants. Conclusion: Residents of Oyacachi had greater lung capacity than their peers from Limoncocha, a finding physiologically plausible according to published literature. When analyzing the spirometric patterns obtained in these populations, it was evident that no person had an obstructive pattern, while on the other hand, the restrictive pattern appeared in Limoncocha and Oyacachi populations in 12.9% although it is clear that there is a predominance of this in the individuals belonging to Limoncocha
The Structure of n-Point One-Loop Open Superstring Amplitudes
In this article we present the worldsheet integrand for one-loop amplitudes
in maximally supersymmetric superstring theory involving any number n of
massless open string states. The polarization dependence is organized into the
same BRST invariant kinematic combinations which also govern the leading string
correction to tree level amplitudes. The dimensions of the bases for both the
kinematics and the associated worldsheet integrals is found to be the unsigned
Stirling number S_3^{n-1} of first kind. We explain why the same combinatorial
structures govern on the one hand finite one-loop amplitudes of equal helicity
states in pure Yang Mills theory and on the other hand the color tensors at
quadratic alpha prime order of the color dressed tree amplitude.Comment: 75 pp, 8 figs, harvmac TeX, v2: published versio
Mapping the ionized gas of the metal-poor HII galaxy PHL 293B with MEGARA
Here we report the first spatially resolved spectroscopic study for the
galaxy PHL293B using the high-resolution GTC/MEGARA IFU. PHL293B is a local,
extremely metal-poor, high ionization galaxy. This makes PHL 293B an excellent
analogue for galaxies in the early Universe. The MEGARA aperture (~12.5''x
11.3'') covers the entire PHL 293B main body and its far-reaching ionized gas.
We created and discussed maps of all relevant emission lines, line ratios and
physical-chemical properties of the ionized ISM. The narrow emission gas
appears to be ionized mainly by massive stars according to the observed
diganostic line ratios, regardless of the position across the MEGARA aperture.
We detected low intensity broad emission components and blueshifted absorptions
in the Balmer lines (H,H) which are located in the brightest
zone of the galaxy ISM. A chemically homogeneity, across hundreds of parsecs,
is observed in O/H. We take the oxygen abundance 12+log(O/H)=7.64 0.06
derived from the PHL293B integrated spectrum as the representative metallicity
for the galaxy. Our IFU data reveal for the first time that the nebular
HeII4686 emission from PHL 293B is spatially extended and coincident with the
ionizing stellar cluster, and allow us to compute its absolute HeII ionizing
photon flux. Wolf-Rayet bumps are not detected excluding therefore Wolf-Rayet
stars as the main HeII excitation source. The origin of the nebular HeII4686 is
discussed.Comment: 14 pages, 9 Figures, 3 Tables; Accepted for publication in MNRA
Mass spectrometry-based biomarkers to detect prostate cancer: a multicentric study based on non-invasive urine collection without prior digital rectal examination
(1) Background: Prostate cancer (PCa) is the most frequently diagnosed cancer in men. Wide application of prostate specific antigen test has historically led to over-treatment, starting from excessive biopsies. Risk calculators based on molecular and clinical variables can be of value to determine the risk of PCa and as such, reduce unnecessary and invasive biopsies. Urinary molecular studies have been mostly focusing on sampling after initial intervention (digital rectal examination and/or prostate massage). (2) Methods: Building on previous proteomics studies, in this manuscript, we aimed at developing a biomarker model for PCa detection based on urine sampling without prior intervention. Capillary electrophoresis coupled to mass spectrometry was applied to acquire proteomics profiles from 970 patients from two different clinical centers. (3) Results: A case-control comparison was performed in a training set of 413 patients and 181 significant peptides were subsequently combined by a support vector machine algorithm. Independent validation was initially performed in 272 negative for PCa and 138 biopsy-confirmed PCa, resulting in an AUC of 0.81, outperforming current standards, while a second validation phase included 147 PCa patients. (4) Conclusions: This multi-dimensional biomarker model holds promise to improve the current diagnosis of PCa, by guiding invasive biopsies
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