Aplicación de gestión de almacén para mejorar la productividad en la empresa Inversiones Romero &CIA S.A.C. San Martin de Porres, 2018

La presente investigación titulada “Aplicación de la gestión de almacén para mejorar la productividad en la empresa Inversiones Romero & Cia. SAC en el distrito de S.M.P.,2018”, tiene como objetivo general, el determinar qué la aplicación de la gestión de almacén, mejora la productividad en el área de almacén de la empresa Inversiones Romero & Cia. SAC en el distrito de S.M.P.,2018. El diseño de la investigación es cuasi-experimental de tipo aplicada, debido a que busca confrontar la parte teórica con la realidad. La población de estudio estuvo conformada por los meses de junio y setiembre del año 2018, analizados antes y después de la implementación del Estudio de Trabajo. La muestra es seleccionada por conveniencia igual a la población. La técnica empleada para la recolección de datos fue la observación, y los instrumentos utilizados fueron los siguientes formatos: hojas de verificación de Toma de Tiempos, formato de cálculo del Número de Muestras, medición del Tiempo Estándar, y la ficha de estimación de Eficiencia, Eficacia y Productividad, así como el cronómetro. Finalmente, en el análisis de datos se utilizó programas como el Microsoft Excel y el SPSS V. 25, de manera descriptiva e inferencial utilizándose tablas y gráficos lineales. Según los datos ingresados al SPSS V. 25, se obtuvo como resultado que la significancia de la prueba de Wilcoxon, aplicada a la productividad Antes y Después es de 0.000, por consiguiente, al ser menor a 0.05, se rechaza la hipótesis nula y se acepta la hipótesis del investigado

Diseño geométrico y estructural de la carretera Limabamba - Rio de pesca, Distrito de Limabamba - Rodríguez de Mendoza - Amazonas

La actual tesis de ingeniería civil esta direccionada al área de trasporte, por medio de la cual se realizó el diseño geométrico y estructural de 14+200 Km del tramo: Limabamba - Río de Pesca, ubicado en el distrito de Limabamba, Provincia de Rodríguez de Mendoza, Departamento de Amazonas. En dicho tramo encontramos la carencia de infraestructura vial; dado esto, se tiene como objetivo general realizar el diseño geométrico y estructural de la carretera para mejorar el flujo vehicular, optimizando así el crecimiento económico y social de la zona. Se realizó el análisis de transito actual por medio de conteos manuales, para determinar los volúmenes de máxima demanda. A continuación, se realizó el estudio de suelos para el óptimo diseño estructural de la vía. Para tener una noción real de la situación actual de las características geométricas y estructurales, se formuló un diagnostico que permitió definir las carencias de dicha unidad de estudio. Finalmente, se planteó el diseño geométrico y estructural de la vía la cual se presentó para optimizar el uso correcto de la vía.The current civil engineering thesis is directed to the transportation area, through which the geometric and structural design of 14+200 km of the section was carried out: Limabamba - Río de Pesca, located in the district of Limabamba, Province of Rodríguez de Mendoza, Department of Amazonas. In this section we find the lack of road infrastructure; given this, the general objective is to carry out the geometric and structural design of the road to improve vehicular flow, optimizing the economic and social growth of the area. The current traffic analysis was carried out by means of manual counts, to determine the volumes of maximum demand. Next, the soil study was carried out for the optimal structural design of the road. In order to have a real notion of the current situation of the geometric and structural characteristics, a diagnosis was formulated that allowed to define the deficiencies of said unit of study. Finally, the geometric and structural design of the road was proposed, which was presented to optimize the correct use of the road.Tesi

Tibial rotational osteotomies in patients with myelodysplasia: outcomes and risk factors

BACKGROUND: Lower extremity rotational deformities in patients with lumbar level myelodypslasia are common. Standard treatment for persistent rotational deformity is tibial derotational osteotomy, with or without concomitant fibular osteotomy. There are few studies looking at the long-term results and outcomes. Thus, the purpose of this study is to determine outcomes as a function of complication rates and revision surgery rates. METHOD: A retrospective chart review of ambulatory patients …postprin

Sistema de Seguridad y Salud Ocupacional para mejorar Áreas Críticas de los Servicios Públicos de la Municipalidad de Carhuaz - 2019

La presente investigación pretende implementar un Sistema de Gestión de Seguridad y Salud Ocupacional para mejorar las áreas críticas de los Servicios Públicos de la Municipalidad de Carhuaz – 2019. Fue de tipo aplicada. La población fue conformada por 187 trabajadores del área de Servicios Públicos y la muestra por 38. Se recolectan los datos usando los datos de Recursos Humanos, cuestionario de seguridad y un Check list del área de trabajo. La confiabilidad se desarrolló en base al alfa de Cronbach, α= 0.836; se usó el SPSS 21. Como instrumentos se usó la Matriz IPERC, ficha de inspección, registro de accidentes, estadísticas de accidentes del año 2019, cuestionario dirigido al personal de la Municipalidad Provincial de Carhuaz

Videojuego para mejorar el análisis experimental del comportamiento con condicionamiento operante en la escuela profesional de psicología de una universidad privada de Trujillo, 2021

La presente investigación tuvo como principal objetivo mejorar el análisis experimental con condicionamiento operante en la escuela de psicología de una universidad privada de Trujillo, a través de la implementación de un videojuego, en el año 2021. El tipo de investigación que fue aplicada, de grado pre-experimental, además, se una ficha de registro como una herramienta para la obtención de datos, la cual ha sido validad por juicio de expertos, y se utilizó el coeficiente V de Aiken para la comprobación de esta, además se utilizó el coeficiente Alfa de Cronbach para validar su confiabilidad. Para realizar el videojuego, se utilizó la metodología SUM y su correspondiente página web, con la metodología OOHDM, las cuales tiene concepto, planificación, elaboración, beta, cierre y obtención de requerimientos, modelo conceptual, diseño navegacional, diseño de interfaz abstracta, implementación, de manera respectiva. Los resultados obtenidos al finalizar la implementación del videojuego, el aumento en la recolección de datos, teniendo un incremento en la producción de reportes, teniendo un resultado de un reporte después de dos segundos de finalizado el experimento de condicionamiento, además se obtuvo un promedio 1.2 de conexiones por minuto, también se obtuvo un porcentaje de índice de error de 1.2 por ciento en cada reporte. La población de 25 alumnos y un profesor de la escuela de psicología de una universidad privada de Trujillo, se utilizó la prueba de normalidad Shapiro Wilk para procesar los resultados del antes y después de la implementación, y con estos, se usó la prueba no paramétrica Wilcoxon para analizar cada uno de los indicadores. La investigación presente se divide en introducción, marco teórico, resultados, discusión, conclusiones, recomendaciones, finalmente la metodología de desarrollo de videojuego y desarrolla web. Se concluye que, con la implementación de videojuego, se mejora de manera significativa el análisis experimental con condicionamiento operante en la escuela de psicología de una universidad privada de Trujillo en el año 2021

Electrochemical activation of molecular nitrogen at the Ir/YSZ interface.

Nitrogen is often used as an inert background atmosphere in solid state studies of electrode and reaction kinetics, of solid state studies of transport phenomena, and in applications e.g. solid oxide fuel cells (SOFC), sensors and membranes. Thus, chemical and electrochemical reactions of oxides related to or with dinitrogen are not supposed and in general not considered. We demonstrate by a steady state electrochemical polarisation experiments complemented with in situphotoelectron spectroscopy (XPS) that at a temperature of 450 °C dinitrogen can be electrochemically activated at the three phase boundary between N2, a metal microelectrode and one of the most widely used solid oxide electrolytes—yttria stabilized zirconia (YSZ)—at potentials more negative than E = −1.25 V. The process is neither related to a reduction of the electrolyte nor to an adsorption process or a purely chemical reaction but is electrochemical in nature. Only at potentials more negative than E = −2 V did new components of Zr 3d and Y 3d signals with a lower formal charge appear, thus indicating electrochemical reduction of the electrolyte matrix. Theoretical model calculations suggest the presence of anionic intermediates with delocalized electrons at the electrode/electrolyte reaction interface. The ex situSIMS analysis confirmed that nitrogen is incorporated and migrates into the electrolyte beneath the electrode

Reproductive tract size and position score: Estimation of genetic parameters for a novel fertility trait in dairy cows.

The dairy industry is moving toward selecting animals with better fertility to decrease the economic losses linked to reproductive issues. The reproductive tract size and position score (SPS) was recently developed in physiological studies as an indicator of pregnancy rate and the number of services to conception. Cows are scored as SPS 1, 2, or 3 based on the size of their reproductive tract and its position in the pelvis, as determined by transrectal palpation. The objective of this study was to estimate genetic parameters for SPS to assess its potential as a novel fertility trait. Phenotypes were collected at the University of British Columbia's research herd from 2017 to 2020, consisting of 3,247 within- and across-lactation SPS records from 490 Holstein cows. A univariate animal model was used to estimate the variance components for SPS. Both threshold and linear models were fit under a Bayesian approach and the results were compared using the Spearman rank correlation (r) between the estimated breeding values. The 2 models ranked the animals very similarly (r = 0.99), and the linear model was selected for further analysis. Genetic correlations with other currently evaluated traits were estimated using a bivariate animal model. The posterior means (± posterior standard deviation) for heritability and repeatability within- and across-lactation were 0.113 (± 0.013), 0.242 (± 0.012), and 0.134 (± 0.014), respectively. The SPS showed null correlations with production traits and favorable correlations with traditional fertility traits, varying from -0.730 (nonreturn rate) to 0.931 (number of services). Although preliminary, these results are encouraging because SPS seems to be more heritable than and strongly genetically correlated with number of services, nonreturn rate, and first service to conception, indicating potential for effective indirect selection response on these traits from SPS genetic selection. Therefore, further studies with larger data sets to validate these findings are warranted

Does Type of Tumor Histology Impact Survival among Patients with Stage IIIB/IV Non-Small Cell Lung Cancer Treated with First-Line Doublet Chemotherapy?

Chemotherapy regimens may have differential efficacy by histology in nonsmall cell lung cancer (NSCLC). We examined the impact of histology on survival of patients (N = 2,644) with stage IIIB/IV NSCLC who received first-line cisplatin/carboplatin plus gemcitabine (C/C+G) and cisplatin/carboplatin plus a taxane (C/C+T) identified retrospectively in the SEER cancer registry (1997–2002). Patients with squamous and nonsquamous cell carcinoma survived 8.5 months and 8.1 months, respectively (P = .018). No statistically significant difference was observed in survival between C/C+G and C/C+T in both histologies. Adjusting for clinical and demographic characteristics, the effect of treatment regimen on survival did not differ by histology (P for interaction = .257). There was no statistically significant difference in hazard of death by histology in both groups. These results contrast the predictive role of histology and improved survival outcomes observed for cisplatin-pemetrexed regimens in advanced nonsquamous NSCLC

Effects of transcutaneous electrical nerve stimulation (TENS) on arterial stiffness and blood pressure in resistant hypertensive individuals: study protocol for a randomized controlled trial

Background: Resistant hypertension (RH) treatment requires an adequate and intense therapeutic approach. However, the results are not always satisfactory despite intensive treatment. Of the different pathophysiological mechanisms involved in the pathogenesis of RH, sympathetic overstimulation and therapies that block the sympathetic system have been widely studied. These approaches, however, are invasive and expensive. Another possible approach is by transcutaneous electrical nerve stimulation (TENS), a noninvasive method that modulates activity by using low-frequency transcutaneous electrical stimulation to inhibit primary afferent pathways. Thus, the current study will evaluate the effect of applying TENS in the cervicothoracic region of subjects with RH and will seek to develop a new low-cost and readily available therapy to treat this group of hypertensive individuals. Methods/design: This is a randomized, single blind (subject), parallel-assignment study controlled with a sham group and including participants aged 40 to 70 years with resistant hypertension. The trial has two arms: the treatment and control (sham group). The treatment group will be submitted to the stimulation procedure (TENS). The sham group will not be submitted to stimulation. The primary outcomes will be a reduction in the peripheral blood pressure and adverse events. The secondary outcomes will be a reduction the central blood pressure. The study will last 30 days. The sample size was calculated assuming an alpha error of 5 % to reject the null hypothesis with a statistical power of 80 %, thereby resulting in 28 participants per group (intervention versus sham). Discussion: In recent decades, RH has become very common and costly. Adequate control requires several drugs, and in many cases, treatment is not successful. Sympathetic nervous system inhibition by renal denervation and central inhibition have significant effects in reducing BP; however, these treatments are costly and invasive. Another type of sympathetic nervous system inhibition can also be noninvasively achieved by electric current. Therefore, the application of TENS may be a new therapeutic option for treating resistant hypertensive individuals. Trial Registration: Clinical Trials NCT0236597

Childhood loneliness as a predictor of adolescent depressive symptoms: an 8-year longitudinal study

Childhood loneliness is characterised by children’s perceived dissatisfaction with aspects of their social relationships. This 8-year prospective study investigates whether loneliness in childhood predicts depressive symptoms in adolescence, controlling for early childhood indicators of emotional problems and a sociometric measure of peer social preference. 296 children were tested in the infant years of primary school (T1 5 years of age), in the upper primary school (T2 9 years of age) and in secondary school (T3 13 years of age). At T1, children completed the loneliness assessment and sociometric interview. Their teachers completed externalisation and internalisation rating scales for each child. At T2, children completed a loneliness assessment, a measure of depressive symptoms, and the sociometric interview. At T3, children completed the depressive symptom assessment. An SEM analysis showed that depressive symptoms in early adolescence (age 13) were predicted by reports of depressive symptoms at age 8, which were themselves predicted by internalisation in the infant school (5 years). The interactive effect of loneliness at 5 and 9, indicative of prolonged loneliness in childhood, also predicted depressive symptoms at age 13. Parent and peer-related loneliness at age 5 and 9, peer acceptance variables, and duration of parent loneliness did not predict depression. Our results suggest that enduring peer-related loneliness during childhood constitutes an interpersonal stressor that predisposes children to adolescent depressive symptoms. Possible mediators are discussed