Music distraction among young drivers: analysis by gender and experience

The aim of this study was to quantify the probability of committing a speed infraction by young drivers and to investigate to what extent listening music could affect young drivers’ emotions as well as their driving performances at the wheel. To achieve this aim, employing Bayesian networks, the study analysed different music styles, in which they resulted in sample drivers’ speed infractions. Gender and drivers’ experiences at the wheel were the other factors, which were taken into account when interpreting the study results. Variables taken into account in this study included type of music whilst driving, gender of drivers, and drivers’ driving experiences. These variables further incorporated into the study of other telemetric variables including acceleration, number of revolutions per minute (RPM) of the engine, brake, traffic, and other types of infractions other than speed, which were considered as dependent variables. A driving simulator was used, and different driving simulation studies were carried out with young people aged between 20 and 28 years. Each participant carried out three simulations by listening to different type of music in each journey. The study defined a conceptual model in which the data were analysed and evaluated mathematically through Bayesian networks. A sensitivity analysis was performed to evaluate the influence of music on driving speed. Based on the different variables, the study further analysed the probability of speed infractions committed by drivers and their adequate speed. The range of frequency probabilities varied between 96.32% (which corresponds to experienced male drivers who do not listen to music) and 79.38% (which corresponds to less-experienced female drivers who listen to music), which resulted in their happiness or aggression.FEDER (Fondo Europeo de Desarrollo Regional) for developing Castilla y Le´on´s region. *e title of the project is “Modelizaci´on mediante t´ecnicas de machine learning de la influencia de las distracciones del conductor en la seguridad vial-Modeling the influence of driver´s distractions on road safety through machine learning techniques.” Ref. BU300P1

Noisy continuous--opinion dynamics

We study the Deffuant et al. model for continuous--opinion dynamics under the influence of noise. In the original version of this model, individuals meet in random pairwise encounters after which they compromise or not depending of a confidence parameter. Free will is introduced in the form of noisy perturbations: individuals are given the opportunity to change their opinion, with a given probability, to a randomly selected opinion inside the whole opinion space. We derive the master equation of this process. One of the main effects of noise is to induce an order-disorder transition. In the disordered state the opinion distribution tends to be uniform, while for the ordered state a set of well defined opinion groups are formed, although with some opinion spread inside them. Using a linear stability analysis we can derive approximate conditions for the transition between opinion groups and the disordered state. The master equation analysis is compared with direct Monte-Carlo simulations. We find that the master equation and the Monte-Carlo simulations do not always agree due to finite-size induced fluctuations that we analyze in some detail

Diffusing opinions in bounded confidence processes

We study the effects of diffusing opinions on the Deffuant et al. model for continuous opinion dynamics. Individuals are given the opportunity to change their opinion, with a given probability, to a randomly selected opinion inside an interval centered around the present opinion. We show that diffusion induces an order-disorder transition. In the disordered state the opinion distribution tends to be uniform, while for the ordered state a set of well defined opinion clusters are formed, although with some opinion spread inside them. If the diffusion jumps are not large, clusters coalesce, so that weak diffusion favors opinion consensus. A master equation for the process described above is presented. We find that the master equation and the Monte-Carlo simulations do not always agree due to finite-size induced fluctuations. Using a linear stability analysis we can derive approximate conditions for the transition between opinion clusters and the disordered state. The linear stability analysis is compared with Monte Carlo simulations. Novel interesting phenomena are analyzed

The sodium transporter encoded by the HKT1;2 gene modulates sodium/potassium homeostasis in tomato shoots under salinity

[EN] Excessive soil salinity diminishes crop yield and quality. In a previous study in tomato, we identified two closely linked genes encoding HKT1-like transporters, HKT1;1 and HKT1;2, as candidate genes for a major quantitative trait locus (kc7.1) related to shoot Na+/K+ homeostasis - a major salt tolerance trait - using two populations of recombinant inbred lines (RILs). Here, we determine the effectiveness of these genes in conferring improved salt tolerance by using two near-isogenic lines (NILs) that were homozygous for either the Solanum lycopersicum allele (NIL17) or for the Solanum cheesmaniae allele (NIL14) at both HKT1 loci; transgenic lines derived from these NILs in which each HKT1;1 and HKT1;2 had been silenced by stable transformation were also used. Silencing of ScHKT1;2 and SlHKT1;2 altered the leaf Na+/K+ ratio and caused hypersensitivity to salinity in plants cultivated under transpiring conditions, whereas silencing SlHKT1;1/ScHKT1;1 had a lesser effect. These results indicate that HKT1;2 has the more significant role in Na+ homeostasis and salinity tolerance in tomato.We thank Dr Espen Granum for critically reading the manuscript, Maria Isabel Gaspar Vidal and Elena Sanchez Romero for technical assistance, the Instrumental Technical Service at EEZ-CSIC for DNA sequencing and ICP-OES mineral analysis and Michael O'Shea for proofreading the text. In addition, we thank Dr Ana P. Ortega who assisted in preliminary experiments. This work was supported by ERDF-cofinanced grants, AGL2010-17090 and AGL2013-41733-R (A.B.), AGL2015-64991-C3-3-R (V.M.) and AGL2014-56675-R (M.J.A.) from the Spanish "Ministerio de Economia, Industria y Competitividad'; CVI-7558, Proyecto de Excelencia, from Junta de Andalucia (A.B); and the Australian Research Council (ARC) for Centre of Excellence (CE14010008) and Future Fellowship (FT130100709) funding (M.G.). N.J-P. was supported by an FPI program BES-2011-046096 and her stay in M.G.'s lab by a short-stay EEBB-I-14-08682, both from the Spanish from "Ministerio de Economia Industria y Competitividad'. The authors have no conflict of interest to declare.Jaime-Perez, N.; Pineda Chaza, BJ.; García Sogo, B.; Atarés Huerta, A.; Athman, A.; Byrt, CS.; Olias, R.... (2017). The sodium transporter encoded by the HKT1;2 gene modulates sodium/potassium homeostasis in tomato shoots under salinity. Plant Cell & Environment. 40(5):658-671. https://doi.org/10.1111/pce.12883S65867140

Quenched charmonium spectrum

We study charmonium using the standard relativistic formalism in the quenched approximation, on a set of lattices with isotropic lattice spacings ranging from 0.1 to 0.04 fm. We concentrate on the calculation of the hyperfine splitting between eta_c and J/psi, aiming for a controlled continuum extrapolation of this quantity. The splitting extracted from the non-perturbatively improved clover Dirac operator shows very little dependence on the lattice spacing for $a \leq 0.1$ fm. The dependence is much stronger for Wilson and tree-level improved clover operators, but they still yield consistent extrapolations if sufficiently fine lattices, $a \leq 0.07$ fm ($a M(\eta_c) \leq 1$), are used. Our result for the hyperfine splitting is 77(2)(6) MeV (where Sommer's parameter, r_0, is used to fix the scale). This value remains about 30% below experiment. Dynamical fermions and OZI-forbidden diagrams both contribute to the remainder. Results for the eta_c and J/psi wave functions are also presented.Comment: 22 pages, 7 figure

The first ALMA view of IRAS 16293-2422: Direct detection of infall onto source B and high-resolution kinematics of source A

Aims: We focus on the kinematical properties of a proto-binary to study the infall and rotation of gas towards its two protostellar components. Methods: We present ALMA Science Verification observations with high-spectral resolution of IRAS 16293-2422 at 220.2 GHz. The wealth of molecular lines in this source and the very high spectral resolution offered by ALMA allow us to study the gas kinematics with unprecedented detail. Results: We present the first detection of an inverse P-Cygni profile towards source B in the three brightest lines. The line profiles are fitted with a simple two-layer model to derive an infall rate of 4.5x10^-5 Msun/yr. This infall detection would rule-out the previously suggested possibility that source B is a T Tauri star. A position velocity diagram for source A shows evidence for rotation with an axis close to the line-of-sight.Comment: Accepted by A&A Letters. 4 pages, 3 figures, 3 appendices (one for Tables, one for additional figures). This second version includes small language modifications and changes to keep the letter within the 4 page limi

Scarce evidence of the causal role of germline mutations in UNC5C in hereditary colorectal cancer and polyposis

Germline mutations in UNC5C have been suggested to increase colorectal cancer (CRC) risk, thus causing hereditary CRC. However, the evidence gathered thus far is insufficient to include the study of the UNC5C gene in the routine genetic testing of familial CRC. Here we aim at providing a more conclusive answer about the contribution of germline UNC5C mutations to genetically unexplained hereditary CRC and/or polyposis cases. To achieve this goal we sequenced the coding region and exon-intron boundaries of UNC5C in 544 familial CRC or polyposis patients (529 families), using a technique that combines pooled DNA amplification and massively parallel sequencing. A total of eight novel or rare variants, all missense, were identified in eight families. Co-segregation data in the families and association results in case-control series are not consistent with a causal effect for 7 of the 8 identified variants, including c.1882_1883delinsAA (p.A628K), previously described as a disease-causing mutation. One variant, c.2210G > A (p.S737N), remained unclassified. In conclusion, our results suggest that the contribution of germline mutations in UNC5C to hereditary colorectal cancer and to polyposis cases is negligible

Training for innovation in Spain

The capacity for innovation of an organisation largely depends on its ability to acquire and develop new knowledge. Training is particularly important in this process, as it allows employees to constantly acquire new competences. This study provides a preliminary picture of the situation of training for innovation in Spain, and identifies the characteristics of companies offering training for innovation. Results show that 35.3% of Spanish companies undertake innovation processes and 22.3% offer training related to these innovation processes. For the 82% of these companies training helped the innovation process, so training is an important tool for innovative change

Plasma coenzyme Q10 status is impaired in selected genetic conditions.

Identifying diseases displaying chronic low plasma Coenzyme Q10 (CoQ) values may be important to prevent possible cardiovascular dysfunction. The aim of this study was to retrospectively evaluate plasma CoQ concentrations in a large cohort of pediatric and young adult patients. We evaluated plasma CoQ values in 597 individuals (age range 1 month to 43 years, average 11 years), studied during the period 2005-2016. Patients were classified into 6 different groups: control group of healthy participants, phenylketonuric patients (PKU), patients with mucopolysaccharidoses (MPS), patients with other inborn errors of metabolism (IEM), patients with neurogenetic diseases, and individuals with neurological diseases with no genetic diagnosis. Plasma total CoQ was measured by reverse-phase high-performance liquid chromatography with electrochemical detection and ultraviolet detection at 275 nm. ANOVA with Bonferroni correction showed that plasma CoQ values were significantly lower in the PKU and MPS groups than in controls and neurological patients. The IEM group showed intermediate values that were not significantly different from those of the controls. In PKU patients, the Chi-Square test showed a significant association between having low plasma CoQ values and being classic PKU patients. The percentage of neurogenetic and other neurological patients with low CoQ values was low (below 8%). In conclusión, plasma CoQ monitoring in selected groups of patients with different IEM (especially in PKU and MPS patients, but also in IEM under protein-restricted diets) seems advisable to prevent the possibility of a chronic blood CoQ suboptimal status in such groups of patients